Abstract
Derived from a rat model, the theory of Sagvolden et al. offers air all-explanatory model of attention-deficit/hyperactivity disorder (ADHD) anatomy, behaviour, and cognition as being caused predominantly by a hypo-dopaminergic mesolimbic (affecting the mesocortical and nigrostriatal) system, leading to abnormal reward and extinction processes. This model suffers from oversimplification and reductionism, reflecting the limitations of the use of animal models to explain higher mental disorders
Original language | English |
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Pages (from-to) | 439 - + |
Number of pages | 2 |
Journal | Behavioral and Brain Sciences |
Volume | 28 |
Issue number | 3 |
Publication status | Published - Jun 2005 |