Rhinovirus infection and healthcare utilisation in prematurely born infants

Simon B Drysdale, Mireia Alcazar-Paris, Theresa Wilson, Melvyn Smith, Mark Zuckerman, Simon Broughton, Gerrard F Rafferty, Janet L Peacock, Sebastian L Johnston, Anne Greenough

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)

Abstract

Do rhinovirus lower respiratory tract infections (RV) LRTIs in prematurely born infants increase health related cost of care during infancy? Patients and methods: 153 infants born <36 weeks of gestation were prospectively followed to one year. Cost of care was calculated from the NHS reference costing scheme and health care utilisation determined by examining hospital/general practitioner records.

Twenty infants developed RV LRTIs (RV group), 17 RSV LRTIs (RSV group), 12 both RV and RSV LRTIs (RV/RSV group), 74 had no LRTI (no LRTI group). Compared to the no LRTI group, the RV/RSV LRTI group had the greatest increase in adjusted mean cost (difference=£5769), followed by the RV LRTI group (difference=£278), then the RSV LRTI group (difference=£172), p=0.045. The RV group had more out-patient (p<0.05) and respiratory related general practitioner (p<0.05) attendances and more wheezed at follow up (p<0.001) than the no LRTI group and more respiratory related out-patient attendances than the RSV LRTI group (p<0.05). Answer to the question: RV LRTIs were associated with increased health related cost of care during infancy; our results suggest that the RV compared to the RSV group suffered greater chronic respiratory morbidity.
Original languageEnglish
Pages (from-to)1029-1036
Number of pages8
JournalEuropean Respiratory Journal
Volume42
Issue number4
DOIs
Publication statusPublished - 1 Oct 2013

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