Psychological and Demographic Characteristics of 368 Patients with Dissociative Seizures: Data from the CODES Cohort

Laura Goldstein; Emily J. Robinson; John Mellers; Jon Stone; Alan Carson; Trudie Chalder; Markus Reuber; Carole Eastwood; Sabine Landau; Paul McCrone; Michele Moore; Iris Mosweu; Joanna Murray; Iain Perdue; Izabela Pilecka; Mark Richardson; Nick Medford

doi:10.1017/S0033291720001051

Psychological and Demographic Characteristics of 368 Patients with Dissociative Seizures: Data from the CODES Cohort

Laura Goldstein, Emily J. Robinson, John Mellers, Jon Stone, Alan Carson, Trudie Chalder, Markus Reuber, Carole Eastwood, Sabine Landau, Paul McCrone, Michele Moore, Iris Mosweu, Joanna Murray, Iain Perdue, Izabela Pilecka, Mark Richardson, Nick Medford

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Abstract

Background We examined demographic, clinical, and psychological characteristics of a large cohort (n = 368) of adults with dissociative seizures (DS) recruited to the CODES randomised controlled trial (RCT) and explored differences associated with age at onset of DS, gender, and DS semiology.MethodsPrior to randomisation within the CODES RCT, we collected demographic and clinical data on 368 participants. We assessed psychiatric comorbidity using the Mini-International Neuropsychiatric Interview (M.I.N.I.) and a screening measure of personality disorder and measured anxiety, depression, psychological distress, somatic symptom burden, emotional expression, functional impact of DS, avoidance behaviour, and quality of life. We undertook comparisons based on reported age at DS onset.

Original language	English
Journal	Psychological Medicine
Early online date	11 May 2020
DOIs	https://doi.org/10.1017/S0033291720001051
Publication status	E-pub ahead of print - 11 May 2020

Keywords

Age at onset
dissociative seizures
functional impairment
psychopathology
quality of life

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Goldstein et al CLEAN COPY FOR MISAccepted author manuscript, 1.23 MB

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Goldstein, L., Robinson, E. J., Mellers, J., Stone, J., Carson, A., Chalder, T., Reuber, M., Eastwood, C., Landau, S., McCrone, P., Moore, M., Mosweu, I., Murray, J., Perdue, I., Pilecka, I., Richardson, M., & Medford, N. (2020). Psychological and Demographic Characteristics of 368 Patients with Dissociative Seizures: Data from the CODES Cohort. Psychological Medicine. Advance online publication. https://doi.org/10.1017/S0033291720001051

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abstract = "Background We examined demographic, clinical, and psychological characteristics of a large cohort (n = 368) of adults with dissociative seizures (DS) recruited to the CODES randomised controlled trial (RCT) and explored differences associated with age at onset of DS, gender, and DS semiology.MethodsPrior to randomisation within the CODES RCT, we collected demographic and clinical data on 368 participants. We assessed psychiatric comorbidity using the Mini-International Neuropsychiatric Interview (M.I.N.I.) and a screening measure of personality disorder and measured anxiety, depression, psychological distress, somatic symptom burden, emotional expression, functional impact of DS, avoidance behaviour, and quality of life. We undertook comparisons based on reported age at DS onset.",

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author = "Laura Goldstein and Robinson, {Emily J.} and John Mellers and Jon Stone and Alan Carson and Trudie Chalder and Markus Reuber and Carole Eastwood and Sabine Landau and Paul McCrone and Michele Moore and Iris Mosweu and Joanna Murray and Iain Perdue and Izabela Pilecka and Mark Richardson and Nick Medford",

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Goldstein, L , Robinson, EJ, Mellers, J, Stone, J, Carson, A, Chalder, T, Reuber, M, Eastwood, C, Landau, S, McCrone, P, Moore, M, Mosweu, I, Murray, J, Perdue, I , Pilecka, I , Richardson, M & Medford, N 2020, 'Psychological and Demographic Characteristics of 368 Patients with Dissociative Seizures: Data from the CODES Cohort', Psychological Medicine. https://doi.org/10.1017/S0033291720001051

TY - JOUR

T1 - Psychological and Demographic Characteristics of 368 Patients with Dissociative Seizures: Data from the CODES Cohort

AU - Goldstein, Laura

AU - Robinson, Emily J.

AU - Mellers, John

AU - Stone, Jon

AU - Carson, Alan

AU - Chalder, Trudie

AU - Reuber, Markus

AU - Eastwood, Carole

AU - Landau, Sabine

AU - McCrone, Paul

AU - Moore, Michele

AU - Mosweu, Iris

AU - Murray, Joanna

AU - Perdue, Iain

AU - Pilecka, Izabela

AU - Richardson, Mark

AU - Medford, Nick

PY - 2020/5/11

Y1 - 2020/5/11

N2 - Background We examined demographic, clinical, and psychological characteristics of a large cohort (n = 368) of adults with dissociative seizures (DS) recruited to the CODES randomised controlled trial (RCT) and explored differences associated with age at onset of DS, gender, and DS semiology.MethodsPrior to randomisation within the CODES RCT, we collected demographic and clinical data on 368 participants. We assessed psychiatric comorbidity using the Mini-International Neuropsychiatric Interview (M.I.N.I.) and a screening measure of personality disorder and measured anxiety, depression, psychological distress, somatic symptom burden, emotional expression, functional impact of DS, avoidance behaviour, and quality of life. We undertook comparisons based on reported age at DS onset.

AB - Background We examined demographic, clinical, and psychological characteristics of a large cohort (n = 368) of adults with dissociative seizures (DS) recruited to the CODES randomised controlled trial (RCT) and explored differences associated with age at onset of DS, gender, and DS semiology.MethodsPrior to randomisation within the CODES RCT, we collected demographic and clinical data on 368 participants. We assessed psychiatric comorbidity using the Mini-International Neuropsychiatric Interview (M.I.N.I.) and a screening measure of personality disorder and measured anxiety, depression, psychological distress, somatic symptom burden, emotional expression, functional impact of DS, avoidance behaviour, and quality of life. We undertook comparisons based on reported age at DS onset.

KW - Age at onset

KW - dissociative seizures

KW - functional impairment

KW - psychopathology

KW - quality of life

UR - http://www.scopus.com/inward/record.url?scp=85085060355&partnerID=8YFLogxK

U2 - 10.1017/S0033291720001051

DO - 10.1017/S0033291720001051

M3 - Article

SN - 0033-2917

JO - Psychological Medicine

JF - Psychological Medicine

ER -

Psychological and Demographic Characteristics of 368 Patients with Dissociative Seizures: Data from the CODES Cohort

Abstract

Keywords

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