TY - JOUR
T1 - Retinoid and TGF-beta Families: Crosstalk in Development, Neoplasia, Immunity, and Tissue Repair
AU - Xu, Qihe
AU - Kopp, Jeffrey B.
PY - 2012/5
Y1 - 2012/5
N2 - Transforming growth factor-beta (TGF-beta) isoforms are profibrotic cytokines, par excellence, and have complex multifunctional effects on many systems, depending on the biologic setting. Retinoids are vitamin A derivatives that also have diverse effects in development, physiology, and disease. The interactions between these classes of molecules are, not surprisingly, highly complex and are dependent on the tissue, cellular, and molecular settings. Semin Nephrol 32:287-294 (C) 2012 Elsevier Inc. All rights reserved.
AB - Transforming growth factor-beta (TGF-beta) isoforms are profibrotic cytokines, par excellence, and have complex multifunctional effects on many systems, depending on the biologic setting. Retinoids are vitamin A derivatives that also have diverse effects in development, physiology, and disease. The interactions between these classes of molecules are, not surprisingly, highly complex and are dependent on the tissue, cellular, and molecular settings. Semin Nephrol 32:287-294 (C) 2012 Elsevier Inc. All rights reserved.
U2 - 10.1016/j.semnephrol.2012.04.008
DO - 10.1016/j.semnephrol.2012.04.008
M3 - Literature review
SN - 0270-9295
VL - 32
SP - 287
EP - 294
JO - Seminars in Nephrology
JF - Seminars in Nephrology
IS - 3
ER -