TY - JOUR
T1 - Regression, developmental trajectory and associated problems in disorders in the autism spectrum
T2 - the SNAP study
AU - Baird, Gillian
AU - Charman, Tony
AU - Pickles, Andrew
AU - Chandler, Susie
AU - Loucas, Tom
AU - Meldrum, David
AU - Carcani-Rathwell, Iris
AU - Serkana, Devanitha
AU - Simonoff, Emily
PY - 2008/11
Y1 - 2008/11
N2 - We report rates of regression and associated findings in a population derived group of 255 children aged 9-14 years, participating in a prevalence study of autism spectrum disorders (ASD); 53 with narrowly defined autism, 105 with broader ASD and 97 with non-ASD neurodevelopmental problems, drawn from those with special educational needs within a population of 56,946 children. Language regression was reported in 30% with narrowly defined autism, 8% with broader ASD and less than 3% with developmental problems without ASD. A smaller group of children were identified who underwent a less clear setback. Regression was associated with higher rates of autistic symptoms and a deviation in developmental trajectory. Regression was not associated with epilepsy or gastrointestinal problems.
AB - We report rates of regression and associated findings in a population derived group of 255 children aged 9-14 years, participating in a prevalence study of autism spectrum disorders (ASD); 53 with narrowly defined autism, 105 with broader ASD and 97 with non-ASD neurodevelopmental problems, drawn from those with special educational needs within a population of 56,946 children. Language regression was reported in 30% with narrowly defined autism, 8% with broader ASD and less than 3% with developmental problems without ASD. A smaller group of children were identified who underwent a less clear setback. Regression was associated with higher rates of autistic symptoms and a deviation in developmental trajectory. Regression was not associated with epilepsy or gastrointestinal problems.
KW - Asperger Syndrome
KW - Autistic Disorder
KW - Child
KW - Child Development Disorders, Pervasive
KW - Humans
KW - Regression (Psychology)
U2 - 10.1007/s10803-008-0571-9
DO - 10.1007/s10803-008-0571-9
M3 - Article
C2 - 18449635
VL - 38
SP - 1827
EP - 1836
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 10
ER -