TY - JOUR
T1 - Reflections on the Opportunities and Challenges of applying Experience-Based Co-Design (EBCD) to Phase 1 Clinical Trials in Oncology
AU - Graber, Nils
AU - Canova, Nina
AU - Bryant-Lukosius, Denise
AU - Robert, Glenn
AU - Navarro-Rodrigo, Blanca
AU - Trueb, Lionel
AU - Coukos, George
AU - Eicher, Manuela
AU - Corbiere, Tourane
AU - Colomer-Lahiguera, Sara
PY - 2024/4/25
Y1 - 2024/4/25
N2 - Experience-Based Co-Design (EBCD) is a multi-stage participatory action research process which was developed originally to increase patient involvement in service improvement initiatives. We reflect on the opportunities and challenges of applying EBCD in a new context of early-phase clinical trials in oncology where experimental treatments are increasingly perceived as a therapeutic option and, in certain instances, their efficacy may lead to accelerated approval facilitating a swifter integration into standard care. We propose that the opportunity of applying EBCD in such trials lies in improving the delivery of patient-centered care, care coordination, and support during the transition from experimental to standard care. Three potential challenges when applying EBCD in early-phase clinical trials are discussed related to: the need for standardization in trial processes; planning EBCD in a context of high uncertainty; and vulnerability of patient populations. We reflect on potential solutions and argue that adopting co-design as an approach within early-phase clinical trials could enable improvements in the process of care simultaneously to the development of novel therapies.
AB - Experience-Based Co-Design (EBCD) is a multi-stage participatory action research process which was developed originally to increase patient involvement in service improvement initiatives. We reflect on the opportunities and challenges of applying EBCD in a new context of early-phase clinical trials in oncology where experimental treatments are increasingly perceived as a therapeutic option and, in certain instances, their efficacy may lead to accelerated approval facilitating a swifter integration into standard care. We propose that the opportunity of applying EBCD in such trials lies in improving the delivery of patient-centered care, care coordination, and support during the transition from experimental to standard care. Three potential challenges when applying EBCD in early-phase clinical trials are discussed related to: the need for standardization in trial processes; planning EBCD in a context of high uncertainty; and vulnerability of patient populations. We reflect on potential solutions and argue that adopting co-design as an approach within early-phase clinical trials could enable improvements in the process of care simultaneously to the development of novel therapies.
KW - Co-design
KW - Experience-based Co-design
KW - Clinical trials
KW - Oncology
M3 - Article
SN - 1369-6513
JO - Health expectations : an international journal of public participation in health care and health policy
JF - Health expectations : an international journal of public participation in health care and health policy
ER -