Sclerotherapy treatment of a large venous malformation invading the bladder wall related to Klippel-Trenaunay syndrome

Luke Foster; Narayan Karunanithy; Ramesh Thurairaja

doi:10.1136/bcr-2019-229823

Sclerotherapy treatment of a large venous malformation invading the bladder wall related to Klippel-Trenaunay syndrome

Luke Foster^*, Narayan Karunanithy, Ramesh Thurairaja

^*Corresponding author for this work

Biomedical Engineering & Imaging Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We report the case of a 35-year-old woman who presented with recurrent macroscopic haematuria and known diagnosis of Klippel-Trenaunay syndrome. Imaging and cystoscopy identified an extensive venous malformation involving a large area of the bladder wall. Holmium laser therapy was ineffective at obtaining symptom control. Following a multidisciplinary team meeting, transvenous sclerotherapy with sodium tetradecyl sulphate was performed under image guidance. A reduction in venous density was observed on cystoscopy and the patient has had complete resolution of symptoms within 6 weeks and continued to be asymptomatic up to 24-month follow-up. We propose that transvenous sclerotherapy is considered first-line treatment in this clinical setting.

Original language	English
Article number	e229823
Journal	BMJ case reports
Volume	13
Issue number	12
DOIs	https://doi.org/10.1136/bcr-2019-229823
Publication status	Published - 21 Dec 2020

Keywords

hematuria
interventional radiology
urological surgery
urology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1136/bcr-2019-229823

Cite this

@article{deb8fc4cb2a64a6a9c04a59e8160bf2c,

title = "Sclerotherapy treatment of a large venous malformation invading the bladder wall related to Klippel-Trenaunay syndrome",

abstract = "We report the case of a 35-year-old woman who presented with recurrent macroscopic haematuria and known diagnosis of Klippel-Trenaunay syndrome. Imaging and cystoscopy identified an extensive venous malformation involving a large area of the bladder wall. Holmium laser therapy was ineffective at obtaining symptom control. Following a multidisciplinary team meeting, transvenous sclerotherapy with sodium tetradecyl sulphate was performed under image guidance. A reduction in venous density was observed on cystoscopy and the patient has had complete resolution of symptoms within 6 weeks and continued to be asymptomatic up to 24-month follow-up. We propose that transvenous sclerotherapy is considered first-line treatment in this clinical setting. ",

keywords = "hematuria, interventional radiology, urological surgery, urology",

author = "Luke Foster and Narayan Karunanithy and Ramesh Thurairaja",

year = "2020",

month = dec,

day = "21",

doi = "10.1136/bcr-2019-229823",

language = "English",

volume = "13",

journal = "BMJ case reports",

issn = "1757-790X",

publisher = "BMJ Publishing Group",

number = "12",

}

TY - JOUR

T1 - Sclerotherapy treatment of a large venous malformation invading the bladder wall related to Klippel-Trenaunay syndrome

AU - Foster, Luke

AU - Karunanithy, Narayan

AU - Thurairaja, Ramesh

PY - 2020/12/21

Y1 - 2020/12/21

N2 - We report the case of a 35-year-old woman who presented with recurrent macroscopic haematuria and known diagnosis of Klippel-Trenaunay syndrome. Imaging and cystoscopy identified an extensive venous malformation involving a large area of the bladder wall. Holmium laser therapy was ineffective at obtaining symptom control. Following a multidisciplinary team meeting, transvenous sclerotherapy with sodium tetradecyl sulphate was performed under image guidance. A reduction in venous density was observed on cystoscopy and the patient has had complete resolution of symptoms within 6 weeks and continued to be asymptomatic up to 24-month follow-up. We propose that transvenous sclerotherapy is considered first-line treatment in this clinical setting.

AB - We report the case of a 35-year-old woman who presented with recurrent macroscopic haematuria and known diagnosis of Klippel-Trenaunay syndrome. Imaging and cystoscopy identified an extensive venous malformation involving a large area of the bladder wall. Holmium laser therapy was ineffective at obtaining symptom control. Following a multidisciplinary team meeting, transvenous sclerotherapy with sodium tetradecyl sulphate was performed under image guidance. A reduction in venous density was observed on cystoscopy and the patient has had complete resolution of symptoms within 6 weeks and continued to be asymptomatic up to 24-month follow-up. We propose that transvenous sclerotherapy is considered first-line treatment in this clinical setting.

KW - hematuria

KW - interventional radiology

KW - urological surgery

KW - urology

UR - http://www.scopus.com/inward/record.url?scp=85098219200&partnerID=8YFLogxK

U2 - 10.1136/bcr-2019-229823

DO - 10.1136/bcr-2019-229823

M3 - Article

C2 - 33370935

AN - SCOPUS:85098219200

SN - 1757-790X

VL - 13

JO - BMJ case reports

JF - BMJ case reports

IS - 12

M1 - e229823

ER -

Sclerotherapy treatment of a large venous malformation invading the bladder wall related to Klippel-Trenaunay syndrome

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this