Quantitative microvessel analysis with 3-D super-resolution ultrasound and velocity mapping

Sevan Harput; Matthieu Toulemonde; Alessandro Ramalli; Kirsten Christensen-Jeffries; Enrico Boni; Piero Tortoli; Chris Dunsby; Meng Xing Tang

doi:10.1109/IUS46767.2020.9251336

Quantitative microvessel analysis with 3-D super-resolution ultrasound and velocity mapping

Sevan Harput, Matthieu Toulemonde, Alessandro Ramalli, Kirsten Christensen-Jeffries, Enrico Boni, Piero Tortoli, Chris Dunsby, Meng Xing Tang

Biomedical Engineering Department

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

6 Citations (Scopus)

Abstract

Medical image analysis is becoming increasingly accessible in the clinic. Computed tomography (CT) or magnetic resonance imaging (MRI) scans are usually post-processed to generate a 3-D visualization of the human body for surgical assistance or extract quantitative data to provide additional diagnostic information. Three dimensional super-resolution ultrasound (SR US) imaging can provide similar information at a micro-level without the high cost or ionising radiation. In this study, we implemented a high volumetric-rate 3-D SR US imaging with a 2-D spiral-shaped array and imaged an in vitro microvascular structure. From the 3-D SR US images clinically relevant parameters, such as microvascular flow rate, microvessel density and tortuosity, were extracted and compared with the ground truth.

Original language	English
Title of host publication	IUS 2020 - International Ultrasonics Symposium, Proceedings
Publisher	IEEE Computer Society Press
ISBN (Electronic)	9781728154480
DOIs	https://doi.org/10.1109/IUS46767.2020.9251336
Publication status	Published - 7 Sept 2020
Event	2020 IEEE International Ultrasonics Symposium, IUS 2020 - Las Vegas, United States Duration: 7 Sept 2020 → 11 Sept 2020

Publication series

Name	IEEE International Ultrasonics Symposium, IUS
Volume	2020-September
ISSN (Print)	1948-5719
ISSN (Electronic)	1948-5727

Conference

Conference	2020 IEEE International Ultrasonics Symposium, IUS 2020
Country/Territory	United States
City	Las Vegas
Period	7/09/2020 → 11/09/2020

Access to Document

10.1109/IUS46767.2020.9251336

Cite this

Harput, S., Toulemonde, M., Ramalli, A., Christensen-Jeffries, K., Boni, E., Tortoli, P., Dunsby, C., & Tang, M. X. (2020). Quantitative microvessel analysis with 3-D super-resolution ultrasound and velocity mapping. In IUS 2020 - International Ultrasonics Symposium, Proceedings Article 9251336 (IEEE International Ultrasonics Symposium, IUS; Vol. 2020-September). IEEE Computer Society Press. https://doi.org/10.1109/IUS46767.2020.9251336

@inbook{de3cf6efb8dc4ae8a81041fe8b3b43fb,

title = "Quantitative microvessel analysis with 3-D super-resolution ultrasound and velocity mapping",

abstract = "Medical image analysis is becoming increasingly accessible in the clinic. Computed tomography (CT) or magnetic resonance imaging (MRI) scans are usually post-processed to generate a 3-D visualization of the human body for surgical assistance or extract quantitative data to provide additional diagnostic information. Three dimensional super-resolution ultrasound (SR US) imaging can provide similar information at a micro-level without the high cost or ionising radiation. In this study, we implemented a high volumetric-rate 3-D SR US imaging with a 2-D spiral-shaped array and imaged an in vitro microvascular structure. From the 3-D SR US images clinically relevant parameters, such as microvascular flow rate, microvessel density and tortuosity, were extracted and compared with the ground truth.",

author = "Sevan Harput and Matthieu Toulemonde and Alessandro Ramalli and Kirsten Christensen-Jeffries and Enrico Boni and Piero Tortoli and Chris Dunsby and Tang, {Meng Xing}",

year = "2020",

month = sep,

day = "7",

doi = "10.1109/IUS46767.2020.9251336",

language = "English",

series = "IEEE International Ultrasonics Symposium, IUS",

publisher = "IEEE Computer Society Press",

booktitle = "IUS 2020 - International Ultrasonics Symposium, Proceedings",

note = "2020 IEEE International Ultrasonics Symposium, IUS 2020 ; Conference date: 07-09-2020 Through 11-09-2020",

}

Harput, S, Toulemonde, M, Ramalli, A, Christensen-Jeffries, K, Boni, E, Tortoli, P, Dunsby, C & Tang, MX 2020, Quantitative microvessel analysis with 3-D super-resolution ultrasound and velocity mapping. in IUS 2020 - International Ultrasonics Symposium, Proceedings., 9251336, IEEE International Ultrasonics Symposium, IUS, vol. 2020-September, IEEE Computer Society Press, 2020 IEEE International Ultrasonics Symposium, IUS 2020, Las Vegas, United States, 7/09/2020. https://doi.org/10.1109/IUS46767.2020.9251336

Quantitative microvessel analysis with 3-D super-resolution ultrasound and velocity mapping. / Harput, Sevan; Toulemonde, Matthieu; Ramalli, Alessandro et al.
IUS 2020 - International Ultrasonics Symposium, Proceedings. IEEE Computer Society Press, 2020. 9251336 (IEEE International Ultrasonics Symposium, IUS; Vol. 2020-September).

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

TY - CHAP

T1 - Quantitative microvessel analysis with 3-D super-resolution ultrasound and velocity mapping

AU - Harput, Sevan

AU - Toulemonde, Matthieu

AU - Ramalli, Alessandro

AU - Christensen-Jeffries, Kirsten

AU - Boni, Enrico

AU - Tortoli, Piero

AU - Dunsby, Chris

AU - Tang, Meng Xing

PY - 2020/9/7

Y1 - 2020/9/7

N2 - Medical image analysis is becoming increasingly accessible in the clinic. Computed tomography (CT) or magnetic resonance imaging (MRI) scans are usually post-processed to generate a 3-D visualization of the human body for surgical assistance or extract quantitative data to provide additional diagnostic information. Three dimensional super-resolution ultrasound (SR US) imaging can provide similar information at a micro-level without the high cost or ionising radiation. In this study, we implemented a high volumetric-rate 3-D SR US imaging with a 2-D spiral-shaped array and imaged an in vitro microvascular structure. From the 3-D SR US images clinically relevant parameters, such as microvascular flow rate, microvessel density and tortuosity, were extracted and compared with the ground truth.

AB - Medical image analysis is becoming increasingly accessible in the clinic. Computed tomography (CT) or magnetic resonance imaging (MRI) scans are usually post-processed to generate a 3-D visualization of the human body for surgical assistance or extract quantitative data to provide additional diagnostic information. Three dimensional super-resolution ultrasound (SR US) imaging can provide similar information at a micro-level without the high cost or ionising radiation. In this study, we implemented a high volumetric-rate 3-D SR US imaging with a 2-D spiral-shaped array and imaged an in vitro microvascular structure. From the 3-D SR US images clinically relevant parameters, such as microvascular flow rate, microvessel density and tortuosity, were extracted and compared with the ground truth.

UR - http://www.scopus.com/inward/record.url?scp=85097877388&partnerID=8YFLogxK

U2 - 10.1109/IUS46767.2020.9251336

DO - 10.1109/IUS46767.2020.9251336

M3 - Conference paper

AN - SCOPUS:85097877388

T3 - IEEE International Ultrasonics Symposium, IUS

BT - IUS 2020 - International Ultrasonics Symposium, Proceedings

PB - IEEE Computer Society Press

T2 - 2020 IEEE International Ultrasonics Symposium, IUS 2020

Y2 - 7 September 2020 through 11 September 2020

ER -

Quantitative microvessel analysis with 3-D super-resolution ultrasound and velocity mapping

Abstract

Publication series

Conference

Access to Document

Other files and links

Fingerprint

Cite this