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Reprogramming towards Endothelial Cells for Vascular Regeneration

Research output: Contribution to journalArticle

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Reprogramming towards Endothelial Cells for Vascular Regeneration. / Hong, Xuechong; Le Bras, Alexandra; Margariti, Andriana; Xu, Qingbo.

In: Genes & Diseases, 27.02.2016.

Research output: Contribution to journalArticle

Harvard

Hong, X, Le Bras, A, Margariti, A & Xu, Q 2016, 'Reprogramming towards Endothelial Cells for Vascular Regeneration', Genes & Diseases. https://doi.org/10.1016/j.gendis.2016.02.003

APA

Hong, X., Le Bras, A., Margariti, A., & Xu, Q. (2016). Reprogramming towards Endothelial Cells for Vascular Regeneration. Genes & Diseases. https://doi.org/10.1016/j.gendis.2016.02.003

Vancouver

Hong X, Le Bras A, Margariti A, Xu Q. Reprogramming towards Endothelial Cells for Vascular Regeneration. Genes & Diseases. 2016 Feb 27. https://doi.org/10.1016/j.gendis.2016.02.003

Author

Hong, Xuechong ; Le Bras, Alexandra ; Margariti, Andriana ; Xu, Qingbo. / Reprogramming towards Endothelial Cells for Vascular Regeneration. In: Genes & Diseases. 2016.

Bibtex Download

@article{bb51de17cb3840e6978a5b0ac4898329,
title = "Reprogramming towards Endothelial Cells for Vascular Regeneration",
abstract = "Abstract Endothelial damage and dysfunction are implicated in cardiovascular pathological changes and the development of vascular diseases. In view of the fact that the spontaneous endothelial cell (EC) regeneration is a slow and insufficient process, it would be of great significance to explore alternative cell sources capable of generating functional ECs to repair damaged endothelium. Indeed, recent achievements of cell reprogramming to convert somatic cells to other cell types provide new powerful approaches to study endothelial regeneration. Based on progress in the research field, the present review aims to explore the strategies and mechanisms of generating endothelial cells through reprogramming from somatic cells, and to examine what this means for the potential application of cell therapy in the clinic.",
keywords = "Stem cells, cell reprogramming, endothelial cells, iPS cells, endothelial regeneration, atherosclerosis",
author = "Xuechong Hong and {Le Bras}, Alexandra and Andriana Margariti and Qingbo Xu",
year = "2016",
month = feb,
day = "27",
doi = "10.1016/j.gendis.2016.02.003",
language = "English",
journal = "Genes & Diseases",
issn = "2352-3042",
publisher = "Elsevier BV",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Reprogramming towards Endothelial Cells for Vascular Regeneration

AU - Hong, Xuechong

AU - Le Bras, Alexandra

AU - Margariti, Andriana

AU - Xu, Qingbo

PY - 2016/2/27

Y1 - 2016/2/27

N2 - Abstract Endothelial damage and dysfunction are implicated in cardiovascular pathological changes and the development of vascular diseases. In view of the fact that the spontaneous endothelial cell (EC) regeneration is a slow and insufficient process, it would be of great significance to explore alternative cell sources capable of generating functional ECs to repair damaged endothelium. Indeed, recent achievements of cell reprogramming to convert somatic cells to other cell types provide new powerful approaches to study endothelial regeneration. Based on progress in the research field, the present review aims to explore the strategies and mechanisms of generating endothelial cells through reprogramming from somatic cells, and to examine what this means for the potential application of cell therapy in the clinic.

AB - Abstract Endothelial damage and dysfunction are implicated in cardiovascular pathological changes and the development of vascular diseases. In view of the fact that the spontaneous endothelial cell (EC) regeneration is a slow and insufficient process, it would be of great significance to explore alternative cell sources capable of generating functional ECs to repair damaged endothelium. Indeed, recent achievements of cell reprogramming to convert somatic cells to other cell types provide new powerful approaches to study endothelial regeneration. Based on progress in the research field, the present review aims to explore the strategies and mechanisms of generating endothelial cells through reprogramming from somatic cells, and to examine what this means for the potential application of cell therapy in the clinic.

KW - Stem cells

KW - cell reprogramming

KW - endothelial cells

KW - iPS cells

KW - endothelial regeneration

KW - atherosclerosis

U2 - 10.1016/j.gendis.2016.02.003

DO - 10.1016/j.gendis.2016.02.003

M3 - Article

JO - Genes & Diseases

JF - Genes & Diseases

SN - 2352-3042

ER -

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