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Resveratrol: A Potential Hippocampal Plasticity Enhancer

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Resveratrol: A Potential Hippocampal Plasticity Enhancer. / Dias, Gisele Pereira; Cocks, Graham; Do Nascimento Bevilaqua, Mário Cesar; Nardi, Antonio Egidio; Thuret, Sandrine.

In: Oxidative Medicine and Cellular Longevity, Vol. 2016, 9651236, 2016.

Research output: Contribution to journalArticle

Harvard

Dias, GP, Cocks, G, Do Nascimento Bevilaqua, MC, Nardi, AE & Thuret, S 2016, 'Resveratrol: A Potential Hippocampal Plasticity Enhancer', Oxidative Medicine and Cellular Longevity, vol. 2016, 9651236. https://doi.org/10.1155/2016/9651236

APA

Dias, G. P., Cocks, G., Do Nascimento Bevilaqua, M. C., Nardi, A. E., & Thuret, S. (2016). Resveratrol: A Potential Hippocampal Plasticity Enhancer. Oxidative Medicine and Cellular Longevity, 2016, [9651236]. https://doi.org/10.1155/2016/9651236

Vancouver

Dias GP, Cocks G, Do Nascimento Bevilaqua MC, Nardi AE, Thuret S. Resveratrol: A Potential Hippocampal Plasticity Enhancer. Oxidative Medicine and Cellular Longevity. 2016;2016. 9651236. https://doi.org/10.1155/2016/9651236

Author

Dias, Gisele Pereira ; Cocks, Graham ; Do Nascimento Bevilaqua, Mário Cesar ; Nardi, Antonio Egidio ; Thuret, Sandrine. / Resveratrol: A Potential Hippocampal Plasticity Enhancer. In: Oxidative Medicine and Cellular Longevity. 2016 ; Vol. 2016.

Bibtex Download

@article{c445be5e797f472bb01dcdec60c29c9e,
title = "Resveratrol: A Potential Hippocampal Plasticity Enhancer",
abstract = "The search for molecules capable of restoring altered hippocampal plasticity in psychiatric and neurological conditions is one of the most important tasks of modern neuroscience. It is well established that neural plasticity, such as the ability of the postnatal hippocampus to continuously generate newly functional neurons throughout life, a process called adult hippocampal neurogenesis (AHN), can be modulated not only by pharmacological agents, physical exercise, and environmental enrichment, but also by {"}nutraceutical{"} agents. In this review we focus on resveratrol, a phenol and phytoalexin found in the skin of grapes and red berries, as well as in nuts. Resveratrol has been reported to have antioxidant and antitumor properties, but its effects as a neural plasticity inducer are still debated. The current review examines recent evidence implicating resveratrol in regulating hippocampal neural plasticity and in mitigating the effects of various disorders and diseases on this important brain structure. Overall, findings show that resveratrol can improve cognition and mood and enhance hippocampal plasticity and AHN; however, some studies report opposite effects, with resveratrol inhibiting aspects of AHN. Therefore, further investigation is needed to resolve these controversies before resveratrol can be established as a safe coadjuvant in preventing and treating neuropsychiatric conditions.",
author = "Dias, {Gisele Pereira} and Graham Cocks and {Do Nascimento Bevilaqua}, {M{\'a}rio Cesar} and Nardi, {Antonio Egidio} and Sandrine Thuret",
year = "2016",
doi = "10.1155/2016/9651236",
language = "English",
volume = "2016",
journal = "Oxidative Medicine and Cellular Longevity",
issn = "1942-0900",
publisher = "Hindawi Publishing Corporation",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Resveratrol: A Potential Hippocampal Plasticity Enhancer

AU - Dias, Gisele Pereira

AU - Cocks, Graham

AU - Do Nascimento Bevilaqua, Mário Cesar

AU - Nardi, Antonio Egidio

AU - Thuret, Sandrine

PY - 2016

Y1 - 2016

N2 - The search for molecules capable of restoring altered hippocampal plasticity in psychiatric and neurological conditions is one of the most important tasks of modern neuroscience. It is well established that neural plasticity, such as the ability of the postnatal hippocampus to continuously generate newly functional neurons throughout life, a process called adult hippocampal neurogenesis (AHN), can be modulated not only by pharmacological agents, physical exercise, and environmental enrichment, but also by "nutraceutical" agents. In this review we focus on resveratrol, a phenol and phytoalexin found in the skin of grapes and red berries, as well as in nuts. Resveratrol has been reported to have antioxidant and antitumor properties, but its effects as a neural plasticity inducer are still debated. The current review examines recent evidence implicating resveratrol in regulating hippocampal neural plasticity and in mitigating the effects of various disorders and diseases on this important brain structure. Overall, findings show that resveratrol can improve cognition and mood and enhance hippocampal plasticity and AHN; however, some studies report opposite effects, with resveratrol inhibiting aspects of AHN. Therefore, further investigation is needed to resolve these controversies before resveratrol can be established as a safe coadjuvant in preventing and treating neuropsychiatric conditions.

AB - The search for molecules capable of restoring altered hippocampal plasticity in psychiatric and neurological conditions is one of the most important tasks of modern neuroscience. It is well established that neural plasticity, such as the ability of the postnatal hippocampus to continuously generate newly functional neurons throughout life, a process called adult hippocampal neurogenesis (AHN), can be modulated not only by pharmacological agents, physical exercise, and environmental enrichment, but also by "nutraceutical" agents. In this review we focus on resveratrol, a phenol and phytoalexin found in the skin of grapes and red berries, as well as in nuts. Resveratrol has been reported to have antioxidant and antitumor properties, but its effects as a neural plasticity inducer are still debated. The current review examines recent evidence implicating resveratrol in regulating hippocampal neural plasticity and in mitigating the effects of various disorders and diseases on this important brain structure. Overall, findings show that resveratrol can improve cognition and mood and enhance hippocampal plasticity and AHN; however, some studies report opposite effects, with resveratrol inhibiting aspects of AHN. Therefore, further investigation is needed to resolve these controversies before resveratrol can be established as a safe coadjuvant in preventing and treating neuropsychiatric conditions.

UR - http://www.scopus.com/inward/record.url?scp=84975159130&partnerID=8YFLogxK

U2 - 10.1155/2016/9651236

DO - 10.1155/2016/9651236

M3 - Article

AN - SCOPUS:84975159130

VL - 2016

JO - Oxidative Medicine and Cellular Longevity

JF - Oxidative Medicine and Cellular Longevity

SN - 1942-0900

M1 - 9651236

ER -

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