Psychosocial Impact of False-Positive Newborn Screening Results: A Scoping Review

Jane Chudleigh; Pru Holder

doi:10.3390/children11050507

Psychosocial Impact of False-Positive Newborn Screening Results: A Scoping Review

Jane Chudleigh, Pru Holder

Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation

King's College London

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Psychosocial consequences of false-positive results following newborn bloodspot screening have been identified as a potential risk to this highly successful public health initiative. A scoping review was undertaken in October 2023 underpinned by the Arksey and O'Malley framework. Twenty-four papers were included in the review, many of which focused on cystic fibrosis. The results indicated that impact of false-positive results is variable; some studies suggest false-positive results have the potential to result in negative sequelae including increased stress and changes in parental perceptions of their child, while others suggest these impacts are transient and, in some instances, may even lead to positive outcomes. Further evidence is needed to ensure the representation of other conditions included in newborn bloodspot screening and to support strategies to overcome potential negative sequela.

Original language	English
Article number	507
Journal	Children (Basel, Switzerland)
Volume	11
Issue number	5
DOIs	https://doi.org/10.3390/children11050507
Publication status	Published - 24 Apr 2024

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10.3390/children11050507

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title = "Psychosocial Impact of False-Positive Newborn Screening Results: A Scoping Review",

abstract = "Psychosocial consequences of false-positive results following newborn bloodspot screening have been identified as a potential risk to this highly successful public health initiative. A scoping review was undertaken in October 2023 underpinned by the Arksey and O'Malley framework. Twenty-four papers were included in the review, many of which focused on cystic fibrosis. The results indicated that impact of false-positive results is variable; some studies suggest false-positive results have the potential to result in negative sequelae including increased stress and changes in parental perceptions of their child, while others suggest these impacts are transient and, in some instances, may even lead to positive outcomes. Further evidence is needed to ensure the representation of other conditions included in newborn bloodspot screening and to support strategies to overcome potential negative sequela.",

author = "Jane Chudleigh and Pru Holder",

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AU - Chudleigh, Jane

AU - Holder, Pru

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N2 - Psychosocial consequences of false-positive results following newborn bloodspot screening have been identified as a potential risk to this highly successful public health initiative. A scoping review was undertaken in October 2023 underpinned by the Arksey and O'Malley framework. Twenty-four papers were included in the review, many of which focused on cystic fibrosis. The results indicated that impact of false-positive results is variable; some studies suggest false-positive results have the potential to result in negative sequelae including increased stress and changes in parental perceptions of their child, while others suggest these impacts are transient and, in some instances, may even lead to positive outcomes. Further evidence is needed to ensure the representation of other conditions included in newborn bloodspot screening and to support strategies to overcome potential negative sequela.

AB - Psychosocial consequences of false-positive results following newborn bloodspot screening have been identified as a potential risk to this highly successful public health initiative. A scoping review was undertaken in October 2023 underpinned by the Arksey and O'Malley framework. Twenty-four papers were included in the review, many of which focused on cystic fibrosis. The results indicated that impact of false-positive results is variable; some studies suggest false-positive results have the potential to result in negative sequelae including increased stress and changes in parental perceptions of their child, while others suggest these impacts are transient and, in some instances, may even lead to positive outcomes. Further evidence is needed to ensure the representation of other conditions included in newborn bloodspot screening and to support strategies to overcome potential negative sequela.

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JO - Children (Basel, Switzerland)

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ER -

Psychosocial Impact of False-Positive Newborn Screening Results: A Scoping Review

Abstract

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