Renewable sorbent material for solid phase extraction with direct coupling of sequential injection analysis-bead injection to liquid chromatography-electrospray ionization tandem mass spectrometry

Warunya Boonjob; Hana Sklenářová; Leon Barron; Petr Solich; Norman Smith

doi:10.1007/s00216-015-8752-9

Renewable sorbent material for solid phase extraction with direct coupling of sequential injection analysis-bead injection to liquid chromatography-electrospray ionization tandem mass spectrometry

Warunya Boonjob^*, Hana Sklenářová, Leon Barron, Petr Solich, Norman Smith

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The use of small scale renewable sorbent material for automated solid phase extraction of multi-residue pharmaceuticals in environmental samples exploiting the sequential injection analysis-bead injection with direct coupling to liquid chromatography-electrospray ionization tandem mass spectrometry (SIA-BI-μSPE-LC-ESI-MS/MS) is presented to determine beta-blockers, namely atenolol, sotalol, pindolol, acebutolol, timolol, metoprolol, labetalol, carazolol, propranolol and betaxolol. These compounds yielded the same product ions, therefore were affected in terms of quantification when flow injection analysis-mass spectrometry (FIA-MS) was used. Thus, analytes and matrix present in the sample travel together into the ionization source which can seriously affect the ionization efficiency and analyte signals due to monitoring over a short time period. [Figure not available: see fulltext.]

Original language	English
Pages (from-to)	5719-5728
Number of pages	10
Journal	ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume	407
Issue number	19
DOIs	https://doi.org/10.1007/s00216-015-8752-9
Publication status	Published - 14 May 2015

Keywords

Drug monitoring/drug screening
Sequential injection analysis
Solid phase extraction (SPE)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00216-015-8752-9

Cite this

Boonjob, W., Sklenářová, H., Barron, L., Solich, P., & Smith, N. (2015). Renewable sorbent material for solid phase extraction with direct coupling of sequential injection analysis-bead injection to liquid chromatography-electrospray ionization tandem mass spectrometry. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 407(19), 5719-5728. https://doi.org/10.1007/s00216-015-8752-9

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title = "Renewable sorbent material for solid phase extraction with direct coupling of sequential injection analysis-bead injection to liquid chromatography-electrospray ionization tandem mass spectrometry",

abstract = "The use of small scale renewable sorbent material for automated solid phase extraction of multi-residue pharmaceuticals in environmental samples exploiting the sequential injection analysis-bead injection with direct coupling to liquid chromatography-electrospray ionization tandem mass spectrometry (SIA-BI-μSPE-LC-ESI-MS/MS) is presented to determine beta-blockers, namely atenolol, sotalol, pindolol, acebutolol, timolol, metoprolol, labetalol, carazolol, propranolol and betaxolol. These compounds yielded the same product ions, therefore were affected in terms of quantification when flow injection analysis-mass spectrometry (FIA-MS) was used. Thus, analytes and matrix present in the sample travel together into the ionization source which can seriously affect the ionization efficiency and analyte signals due to monitoring over a short time period. [Figure not available: see fulltext.]",

keywords = "Drug monitoring/drug screening, Sequential injection analysis, Solid phase extraction (SPE)",

author = "Warunya Boonjob and Hana Sklen{\'a}{\v r}ov{\'a} and Leon Barron and Petr Solich and Norman Smith",

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language = "English",

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Boonjob, W, Sklenářová, H, Barron, L, Solich, P & Smith, N 2015, 'Renewable sorbent material for solid phase extraction with direct coupling of sequential injection analysis-bead injection to liquid chromatography-electrospray ionization tandem mass spectrometry', ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 407, no. 19, pp. 5719-5728. https://doi.org/10.1007/s00216-015-8752-9

Renewable sorbent material for solid phase extraction with direct coupling of sequential injection analysis-bead injection to liquid chromatography-electrospray ionization tandem mass spectrometry. / Boonjob, Warunya; Sklenářová, Hana; Barron, Leon et al.
In: ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 407, No. 19, 14.05.2015, p. 5719-5728.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Renewable sorbent material for solid phase extraction with direct coupling of sequential injection analysis-bead injection to liquid chromatography-electrospray ionization tandem mass spectrometry

AU - Boonjob, Warunya

AU - Sklenářová, Hana

AU - Barron, Leon

AU - Solich, Petr

AU - Smith, Norman

PY - 2015/5/14

Y1 - 2015/5/14

N2 - The use of small scale renewable sorbent material for automated solid phase extraction of multi-residue pharmaceuticals in environmental samples exploiting the sequential injection analysis-bead injection with direct coupling to liquid chromatography-electrospray ionization tandem mass spectrometry (SIA-BI-μSPE-LC-ESI-MS/MS) is presented to determine beta-blockers, namely atenolol, sotalol, pindolol, acebutolol, timolol, metoprolol, labetalol, carazolol, propranolol and betaxolol. These compounds yielded the same product ions, therefore were affected in terms of quantification when flow injection analysis-mass spectrometry (FIA-MS) was used. Thus, analytes and matrix present in the sample travel together into the ionization source which can seriously affect the ionization efficiency and analyte signals due to monitoring over a short time period. [Figure not available: see fulltext.]

AB - The use of small scale renewable sorbent material for automated solid phase extraction of multi-residue pharmaceuticals in environmental samples exploiting the sequential injection analysis-bead injection with direct coupling to liquid chromatography-electrospray ionization tandem mass spectrometry (SIA-BI-μSPE-LC-ESI-MS/MS) is presented to determine beta-blockers, namely atenolol, sotalol, pindolol, acebutolol, timolol, metoprolol, labetalol, carazolol, propranolol and betaxolol. These compounds yielded the same product ions, therefore were affected in terms of quantification when flow injection analysis-mass spectrometry (FIA-MS) was used. Thus, analytes and matrix present in the sample travel together into the ionization source which can seriously affect the ionization efficiency and analyte signals due to monitoring over a short time period. [Figure not available: see fulltext.]

KW - Drug monitoring/drug screening

KW - Sequential injection analysis

KW - Solid phase extraction (SPE)

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U2 - 10.1007/s00216-015-8752-9

DO - 10.1007/s00216-015-8752-9

M3 - Article

SN - 1618-2642

VL - 407

SP - 5719

EP - 5728

JO - ANALYTICAL AND BIOANALYTICAL CHEMISTRY

JF - ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IS - 19

ER -

Renewable sorbent material for solid phase extraction with direct coupling of sequential injection analysis-bead injection to liquid chromatography-electrospray ionization tandem mass spectrometry

Abstract

Keywords

UN SDGs

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