Research output: Contribution to journal › Article › peer-review
Yutaka Matsubayashi, Besaiz Sánchez Sánchez, Stefania Marcotti, Eduardo Serna Morales, Anca Dragu, María-del-Carmen Díaz-de-la-Loza, Gema Vizcay-Barrena, Roland Fleck, Brian Stramer
| Original language | English |
|---|---|
| Pages (from-to) | 33-42.e9 |
| Journal | Developmental Cell |
| Volume | 54 |
| Issue number | 1 |
| Early online date | 24 Jun 2020 |
| DOIs | |
| Accepted/In press | 2 Jun 2020 |
| E-pub ahead of print | 24 Jun 2020 |
| Published | 6 Jul 2020 |
| Additional links |
Rapid homeostatic turnover of_MATSUBAYASHI_Accepted2June2020_GOLD VoR
1_s2.0_S153458072030455X_main.pdf, 3.3 MB, application/pdf
Uploaded date:21 Aug 2020
Version:Final published version
Licence:CC BY
The extracellular matrix (ECM) is hypothesized to form a long-lived cellular scaffold. Using modeling and in vivo pulse-chase experiments, Matsubayashi, Sánchez-Sánchez et al. show that the embryonic fruit fly ECM has a surprisingly short half-life. This labile ECM network is likely necessary to maintain plasticity for growth and morphogenesis.
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