Registration of RCBV and ADC maps with structural and physiological MR images in glioma patients: Study and validation

A. Mang, O. Camara, G. Brasil-Caseiras, William Crum, J. A. Schnabel, T. M. Buzugl, J. Rees, J. Thornton, H. R. Jaeger, D. J. Hawkes

Research output: Chapter in Book/Report/Conference proceedingConference paper

Abstract

The main goal of this study is to use image registration techniques to combine functional and structural information from different MR-derived images (ADC and rCBV maps, contrast enhanced T1-weighted MR images) in patients diagnosed with brain gliomas. This is a particularly challenging registration problem due to the diverse image characteristics and to the inconsistency between structural and functional image features. Specific registration protocols have been designed, including the selection of critical parameters, for the alignment of the multi-modal information. In addition, we have developed a visual assessment protocol to evaluate the accuracy of registration results obtained with the proposed methods. Preliminary results suggest that misregistration errors are below the functional image resolutions, thus achieving sub-voxel accuracy.

Original languageEnglish
Title of host publication2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3
Place of PublicationNEW YORK
PublisherIEEE
Pages37-40
Number of pages4
ISBN (Print)978-1-4244-0671-5
Publication statusPublished - 2007
Event4th IEEE International Symposium on Biomedical Imaging - Macro to Nano - Arlington
Duration: 12 Apr 200715 Apr 2007

Conference

Conference4th IEEE International Symposium on Biomedical Imaging - Macro to Nano
CityArlington
Period12/04/200715/04/2007

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