Regression, developmental trajectory and associated problems in disorders in the autism spectrum: the SNAP study

Gillian Baird, Tony Charman, Andrew Pickles, Susie Chandler, Tom Loucas, David Meldrum, Iris Carcani-Rathwell, Devanitha Serkana, Emily Simonoff

Research output: Contribution to journalArticlepeer-review

129 Citations (Scopus)

Abstract

We report rates of regression and associated findings in a population derived group of 255 children aged 9-14 years, participating in a prevalence study of autism spectrum disorders (ASD); 53 with narrowly defined autism, 105 with broader ASD and 97 with non-ASD neurodevelopmental problems, drawn from those with special educational needs within a population of 56,946 children. Language regression was reported in 30% with narrowly defined autism, 8% with broader ASD and less than 3% with developmental problems without ASD. A smaller group of children were identified who underwent a less clear setback. Regression was associated with higher rates of autistic symptoms and a deviation in developmental trajectory. Regression was not associated with epilepsy or gastrointestinal problems.
Original languageEnglish
Pages (from-to)1827 - 1836
Number of pages10
JournalJournal of Autism and Developmental Disorders
Volume38
Issue number10
DOIs
Publication statusPublished - Nov 2008

Keywords

  • Asperger Syndrome
  • Autistic Disorder
  • Child
  • Child Development Disorders, Pervasive
  • Humans
  • Regression (Psychology)

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