Research Waste in Atopic Eczema Trials—Just the Tip of the Iceberg

Carsten Flohr; Stephan Weidinger

doi:10.1016/j.jid.2016.06.614

Research Waste in Atopic Eczema Trials—Just the Tip of the Iceberg

Carsten Flohr^*, Stephan Weidinger

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Comment/debate › peer-review

7 Citations (Scopus)

Abstract

Clinical trials often continue to be undertaken even though the effectiveness of the intervention under consideration has already been demonstrated. In addition, vehicle- or placebo-controlled studies predominate over head-to-head comparisons, although the latter would be more informative for clinicians in guiding patient management. This creates research waste, and both investigators and funders are to blame. Wilkes et al. used a network analysis approach to show duplication of effort in trials assessing topical calcineurin inhibitors and corticosteroids as treatment options for atopic eczema. Unfortunately, this is just the tip of the research waste iceberg.

Original language	English
Pages (from-to)	1930-1933
Number of pages	4
Journal	Journal of Investigative Dermatology
Volume	136
Issue number	10
DOIs	https://doi.org/10.1016/j.jid.2016.06.614
Publication status	Published - 1 Oct 2016

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abstract = "Clinical trials often continue to be undertaken even though the effectiveness of the intervention under consideration has already been demonstrated. In addition, vehicle- or placebo-controlled studies predominate over head-to-head comparisons, although the latter would be more informative for clinicians in guiding patient management. This creates research waste, and both investigators and funders are to blame. Wilkes et al. used a network analysis approach to show duplication of effort in trials assessing topical calcineurin inhibitors and corticosteroids as treatment options for atopic eczema. Unfortunately, this is just the tip of the research waste iceberg.",

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AB - Clinical trials often continue to be undertaken even though the effectiveness of the intervention under consideration has already been demonstrated. In addition, vehicle- or placebo-controlled studies predominate over head-to-head comparisons, although the latter would be more informative for clinicians in guiding patient management. This creates research waste, and both investigators and funders are to blame. Wilkes et al. used a network analysis approach to show duplication of effort in trials assessing topical calcineurin inhibitors and corticosteroids as treatment options for atopic eczema. Unfortunately, this is just the tip of the research waste iceberg.

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Research Waste in Atopic Eczema Trials—Just the Tip of the Iceberg

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