TY - JOUR
T1 - Psychometric validation of the 15-item patient health questionnaire – Anxiety and depression scale (PHQ-ADS) to assess psychological distress in breast cancer survivors
AU - Ibrahimi, Ereza
AU - Fawson, Sophie
AU - Hughes, Lyndsay. D
AU - Chilcot, Joseph
N1 - Publisher Copyright:
© 2024 The Author(s)
PY - 2024/3/27
Y1 - 2024/3/27
N2 - Objective: Psychological distress persists amongst breast cancer survivors, so reliable assessment of symptoms is essential. The Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS) is a composite measure of depression and anxiety and has been used to measure distress. This study aimed to evaluate the psychometric properties of the PHQ-ADS within breast cancer survivors. Method: Breast cancer survivors (N = 280) were recruited online and followed up at 12-months. Depression (PHQ-8) and anxiety (GAD-7) items formed the composite PHQ-ADS score. Additional measures included: distress thermometer (convergent validity), fear of cancer recurrence and COVID distress (discriminant validity), and self-compassion (predictive validity). Confirmatory factor analysis (CFA) using weighted least squares mean and variance adjusted estimation was undertaken. Results: One, two, and bifactor models underlying the PHQ-ADS were evaluated. The bifactor model had the most appropriate model fit overall. Omega hierarchical for the general distress factor was 0.914, accounting for 82% of explained variance. This suggests the PHQ-ADS is sufficiently unidimensional to warrant use of a total composite score. The PHQ-ADS demonstrated strong convergent and moderate discriminant validity. Self-compassion was an independent predictor of distress at 12-months. Conclusions: The PHQ-ADS is a valid measure for psychological distress in breast cancer survivors prescribed hormone therapy.
AB - Objective: Psychological distress persists amongst breast cancer survivors, so reliable assessment of symptoms is essential. The Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS) is a composite measure of depression and anxiety and has been used to measure distress. This study aimed to evaluate the psychometric properties of the PHQ-ADS within breast cancer survivors. Method: Breast cancer survivors (N = 280) were recruited online and followed up at 12-months. Depression (PHQ-8) and anxiety (GAD-7) items formed the composite PHQ-ADS score. Additional measures included: distress thermometer (convergent validity), fear of cancer recurrence and COVID distress (discriminant validity), and self-compassion (predictive validity). Confirmatory factor analysis (CFA) using weighted least squares mean and variance adjusted estimation was undertaken. Results: One, two, and bifactor models underlying the PHQ-ADS were evaluated. The bifactor model had the most appropriate model fit overall. Omega hierarchical for the general distress factor was 0.914, accounting for 82% of explained variance. This suggests the PHQ-ADS is sufficiently unidimensional to warrant use of a total composite score. The PHQ-ADS demonstrated strong convergent and moderate discriminant validity. Self-compassion was an independent predictor of distress at 12-months. Conclusions: The PHQ-ADS is a valid measure for psychological distress in breast cancer survivors prescribed hormone therapy.
UR - http://www.scopus.com/inward/record.url?scp=85189530211&partnerID=8YFLogxK
U2 - 10.1016/j.genhosppsych.2024.03.004
DO - 10.1016/j.genhosppsych.2024.03.004
M3 - Article
SN - 0163-8343
VL - 88
SP - 68
EP - 74
JO - GENERAL HOSPITAL PSYCHIATRY
JF - GENERAL HOSPITAL PSYCHIATRY
ER -
