Safe application of mitomycin C within the nasal cavity

T. Gutierrez*, C. Hopkins

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)


    Objective: To describe a novel technique of delivering mitomycin C safely via endoscopic sinus surgery.

    Case report: Mitomycin C was applied in the median frontal drainage pathway of a 44-year-old woman suffering from recalcitrant chronic frontal sinusitis. The mitomycin C was soaked onto a neurosurgical patty, which was delivered through a nasopharyngeal tube trimmed to ensure delivery directly to the desired area, thus sparing adjacent mucosa.

    Conclusions: Mitomycin C has been suggested to have a useful role in reducing post-operative scarring after endonasal surgery. The long term safety of topical mitomycin C is not yet known, and inadvertent topical application to adjacent mucosa should be avoided. The described technique achieves this in a simple manner, and can be easily applied to other locations.

    Original languageEnglish
    Pages (from-to)309-310
    Number of pages2
    JournalJournal of Laryngology and Otology
    Issue number3
    Publication statusPublished - Mar 2011


    • Frontal Sinus
    • Mitomycin C
    • Endoscopic Surgery
    • Complications


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