King's College London

Research portal

Rapid homeostatic turnover of embryonic ECM during tissue morphogenesis

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)33-42.e9
JournalDevelopmental Cell
Volume54
Issue number1
Early online date24 Jun 2020
DOIs
Publication statusPublished - 6 Jul 2020

Documents

King's Authors

Abstract

The extracellular matrix (ECM) is hypothesized to form a long-lived cellular scaffold. Using modeling and in vivo pulse-chase experiments, Matsubayashi, Sánchez-Sánchez et al. show that the embryonic fruit fly ECM has a surprisingly short half-life. This labile ECM network is likely necessary to maintain plasticity for growth and morphogenesis.

Download statistics

No data available

View graph of relations

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454