Recent advances in recording electrophysiological data simultaneously with magnetic resonance imaging

TY - JOUR

T1 - Recent advances in recording electrophysiological data simultaneously with magnetic resonance imaging

AU - Laufs, H.

AU - Daunizeau, J.

AU - Carmichael, D. W.

AU - Kleinschmidt, A.

N1 - Funding Information: We thank Rachel Thornton for scientific input and helpful comments on the manuscript. HL receives funding from the Deutsche Forschungsgemeinschaft (LA 1452/3-1) and the Bundesministerium für Bildung und Forschung, JD from the Marie Curie Intra-European research fellowship programme, DWC from a grant from the Medical Research Council (MRC grant number G0301067), and AK from the Volkswagen Foundation and the Institut du Cerveau et de la Moelle epiniere.

PY - 2008/4/1

Y1 - 2008/4/1

N2 - Simultaneous recording of brain activity by different neurophysiological modalities can yield insights that reach beyond those obtained by each technique individually, even when compared to those from the post-hoc integration of results from each technique recorded sequentially. Success in the endeavour of real-time multimodal experiments requires special hardware and software as well as purpose-tailored experimental design and analysis strategies. Here, we review the key methodological issues in recording electrophysiological data in humans simultaneously with magnetic resonance imaging (MRI), focusing on recent technical and analytical advances in the field. Examples are derived from simultaneous electroencephalography (EEG) and electromyography (EMG) during functional MRI in cognitive and systems neuroscience as well as in clinical neurology, in particular in epilepsy and movement disorders. We conclude with an outlook on current and future efforts to achieve true integration of electrical and haemodynamic measures of neuronal activity using data fusion models.

AB - Simultaneous recording of brain activity by different neurophysiological modalities can yield insights that reach beyond those obtained by each technique individually, even when compared to those from the post-hoc integration of results from each technique recorded sequentially. Success in the endeavour of real-time multimodal experiments requires special hardware and software as well as purpose-tailored experimental design and analysis strategies. Here, we review the key methodological issues in recording electrophysiological data in humans simultaneously with magnetic resonance imaging (MRI), focusing on recent technical and analytical advances in the field. Examples are derived from simultaneous electroencephalography (EEG) and electromyography (EMG) during functional MRI in cognitive and systems neuroscience as well as in clinical neurology, in particular in epilepsy and movement disorders. We conclude with an outlook on current and future efforts to achieve true integration of electrical and haemodynamic measures of neuronal activity using data fusion models.

KW - EEG

KW - Electrophysiology

KW - EMG

KW - fMRI

KW - Fusion

KW - Human

KW - Magnetic resonance imaging

KW - Multimodal imaging

UR - http://www.scopus.com/inward/record.url?scp=40649090844&partnerID=8YFLogxK

U2 - 10.1016/j.neuroimage.2007.11.039

DO - 10.1016/j.neuroimage.2007.11.039

M3 - Review article

C2 - 18201910

AN - SCOPUS:40649090844

SN - 1053-8119

VL - 40

SP - 515

EP - 528

JO - NeuroImage

JF - NeuroImage

IS - 2

ER -