Abstract
The associations between hormonal changes and psychiatric disorders have long been recognized, but only in recent decades have the underlying mechanisms begun to be understood. A renewed interest in the associations linking stressful early life events, hypothalamic-pituitary-adrenal (HPA) axis dysregulation, inflammatory processes, and potential vulnerability to depression, psychosis, and posttraumatic stress disorder (PTSD) has prompted a resurgence of research in this field. Although the association between reproductive hormone changes and psychiatric disorders has been less well studied, there is likewise a growing clinical recognition of the burden of postpartum psychopathology and a new impetus for research progress in this area. A full account of how each endocrine system influences neurobehavioral function is beyond the scope of a single chapter; we focus here on summarizing the most firmly established findings from classic literature in the field, and on providing an overview of some recent promising research findings.
| Original language | English |
|---|---|
| Title of host publication | The American Psychiatric Association Publishing Textbook of Psychopharmacology |
| Subtitle of host publication | Fifth Edition |
| Editors | Alan F. Schatzberg, Charles B. Nemeroff |
| Edition | 5 |
| ISBN (Electronic) | 9781615371228 |
| DOIs | |
| Publication status | Published - 1 May 2017 |