King's College London

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Research Outputs

  1. 2017
  2. IgG glycosylation and DNA methylation are interconnected with smoking

    Wahl, A. , Kasela, S. , Monotoro, E. C. , van Iterson, M. , Štambuk, J. , Sharma, S. , van den Akker, E. , Klaric, L. , Benedetti, E. , Razdorov, G. , Trbojević-Akmačić, I. , Vučković, F. , Ugrina, I. , Beekman, M. , Deelen, J. , van Heemst, D. , Heijmans, B. T. , Consortium, B. I. O. S. , Wuhrer, M. , Plomp, R. & 14 others Keser, T., Šimurina, M., Pavić, T., Gudelj, I., Krištić, J., Grallert, H., Kunze, S., Peters, A., Bell, J. T., Spector, T. D., Milani, L., Eline Slagboom, P., Lauc, G. & Gieger, C. 18 Oct 2017 In : BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS.

    Research output: Contribution to journalArticle

  3. Association of the resolvin precursor 17-HDHA, but not D-or E-series resolvins, with heat pain sensitivity and osteoarthritis pain in humans

    Valdes, A. M., Ravipati, S., Menni, C., Abhishek, A., Metrustry, S., Harris, J., Nessa, A., Williams, F. M. K., Spector, T. D., Doherty, M., Chapman, V. & Barrett, D. A. 1 Dec 2017 In : Scientific Reports. 7, 1, 10748

    Research output: Contribution to journalArticle

  4. Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood

    Lukowski, S. W., Lloyd-Jones, L. R., Holloway, A., Kirsten, H., Hemani, G., Yang, J., Small, K., Zhao, J., Metspalu, A., Dermitzakis, E. T., Gibson, G., Spector, T. D., Thiery, J., Scholz, M., Montgomery, G. W., Esko, T., Visscher, P. M. & Powell, J. E. 1 Dec 2017 In : Nature Communications. 8, 1, 483

    Research output: Contribution to journalArticle

  5. Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

    Shen, X., Klarić, L., Sharapov, S., Mangino, M., Ning, Z., Wu, D., Trbojević-Akmačić, I., Pučić-Baković, M., Rudan, I., Polašek, O., Hayward, C., Spector, T. D., Wilson, J. F., Lauc, G. & Aulchenko, Y. S. 6 Sep 2017 In : Nature Communications. 8, 1, 447

    Research output: Contribution to journalArticle

  6. Genome-Wide Association Reveals Pigmentation Genes Play a Role in Skin Aging

    Law, M. H. , Medland, S. E. , Zhu, G. , Yazar, S. , Viñuela, A. , Wallace, L. , Shekar, S. N. , Duffy, D. L. , Bataille, V. , Glass, D. , Spector, T. D. , Wood, D. , Gordon, S. D. , Barbour, J. M. , Henders, A. K. , Hewitt, A. W. , Montgomery, G. W. , Sturm, R. A. , Mackey, D. A. , Green, A. C. & 2 others Martin, N. G. & MacGregor, S. Sep 2017 In : Journal of Investigative Dermatology. 137, 9, p. 1887-1894

    Research output: Contribution to journalArticle

  7. Genetic and environmental influences on stability and change in baseline levels of C-reactive protein: A longitudinal twin study

    Sas, A. A., Vaez, A., Jamshidi, Y., Nolte, I. M., Kamali, Z., Spector, T. D., Riese, H. & Snieder, H. 31 Aug 2017 In : Atherosclerosis.

    Research output: Contribution to journalArticle

  8. Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand

    Hollander, W. D. , Boer, C. G. , Hart, D. J. , Yau, M. S. , Ramos, Y. F. M. , Metrustry, S. , Broer, L. , Deelen, J. , Cupples, L. A. , Rivadeneira, F. , Kloppenburg, M. , Peters, M. , Spector, T. D. , Hofman, A. , Slagboom, P. E. , Nelissen, R. G. H. H. , Uitterlinden, A. G. , Felson, D. T. , Valdes, A. M. , Meulenbelt, I. & 1 others van Meurs, J. J. B. 30 Aug 2017 In : Annals of the rheumatic diseases.

    Research output: Contribution to journalArticle

  9. Epigenetic discrimination of identical twins from blood under the forensic scenario

    Vidaki, A., López, C. D., Carnero-Montoro, E., Ralf, A., Ward, K., Spector, T., Bell, J. T. & Kayser, M. Nov 2017 In : Forensic Science International-Genetics. 31, p. 67-80 14 p.

    Research output: Contribution to journalArticle

  10. Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: An individual-based pooled analysis of 40 twin cohorts

    Silventoinen, K. , Jelenkovic, A. , Sund, R. , Yokoyama, Y. , Hur, Y. M. , Cozen, W. , Hwang, A. E. , Mack, T. M. , Honda, C. , Inui, F. , Iwatani, Y. , Watanabe, M. , Tomizawa, R. , Pietilainen, K. H. , Rissanen, A. , Siribaddana, S. H. , Hotopf, M. , Sumathipala, A. , Rijsdijk, F. , Tan, Q. & 82 others Zhang, D., Pang, Z., Piirtola, M., Aaltonen, S., Oncel, S. Y., Aliev, F., Rebato, E., Hjelmborg, J. B., Christensen, K., Skytthe, A., Kyvik, K. O., Silberg, J. L., Eaves, L. J., Cutler, T. L., Ordonana, J. R., Sanchez-Romera, J. F., Colodro-Conde, L., Song, Y. M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H. U., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Spector, T. D., Mangino, M., Lachance, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Huibregtse, B. M., Bartels, M., Van Beijsterveldt, C. E. M., Willemsen, G., Goldberg, J. H., Rasmussen, F., Tarnoki, A. D., Tarnoki, D. L., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Hopper, J. L., Sung, J., Maes, H. H., Turkheimer, E., Boomsma, D. I., Sørensen, T. I. A. & Kaprio, J. 1 Aug 2017 In : American Journal of Clinical Nutrition. 106, 2, p. 457-466 10 p.

    Research output: Contribution to journalArticle

  11. Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS

    Rosenberger, G., Liu, Y., Röst, H. L., Ludwig, C., Buil, A., Bensimon, A., Soste, M., Spector, T. D., Dermitzakis, E. T., Collins, B. C., Malmström, L. & Aebersold, R. 1 Aug 2017 In : Nature Biotechnology. 35, 8, p. 781-788 8 p.

    Research output: Contribution to journalArticle

  12. Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene

    Warner, S. C., Walsh, D. A., Laslett, L. L., Maciewicz, R. A., Soni, A., Hart, D. J., Zhang, W., Muir, K. R., Dennison, E. M., Leaverton, P., Rampersaud, E., Cooper, C., Spector, T. D., Cicuttini, F. M., Arden, N. K., Jones, G., Doherty, M. & Valdes, A. M. Aug 2017 In : European journal of pain (London, England). p. 1277-1284

    Research output: Contribution to journalArticle

  13. Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain

    Menni, C., Migaud, M., Kastenmüller, G., Pallister, T., Zierer, J., Peters, A., Mohney, R. P., Spector, T. D., Bagnardi, V., Gieger, C., Moore, S. C. & Valdes, A. M. 31 Jul 2017 In : Obesity. 25, 9, p. 1618-1624

    Research output: Contribution to journalArticle

  14. Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker

    Cole, J. H., Poudel, R. P. K., Tsagkrasoulis, D., Caan, M. W. A., Steves, C., Spector, T. D. & Montana, G. 29 Jul 2017 In : NeuroImage. p. 115-124

    Research output: Contribution to journalArticle

  15. Affective responses to sweet products and sweet solution in British and Finnish adults

    Tuorila, H., Keskitalo-Vuokko, K., Perola, M., Spector, T. & Kaprio, J. 1 Jul 2017 In : FOOD QUALITY AND PREFERENCE.

    Research output: Contribution to journalArticle

  16. Serum Lipid Levels and Risk of Hand Osteoarthritis: The Chingford Prospective Cohort Study

    Garcia-Gil, M., Reyes, C., Ramos, R., Sanchez-Santos, M. T., Prieto-Alhambra, D., Spector, T. D., Hart, D. J. & Arden, N. K. 9 Jun 2017 In : Scientific Reports. 7, 1, 3147

    Research output: Contribution to journalArticle

  17. Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

    Tachmazidou, I. , Süveges, D. , Min, J. L. , Ritchie, G. R. S. , Steinberg, J. , Walter, K. , Iotchkova, V. , Schwartzentruber, J. , Huang, J. , Memari, Y. , McCarthy, S. , Crawford, A. A. , Bombieri, C. , Cocca, M. , Farmaki, A-E. , Gaunt, T. R. , Jousilahti, P. , Kooijman, M. N. , Lehne, B. , Malerba, G. & 83 others Männistö, S., Matchan, A., Medina-Gomez, C., Metrustry, S. J., Nag, A., Ntalla, I., Paternoster, L., Rayner, N. W., Sala, C., Scott, W. R., Shihab, H. A., Southam, L., St Pourcain, B., Traglia, M., Trajanoska, K., Zaza, G., Zhang, W., Artigas, M. S., Bansal, N., Benn, M., Chen, Z., Danecek, P., Lin, W-Y., Locke, A., Luan, J., Manning, A. K., Mulas, A., Sidore, C., Tybjaerg-Hansen, A., Varbo, A., Zoledziewska, M., Finan, C., Hatzikotoulas, K., Hendricks, A. E., Kemp, J. P., Moayyeri, A., Panoutsopoulou, K., Szpak, M., Wilson, S. G., Boehnke, M., Cucca, F., Di Angelantonio, E., Langenberg, C., Lindgren, C., McCarthy, M. I., Morris, A. P., Nordestgaard, B. G., Scott, R. A., Tobin, M. D., Wareham, N. J., Burton, P., Chambers, J. C., Smith, G. D., Dedoussis, G., Felix, J. F., Franco, O. H., Gambaro, G., Gasparini, P., Hammond, C. J., Hofman, A., Jaddoe, V. W. V., Kleber, M., Kooner, J. S., Perola, M., Relton, C., Ring, S. M., Rivadeneira, F., Salomaa, V., Spector, T. D., Stegle, O., Toniolo, D., Uitterlinden, A. G., Barroso, I., Greenwood, C. M. T., Perry, J. R. B., Walker, B. R., Butterworth, A. S., Xue, Y., Durbin, R., Small, K. S., Soranzo, N., Timpson, N. J. & Zeggini, E. 1 Jun 2017 In : American Journal of Human Genetics. 100, 6, p. 865–884

    Research output: Contribution to journalArticle

  18. Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain

    Livshits, G., Malkin, I., Freydin, M. B., Xia, Y., Gao, F., Wang, J., Spector, T. D., MacGregor, A., Bell, J. T. & Williams, F. M. K. Jun 2017 In : Pain. 158, 6, p. 1053-1062 10 p.

    Research output: Contribution to journalArticle

  19. Effects of statins on the immunoglobulin G glycome

    Keser, T., Vučković, F., Barrios, C., Zierer, J., Wahl, A., Akinkuolie, A. O., Štambuk, J., Nakić, N., Pavić, T., Periša, J., Mora, S., Gieger, C., Menni, C., Spector, T. D., Gornik, O. & Lauc, G. 1 May 2017 In : BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 1861, 5, p. 1152-1158 7 p.

    Research output: Contribution to journalArticle

  20. Could food act as personalized medicine for chronic disease?

    Toribio-Mateas, M. A. & Spector, T. D. May 2017 In : Future Medicine. 14, 3, p. 193-196 4 p.

    Research output: Contribution to journalComment/debate

  21. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E. , Winkler, T. W. , Feitosa, M. F. , Graff, M. , Fisher, V. A. , Young, K. , Barata, L. , Deng, X. , Czajkowski, J. , Hadley, D. , Ngwa, J. S. , Ahluwalia, T. S. , Chu, A. Y. , Heard-costa, N. L. , Lim, E. , Perez, J. , Eicher, J. D. , Kutalik, Z. , Xue, L. , Mahajan, A. & 297 others Renström, F., Wu, J., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg, J., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., Van Der Laan, S. W., Van Der Most, P. J., Van Vliet-ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., De Borst, G. J., De Craen, A. J. M., De Geus, E. J. C., Dedoussis, G., Delgado, G. E., Den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-kähönen, N., Ingelsson, E., James, A. L., Jansson, J., Jarvelin, M., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-vidal, P., Martin, N. G., Mckenzie, C. A., Mcknight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. ., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-torvik, L. J., Rawal, R., Rice, T., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., Faire, U. D., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-larsen, P., Grabe, H. J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., Mccarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., Van Der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., Van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J., Loos, R. J. F., Kilpeläinen, T. O., Liu, C., Borecki, I. B., North, K. E. & Cupples, L. A. 26 Apr 2017 In : Nature Communications. 8, 14977

    Research output: Contribution to journalArticle

  22. Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Day, F. R. , Thompson, D. J. , Helgason, H. , Chasman, D. I. , Finucane, H. , Sulem, P. , Ruth, K. S. , Whalen, S. , Sarkar, A. K. , Albrecht, E. , Altmaier, E. , Amini, M. , Barbieri, C. M. , Boutin, T. , Campbell, A. , Demerath, E. , Giri, A. , He, C. , Hottenga, J. J. , Karlsson, R. & 196 others Kolcic, I., Loh, P. R., Lunetta, K. L., Mangino, M., Marco, B., McMahon, G., Medland, S. E., Nolte, I. M., Noordam, R., Nutile, T., Paternoster, L., Perjakova, N., Porcu, E., Rose, L. M., Schraut, K. E., Segrè, A. V., Smith, A. V., Stolk, L., Teumer, A., Andrulis, I. L., Bandinelli, S., Beckmann, M. W., Benitez, J., Bergmann, S., Bochud, M., Boerwinkle, E., Bojesen, S. E., Bolla, M. K., Brand, J. S., Brauch, H., Brenner, H., Broer, L., Brüning, T., Buring, J. E., Campbell, H., Catamo, E., Chanock, S., Chenevix-Trench, G., Corre, T., Couch, F. J., Cousminer, D. L., Cox, A., Crisponi, L., Czene, K., Davey Smith, G., de Geus, E. J. C. N., de Mutsert, R., de Vivo, I., Dennis, J., Devilee, P., dos-Santos-Silva, I., Dunning, A. M., Eriksson, J. G., Fasching, P. A., Fernández-Rhodes, L., Ferrucci, L., Flesch-Janys, D., Franke, L., Gabrielson, M., Gandin, I., Giles, G. G., Grallert, H., Gudbjartsson, D. F., Guénel, P., Hall, P., Hallberg, E., Hamann, U., Harris, T. B., Hartman, C. A., Heiss, G., Hooning, M. J., Hopper, J. L., Hu, F., Hunter, D. J., Ikram, M. A., Im, H. K., Järvelin, M. R., Joshi, P. K., Karasik, D., Kellis, M., Kutalik, Z., LaChance, G., Lambrechts, D., Langenberg, C., Launer, L. J., Laven, J. S. E., Lenarduzzi, S., Li, J., Lind, P. A., Lindstrom, S., Liu, Y. M., Luan, J., Mägi, R., Mannermaa, A., Mbarek, H., McCarthy, M. I., Meisinger, C., Meitinger, T., Menni, C., Metspalu, A., Michailidou, K., Milani, L., Milne, R. L., Montgomery, G. W., Mulligan, A. M., Nalls, M. A., Navarro, P., Nevanlinna, H., Nyholt, D. R., Oldehinkel, A. J., O'Mara, T. A., Padmanabhan, S., Palotie, A., Pedersen, N., Peters, A., Peto, J., Pharoah, P. D. P., Pouta, A., Radice, P., Rahman, I., Ring, S. M., Robino, A., Rosendaal, F. R., Rudan, I., Rueedi, R., Ruggiero, D., Sala, C. F., Schmidt, M. K., Scott, R. A., Shah, M., Sorice, R., Southey, M. C., Sovio, U., Stampfer, M., Steri, M., Strauch, K., Tanaka, T., Tikkanen, E., Timpson, N. J., Traglia, M., Truong, T., Tyrer, J. P., Uitterlinden, A. G., Edwards, D. R. V., Vitart, V., Völker, U., Vollenweider, P., Wang, Q., Widen, E., van Dijk, K. W., Willemsen, G., Winqvist, R., Wolffenbuttel, B. H. R., Zhao, J. H., Zoledziewska, M., Zygmunt, M., Alizadeh, B. Z., Boomsma, D. I., Ciullo, M., Cucca, F., Esko, T., Franceschini, N., Gieger, C., Gudnason, V., Hayward, C., Kraft, P., Lawlor, D. A., Magnusson, P. K. E., Martin, N. G., Mook-Kanamori, D. O., Nohr, E. A., Polasek, O., Porteous, D., Price, A. L., Ridker, P. M., Snieder, H., Spector, T. D., Stöckl, D., Toniolo, D., Ulivi, S., Visser, J. A., Völzke, H., Wareham, N. J., Wilson, J. F., Spurdle, A. B., Thorsteindottir, U., Pollard, K. S., Easton, D. F., Tung, J. Y., Chang-Claude, J., Hinds, D., Murray, A., Murabito, J. M., Stefansson, K., Ong, K. K. & Perry, J. R. B. 24 Apr 2017 In : Nature Genetics. p. 834-841

    Research output: Contribution to journalArticle

  23. Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping

    Tsagkrasoulis, D., Hysi, P., Spector, T. & Montana, G. 19 Apr 2017 In : Scientific Reports. 7, 45885

    Research output: Contribution to journalArticle

  24. Molecular pathways associated with blood pressure and hexadecanedioate levels

    Menni, C., Metrustry, S. J., Ehret, G., Dominiczak, A. F., Chowienczyk, P., Spector, T. D., Padmanabhan, S. & Valdes, A. M. 12 Apr 2017 In : PloS one. 12, 4, p. e0175479

    Research output: Contribution to journalArticle

  25. Epigenome-wide association of DNA methylation in whole blood with bone mineral density

    Morris, J. A., Tsai, P-C., Joehanes, R., Zheng, J., Trajanoska, K., Soerensen, M., Forgetta, V., Castillo-Fernandez, J. E., Frost, M., Spector, T. D., Christensen, K., Christiansen, L., Rivadeneira, F., Tobias, J. H., Evans, D. M., Kiel, D. P., Hsu, Y-H., Richards, J. B. & Bell, J. T. 10 Apr 2017 In : Journal of Bone and Mineral Research.

    Research output: Contribution to journalArticle

  26. Telomeres and the natural lifespan limit in humans

    Steenstrup, T. , Kark, J. D. , Verhulst, S. , Thinggaard, M. , Hjelmborg, J. V. B. , Dalgård, C. , Kyvik, K. O. , Christiansen, L. , Mangino, M. , Spector, T. D. , Petersen, I. , Kimura, M. , Benetos, A. , Labat, C. , Sinnreich, R. , Hwang, S. J. , Levy, D. , Hunt, S. C. , Fitzpatrick, A. L. , Chen, W. & 9 others Berenson, G. S., Barbieri, M., Paolisso, G., Gadalla, S. M., Savage, S. A., Christensen, K., Yashin, A. I., Arbeev, K. G. & Aviv, A. 6 Apr 2017 In : Aging. 9, 4, p. 1130-1142 13 p.

    Research output: Contribution to journalArticle

  27. Time-dependent genetic effects on gene expression implicate aging processes

    Bryois, J., Buil, A., Ferreira, P. G., Panousis, N. I., Brown, A. A., Viñuela, A., Planchon, A., Bielser, D., Small, K., Spector, T. & Dermitzakis, E. T. 1 Apr 2017 In : Genome Research. 27, 4, p. 545-552 8 p.

    Research output: Contribution to journalArticle

  28. Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

    Long, T. , Hicks, M. , Yu, H. C. , Biggs, W. H. , Kirkness, E. F. , Menni, C. , Zierer, J. , Small, K. S. , Mangino, M. , Messier, H. , Brewerton, S. , Turpaz, Y. , Perkins, B. A. , Evans, A. M. , Miller, L. A. D. , Guo, L. , Caskey, C. T. , Schork, N. J. , Garner, C. , Spector, T. D. & 2 others Venter, J. C. & Telenti, A. 30 Mar 2017 In : Nature Genetics. 49, 4, p. 568-578 11 p.

    Research output: Contribution to journalArticle

  29. DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

    Castillo-Fernandez, J. E., Loke, Y. J., Bass-Stringer, S., Gao, F., Xia, Y., Wu, H., Lu, H., Liu, Y., Wang, J., Spector, T. D., Saffery, R., Craig, J. M. & Bell, J. T. 24 Mar 2017 In : Genome medicine. 9, 1, 28

    Research output: Contribution to journalArticle

  30. Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness

    Heilmann-Heimbach, S. , Herold, C. , Hochfeld, L. M. , Hillmer, A. M. , Nyholt, D. R. , Hecker, J. , Javed, A. , Chew, E. G. Y. , Pechlivanis, S. , Drichel, D. , Heng, X. T. , Del Rosario, R. C. H. , Fier, H. L. , Paus, R. , Rueedi, R. , Galesloot, T. E. , Moebus, S. , Anhalt, T. , Prabhakar, S. , Li, R. & 16 others Kanoni, S., Papanikolaou, G., Kutalik, Z., Deloukas, P., Philpott, M. P., Waeber, G., Spector, T. D., Vollenweider, P., Kiemeney, L. A. L. M., Dedoussis, G., Richards, J. B., Nothnagel, M., Martin, N. G., Becker, T., Hinds, D. A. & Nöthen, M. M. 8 Mar 2017 In : Nature Communications. 8, 14694

    Research output: Contribution to journalArticle

  31. Genetic variation at 16q24.2 is associated with small vessel stroke

    Traylor, M. , Malik, R. , Nalls, M. A. , Cotlarciuc, I. , Radmanesh, F. , Thorleifsson, G. , Hanscombe, K. B. , Langefeld, C. , Saleheen, D. , Rost, N. S. , Yet, I. , Spector, T. D. , Bell, J. T. , Hannon, E. , Mill, J. , Chauhan, G. , Debette, S. , Bis, J. C. , Longstreth, W. T. , Ikram, M. A. & 47 others Launer, L. J., Seshadri, S., Hamilton-Bruce, M. A., Jimenez-Conde, J., Cole, J. W., Schmidt, R., Słowik, A., Lemmens, R., Lindgren, A., Melander, O., Grewal, R. P., Sacco, R. L., Rundek, T., Rexrode, K., Arnett, D. K., Johnson, J. A., Benavente, O. R., Wasssertheil-Smoller, S., Lee, J. M., Pulit, S. L., Wong, Q., Rich, S. S., de Bakker, P. I. W., McArdle, P. F., Woo, D., Anderson, C. D., Xu, H., Heitsch, L., Fornage, M., Jern, C., Stefansson, K., Thorsteinsdottir, U., Gretarsdottir, S., Lewis, C. M., Sharma, P., Sudlow, C. L. M., Rothwell, P. M., Boncoraglio, G. B., Thijs, V., Levi, C., Meschia, J. F., Rosand, J., Kittner, S. J., Mitchell, B. D., Dichgans, M., Worrall, B. B. & Markus, H. S. 1 Mar 2017 In : Annals of Neurology. 81, 3, p. 383-394 12 p.

    Research output: Contribution to journalArticle

  32. Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Warren, H. R. , Evangelou, E. , Cabrera, C. P. , Gao, H. , Ren, M. , Mifsud, B. , Ntalla, I. , Surendran, P. , Liu, C. , Cook, J. P. , Kraja, A. T. , Drenos, F. , Loh, M. , Verweij, N. , Marten, J. , Karaman, I. , Lepe, M. P. S. , O'Reilly, P. F. , Knight, J. , Snieder, H. & 120 others Kato, N., He, J., Tai, E. S., Said, M. A., Porteous, D., Alver, M., Poulter, N., Farrall, M., Gansevoort, R. T., Padmanabhan, S., Mägi, R., Stanton, A., Connell, J., Bakker, S. J. L., Metspalu, A., Shields, D. C., Thom, S., Brown, M., Sever, P., Esko, T., Hayward, C., Van Der Harst, P., Saleheen, D., Chowdhury, R., Chambers, J. C., Chasman, D. I., Chakravarti, A., Newton-Cheh, C., Lindgren, C. M., Levy, D., Kooner, J. S., Keavney, B., Tomaszewski, M., Samani, N. J., Howson, J. M. M., Tobin, M. D., Munroe, P. B., Ehret, G. B., Wain, L. V., Barnes, M. R., Tzoulaki, I., Caulfield, M. J., Elliott, P., Völker, U., Vollenweider, P., Wild, S., Willemsen, G., Wright, A. F., Yao, J., Thériault, S., Conen, D., John, A., Sever, P., Debette, S., Mook-Kanamori, D. O., Zeggini, E., Spector, T. D., van der Harst, P., Palmer, C. N., Vergnaud, A. C., Loos, R. J., Polasek, O., Starr, J. M., Girotto, G. G., Hayward, C., Kooner, J. S., Lindgren, C. M., Vitart, V., Samani, N. J., Tuomilehto, J., Gyllensten, U., Knekt, P., Deary, I. J., Ciullo, M., Elosua, R., Keavney, B. D., Hicks, A. A., Scott, R. A., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, C. A., Salomaa, V., Toniolo, D., Perola, M., Wilson, J. F., Schmidt, H., Zhao, J. H., Lehtimäki, T., van Duijn, C. M., Gudnason, V., Psaty, B. M., Peters, A., Rettig, R., James, A., Jukema, J. W., Strachan, D. P., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, D. I., Franco, O. H., Bochud, M., Newton-Cheh, C., Munroe, P. B., Elliott, P., Chasman, D. I., Chakravarti, A., Knight, J., Morris, A. P., Levy, D., Tobin, M. D., Snieder, H., Caulfield, M. J., Ehret, G. B., Barnes, M. R., Tzoulaki, I., Caulfield, M. J. & Elliott, P. 1 Mar 2017 In : Nature Genetics. 49, 3, p. 403-415 13 p.

    Research output: Contribution to journalArticle

  33. Epigenetic Patterns in Blood Associated with Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results from Genome-Wide Association Studies

    Hedman, Å. K. , Mendelson, M. M. , Marioni, R. E. , Gustafsson, S. , Joehanes, R. , Irvin, M. R. , Zhi, D. , Sandling, J. K. , Yao, C. , Liu, C. , Liang, L. , Huan, T. , McRae, A. F. , Demissie, S. , Shah, S. , Starr, J. M. , Cupples, L. A. , Deloukas, P. , Spector, T. D. , Sundström, J. & 6 others Krauss, R. M., Arnett, D. K., Deary, I. J., Lind, L., Levy, D. & Ingelsson, E. 17 Feb 2017 In : Circulation-Cardiovascular Genetics. 10, 1, 001487

    Research output: Contribution to journalArticle

  34. Acne and Telomere Length: A New Spectrum between Senescence and Apoptosis Pathways

    Ribero, S., Sanna, M., Visconti, A., Navarini, A., Aviv, A., Glass, D., Spector, T. D., Smith, C., Simpson, M., Barker, J., Mangino, M., Falchi, M. & Bataille, V. 1 Feb 2017 In : Journal of Investigative Dermatology. 137, 2, p. 513-515 3 p.

    Research output: Contribution to journalLetter

  35. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

    Hinney, A. , Kesselmeier, M. , Jall, S. , Volckmar, A. L. , Föcker, M. , Antel, J. , Heid, I. M. , Winkler, T. W. , Grant, S. F. A. , Guo, Y. , Bergen, A. W. , Kaye, W. , Berrettini, W. , Hakonarson, H. , Herpertz-Dahlmann, B. , De Zwaan, M. , Herzog, W. , Ehrlich, S. , Zipfel, S. , Egberts, K. M. & 529 others Adan, R., Brandys, M., Van Elburg, A., Boraska Perica, V., Müller, T. D., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., Perica, V. B., Franklin, C. S., Floyd, J. A. B., Thornton, L. M., Huckins, L. M., Southam, L., Rayner, N. W., Tachmazidou, I., Klump, K. L., Treasure, J., Lewis, C. M., Schmidt, U., Tozzi, F., Iezebrink, K., Hebebrand, J., Gorwood, P., Adan, R. A. H., Kas, M. J. H., Favaro, A., Santonastaso, P., Fernández-Aranda, F., Gratacos, M., Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori-Helkamaa, A., Van Furth, E. F., Slof-Op’t Landt, M. C. T., Hudson, J. I., Reichborn-Kjennerud, T., Knudsen, G. P. S., Monteleone, P., Kaplan, A. S., Karwautz, A., Hakonarson, H., Berrettini, W. H., Guo, Y., Li, D., Schork, N. J., Komaki, G., Ando, T., Inoko, H., Esko, T., Fischer, K., Männik, K., Metspalu, A., Baker, J. H., Cone, R. D., Dackor, J., DeSocio, J. E., Hilliard, C. E., O’Toole, J. K., Pantel, J., Szatkiewicz, J. P., Taico, C., Zerwas, S., Trace, S. E., Davis, O. S. P., Helder, S., Bühren, K., Burghardt, R., de Zwaan, M., Egberts, K., Ehrlich, S., Herpertz-Dahlmann, B., Herzog, W., Imgart, H., Scherag, A., Scherag, S., Zipfel, S., Boni, C., Ramoz, N., Versini, A., Brandys, M. K., Danner, U. N., de Kove, C., Hendriks, J., Koeleman, B. P. C., Ophoff, R. A., Strengman, E., van Elburg, A. A., Bruson, A., Clementi, M., Degortes, D., Forzan, M., Tenconi, E., Docampo, E., Jiménez-Murcia, G. E. S., Lissowska, J., Rajewski, A., Szeszenia-Dabrowska, N., Slopien, A., Hauser, J., Karhunen, L., Meulenbelt, I., Slagboom, P. E., Tortorella, A., Maj, M., Dedoussis, G., Dikeos, D., Gonidakis, F., Tziouvas, K., Tsitsika, A., Papezova, H., Slachtova, L., Martaskova, D., Kennedy, J. L., Levitan, R. D., Yilmaz, Z., Huemer, J., Koubek, D., Merl, E., Wagner, G., Lichtenstein, P., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Cichon, S., Giegling, I., Herms, S., Rujescu, D., Schreiber, S., Wichmann, H. E., Christian, D., Sladek, R., Gambaro, G., Soranzo, N., Julia, A., Marsal, S., Rabionet, R., Gaborieau, V., Dick, D. M., Palotie, A., Ripatti, S., Widén, E., Andreassen, O. A., Espeseth, T., Lundervold, A., Reinvang, I., Steen, V. M., Le Hellard, S., Mattingsdal, M., Ntalla, I., Bencko, V., Foretova, L., Janout, V., Navratilova, M., Gallinger, S., Pinto, D., Scherer, S. W., Aschauer, H., Carlberg, L., Schosser, A., Alfredsson, L., Ding, B., Klareskog, L., Padyukov, L., Finan, C., Kalsi, G., Roberts, M., Logan, D. W., Peltonen, L., Ritchie, G. R. S., Barrett, J. C., Estivill, X., Hinney, A., Sullivan, P. F., Collier, D. A., Zeggini, E., Bulik, C. M., Anderson, C. A., Barrett, J. C., Floyd, J. A. B., Franklin, C. S., McGinnis, R., Soranzo, N., Zeggini, E., Sambrook, J., Stephens, J., Ouwehand, W. H., McArdle, W. L., Ring, S. M., Strachan, D. P., Alexander, G., Bulik, C. M., Collier, D. A., Conlon, P. J., Dominiczak, A., Duncanson, A., Hill, A., Langford, C., Lord, G., Maxwell, A. P., Morgan, L., Peltonen, L., Sandford, R. N., Sheerin, N., Vannberg, F. O., Blackburn, H., Chen, W. M., Edkins, S., Gillman, M., Gray, E., Hunt, S. E., Nengut, S. G., Potter, S., Rich, S. S., Simpkin, D., Whittaker, P., Adair, L. S., Ang, W., Atalay, M., van Beijsterveldt, T., Bergen, N., Benke, K., Berry, D. J., Boomsma, D. I., Bradfield, J. P., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Das, S., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Evans, D. M., Feenstra, B., Flexeder, C., Frayling, T., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M., Grant, S. F., Groen-Blokhuis, M., Goh, L. K., Guxens, M., Hakonarson, H., Hattersley, A. T., Haworth, C. M., Hadley, D., Hebebrand, J., Heinrich, J., Hinney, A., Hirschhorn, J. N., Hocher, B., Holloway, J. W., Holst, C., Hottenga, J. J., Horikoshi, M., Huikari, V., Hypponen, E., Iñiguez, C., Jaddoe, V. W., Jarvelin, M. R., Kaakinen, M., Kilpeläinen, T. O., Kirin, M., Kowgier, M., Lakka, H. M., Lakka, T. A., Lange, L. A., Lawlor, D. A., Lehtimäki, T., Lewin, A., Lindgren, C., Lindi, V., Maggi, R., Marsh, J., McCarthy, M. I., Melbye, M., Middeldorp, C., Millwood, I., Mohlke, K. L., Mook-Kanamori, D. O., Murray, J. C., Nivard, M., Nohr, E. A., Ntalla, I., Oken, E., Ong, K. K., O'Reilly, P. F., Palmer, L. J., Panoutsopoulou, K., Pararajasingham, J., Pearson, E. R., Pennell, C. E., Power, C., Price, T. S., Prokopenko, I., Raitakari, O. T., Rodriguez, A., Salem, R. M., Saw, S. M., Scherag, A., Sebert, S., Siitonen, N., Simell, O., Sørensen, T. I., Sovio, U., Pourcain, B. S., Strachan, D. P., Sunyer, J., Taal, H. R., Teo, Y. Y., Thiering, E., Tiesler, C., Timpson, N. J., Uitterlinden, A. G., Valcárcel, B., Warrington, N. M., White, S., Widén, E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zeggini, E., Elks, C. E., Perry, J. R., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Byrne, E. M., Cousminer, D. L., Gudbjartsson, D. F., Esko, T., Feenstra, B., Hottenga, J. J., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S. H., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K., Smith, E. N., Ulivi, S., Warrington, M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Coviello, A. D., d'Adamo, P., de Faire, U., de Geus, E. J., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Eriksson, J., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Geller, F., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hofman, A., Hu, F. B., Illig, T., Järvelin, M. R., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kilpeläinen, T. O., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., Martin, N. G., McArdle, W. L., Melbye, M., Mooser, V., Murray, J. C., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Palmer, L. J., Palotie, A., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Pouta, A., Porcu, E., Rafnar, T., Rice, J. P., Ring, S. M., Rivadeneira, F., Rudan, I., Sala, C., Salomaa, V., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V., Shuldiner, A. R., Soranzo, N., Sovio, U., Srinivasan, S. R., Strachan, D. P., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., van Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D. M., Weedon, M. N., Wichmann, H. E., Willemsen, G., Wilson, J. F., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Montgomery, G. W., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Uitterlinden, A. G., Widen, E., Murabito, J. M., Ong, K. K., Murray, A., Brandt, H., Crawford, S., Crow, S., Fichter, M. M., Halmi, K. A., Johnson, C., Kaplan, A. S., La Via, M., Mitchell, J., Strober, M., Rotondo, A., Treasure, J., Woodside, D. B., Bulik, C. M., Keel, P., Klump, K. L., Lilenfeld, L., Thornton, L. M., Plotnicov, K., Bergen, A. W., Berrettini, W., Kaye, W. & Magistretti, P. 1 Feb 2017 In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

    Research output: Contribution to journalArticle

  36. The Genetic Architecture of Gene Expression in Peripheral Blood

    Lloyd-Jones, L. R., Holloway, A., McRae, A., Yang, J., Small, K., Zeng, B., Bakshi, A., Metspalu, A., Dermitzakis, M., Gibson, G., Spector, T., Montgomery, G., Esko, T., Visscher, P. M. & Powell, J. E. Feb 2017 In : American Journal of Human Genetics.

    Research output: Contribution to journalArticle

  37. MixFit: Methodology for computing ancestry-related genetic scores at the individual level and its application to the estonian and finnish population studies

    Haller, T., Leitsalu, L., Fischer, K., Nuotio, M. L., Esko, T., Boomsma, D. I., Kyvik, K. O., Spector, T. D., Perola, M. & Metspalu, A. 20 Jan 2017 In : PL o S One . 12, 1, e0170325

    Research output: Contribution to journalArticle

  38. Innate and adaptive immune traits are differentially affected by genetic and environmental factors

    Mangino, M., Roederer, M., Beddall, M. H., Nestle, F. O. & Spector, T. D. 5 Jan 2017 In : Nature Communications. 8, 13850

    Research output: Contribution to journalArticle

  39. Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study

    De Vries, P. S. , Sabater-Lleal, M. , Chasman, D. I. , Trompet, S. , Ahluwalia, T. S. , Teumer, A. , Kleber, M. E. , Chen, M. H. , Wang, J. J. , Attia, J. R. , Marioni, R. E. , Steri, M. , Weng, L. C. , Pool, R. , Grossmann, V. , Brody, J. A. , Venturini, C. , Tanaka, T. , Rose, L. M. , Oldmeadow, C. & 66 others Mazur, J., Basu, S., Frånberg, M., Yang, Q., Ligthart, S., Hottenga, J. J., Rumley, A., Mulas, A., De Craen, A. J. M., Grotevendt, A., Taylor, K. D., Delgado, G. E., Kifley, A., Lopez, L. M., Berentzen, T. L., Mangino, M., Bandinelli, S., Morrison, A. C., Hamsten, A., Tofler, G., De Maat, M. P. M., Draisma, H. H. M., Lowe, G. D., Zoledziewska, M., Sattar, N., Lackner, K. J., Völker, U., McKnight, B., Huang, J., Holliday, E. G., McEvoy, M. A., Starr, J. M., Hysi, P. G., Hernandez, D. G., Guan, W., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Psaty, B. M., Uitterlinden, A. G., De Geus, E. J. C., Stott, D. J., Binder, H., Hofman, A., Franco, O. H., Rotter, J. I., Ferrucci, L., Spector, T. D., Deary, I. J., März, W., Greinacher, A., Wild, P. S., Cucca, F., Boomsma, D. I., Watkins, H., Tang, W., Ridker, P. M., Jukema, J. W., Scott, R. J., Mitchell, P., Hansen, T., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A. 1 Jan 2017 In : PL o S One . 12, 1, e0167742

    Research output: Contribution to journalArticle

  40. Positive Association Between Vitamin D Serum Levels and Naevus Counts

    Ribero, S., Glass, D., Mangino, M., Aviv, A., Spector, T. & Bataille, V. 1 Jan 2017 In : Acta Dermato-Venereologica. 97, 3, p. 321-324

    Research output: Contribution to journalArticle

  41. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

    Wain, L. V. , Vaez, A. , Jansen, R. , Joehanes, R. , van der Most, P. J. , Erzurumluoglu, A. M. , O'Reilly, P. F. , Cabrera, C. P. , Warren, H. R. , Rose, L. M. , Verwoert, G. C. , Hottenga, J-J. , Strawbridge, R. J. , Esko, T. , Arking, D. E. , Hwang, S-J. , Guo, X. , Kutalik, Z. , Trompet, S. , Shrine, N. & 223 others Teumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikäinen, L-P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sõber, S., Vuckovic, D., Luan, J., Del Greco M., F., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Jackson, A. U., Nelson, C. P., Huffman, J. E., Zhang, W., Marten, J., Gandin, I., Harris, S. E., Zemunik, T., Lu, Y., Evangelou, E., Shah, N., de Borst, M. H., Mangino, M., Prins, B. P., Campbell, A., Li-Gao, R., Chauhan, G., Oldmeadow, C., Abecasis, G., Abedi, M., Barbieri, C. M., Barnes, M. R., Batini, C., Beilby, J., Blake, T., Boehnke, M., Bottinger, E. P., Braund, P. S., Brown, M., Brumat, M., Campbell, H., Chambers, J. C., Cocca, M., Collins, F., Connell, J., Cordell, H. J., Damman, J. J., Davies, G., de Geus, E. J., de Mutsert, R., Deelen, J., Demirkale, Y., Doney, A. S. F., Dörr, M., Farrall, M., Ferreira, T., Frr anberg, M., Gao, H., Giedraitis, V., Gieger, C., Giulianini, F., Gow, A. J., Hamsten, A., Harris, T. B., Hofman, A., Holliday, E. G., Hui, J., Jarvelin, M-R., Johansson, R. A., Johnson, A. D., Jousilahti, P., Jula, A., Kähönen, M., Kathiresan, S., Khaw, K-T., Kolcic, I., Koskinen, S., Langenberg, C., Larson, M., Launer, L. J., Lehne, B., Liewald, D. C. M., Lin, L., Lind, L., Mach, F., Mamasoula, C., Menni, C., Mifsud, B., Milaneschi, Y., Morgan, A., Morris, A. D., Morrison, A. C., Munson, P. J., Nandakumar, P., Nguyen, Q. T., Nutile, T., Oldehinkel, A. J., Oostra, B. A., Org, E., Padmanabhan, S., Palotie, A., Paré, G., Pattie, A., Penninx, B. W. J. H., Poulter, N., Pramstaller, P. P., Raitakari, O. T., Ren, M., Rice, K., Ridker, P. M., Riese, H., Ripatti, S., Robino, A., Rotter, J. I., Rudan, I., Saba, Y., Saint Pierre, A., Sala, C. F., Sarin, A-P., Schmidt, R., Scott, R., Seelen, M. A., Shields, D. C., Siscovick, D., Sorice, R., Stanton, A., Stott, D. J., Sundström, J., Swertz, M., Taylor, K. D., Thom, S., Tzoulaki, I., Tzourio, C., Uitterlinden, A. G., Völker, U., Vollenweider, P., Wild, S., Willemsen, G., Wright, A. F., Yao, J., Thériault, S., Conen, D., Attia, J., Sever, P., Debette, S., Mook-Kanamori, D. O., Zeggini, E., Spector, T. D., van der Harst, P., Palmer, C. N. A., Vergnaud, A-C., Loos, R. J. F., Polasek, O., Starr, J. M., Girotto, G., Hayward, C., Kooner, J. S., Lindgren, C. M., Vitart, V., Samani, N. J., Tuomilehto, J., Gyllensten, U., Knekt, P., Deary, I. J., Ciullo, M., Elosua, R., Keavney, B. D., Hicks, A. A., Scott, R. A., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, C. A., Salomaa, V., Toniolo, D., Perola, M., Wilson, J. F., Schmidt, H., Zhao, J. H., Lehtimäki, T., van Duijn, C. M., Gudnason, V., Psaty, B. M., Peters, A., Rettig, R., James, A., Jukema, J. W., Strachan, D. P., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, D. I., Franco, O. H., Bochud, M., Newton-Cheh, C., Munroe, P. B., Elliott, P., Chasman, D. I., Chakravarti, A., Knight, J., Morris, A. P., Levy, D., Tobin, M. D., Snieder, H., Caulfield, M. J. & Ehret, G. B. 2017 In : Hypertension. 70, 3, p. e4-e19

    Research output: Contribution to journalArticle

  42. 2016
  43. Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome

    Xie, H. , Guo, R. , Zhong, H. , Feng, Q. , Lan, Z. , Qin, B. , Ward, K. J. , Jackson, M. A. , Xia, Y. , Chen, X. , Chen, B. , Xia, H. , Xu, C. , Li, F. , Xu, X. , Al-Aama, J. Y. , Yang, H. , Wang, J. , Kristiansen, K. , Wang, J. & 5 others Steves, C. J., Bell, J. T., Li, J., Spector, T. D. & Jia, H. 21 Dec 2016 In : Cell Systems. 3, 6, p. 572-584.e3

    Research output: Contribution to journalArticle

  44. Higher Naevus Count Exhibits A Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma

    Roos, L., Sandling, J. K., Bell, C. G., Glass, D., Mangino, M., Spector, T. D., Deloukas, P., Bataille, V. & Bell, J. T. 18 Dec 2016 In : Journal of Investigative Dermatology.

    Research output: Contribution to journalArticle

  45. Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994

    Jelenkovic, A. , Hur, Y-M. , Sund, R. , Yokoyama, Y. , Siribaddana, S. H. , Hotopf, M. , Sumathipala, A. , Rijsdijk, F. , Tan, Q. , Zhang, D. , Pang, Z. , Aaltonen, S. , Heikkilä, K. , Öncel, S. Y. , Aliev, F. , Rebato, E. , Tarnoki, A. D. , Tarnoki, D. L. , Christensen, K. , Skytthe, A. & 80 others Kyvik, K. O., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Cozen, W., Hwang, A. E., Mack, T. M., Sung, J., Song, Y-M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H-U., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl-Aslan, A. K., McAdams, T., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Lichtenstein, P., Spector, T. D., Mangino, M., Lachance, G., Bartels, M., van Beijsterveldt, T. C. E. M., Willemsen, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Hjelmborg, J. V. B., Goldberg, J. H., Iwatani, Y., Watanabe, M., Honda, C., Inui, F., Rasmussen, F., Huibregtse, B. M., Boomsma, D. I., Sørensen, T. I. A., Kaprio, J., Silventoinen, K. & Franco, E. (ed.) 14 Dec 2016 In : eLife. 5, p. e20320

    Research output: Contribution to journalArticle

  46. Autosomal genetic control of human gene expression does not differ across the sexes

    Kassam, I., Lloyd-Jones, L., Holloway, A., Small, K. S., Zeng, B., Bakshi, A., Metspalu, A., Gibson, G., Spector, T. D., Esko, T., Montgomery, G. W., Powell, J. E., Yang, J., Visscher, P. M. & McRae, A. F. 1 Dec 2016 In : Genome Biology. 17, 1, 248

    Research output: Contribution to journalArticle

  47. KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

    Schumann, G. , Liu, C. , O'Reilly, P. , Gao, H. , Song, P. , Xu, B. , Ruggeri, B. , Amin, N. , Jia, T. , Preis, S. , Segura Lepe, M. , Akira, S. , Barbieri, C. , Baumeister, S. , Cauchi, S. , Clarke, T-K. , Enroth, S. , Fischer, K. , Hällfors, J. , Harris, S. E. & 107 others Hieber, S., Hofer, E., Hottenga, J-J., Johansson, Å., Joshi, P. K., Kaartinen, N., Laitinen, J., Lemaitre, R., Loukola, A., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Mbarek, H., Milaneschi, Y., Moayyeri, A., Mukamal, K., Nelson, C., Nettleton, J., Partinen, E., Rawal, R., Robino, A., Rose, L., Sala, C., Satoh, T., Schmidt, R., Schraut, K., Scott, R., Smith, A. V., Starr, J. M., Teumer, A., Trompet, S., Uitterlinden, A. G., Venturini, C., Vergnaud, A-C., Verweij, N., Vitart, V., Vuckovic, D., Wedenoja, J., Yengo, L., Yu, B., Zhang, W., Zhao, J. H., Boomsma, D. I., Chambers, J., Chasman, D. I., Daniela, T., de Geus, E., Deary, I., Eriksson, J. G., Esko, T., Eulenburg, V., Franco, O. H., Froguel, P., Gieger, C., Grabe, H. J., Gudnason, V., Gyllensten, U., Harris, T. B., Hartikainen, A-L., Heath, A. C., Hocking, L., Hofman, A., Huth, C., Jarvelin, M-R., Jukema, J. W., Kaprio, J., Kooner, J. S., Kutalik, Z., Lahti, J., Langenberg, C., Lehtimäki, T., Liu, Y., Madden, P. A. F., Martin, N., Morrison, A., Penninx, B., Pirastu, N., Psaty, B., Raitakari, O., Ridker, P., Rose, R., Rotter, J. I., Samani, N. J., Schmidt, H., Spector, T. D., Stott, D., Strachan, D., Tzoulaki, I., van der Harst, P., van Duijn, C. M., Marques-Vidal, P., Vollenweider, P., Wareham, N. J., Whitfield, J. B., Wilson, J., Wolffenbuttel, B., Bakalkin, G., Evangelou, E., Liu, Y., Rice, K. M., Desrivières, S., Kliewer, S. A., Mangelsdorf, D. J., Müller, C. P., Levy, D. & Elliott, P. 28 Nov 2016 In : Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalArticle

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