Rho GTPases and cell cycle control

P Villalonga; A J Ridley

doi:10.1080/08977190600560651

Rho GTPases and cell cycle control

P Villalonga, A J Ridley

Research output: Contribution to journal › Literature review › peer-review

82 Citations (Scopus)

Abstract

Members of the Rho family of small GTPases are crucial regulators of biological responses in eukaryotic cells, including cytoskeletal dynamics, cell motility and cell cycle progression. In the present review, we summarize our current understanding of the role of Rho proteins in cell cycle control, highlighting the contribution of specific members of the Rho family and their downstream targets to the regulation of key elements from the core cell cycle machinery, mostly involved in the G1/S transition

Original language	English
Pages (from-to)	159 - 164
Number of pages	6
Journal	Growth Factors
Volume	24
Issue number	3
DOIs	https://doi.org/10.1080/08977190600560651
Publication status	Published - Sept 2006

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10.1080/08977190600560651

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title = "Rho GTPases and cell cycle control",

abstract = "Members of the Rho family of small GTPases are crucial regulators of biological responses in eukaryotic cells, including cytoskeletal dynamics, cell motility and cell cycle progression. In the present review, we summarize our current understanding of the role of Rho proteins in cell cycle control, highlighting the contribution of specific members of the Rho family and their downstream targets to the regulation of key elements from the core cell cycle machinery, mostly involved in the G1/S transition",

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AU - Villalonga, P

AU - Ridley, A J

PY - 2006/9

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N2 - Members of the Rho family of small GTPases are crucial regulators of biological responses in eukaryotic cells, including cytoskeletal dynamics, cell motility and cell cycle progression. In the present review, we summarize our current understanding of the role of Rho proteins in cell cycle control, highlighting the contribution of specific members of the Rho family and their downstream targets to the regulation of key elements from the core cell cycle machinery, mostly involved in the G1/S transition

AB - Members of the Rho family of small GTPases are crucial regulators of biological responses in eukaryotic cells, including cytoskeletal dynamics, cell motility and cell cycle progression. In the present review, we summarize our current understanding of the role of Rho proteins in cell cycle control, highlighting the contribution of specific members of the Rho family and their downstream targets to the regulation of key elements from the core cell cycle machinery, mostly involved in the G1/S transition

U2 - 10.1080/08977190600560651

DO - 10.1080/08977190600560651

M3 - Literature review

VL - 24

SP - 159

EP - 164

JO - Growth Factors

JF - Growth Factors

IS - 3

ER -

Rho GTPases and cell cycle control

Abstract

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