Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy

S J Till; M R Jacobson; F O'Brien; S R Durham; A KleinJan; W J Fokkens; S Juliusson; O Löwhagen

Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy

S J Till
, M R Jacobson
, F O'Brien
, S R Durham
, A KleinJan
, W J Fokkens
, S Juliusson
, O Löwhagen

King's College London

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

Local antigen presentation may be necessary for both primary and recall T-cell responses to grass pollen in hay fever patients. We examined the effect of seasonal allergen exposure on nasal mucosal antigen-presenting cell (APC) populations and the effects of topical corticosteroid therapy.

Original language	English
Pages (from-to)	126-31
Number of pages	6
Journal	Allergy
Volume	56
Issue number	2
Publication status	Published - Feb 2001

Keywords

Macrophages
Androstadienes
Cell Movement
Humans
Antigens, CD20
Biopsy
Pollen
Antigens, Differentiation, Myelomonocytic
Langerhans Cells
Rhinitis, Allergic, Seasonal
Poaceae
Antigens, CD
Adult
Nasal Mucosa
Antigens, CD1
Immunohistochemistry
Male
Administration, Topical
Female

Cite this

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title = "Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy",

abstract = "Local antigen presentation may be necessary for both primary and recall T-cell responses to grass pollen in hay fever patients. We examined the effect of seasonal allergen exposure on nasal mucosal antigen-presenting cell (APC) populations and the effects of topical corticosteroid therapy.",

keywords = "Macrophages, Androstadienes, Cell Movement, Humans, Antigens, CD20, Biopsy, Pollen, Antigens, Differentiation, Myelomonocytic, Langerhans Cells, Rhinitis, Allergic, Seasonal, Poaceae, Antigens, CD, Adult, Nasal Mucosa, Antigens, CD1, Immunohistochemistry, Male, Administration, Topical, Female",

author = "Till, \{S J\} and Jacobson, \{M R\} and F O'Brien and Durham, \{S R\} and A KleinJan and Fokkens, \{W J\} and S Juliusson and O L{\"o}whagen",

year = "2001",

month = feb,

language = "English",

volume = "56",

pages = "126--31",

journal = "Allergy",

issn = "0105-4538",

publisher = "Blackwell Publishing",

number = "2",

}

TY - JOUR

T1 - Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy

AU - Till, S J

AU - Jacobson, M R

AU - O'Brien, F

AU - Durham, S R

AU - KleinJan, A

AU - Fokkens, W J

AU - Juliusson, S

AU - Löwhagen, O

PY - 2001/2

Y1 - 2001/2

N2 - Local antigen presentation may be necessary for both primary and recall T-cell responses to grass pollen in hay fever patients. We examined the effect of seasonal allergen exposure on nasal mucosal antigen-presenting cell (APC) populations and the effects of topical corticosteroid therapy.

AB - Local antigen presentation may be necessary for both primary and recall T-cell responses to grass pollen in hay fever patients. We examined the effect of seasonal allergen exposure on nasal mucosal antigen-presenting cell (APC) populations and the effects of topical corticosteroid therapy.

KW - Macrophages

KW - Androstadienes

KW - Cell Movement

KW - Humans

KW - Antigens, CD20

KW - Biopsy

KW - Pollen

KW - Antigens, Differentiation, Myelomonocytic

KW - Langerhans Cells

KW - Rhinitis, Allergic, Seasonal

KW - Poaceae

KW - Antigens, CD

KW - Adult

KW - Nasal Mucosa

KW - Antigens, CD1

KW - Immunohistochemistry

KW - Male

KW - Administration, Topical

KW - Female

M3 - Article

C2 - 11167372

SN - 0105-4538

VL - 56

SP - 126

EP - 131

JO - Allergy

JF - Allergy

IS - 2

ER -

Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy

Abstract

Keywords

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