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Refining rodent models of spinal cord injury

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Refining rodent models of spinal cord injury. / Lilley, Elliot; Andrews, Melissa R.; Bradbury, Elizabeth J.; Elliott, Heather; Hawkins, Penny; Ichiyama, Ronaldo M.; Keeley, Jo; Michael-Titus, Adina T.; Moon, Lawrence D.F.; Pluchino, Stefano; Riddell, John; Ryder, Kathy; Yip, Ping K.

In: Experimental Neurology, Vol. 328, 113273, 06.2020.

Research output: Contribution to journalReview article

Harvard

Lilley, E, Andrews, MR, Bradbury, EJ, Elliott, H, Hawkins, P, Ichiyama, RM, Keeley, J, Michael-Titus, AT, Moon, LDF, Pluchino, S, Riddell, J, Ryder, K & Yip, PK 2020, 'Refining rodent models of spinal cord injury', Experimental Neurology, vol. 328, 113273. https://doi.org/10.1016/j.expneurol.2020.113273

APA

Lilley, E., Andrews, M. R., Bradbury, E. J., Elliott, H., Hawkins, P., Ichiyama, R. M., ... Yip, P. K. (2020). Refining rodent models of spinal cord injury. Experimental Neurology, 328, [113273]. https://doi.org/10.1016/j.expneurol.2020.113273

Vancouver

Lilley E, Andrews MR, Bradbury EJ, Elliott H, Hawkins P, Ichiyama RM et al. Refining rodent models of spinal cord injury. Experimental Neurology. 2020 Jun;328. 113273. https://doi.org/10.1016/j.expneurol.2020.113273

Author

Lilley, Elliot ; Andrews, Melissa R. ; Bradbury, Elizabeth J. ; Elliott, Heather ; Hawkins, Penny ; Ichiyama, Ronaldo M. ; Keeley, Jo ; Michael-Titus, Adina T. ; Moon, Lawrence D.F. ; Pluchino, Stefano ; Riddell, John ; Ryder, Kathy ; Yip, Ping K. / Refining rodent models of spinal cord injury. In: Experimental Neurology. 2020 ; Vol. 328.

Bibtex Download

@article{15ea273cdf154e9ab464276bcc5c1caf,
title = "Refining rodent models of spinal cord injury",
abstract = "This report was produced by an Expert Working Group (EWG) consisting of UK-based researchers, veterinarians and regulators of animal experiments with specialist knowledge of the use of animal models of spinal cord injury (SCI). It aims to facilitate the implementation of the Three Rs (Replacement, Reduction and Refinement), with an emphasis on refinement. Specific animal welfare issues were identified and discussed, and practical measures proposed, with the aim of reducing animal use and suffering, reducing experimental variability, and increasing translatability within this critically important research field.",
keywords = "Animal model, Animal welfare, Paralysis, Refinement, Regeneration, Spinal contusion, Spinal cord injury, Spinal transection, Three Rs, Tissue repair, Translational research",
author = "Elliot Lilley and Andrews, {Melissa R.} and Bradbury, {Elizabeth J.} and Heather Elliott and Penny Hawkins and Ichiyama, {Ronaldo M.} and Jo Keeley and Michael-Titus, {Adina T.} and Moon, {Lawrence D.F.} and Stefano Pluchino and John Riddell and Kathy Ryder and Yip, {Ping K.}",
year = "2020",
month = "6",
doi = "10.1016/j.expneurol.2020.113273",
language = "English",
volume = "328",
journal = "Experimental Neurology",
issn = "0014-4886",
publisher = "ACADEMIC PRESS INC",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Refining rodent models of spinal cord injury

AU - Lilley, Elliot

AU - Andrews, Melissa R.

AU - Bradbury, Elizabeth J.

AU - Elliott, Heather

AU - Hawkins, Penny

AU - Ichiyama, Ronaldo M.

AU - Keeley, Jo

AU - Michael-Titus, Adina T.

AU - Moon, Lawrence D.F.

AU - Pluchino, Stefano

AU - Riddell, John

AU - Ryder, Kathy

AU - Yip, Ping K.

PY - 2020/6

Y1 - 2020/6

N2 - This report was produced by an Expert Working Group (EWG) consisting of UK-based researchers, veterinarians and regulators of animal experiments with specialist knowledge of the use of animal models of spinal cord injury (SCI). It aims to facilitate the implementation of the Three Rs (Replacement, Reduction and Refinement), with an emphasis on refinement. Specific animal welfare issues were identified and discussed, and practical measures proposed, with the aim of reducing animal use and suffering, reducing experimental variability, and increasing translatability within this critically important research field.

AB - This report was produced by an Expert Working Group (EWG) consisting of UK-based researchers, veterinarians and regulators of animal experiments with specialist knowledge of the use of animal models of spinal cord injury (SCI). It aims to facilitate the implementation of the Three Rs (Replacement, Reduction and Refinement), with an emphasis on refinement. Specific animal welfare issues were identified and discussed, and practical measures proposed, with the aim of reducing animal use and suffering, reducing experimental variability, and increasing translatability within this critically important research field.

KW - Animal model

KW - Animal welfare

KW - Paralysis

KW - Refinement

KW - Regeneration

KW - Spinal contusion

KW - Spinal cord injury

KW - Spinal transection

KW - Three Rs

KW - Tissue repair

KW - Translational research

UR - http://www.scopus.com/inward/record.url?scp=85081197391&partnerID=8YFLogxK

U2 - 10.1016/j.expneurol.2020.113273

DO - 10.1016/j.expneurol.2020.113273

M3 - Review article

C2 - 32142803

AN - SCOPUS:85081197391

VL - 328

JO - Experimental Neurology

JF - Experimental Neurology

SN - 0014-4886

M1 - 113273

ER -

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