Research activity and the association with mortality

Baris A Ozdemir; Alan Karthikesalingam; Sidhartha Sinha; Jan D Poloniecki; Robert J Hinchliffe; Matt M Thompson; Jonathan D Gower; Annette Boaz; Peter JE Holt

doi:10.1371/journal.pone.0118253

Research activity and the association with mortality

Baris A Ozdemir, Alan Karthikesalingam, Sidhartha Sinha, Jan D Poloniecki, Robert J Hinchliffe, Matt M Thompson, Jonathan D Gower, Annette Boaz, Peter JE Holt

Policy Institute at King's

Research output: Contribution to journal › Article › peer-review

156 Citations (Scopus)

Abstract

INTRODUCTION: The aims of this study were to describe the key features of acute NHS Trusts with different levels of research activity and to investigate associations between research activity and clinical outcomes. METHODS: National Institute for Health Research (NIHR) Comprehensive Clinical Research Network (CCRN) funding and number of patients recruited to NIHR Clinical Research Network (CRN) portfolio studies for each NHS Trusts were used as markers of research activity. Patient-level data for adult non-elective admissions were extracted from the English Hospital Episode Statistics (2005-10). Risk-adjusted mortality associations between Trust structures, research activity and, clinical outcomes were investigated. RESULTS: Low mortality Trusts received greater levels of funding and recruited more patients adjusted for size of Trust (n = 35, 2,349 pounds/bed [95,855-2,843], 5.9 patients/bed [2.7-9.0]) than Trusts with expected (n = 63, 1,110 pounds/bed, [864-1,357] p

Original language	English
Pages (from-to)	e0118253-
Journal	PloS one
Volume	10
Issue number	2
DOIs	https://doi.org/10.1371/journal.pone.0118253
Publication status	Published - 1 Feb 2015

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10.1371/journal.pone.0118253Licence: CC BY

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title = "Research activity and the association with mortality",

abstract = "INTRODUCTION: The aims of this study were to describe the key features of acute NHS Trusts with different levels of research activity and to investigate associations between research activity and clinical outcomes. METHODS: National Institute for Health Research (NIHR) Comprehensive Clinical Research Network (CCRN) funding and number of patients recruited to NIHR Clinical Research Network (CRN) portfolio studies for each NHS Trusts were used as markers of research activity. Patient-level data for adult non-elective admissions were extracted from the English Hospital Episode Statistics (2005-10). Risk-adjusted mortality associations between Trust structures, research activity and, clinical outcomes were investigated. RESULTS: Low mortality Trusts received greater levels of funding and recruited more patients adjusted for size of Trust (n = 35, 2,349 pounds/bed [95,855-2,843], 5.9 patients/bed [2.7-9.0]) than Trusts with expected (n = 63, 1,110 pounds/bed, [864-1,357] p",

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AU - Ozdemir, Baris A

AU - Karthikesalingam, Alan

AU - Sinha, Sidhartha

AU - Poloniecki, Jan D

AU - Hinchliffe, Robert J

AU - Thompson, Matt M

AU - Gower, Jonathan D

AU - Boaz, Annette

AU - Holt, Peter JE

PY - 2015/2/1

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N2 - INTRODUCTION: The aims of this study were to describe the key features of acute NHS Trusts with different levels of research activity and to investigate associations between research activity and clinical outcomes. METHODS: National Institute for Health Research (NIHR) Comprehensive Clinical Research Network (CCRN) funding and number of patients recruited to NIHR Clinical Research Network (CRN) portfolio studies for each NHS Trusts were used as markers of research activity. Patient-level data for adult non-elective admissions were extracted from the English Hospital Episode Statistics (2005-10). Risk-adjusted mortality associations between Trust structures, research activity and, clinical outcomes were investigated. RESULTS: Low mortality Trusts received greater levels of funding and recruited more patients adjusted for size of Trust (n = 35, 2,349 pounds/bed [95,855-2,843], 5.9 patients/bed [2.7-9.0]) than Trusts with expected (n = 63, 1,110 pounds/bed, [864-1,357] p

AB - INTRODUCTION: The aims of this study were to describe the key features of acute NHS Trusts with different levels of research activity and to investigate associations between research activity and clinical outcomes. METHODS: National Institute for Health Research (NIHR) Comprehensive Clinical Research Network (CCRN) funding and number of patients recruited to NIHR Clinical Research Network (CRN) portfolio studies for each NHS Trusts were used as markers of research activity. Patient-level data for adult non-elective admissions were extracted from the English Hospital Episode Statistics (2005-10). Risk-adjusted mortality associations between Trust structures, research activity and, clinical outcomes were investigated. RESULTS: Low mortality Trusts received greater levels of funding and recruited more patients adjusted for size of Trust (n = 35, 2,349 pounds/bed [95,855-2,843], 5.9 patients/bed [2.7-9.0]) than Trusts with expected (n = 63, 1,110 pounds/bed, [864-1,357] p

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JF - PloS one

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Research activity and the association with mortality

Abstract

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