Saliva Cotinine as an Indicator of Cigarette Smoking in Adolescents

A. D. McNEILL*, M. J. JARVIS, R. WEST, M. A.H. RUSSELL, A. BRYANT

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

78 Citations (Scopus)

Abstract

Saliva cotinine and expired‐air carbon monoxide (CO) concentrations were measured in 508 girls aged 11–16 years attending an inner London comprehensive school. A saliva cotinine cut‐point of 14.7 ng/ml detected 99% of regular daily smokers and performed better than expired‐air CO (cut‐point 7 ppm) in identifying smoking (69% versus 54%). The mean saliva cotinine among the regular daily smokers was 200.8 ng/ml, and comparisons with adult smokers suggested that these adolescents were inhaling a similar dose of nicotine per cigarette. Within our sample no evidence was found for an increase in smoke inhalation per cigarette with increasing age suggesting that inhalation develops early in the smoking career.

Original languageEnglish
Pages (from-to)1355-1360
Number of pages6
JournalBritish Journal of Addiction
Volume82
Issue number12
DOIs
Publication statusPublished - Dec 1987

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