TY - JOUR
T1 - Risk factors for the development of bronchopulmonary dysplasia
T2 - the role of antenatal infection and inflammation
AU - Lall, Abhimanu
AU - Prendergast, Michael
AU - Greenough, Anne
PY - 2007/10
Y1 - 2007/10
N2 - Bronchopulmonary dysplasia, chronic oxygen dependency, is a common adverse outcome of very premature birth. It has important implications for health resource utilization, since affected children require frequent readmissions to hospital in the first 2 years after birth and, even as adolescents, have lung function abnormalities and troublesome respiratory symptoms. The current population of very prematurely born infants may develop chronic oxygen dependency in the absence of severe, acute respiratory distress, so-called 'new' bronchopulmonary dysplasia. This appears to be the result of impaired antenatal lung growth; antenatal infection and inflammation make the premature infant's lungs more vulnerable to injury.
AB - Bronchopulmonary dysplasia, chronic oxygen dependency, is a common adverse outcome of very premature birth. It has important implications for health resource utilization, since affected children require frequent readmissions to hospital in the first 2 years after birth and, even as adolescents, have lung function abnormalities and troublesome respiratory symptoms. The current population of very prematurely born infants may develop chronic oxygen dependency in the absence of severe, acute respiratory distress, so-called 'new' bronchopulmonary dysplasia. This appears to be the result of impaired antenatal lung growth; antenatal infection and inflammation make the premature infant's lungs more vulnerable to injury.
U2 - 10.1586/17476348.1.2.247
DO - 10.1586/17476348.1.2.247
M3 - Article
C2 - 20477188
SN - 1747-6356
VL - 1
SP - 247
EP - 254
JO - Expert review of respiratory medicine
JF - Expert review of respiratory medicine
IS - 2
M1 - N/A
ER -