Screening for stratification in two-phase (‘two- stage’) epidemiological surveys

Andrew Pickles; Graham Dunn; José Luis Vázquez-Barquero

doi:10.1177/096228029500400106

Screening for stratification in two-phase (‘two- stage’) epidemiological surveys

Andrew Pickles^*, Graham Dunn, José Luis Vázquez-Barquero

^*Corresponding author for this work

King's College London
Molecular Genetics Unit, Hospital Universitario Marqués de Valdecilla and Instituto de Formación e Investigación Marques de Valdecilla (IFIMAV), Av. Cardenal Herrera Oria s/n, Santander, Spain.

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Screening is undertaken not only for the purpose of giving therapeutic treatment to those among screen positive subjects found to be diagnosis positive, but it is also used in epidemiology as the first phase of multi-phase sampling designs. We review the use of such designs in epidemiology, and in psychiatric epidemiology in particular, focusing on two-phase or double sampling. We then compare a variety of approaches to the statistical analysis of data from such designs including the use of sampling weights, Gibbs sampling, full maximum likelihood for random effects logistic regression and a simple E-M algorithm for incomplete data. The methods are illustrated using data from a recent multi-phase study of psychiatric morbidity in northern Spain.

Original language	English
Pages (from-to)	73-89
Number of pages	17
Journal	Statistical Methods in Medical Research
Volume	4
Issue number	1
DOIs	https://doi.org/10.1177/096228029500400106
Publication status	Accepted/In press - 3 Jul 2018

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Screening for stratification in two-phase (‘two- stage’) epidemiological surveys

Abstract

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