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Research Outputs

  1. 2021
  2. Placental and endothelial biomarkers for the prediction of superimposed pre-eclampsia in chronic kidney disease

    Wiles, K., Bramham, K., Seed, P. T., Brockbank, A., Nelson-Piercy, C., Karumanchi, S. A., Lightstone, L. & Chappell, L. C., Jun 2021, In: Pregnancy Hypertension. 24, p. 58-64 7 p.

    Research output: Contribution to journalArticlepeer-review

  3. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

    Ovadia, C., Sajous, J., Seed, P. T., Patel, K., Williamson, N. J., Attilakos, G., Azzaroli, F., Bacq, Y., Batsry, L., Broom, K., Brun-Furrer, R., Bull, L., Chambers, J., Cui, Y., Ding, M., Dixon, P. H., Estiú, M. C., Gardiner, F. W., Geenes, V., Grymowicz, M. & 30 others, Günaydin, B., Hague, W. M., Haslinger, C., Hu, Y., Indraccolo, U., Juusela, A., Kane, S. C., Kebapcilar, A., Kebapcilar, L., Kohari, K., Kondrackienė, J., Koster, M. P. H., Lee, R. H., Liu, X., Locatelli, A., Macias, R. I. R., Madazli, R., Majewska, A., Maksym, K., Marathe, J. A., Morton, A., Oudijk, M. A., Öztekin, D., Peek, M. J., Shennan, A. H., Tribe, R. M., Tripodi, V., Vasavan, T., Chappell, L. C. & Williamson, C., 26 Apr 2021, In: The Lancet Gastroenterology & Hepatology.

    Research output: Contribution to journalArticlepeer-review

  4. Experiences of maternity care among women at increased risk of preterm birth receiving midwifery continuity of care compared to women receiving standard care: Results from the POPPIE pilot trial

    POPPIE Collaborative Group, 21 Apr 2021, In: PLoS ONE. 16, 4 April, p. e0248588 21 p., e0248588.

    Research output: Contribution to journalArticlepeer-review

  5. Brain volumetry in fetuses that deliver very preterm: An MRI pilot study

    Story, L., Davidson, A., Patkee, P., Fleiss, B., Kyriakopoulou, V., Colford, K., Sankaran, S., Seed, P., Jones, A., Hutter, J., Shennan, A. & Rutherford, M., 29 Mar 2021, In: NeuroImage: Clinical. 30, p. 102650 102650.

    Research output: Contribution to journalArticlepeer-review

  6. Prognostic indicators of severe disease in late preterm pre-eclampsia to guide decision making on timing of delivery: The PEACOCK study

    Duhig, K. E., Seed, P. T., Placzek, A., Sparkes, J., Hendy, E., Gill, C., Brockbank, A., Shennan, A. H., Thangaratinam, S. & Chappell, L. C., Jun 2021, In: Pregnancy Hypertension. 24, p. 90-95 6 p.

    Research output: Contribution to journalArticlepeer-review

  7. Adiposity and cardiovascular outcomes in three-year-old children of participants in UPBEAT, an RCT of a complex intervention in pregnant women with obesity

    on behalf of the UPBEAT consortium, Mar 2021, In: Pediatric Obesity. 16, 3, e12725.

    Research output: Contribution to journalArticlepeer-review

  8. Placental growth factor measurements in the assessment of women with suspected Preeclampsia: A stratified analysis of the PARROT trial

    Duhig, K. E., Myers, J. E., Gale, C., Girling, J. C., Harding, K., Sharp, A., Simpson, N. A. B., Tuffnell, D., Seed, P. T., Shennan, A. H. & Chappell, L. C., Mar 2021, In: Pregnancy Hypertension. 23, p. 41-47 7 p.

    Research output: Contribution to journalArticlepeer-review

  9. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: an individual participant data meta-analysis

    Ovadia, C., Sajous, J., Seed, P. T., Patel, K., Williamson, N. J., Attilakos, G., Azzaroli, F., Bacq, Y., Batsry, L., Broom, K., Brun-Furrer, R., Bull, L., Chambers, J., Cui, Y., Ding, M., Dixon, P., Estiu, M., Gardiner, F., Geenes, V., Grymowicz, M. & 37 others, Gunaydin, B., Hague, W., Haslinger, C., Hu, Y., Indraccolo, U., Juusela, A., Kane, S., Kebapcilar, A., Kebapcilar, L., Kohari, K., Kondrackiene, J., Koster, M., Lee, R., Liu, X., Locatelli, A., Macias, R., Madazli, R., Majewska, A., Maksym, K., Marathe, J., Morton, A., Oudijk, M., Oztekin, D., Peek, M., Shennan, A., Tribe, R., Tripodi, V., Turk Ozterlemez, N., Vasavan, T., Wong, L. F. A., Yinon, Y., Zhang, Q., Zloto, K., Marschall, H-U., Thornton, J., Chappell, L. & Williamson, C., 22 Feb 2021, (Accepted/In press) In: The Lancet Gastroenterology & Hepatology. p. 1-25 25 p.

    Research output: Contribution to journalArticlepeer-review

  10. Re-evaluating diagnostic thresholds for intrahepatic cholestasis of pregnancy: case-control and cohort study

    Mitchell, A. L., Ovadia, C., Syngelaki, A., Souretis, K., Martineau, M., Girling, J., Vasavan, T., Fan, H. M., Seed, P. T., Chambers, J., Walters, J. R. F., Nicolaides, K. & Williamson, C., 15 Feb 2021, In: BJOG.

    Research output: Contribution to journalArticlepeer-review

  11. Re-evaluating diagnostic thresholds for intrahepatic cholestasis of pregnancy: case-control and cohort study

    Mitchell, A., Ovadia, C., Syngelaki, A., Souretis, K., Martineau, M. G., Girling, J., Vasavan, T., Fan, C., Seed, P. T., Chambers, J., Walters, J. R. F., Nicolaides, K. H. & Williamson, C., 12 Feb 2021, (Accepted/In press) In: British Journal of Obstetrics and Gynaecology.

    Research output: Contribution to journalArticlepeer-review

  12. The effect of smoking on COVID-19 severity: a systematic review and meta-analysis

    Reddy, R. K., Charles, W. N., Sklavounos, A., Dutt, A., Seed, P. T. & Khajuria, A., Feb 2021, In: Journal of Medical Virology. 93, 2, p. 1045-1056 12 p.

    Research output: Contribution to journalArticlepeer-review

  13. Placental magnetic resonance imaging in chronic hypertension: A case-control study

    Ho, A., Hutter, J., Slator, P., Jackson, L., Seed, P. T., Mccabe, L., Al-Adnani, M., Marnerides, A., George, S., Story, L., Hajnal, J. V., Rutherford, M. & Chappell, L. C., 15 Jan 2021, In: Placenta. 104, p. 138-145 8 p.

    Research output: Contribution to journalArticlepeer-review

  14. The DNA methylation signatures in cord blood of neonates associated with birthweight are enriched for dmCpGs associated with maternal hypertension and folate intake

    Antoun, E., Titcombe, P., Dalrymple, K., Flynn, A. C., Poston, L., White, S., Seed, P. T., Inskip, H. M., Hanson, M. A., Cooper, C., Kitaba, N. T., Barton, S. J., Garratt, E. S., Murray, R., Godfrey, K. M. & Lillycrop, K. A., 2021, (Accepted/In press) In: Epigenetics.

    Research output: Contribution to journalArticlepeer-review

  15. 2020
  16. The impact of chronic kidney disease Stages 3-5 on pregnancy outcomes

    Wiles, K., Webster, P., Seed, P. T., Bennett-Richards, K., Bramham, K., Brunskill, N., Carr, S., Hall, M., Khan, R., Nelson-Piercy, C., Webster, L. M., Chappell, L. C. & Lightstone, L., 12 Dec 2020, In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 10 p.

    Research output: Contribution to journalArticlepeer-review

  17. Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations

    Vasavan, T., Deepak, S., Jayawardane, I. A., Lucchini, M., Martin, C., Geenes, V., Yang, J., Lövgren-Sandblom, A., Seed, P. T., Chambers, J., Stone, S., Kurlak, L., Dixon, P. H., Marschall, H-U., Gorelik, J., Chappell, L., Loughna, P., Thornton, J., Pipkin, F. B., Hayes-Gill, B. & 2 others, Fifer, W. P. & Williamson, C., 1 Dec 2020, In: Journal of Hepatology. 0, 0, p. 1-10

    Research output: Contribution to journalArticlepeer-review

  18. Placental growth factor for the prognosis of women with preeclampsia (fullPIERS model extension): context matters

    fullPIERS Group, 1 Dec 2020, In: BMC Pregnancy and Childbirth. 20, 1, p. 668 1 p., 668.

    Research output: Contribution to journalArticlepeer-review

  19. Maternal dysglycaemia, changes in the infant’s epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial

    UPBEAT Consortium, 5 Nov 2020, In: PLoS Medicine. 17, 11, 29 p., e1003229.

    Research output: Contribution to journalArticlepeer-review

  20. External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis

    IPPIC Collaborative Network, 2 Nov 2020, In: BMC Medicine. 18, 1, p. 302 1 p.

    Research output: Contribution to journalArticlepeer-review

  21. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a secondary analysis of the PITCHES trial

    Fleminger, J., Seed, P. T., Smith, A., Juszczak, E., Dixon, P. H., Chambers, J., Dorling, J., Williamson, C., Thornton, J. G. & Chappell, L., 16 Oct 2020, In: BJOG.

    Research output: Contribution to journalArticlepeer-review

  22. Midwifery continuity of care versus standard maternity care for women at increased risk of preterm birth: A hybrid implementation–effectiveness, randomised controlled pilot trial in the UK

    Fernandez Turienzo, C., Bick, D., Briley, A., Bollard, M., Coxon, K., Cross, P., Silverio, S. A., Singh, C., Seed, P., Tribe, R., Shennan, A., Sandall, J. & on behalf of the POPPIE Pilot Collaborative Group, 6 Oct 2020, In: PLoS Medicine. 17, 10, e1003350.

    Research output: Contribution to journalArticlepeer-review

  23. Quantitative fetal fibronectin for prediction of preterm birth in asymptomatic twin pregnancy

    Kuhrt, K., Hezelgrave-Elliott, N., Stock, S. J., Tribe, R., Seed, P. T. & Shennan, A. H., 1 Sep 2020, In: Acta Obstetricia et Gynecologica Scandinavica. 99, 9, p. 1191-1197 7 p.

    Research output: Contribution to journalArticlepeer-review

  24. Antenatal thymus volumes in fetuses that delivered <32 weeks gestation: an MRI pilot study

    Story, L., Zhang, T., Uus, A., Hutter, J., Egloff, A., Gibbons, D., Alison, H., Al-Adnani, M., Knight, C. L., Theodoulou, I., Deprez, M., Seed, P. T., Tribe, R. M., Shennan, A. H. & Rutherford, M., 31 Aug 2020, In: Acta Obstetricia et Gynecologica Scandinavica. 0, 0, p. 1-11

    Research output: Contribution to journalArticlepeer-review

  25. Impact of smoking on coronavirus disease 19 severity

    Reddy, R. K., Charles, W. N., Sklavounos, A., Seed, P. T. & Khajuria, A., 25 Aug 2020, In: Journal of Medical Virology. p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

  26. Incidence and characteristics of pregnancy-related death across ten low and middle-income geographical regions: secondary analysis of a cluster randomised controlled trial

    CRADLE Trial Collaborative Group, 1 Aug 2020, In: BJOG. 127, 9, p. 1082-1089 8 p.

    Research output: Contribution to journalArticlepeer-review

  27. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 2 Jul 2020, In: HYPERTENSION IN PREGNANCY. 39, 3, p. 326-335 10 p.

    Research output: Contribution to journalArticlepeer-review

  28. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In: Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticlepeer-review

  29. Lifestyle information and commercial weight management groups to support maternal postnatal weight management and positive lifestyle behaviour: the SWAN feasibility randomised controlled trial

    Bick, D., Taylor, C., Bhavnani, V., Healey, A., Seed, P., Roberts, S., Zasada, M., Avery, A., Craig, V., Khazaezadah, N., McMullen, S., O'Connor, S., Oki, B., Ntim, E. O., Poston, L. & Ussher, M., 30 Apr 2020, In: BJOG. 127, 5, p. 636-645 10 p.

    Research output: Contribution to journalArticlepeer-review

  30. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In: Thorax. 2019-213796.

    Research output: Contribution to journalArticlepeer-review

  31. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In: Trials. 21, 1, p. 347 347.

    Research output: Contribution to journalArticlepeer-review

  32. Metabolic phenotyping by treatment modality in obese women with gestational diabetes suggests diverse pathophysiology: an exploratory study

    UPBEAT Consortium, 18 Mar 2020, (Accepted/In press) In: PLOS One.

    Research output: Contribution to journalArticlepeer-review

  33. MAVRIC: A Multicentre Randomised Controlled Trial of Transabdominal Versus Transvaginal Cervical Cerclage

    Shennan, A., Chandiramani, M., Bennett, P., David, A. L., Girling, J., Ridout, A., Seed, P. T., Simpson, N., Thornton, S., Tydeman, G., Quenby, S. & Carter, J., 1 Mar 2020, In: American Journal of Obstetrics and Gynecology. 222, 3, p. 261.e1-261.e9

    Research output: Contribution to journalArticlepeer-review

  34. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In: Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  35. 2019
  36. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

    Borges Manna, L., Ovadia, C., Lövgren-Sandblom, A., Chambers, J., Begum, S., Seed, P., Walker, I., Chappell, L. C., Marschall, H-U. & Williamson, C., 1 Dec 2019, In: BJOG. 126, 13, p. 1633-1640 8 p.

    Research output: Contribution to journalArticlepeer-review

  37. Pregnancy-related Acute Kidney Injury in pre-eclampsia: risk factors and renal outcomes

    Conti-Ramsden, F. I., Nathan, H. L., De Greeff, A., Hall, D. R., Seed, P. T., Chappell, L. C., Shennan, A. H. & Bramham, K., 1 Nov 2019, In: Hypertension. 74, 5, p. 1144–1151 8 p.

    Research output: Contribution to journalArticlepeer-review

  38. Protocol for a two-arm feasibility RCT to support postnatal maternal weight management and positive lifestyle behaviour in women from an ethnically diverse inner city population: The SWAN feasibility trial

    Bick, D., Taylor, C., Avery, A., Bhavnani, V., Craig, V., Healey, A., Khazaezadeh, N., McMullen, S., Oki, B., Oteng-Ntim, E., O'Connor, S., Poston, L., Seed, P., Roberts, S. & Ussher, M., 23 Oct 2019, In: Pilot and Feasibility Studies. 5, 1, 117.

    Research output: Contribution to journalArticlepeer-review

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