Reproducibility of twitch and sniff transdiaphragmatic pressures

Y M Luo, N Hart, N Mustfa, W D C Man, G F Rafferty, M I Polkey, J Moxham

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

Twitch transdiaphragmatic pressure (Tw Pdi) measured with magnetic stimulation of the phrenic nerve is used to follow up patients and to assess the effect of clinical treatments on diaphragm function. However the reproducibility of Tw Pdi on different occasions has been little studied. We investigated 32 normal subjects, measuring Tw Pdi elicited by bilateral magnetic stimulation of the phrenic nerves on two to 14 occasions. Sniff transdiaphragmatic pressure (sniff Pdi) was also measured. The mean value of Tw Pdi and sniff Pdi were 28 +/- 5 and 134 +/- 24 cm H2O, respectively. The within subjects coefficient of variation was 11% for both Tw Pdi and sniff Pdi. We conclude that there is a variability of Tw Pdi and the variability of Tw Pdi is the same as that of sniff Pdi. (C) 2002 Elsevier Science B.V. All rights reserved.
Original languageEnglish
Pages (from-to)301 - 306
Number of pages6
JournalRESPIRATORY PHYSIOLOGY AND NEUROBIOLOGY
Volume132
Issue number3
DOIs
Publication statusPublished - 4 Sept 2002

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