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Risk of Hospitalization in Patients with Alzheimer's Disease and Lewy Body Dementia: Time to and Length of Stay

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Risk of Hospitalization in Patients with Alzheimer's Disease and Lewy Body Dementia : Time to and Length of Stay. / Østerhus, Ragnhild; Dalen, Ingvild; Bergland, Anne Katrine; Aarsland, Dag; Kjosavik, Svein R.

In: Journal of Alzheimer's Disease, Vol. 74, No. 4, 01.01.2020, p. 1221-1230.

Research output: Contribution to journalArticle

Harvard

Østerhus, R, Dalen, I, Bergland, AK, Aarsland, D & Kjosavik, SR 2020, 'Risk of Hospitalization in Patients with Alzheimer's Disease and Lewy Body Dementia: Time to and Length of Stay', Journal of Alzheimer's Disease, vol. 74, no. 4, pp. 1221-1230. https://doi.org/10.3233/JAD-191141

APA

Østerhus, R., Dalen, I., Bergland, A. K., Aarsland, D., & Kjosavik, S. R. (2020). Risk of Hospitalization in Patients with Alzheimer's Disease and Lewy Body Dementia: Time to and Length of Stay. Journal of Alzheimer's Disease, 74(4), 1221-1230. https://doi.org/10.3233/JAD-191141

Vancouver

Østerhus R, Dalen I, Bergland AK, Aarsland D, Kjosavik SR. Risk of Hospitalization in Patients with Alzheimer's Disease and Lewy Body Dementia: Time to and Length of Stay. Journal of Alzheimer's Disease. 2020 Jan 1;74(4):1221-1230. https://doi.org/10.3233/JAD-191141

Author

Østerhus, Ragnhild ; Dalen, Ingvild ; Bergland, Anne Katrine ; Aarsland, Dag ; Kjosavik, Svein R. / Risk of Hospitalization in Patients with Alzheimer's Disease and Lewy Body Dementia : Time to and Length of Stay. In: Journal of Alzheimer's Disease. 2020 ; Vol. 74, No. 4. pp. 1221-1230.

Bibtex Download

@article{ac98d3adb80b4937818fa3e2931a8101,
title = "Risk of Hospitalization in Patients with Alzheimer's Disease and Lewy Body Dementia: Time to and Length of Stay",
abstract = "Background: Patients with dementia are at high risk of being hospitalized, but there is little knowledge whether this applies to all forms of dementia. Objective: To investigate if there are differences in hospitalization between patients with Alzheimer's disease (AD) and Lewy body dementia (LBD), and further, to compare admission rate with the general age-matched population. Methods: Patients (age 75.7±7.4) recently diagnosed with mild form of AD (n=110) or LBD (n=91) were included from outpatient clinics. The participants were followed from time of diagnosis, for five years or until death. Study outcomes were time to first hospitalization after diagnosis, number of admissions, total number of hospital days, and length of stay. Age-standardized admission ratios were calculated. Time to first admission was analyzed using competing risks regression models, and differences in number of hospitalizations and hospital days were addressed using negative binomial regression models. Results: More than 77% of the patients were admitted, largely as unplanned hospitalizations. Patients with LBD had significantly shorter time until first hospitalization (median 1.28 years, 95% CI 0.93-1.67 versus AD: 2.32 years, 95% CI 1.74-3.31) and more days in hospital (median 13 days, IQR 4, 38), than patients with AD (7 days, IQR 0, 18). Conclusion: Our data indicates that patients with LBD have shorter time until first admission and higher admission rate than AD patients. This imposes a great burden on patients, their family, and the health care system. More knowledge about hospital admissions of people with dementia is needed. Future studies should investigate strategies to avoid potentially preventable admissions.",
keywords = "Alzheimer's disease, dementia, hospitalization, length of stay, Lewy body dementia, patient admission",
author = "Ragnhild {\O}sterhus and Ingvild Dalen and Bergland, {Anne Katrine} and Dag Aarsland and Kjosavik, {Svein R.}",
year = "2020",
month = jan,
day = "1",
doi = "10.3233/JAD-191141",
language = "English",
volume = "74",
pages = "1221--1230",
journal = "JOURNAL OF ALZHEIMERS DISEASE",
issn = "1387-2877",
number = "4",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Risk of Hospitalization in Patients with Alzheimer's Disease and Lewy Body Dementia

T2 - Time to and Length of Stay

AU - Østerhus, Ragnhild

AU - Dalen, Ingvild

AU - Bergland, Anne Katrine

AU - Aarsland, Dag

AU - Kjosavik, Svein R.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Background: Patients with dementia are at high risk of being hospitalized, but there is little knowledge whether this applies to all forms of dementia. Objective: To investigate if there are differences in hospitalization between patients with Alzheimer's disease (AD) and Lewy body dementia (LBD), and further, to compare admission rate with the general age-matched population. Methods: Patients (age 75.7±7.4) recently diagnosed with mild form of AD (n=110) or LBD (n=91) were included from outpatient clinics. The participants were followed from time of diagnosis, for five years or until death. Study outcomes were time to first hospitalization after diagnosis, number of admissions, total number of hospital days, and length of stay. Age-standardized admission ratios were calculated. Time to first admission was analyzed using competing risks regression models, and differences in number of hospitalizations and hospital days were addressed using negative binomial regression models. Results: More than 77% of the patients were admitted, largely as unplanned hospitalizations. Patients with LBD had significantly shorter time until first hospitalization (median 1.28 years, 95% CI 0.93-1.67 versus AD: 2.32 years, 95% CI 1.74-3.31) and more days in hospital (median 13 days, IQR 4, 38), than patients with AD (7 days, IQR 0, 18). Conclusion: Our data indicates that patients with LBD have shorter time until first admission and higher admission rate than AD patients. This imposes a great burden on patients, their family, and the health care system. More knowledge about hospital admissions of people with dementia is needed. Future studies should investigate strategies to avoid potentially preventable admissions.

AB - Background: Patients with dementia are at high risk of being hospitalized, but there is little knowledge whether this applies to all forms of dementia. Objective: To investigate if there are differences in hospitalization between patients with Alzheimer's disease (AD) and Lewy body dementia (LBD), and further, to compare admission rate with the general age-matched population. Methods: Patients (age 75.7±7.4) recently diagnosed with mild form of AD (n=110) or LBD (n=91) were included from outpatient clinics. The participants were followed from time of diagnosis, for five years or until death. Study outcomes were time to first hospitalization after diagnosis, number of admissions, total number of hospital days, and length of stay. Age-standardized admission ratios were calculated. Time to first admission was analyzed using competing risks regression models, and differences in number of hospitalizations and hospital days were addressed using negative binomial regression models. Results: More than 77% of the patients were admitted, largely as unplanned hospitalizations. Patients with LBD had significantly shorter time until first hospitalization (median 1.28 years, 95% CI 0.93-1.67 versus AD: 2.32 years, 95% CI 1.74-3.31) and more days in hospital (median 13 days, IQR 4, 38), than patients with AD (7 days, IQR 0, 18). Conclusion: Our data indicates that patients with LBD have shorter time until first admission and higher admission rate than AD patients. This imposes a great burden on patients, their family, and the health care system. More knowledge about hospital admissions of people with dementia is needed. Future studies should investigate strategies to avoid potentially preventable admissions.

KW - Alzheimer's disease

KW - dementia

KW - hospitalization

KW - length of stay

KW - Lewy body dementia

KW - patient admission

UR - http://www.scopus.com/inward/record.url?scp=85083897560&partnerID=8YFLogxK

U2 - 10.3233/JAD-191141

DO - 10.3233/JAD-191141

M3 - Article

C2 - 32144990

AN - SCOPUS:85083897560

VL - 74

SP - 1221

EP - 1230

JO - JOURNAL OF ALZHEIMERS DISEASE

JF - JOURNAL OF ALZHEIMERS DISEASE

SN - 1387-2877

IS - 4

ER -

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