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Reawakening of ancestral dental potential as a mechanism to explain dental pathologies

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Reawakening of ancestral dental potential as a mechanism to explain dental pathologies. / hovorakova, Maria; Zahradnicek, Oldrich; Bartos, Martin; Hurnik, Pavel; Stransky, Jiri; Stembírek, J; Tucker, Abigail.

In: INTEGRATIVE AND COMPARATIVE BIOLOGY, 16.03.2020.

Research output: Contribution to journalReview article

Harvard

hovorakova, M, Zahradnicek, O, Bartos, M, Hurnik, P, Stransky, J, Stembírek, J & Tucker, A 2020, 'Reawakening of ancestral dental potential as a mechanism to explain dental pathologies', INTEGRATIVE AND COMPARATIVE BIOLOGY.

APA

hovorakova, M., Zahradnicek, O., Bartos, M., Hurnik, P., Stransky, J., Stembírek, J., & Tucker, A. (Accepted/In press). Reawakening of ancestral dental potential as a mechanism to explain dental pathologies. INTEGRATIVE AND COMPARATIVE BIOLOGY, [ICB-2020-0001.R1].

Vancouver

hovorakova M, Zahradnicek O, Bartos M, Hurnik P, Stransky J, Stembírek J et al. Reawakening of ancestral dental potential as a mechanism to explain dental pathologies. INTEGRATIVE AND COMPARATIVE BIOLOGY. 2020 Mar 16. ICB-2020-0001.R1.

Author

hovorakova, Maria ; Zahradnicek, Oldrich ; Bartos, Martin ; Hurnik, Pavel ; Stransky, Jiri ; Stembírek, J ; Tucker, Abigail. / Reawakening of ancestral dental potential as a mechanism to explain dental pathologies. In: INTEGRATIVE AND COMPARATIVE BIOLOGY. 2020.

Bibtex Download

@article{d39eef01af494bd481e459fc0834b9a3,
title = "Reawakening of ancestral dental potential as a mechanism to explain dental pathologies",
abstract = "During evolution there has been a trend to reduce both the number of teeth and the location where they are found within the oral cavity. In mammals the formation of teeth is restricted to a horseshoe band of odontogenic tissue, creating a single dental arch on the top and bottom of the jaw. Additional teeth and structures containing dental tissue, such as odontogenic tumours or cysts, can appear as pathologies. These tooth-like structures can be associated with the normal dentition, appearing within the dental arch, or in non-dental areas. The aetiology of these pathologies is not well elucidated. Reawakening of the potential to form teeth in different parts of the oral cavity could explain the origin of dental pathologies outside the dental arch, thus such pathologies are a consequence of our evolutionary history. In this review we look at the changing pattern of tooth formation within the oral cavity during vertebrate evolution, the potential to form additional tooth-like structures in mammals, and discuss how this knowledge shapes our understanding of dental pathologies in humans.",
keywords = "Odontogenic potential, dental anomalies, Odontoma, tooth row, Shh, Pitx2",
author = "Maria hovorakova and Oldrich Zahradnicek and Martin Bartos and Pavel Hurnik and Jiri Stransky and J Stemb{\'i}rek and Abigail Tucker",
year = "2020",
month = mar,
day = "16",
language = "English",
journal = "INTEGRATIVE AND COMPARATIVE BIOLOGY",
issn = "1450-7063",
publisher = "Oxford University Press",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Reawakening of ancestral dental potential as a mechanism to explain dental pathologies

AU - hovorakova, Maria

AU - Zahradnicek, Oldrich

AU - Bartos, Martin

AU - Hurnik, Pavel

AU - Stransky, Jiri

AU - Stembírek, J

AU - Tucker, Abigail

PY - 2020/3/16

Y1 - 2020/3/16

N2 - During evolution there has been a trend to reduce both the number of teeth and the location where they are found within the oral cavity. In mammals the formation of teeth is restricted to a horseshoe band of odontogenic tissue, creating a single dental arch on the top and bottom of the jaw. Additional teeth and structures containing dental tissue, such as odontogenic tumours or cysts, can appear as pathologies. These tooth-like structures can be associated with the normal dentition, appearing within the dental arch, or in non-dental areas. The aetiology of these pathologies is not well elucidated. Reawakening of the potential to form teeth in different parts of the oral cavity could explain the origin of dental pathologies outside the dental arch, thus such pathologies are a consequence of our evolutionary history. In this review we look at the changing pattern of tooth formation within the oral cavity during vertebrate evolution, the potential to form additional tooth-like structures in mammals, and discuss how this knowledge shapes our understanding of dental pathologies in humans.

AB - During evolution there has been a trend to reduce both the number of teeth and the location where they are found within the oral cavity. In mammals the formation of teeth is restricted to a horseshoe band of odontogenic tissue, creating a single dental arch on the top and bottom of the jaw. Additional teeth and structures containing dental tissue, such as odontogenic tumours or cysts, can appear as pathologies. These tooth-like structures can be associated with the normal dentition, appearing within the dental arch, or in non-dental areas. The aetiology of these pathologies is not well elucidated. Reawakening of the potential to form teeth in different parts of the oral cavity could explain the origin of dental pathologies outside the dental arch, thus such pathologies are a consequence of our evolutionary history. In this review we look at the changing pattern of tooth formation within the oral cavity during vertebrate evolution, the potential to form additional tooth-like structures in mammals, and discuss how this knowledge shapes our understanding of dental pathologies in humans.

KW - Odontogenic potential, dental anomalies, Odontoma, tooth row, Shh, Pitx2

M3 - Review article

JO - INTEGRATIVE AND COMPARATIVE BIOLOGY

JF - INTEGRATIVE AND COMPARATIVE BIOLOGY

SN - 1450-7063

M1 - ICB-2020-0001.R1

ER -

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