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Research Outputs

  1. 2022
  2. Planned delivery or expectant management in pre-eclampsia: an individual participant data meta-analysis

    Beardmore-Gray, A., Seed, P. T., Fleminger, J., Zwertbroek, E., Bernardes, T., Mol, B. W., Battersby, C., Koopmans, C., Broekhuijsen, K., Boers, K., Owens, M. Y., Thornton, J., Green, M., Shennan, A. H., Groen, H. & Chappell, L. C., 26 Apr 2022, (E-pub ahead of print) In: American Journal of Obstetrics and Gynecology. YMOB 14448.

    Research output: Contribution to journalReview articlepeer-review

  3. Postnatal health and care following hypertensive disorders in pregnancy: a prospective cohort study (BPiPP study)

    BPiPP study group, 5 Apr 2022, In: BMC Pregnancy and Childbirth. 22, 1, p. 286 12 p.

    Research output: Contribution to journalArticlepeer-review

  4. Sulfated Progesterone Metabolites That Enhance Insulin Secretion Via Trpm3 are Reduced in Serum From Women with Gestational Diabetes Mellitus

    Fan, H. M., Mitchell, A. L., Bellafante, E., McIlvride, S., Primicheru, L. I., Giorgi, M., Eberini, I., Syngelaki, A., Lövgren-Sandblom, A., Jones, P., McCance, D., Sukumar, N., Periyathambi, N., Weldeselassie, Y., Hunt, K. F., Nicolaides, K. H., Andersson, D., Bevan, S., Seed, P. T., Bewick, G. A. & 5 others, Bowe, J. E., Fraternali, F., Saravanan, P., Marschall, H. & Williamson, C., 1 Apr 2022, In: Diabetes. 71, 4, p. 837-852 16 p.

    Research output: Contribution to journalArticlepeer-review

  5. Prevention of gestational diabetes in pregnant women with obesity: protocol for a pilot randomised controlled trial

    Quotah, O. F., Nishku, G., Hunt, J., Seed, P. T., Gill, C., Brockbank, A., Fafowora, O., Vasiloudi, I., Olusoga, O., Cheek, E., Phillips, J., Nowak, K. G., Poston, L., White, S. & Flynn, A. C., 25 Mar 2022, In: Pilot and Feasibility Studies. 8, 1, p. 70 9 p., 70.

    Research output: Contribution to journalArticlepeer-review

  6. Rule-in and rule-out of pre-eclampsia using DELFIA Xpress PlGF 1-2-3 and sFlt-1: PlGF ratio

    Bremner, L., Gill, C., Seed, P. T., Conti-Ramsden, F., Webster, L., Fleminger, J., Chappell, L. C., Shennan, A. & Bramham, K., Mar 2022, In: Pregnancy Hypertension. 27, p. 96-102 7 p.

    Research output: Contribution to journalArticlepeer-review

  7. 2021
  8. Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial

    Fleminger, J., Duhig, K., Seed, P. T., Brocklehurst, P., Green, M., Juszczak, E., Marlow, N., Shennan, A. & Chappell, L., 1 Dec 2021, In: Pregnancy Hypertension. 26, p. 91-93 3 p.

    Research output: Contribution to journalArticlepeer-review

  9. Impact of maternal obesity on neonatal heart rate and cardiac size

    Groves, A. M., Price, A. N., Russell-Webster, T., Jhaveri, S., Yang, Y., Battersby, E. E., Shahid, S., Costa Vieira, M., Hughes, E., Miller, F., Briley, A. L., Singh, C., Seed, P. T., Chowienczyk, P. J., Stern, K. W. D., Cohen, J., Pasupathy, D., Edwards, A. D., Poston, L. & Taylor, P. D., 17 Nov 2021, (E-pub ahead of print) In: ADC Fetal & Neonatal. 7 p.

    Research output: Contribution to journalArticlepeer-review

  10. The impact of chronic kidney disease Stages 3-5 on pregnancy outcomes

    Wiles, K., Webster, P., Seed, P. T., Bennett-Richards, K., Bramham, K., Brunskill, N., Carr, S., Hall, M., Khan, R., Nelson-Piercy, C., Webster, L. M., Chappell, L. C. & Lightstone, L., 9 Nov 2021, In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 36, 11, p. 2008-2017 10 p.

    Research output: Contribution to journalArticlepeer-review

  11. Can birth outcome inequality be reduced using targeted caseload midwifery in a deprived diverse inner city population? A retrospective cohort study, London, UK

    Hadebe, R., Seed, P. T., Essien, D., Headen, K., Mahmud, S., Owasil, S., Fernandez Turienzo, C., Stanke, C., Sandall, J., Bruno, M., Khazaezadeh, N. & Oteng-Ntim, E., 1 Nov 2021, In: BMJ Open. 11, 11, e049991.

    Research output: Contribution to journalArticlepeer-review

  12. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: A systematic review and individual participant data meta-analysis

    ICP_IPD_meta_analysis, 1 Sep 2021, In: Obstetrical and Gynecological Survey. 76, 9, p. 521-523 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  13. Re-evaluating diagnostic thresholds for intrahepatic cholestasis of pregnancy: case-control and cohort study

    Mitchell, A. L., Ovadia, C., Syngelaki, A., Souretis, K., Martineau, M., Girling, J., Vasavan, T., Fan, H. M., Seed, P. T., Chambers, J., Walters, J. R. F., Nicolaides, K. & Williamson, C., Sep 2021, In: BJOG. 128, 10, p. 1635-1644 10 p.

    Research output: Contribution to journalArticlepeer-review

  14. Multicenter Cohort Study, With a Nested Randomized Comparison, to Examine the Cardiovascular Impact of Preterm Preeclampsia

    McCarthy, F. P., O'Driscoll, J. M., Seed, P. T., Placzek, A., Gill, C., Sparkes, J., Poston, L., Marber, M., Shennan, A. H., Thilaganathan, B., Leeson, P. & Chappell, L. C., 30 Aug 2021, (E-pub ahead of print) In: Hypertension (Dallas, Tex. : 1979). 78, 3, p. 1382-1394 13 p.

    Research output: Contribution to journalArticlepeer-review

  15. Cervicovaginal microbiota and metabolome predict preterm birth risk in an ethnically diverse cohort

    Flaviani, F., Hezelgrave, N. L., Kanno, T., Prosdocimi, E. M., Chin-Smith, E., Ridout, A. E., von Maydell, D. K., Mistry, V., Wade, W. G., Shennan, A. H., Dimitrakopoulou, K., Seed, P. T., Mason, A. J. & Tribe, R. M., 23 Aug 2021, In: JCI Insight. 6, 16, 16 p., e149257.

    Research output: Contribution to journalArticlepeer-review

  16. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

    Ovadia, C., Sajous, J., Seed, P. T., Patel, K., Williamson, N. J., Attilakos, G., Azzaroli, F., Bacq, Y., Batsry, L., Broom, K., Brun-Furrer, R., Bull, L., Chambers, J., Cui, Y., Ding, M., Dixon, P. H., Estiú, M. C., Gardiner, F. W., Geenes, V., Grymowicz, M. & 30 others, Günaydin, B., Hague, W. M., Haslinger, C., Hu, Y., Indraccolo, U., Juusela, A., Kane, S. C., Kebapcilar, A., Kebapcilar, L., Kohari, K., Kondrackienė, J., Koster, M. P. H., Lee, R. H., Liu, X., Locatelli, A., Macias, R. I. R., Madazli, R., Majewska, A., Maksym, K., Marathe, J. A., Morton, A., Oudijk, M. A., Öztekin, D., Peek, M. J., Shennan, A. H., Tribe, R. M., Tripodi, V., Vasavan, T., Chappell, L. C. & Williamson, C., Jul 2021, In: The Lancet Gastroenterology & Hepatology. 6, 7, p. 547-558 12 p.

    Research output: Contribution to journalArticlepeer-review

  17. Validation of the BPro radial pulse waveform acquisition device in pregnancy and gestational hypertensive disorders

    Jakes, A., Wade, J., Vowles, Z., Seed, P. T., Shennan, A. H., Chappell, L. C. & Nzelu, D., 14 Jun 2021, (E-pub ahead of print) In: BLOOD PRESSURE MONITORING. p. 380-384 5 p.

    Research output: Contribution to journalArticlepeer-review

  18. Placental and endothelial biomarkers for the prediction of superimposed pre-eclampsia in chronic kidney disease

    Wiles, K., Bramham, K., Seed, P. T., Brockbank, A., Nelson-Piercy, C., Karumanchi, S. A., Lightstone, L. & Chappell, L. C., Jun 2021, In: Pregnancy Hypertension. 24, p. 58-64 7 p.

    Research output: Contribution to journalArticlepeer-review

  19. Prognostic indicators of severe disease in late preterm pre-eclampsia to guide decision making on timing of delivery: The PEACOCK study

    Duhig, K. E., Seed, P. T., Placzek, A., Sparkes, J., Hendy, E., Gill, C., Brockbank, A., Shennan, A. H., Thangaratinam, S. & Chappell, L. C., Jun 2021, In: Pregnancy Hypertension. 24, p. 90-95 6 p.

    Research output: Contribution to journalArticlepeer-review

  20. A prognostic model to guide decision-making on timing of delivery in late preterm pre-eclampsia: the PEACOCK prospective cohort study

    Duhig, K., Seed, P. T., Placzek, A., Sparkes, J., Gill, C., Brockbank, A., Shennan, A., Thangaratinam, S. & Chappell, L. C., 1 May 2021, In: Health technology assessment (Winchester, England). 25, 30, p. 1-32 32 p.

    Research output: Contribution to journalArticlepeer-review

  21. Brain volumetry in fetuses that deliver very preterm: An MRI pilot study

    Story, L., Davidson, A., Patkee, P., Fleiss, B., Kyriakopoulou, V., Colford, K., Sankaran, S., Seed, P., Jones, A., Hutter, J., Shennan, A. & Rutherford, M., 29 Mar 2021, (E-pub ahead of print) In: NeuroImage: Clinical. 30, p. 102650 102650.

    Research output: Contribution to journalArticlepeer-review

  22. Adiposity and cardiovascular outcomes in three-year-old children of participants in UPBEAT, an RCT of a complex intervention in pregnant women with obesity

    on behalf of the UPBEAT consortium, Mar 2021, In: Pediatric Obesity. 16, 3, e12725.

    Research output: Contribution to journalArticlepeer-review

  23. Placental growth factor measurements in the assessment of women with suspected Preeclampsia: A stratified analysis of the PARROT trial

    Duhig, K. E., Myers, J. E., Gale, C., Girling, J. C., Harding, K., Sharp, A., Simpson, N. A. B., Tuffnell, D., Seed, P. T., Shennan, A. H. & Chappell, L. C., Mar 2021, In: Pregnancy Hypertension. 23, p. 41-47 7 p.

    Research output: Contribution to journalArticlepeer-review

  24. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: an individual participant data meta-analysis

    Ovadia, C., Sajous, J., Seed, P. T., Patel, K., Williamson, N. J., Attilakos, G., Azzaroli, F., Bacq, Y., Batsry, L., Broom, K., Brun-Furrer, R., Bull, L., Chambers, J., Cui, Y., Ding, M., Dixon, P., Estiu, M., Gardiner, F., Geenes, V., Grymowicz, M. & 37 others, Gunaydin, B., Hague, W., Haslinger, C., Hu, Y., Indraccolo, U., Juusela, A., Kane, S., Kebapcilar, A., Kebapcilar, L., Kohari, K., Kondrackiene, J., Koster, M., Lee, R., Liu, X., Locatelli, A., Macias, R., Madazli, R., Majewska, A., Maksym, K., Marathe, J., Morton, A., Oudijk, M., Oztekin, D., Peek, M., Shennan, A., Tribe, R., Tripodi, V., Turk Ozterlemez, N., Vasavan, T., Wong, L. F. A., Yinon, Y., Zhang, Q., Zloto, K., Marschall, H-U., Thornton, J., Chappell, L. & Williamson, C., 22 Feb 2021, (Accepted/In press) In: The Lancet Gastroenterology & Hepatology. p. 1-25 25 p.

    Research output: Contribution to journalArticlepeer-review

  25. Re-evaluating diagnostic thresholds for intrahepatic cholestasis of pregnancy: case-control and cohort study

    Mitchell, A., Ovadia, C., Syngelaki, A., Souretis, K., Martineau, M. G., Girling, J., Vasavan, T., Fan, C., Seed, P. T., Chambers, J., Walters, J. R. F., Nicolaides, K. H. & Williamson, C., 12 Feb 2021, (Accepted/In press) In: British Journal of Obstetrics and Gynaecology.

    Research output: Contribution to journalArticlepeer-review

  26. The effect of smoking on COVID-19 severity: a systematic review and meta-analysis

    Reddy, R. K., Charles, W. N., Sklavounos, A., Dutt, A., Seed, P. T. & Khajuria, A., Feb 2021, In: Journal of Medical Virology. 93, 2, p. 1045-1056 12 p.

    Research output: Contribution to journalArticlepeer-review

  27. Placental magnetic resonance imaging in chronic hypertension: A case-control study

    Ho, A., Hutter, J., Slator, P., Jackson, L., Seed, P. T., Mccabe, L., Al-Adnani, M., Marnerides, A., George, S., Story, L., Hajnal, J. V., Rutherford, M. & Chappell, L. C., 15 Jan 2021, In: Placenta. 104, p. 138-145 8 p.

    Research output: Contribution to journalArticlepeer-review

  28. DNA methylation signatures in cord blood associated with birthweight are enriched for dmCpGs previously associated with maternal hypertension or pre-eclampsia, smoking and folic acid intake

    UPBEAT Consortium/EpiGen Consortium, 2021, (Accepted/In press) In: Epigenetics.

    Research output: Contribution to journalArticlepeer-review

  29. The DNA methylation signatures in cord blood of neonates associated with birthweight are enriched for dmCpGs associated with maternal hypertension and folate intake

    Antoun, E., Titcombe, P., Dalrymple, K., Flynn, A. C., Poston, L., White, S., Seed, P. T., Inskip, H. M., Hanson, M. A., Cooper, C., Kitaba, N. T., Barton, S. J., Garratt, E. S., Murray, R., Godfrey, K. M. & Lillycrop, K. A., 2021, (Accepted/In press) In: Epigenetics.

    Research output: Contribution to journalArticlepeer-review

  30. 2020
  31. Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations

    Vasavan, T., Deepak, S., Jayawardane, I. A., Lucchini, M., Martin, C., Geenes, V., Yang, J., Lövgren-Sandblom, A., Seed, P. T., Chambers, J., Stone, S., Kurlak, L., Dixon, P. H., Marschall, H-U., Gorelik, J., Chappell, L., Loughna, P., Thornton, J., Pipkin, F. B., Hayes-Gill, B. & 2 others, Fifer, W. P. & Williamson, C., 1 Dec 2020, (E-pub ahead of print) In: Journal of Hepatology. 0, 0, p. 1-10

    Research output: Contribution to journalArticlepeer-review

  32. Placental growth factor for the prognosis of women with preeclampsia (fullPIERS model extension): context matters

    fullPIERS Group, 1 Dec 2020, In: BMC Pregnancy and Childbirth. 20, 1, p. 668 1 p., 668.

    Research output: Contribution to journalArticlepeer-review

  33. Maternal dysglycaemia, changes in the infant’s epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial

    UPBEAT Consortium, Antoun, E., Kitaba, N. T., Titcombe, P., Dalrymple, K. V., Garratt, E. S., Barton, S. J., Murray, R., Seed, P. T., Holbrook, J. D., Kobor, M. S., Lin, D. T. S., MacIsaac, J. L., Burdge, G. C., White, S. L., Poston, L., Godfrey, K. M. & Lillycrop, K. A., 5 Nov 2020, In: PLoS Medicine. 17, 11, 29 p., e1003229.

    Research output: Contribution to journalArticlepeer-review

  34. External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis

    IPPIC Collaborative Network, 2 Nov 2020, In: BMC Medicine. 18, 1, p. 302 1 p.

    Research output: Contribution to journalArticlepeer-review

  35. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a secondary analysis of the PITCHES trial

    Fleminger, J., Seed, P. T., Smith, A., Juszczak, E., Dixon, P. H., Chambers, J., Dorling, J., Williamson, C., Thornton, J. G. & Chappell, L., 16 Oct 2020, (E-pub ahead of print) In: BJOG.

    Research output: Contribution to journalArticlepeer-review

  36. Midwifery continuity of care versus standard maternity care for women at increased risk of preterm birth: A hybrid implementation–effectiveness, randomised controlled pilot trial in the UK

    Fernandez Turienzo, C., Bick, D., Briley, A., Bollard, M., Coxon, K., Cross, P., Silverio, S. A., Singh, C., Seed, P., Tribe, R., Shennan, A., Sandall, J. & on behalf of the POPPIE Pilot Collaborative Group, 6 Oct 2020, In: PLoS Medicine. 17, 10, e1003350.

    Research output: Contribution to journalArticlepeer-review

  37. Quantitative fetal fibronectin for prediction of preterm birth in asymptomatic twin pregnancy

    Kuhrt, K., Hezelgrave-Elliott, N., Stock, S. J., Tribe, R., Seed, P. T. & Shennan, A. H., 1 Sep 2020, In: Acta Obstetricia et Gynecologica Scandinavica. 99, 9, p. 1191-1197 7 p.

    Research output: Contribution to journalArticlepeer-review

  38. Antenatal thymus volumes in fetuses that delivered <32 weeks gestation: an MRI pilot study

    Story, L., Zhang, T., Uus, A., Hutter, J., Egloff, A., Gibbons, D., Alison, H., Al-Adnani, M., Knight, C. L., Theodoulou, I., Deprez, M., Seed, P. T., Tribe, R. M., Shennan, A. H. & Rutherford, M., 31 Aug 2020, (E-pub ahead of print) In: Acta Obstetricia et Gynecologica Scandinavica. 0, 0, p. 1-11

    Research output: Contribution to journalArticlepeer-review

  39. Impact of smoking on coronavirus disease 19 severity

    Reddy, R. K., Charles, W. N., Sklavounos, A., Seed, P. T. & Khajuria, A., 25 Aug 2020, (E-pub ahead of print) In: Journal of Medical Virology. p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

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