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Research Outputs

  1. 2022
  2. Acceptability of point of care testing for antipsychotic medication levels in schizophrenia

    Atkins, M., Taylor, D., Harland, R., Brewer, A., Williams, S., Chesney, E. & McGuire, P., 1 Dec 2022, In: Psychiatry Research Communications. 100070.

    Research output: Contribution to journalArticlepeer-review

  3. Examining the variability of neurocognitive functioning in individuals at clinical high risk for psychosis: a meta-analysis

    Catalan, A., Radua, J., McCutcheon, R., Aymerich, C., Pedruzo, B., González-Torres, M. Á., Baldwin, H., Stone, W. S., Giuliano, A. J., McGuire, P. & Fusar-Poli, P., Dec 2022, In: Translational psychiatry. 12, 1, 198.

    Research output: Contribution to journalReview articlepeer-review

  4. Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios

    Englund, A., Oliver, D., Chesney, E., Chester, L., Wilson, J., Sovi, S., Andrea, D. M., Hodsoll, J., Fusar-Poli, P., Strang, J., Murray, R., Freeman, T. P. & McGuire, P., 10 Oct 2022, (Accepted/In press) In: Neuropsychopharmacology.

    Research output: Contribution to journalArticlepeer-review

  5. Effects of cannabidiol and delta-9-tetrahydrocannabinol on plasma endocannabinoid levels in healthy volunteers: a randomised double-blind four-arm cross-over study

    Chester, L., Englund, A., Chesney, E., Oliver, D., Wilson, J., Sovi, S., Dickens, A. M., Oresic, M., Linderman, T., Hodsoll, J., Minichino, A., Strang, J., Murray, R., Freeman, T. P. & McGuire, P., 10 Oct 2022, (Accepted/In press) In: Cannabis and cannabinoid research.

    Research output: Contribution to journalArticlepeer-review

  6. The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia

    Kaar, S. J., Angelescu, I., Nour, M. M., Marques, T. R., Sharman, A., Sajjala, A., Hutchinson, J., McGuire, P., Large, C. & Howes, O. D., Oct 2022, In: Psychopharmacology. 239, 10, p. 3313-3323 11 p.

    Research output: Contribution to journalArticlepeer-review

  7. Evaluating physical urban features in several mental illnesses using electronic health record data

    Mahabadi, Z., Mahabadi, M., Velupillai, S., Roberts, A., McGuire, P., Ibrahim, Z. & Patel, R., 7 Sep 2022, In: Frontiers in digital health. 4, 874237.

    Research output: Contribution to journalArticlepeer-review

  8. Hippocampal circuit dysfunction in psychosis

    Knight, S., McCutcheon, R., Dwir, D., Grace, A. A., O'Daly, O., McGuire, P. & Modinos, G., 25 Aug 2022, (E-pub ahead of print) In: Translational psychiatry.

    Research output: Contribution to journalReview articlepeer-review

  9. Meta-Analysis of longitudinal neurocognitive performance in people at clinical high-risk for psychosis

    Hedges, E. P., See, C., Si, S., McGuire, P., Dickson, H. & Kempton, M. J., 13 Aug 2022, In: Psychological Medicine. 52, 11, p. 2009-2016 8 p.

    Research output: Contribution to journalReview articlepeer-review

  10. Relaxation of the criteria for entry to the UK Clozapine Central Non-Rechallenge Database: a modelling study

    Oloyede, E., Whiskey, E., Casetta, C., Dzahini, O., Dunnett, D., Gandhi, S., Gaughran, F., Shergill, S., McGuire, P., MacCabe, J. H. & Taylor, D., Aug 2022, In: The Lancet Psychiatry. 9, 8, p. 636-644 9 p.

    Research output: Contribution to journalArticlepeer-review

  11. Differential trajectories of tobacco smoking in people at ultra-high risk for psychosis: Associations with clinical outcomes

    EU-GEI High Risk Study Group, 22 Jul 2022, In: Frontiers in Psychiatry. 13, p. 869023 869023.

    Research output: Contribution to journalArticlepeer-review

  12. Impaired verbal memory function is related to anterior cingulate glutamate levels in schizophrenia: findings from the STRATA study

    Griffiths, K., Egerton, A., Millgate, E., Anton, A., Barker, G. J., Deakin, B., Drake, R., Eliasson, E., Gregory, C. J., Howes, O. D., Kravariti, E., Lawrie, S. M., Lewis, S., Lythgoe, D. J., Murphy, A., McGuire, P., Semple, S., Stockton-Powdrell, C., Walters, J. T. R., Williams, S. R., & 1 othersMacCabe, J. H., 12 Jul 2022, In: Schizophrenia. 8, 1, p. 60 60.

    Research output: Contribution to journalArticlepeer-review

  13. The enduring gap in educational attainment in schizophrenia according to the past 50 years of published research: a systematic review and meta-analysis

    Crossley, N. A., Alliende, L. M., Czepielewski, L. S., Aceituno, D., Castañeda, C. P., Diaz, C., Iruretagoyena, B., Mena, C., Mena, C., Ramirez-Mahaluf, J. P., Tepper, A., Vasquez, J., Fonseca, L., Machado, V., Hernández, C. E., Vargas-Upegui, C., Gomez-Cruz, G., Kobayashi-Romero, L. F., Moncada-Habib, T., Arango, C., & 14 othersBarch, D. M., Carter, C., Correll, C. U., Freimer, N. B., McGuire, P., Evans-Lacko, S., Undurraga, E., Bressan, R., Gama, C. S., Lopez-Jaramillo, C., de la Fuente-Sandoval, C., Gonzalez-Valderrama, A., Undurraga, J. & Gadelha, A., 1 Jul 2022, In: The Lancet Psychiatry. 9, 7, p. 565-573 9 p.

    Research output: Contribution to journalArticlepeer-review

  14. Graph convolutional networks reveal network-level functional dysconnectivity in schizophrenia

    Lei, D., Qin, K., Pinaya, W. H. L., Young, J., Van Amelsvoort, T., Marcelis, M., Donohoe, G., Mothersill, D. O., Corvin, A., Vieira, S., Lui, S., Scarpazza, C., Arango, C., Bullmore, E., Gong, Q., McGuire, P. & Mechelli, A., Jul 2022, In: Schizophrenia Bulletin. 48, 4, p. 881–892 12 p.

    Research output: Contribution to journalArticlepeer-review

  15. Scalability of the Positive and Negative Syndrome Scale in first-episode schizophrenia assessed by Rasch models

    Baandrup, L., Allerup, P., Nielsen, M., Düring, S. W., Bojesen, K. B., Leucht, S., Galderisi, S., Mucci, A., Bucci, P., Arango, C., Díaz-Caneja, C. M., Dazzan, P., McGuire, P., Demjaha, A., Ebdrup, B. H., Fleischhacker, W. W., Kahn, R. S. & Glenthøj, B. Y., Jul 2022, In: Acta Psychiatrica Scandinavica. 146, 1, p. 21-35 15 p.

    Research output: Contribution to journalArticlepeer-review

  16. The relationship between grey matter volume and clinical and functional outcomes in people at clinical high risk for psychosis

    EU-GEI High Risk Study*, 10 Jun 2022, (Accepted/In press) In: Schizophrenia Bulletin Open.

    Research output: Contribution to journalArticlepeer-review

  17. Prognostic accuracy and clinical utility of psychometric instruments for individuals at clinical high-risk of psychosis: a systematic review and meta-analysis.

    Oliver, D., Arribas, M., Radua, J., Salazar de Pablo, G., De Micheli, A., Spada, G., Mensi, M. M., Kotlicka-Antczak, M., Borgatti, R., Solmi, M., Jae Il Shin, FRCP., Woods, S. W., Addington, J., McGuire, P. & Fusar-Poli, P., 3 Jun 2022, In: Molecular Psychiatry. 27, 9, p. 3670-3678 9 p.

    Research output: Contribution to journalArticlepeer-review

  18. Cariprazine as a treatment for negative psychotic symptoms in first-episode psychosis: Case series

    Demjaha, A., Iacoponi, E., Hansen, L., Peddu, P. & McGuire, P., 28 May 2022, In: BJPsych Open. 8, 3, e88.

    Research output: Contribution to journalArticlepeer-review

  19. Examining the variability of neurocognitive functioning in individuals at clinical high risk for psychosis: a meta-analyses.

    Catalan Alcantara, A., McCutcheon, R., Aymerich, C., Pedruzo, B., Gonzalez-Torres, M. A., Baldwin, H., Stone, W. S., Giuliano, A. J., McGuire, P. & Fusar-Poli, P., 27 Apr 2022, (Accepted/In press) In: Translational psychiatry.

    Research output: Contribution to journalArticlepeer-review

  20. Brain charts for the human lifespan

    3R-BRAIN, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, CALM Team, Cam-CAN, CCNP, COBRE, cVEDA, ENIGMA Developmental Brain Age Working Group, Developing Human Connectome Project, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, Mayo Clinic Study of Aging, NSPN, POND, PREVENT-AD Research Group & VETSA, 21 Apr 2022, In: Nature. 604, 7906, p. 525-533 9 p.

    Research output: Contribution to journalArticlepeer-review

  21. Psychosis and Substance Abuse increase the COVID-19 mortality risk

    Catalan, A., Aymerich, C., Bilbao, A., Pedruzo, B., Pérez, J. L., Aranguren, N., Salazar de Pablo, G., Hedges, E., Gil, P., Segarra, R., González-Pinto, A., Fernández-Rivas, A., Inchausti, L., Mcguire, P., Fusar-Poli, P. & González-Torres, M. Á., 12 Apr 2022, (E-pub ahead of print) In: Psychological medicine. p. 1-9

    Research output: Contribution to journalArticlepeer-review

  22. Reinventing schizophrenia: The rules of the game

    McCutcheon, R. A. & McGuire, P., Apr 2022, In: Schizophrenia Research. 242, p. 94-95 2 p.

    Research output: Contribution to journalArticlepeer-review

  23. Negative symptoms in First-Episode Schizophrenia related to morphometric alterations in orbitofrontal and superior temporal cortex: The OPTiMiSE study

    Demjaha, A., Galderisi, S., Glenthøj, B., Arango, C., Mucci, A., Lawrence, A., O'Daly, O., Kempton, M., Ciufolini, S., Baandrup, L., Ebdrup, B. H., Rodriguez-Jimenez, R., Diaz-Marsa, M., Díaz-Caneja, C. M., Winter Van Rossum, I., Kahn, R., Dazzan, P. & McGuire, P., 24 Feb 2022, (E-pub ahead of print) In: Psychological Medicine.

    Research output: Contribution to journalArticlepeer-review

  24. Identifying electroencephalography (EEG) biomarkers in individuals at clinical high risk for psychosis in an international multi-site study

    Kerins, S., Nottage, J., Salazar de Pablo, G., Kempton, M., Tognin, S., Niemann, D. H., De Haan, L., Van Amelsvoort, T., Kwon, J. S., Nelson, B., Mizrahi, R., McGuire, P., Fusar-Poli, P. & and the PSYSCAN Consortium, 10 Feb 2022, (Accepted/In press) In: Frontiers in Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  25. Clinical outcomes in individuals at clinical high risk of psychosis who do not transition to psychosis: a meta-analysis

    Salazar de pablo, G., Soardo, L., Cabras, A., Pereira, J., Kaur, S., Besana, F., Arienti, V., Coronelli, F., Shin, J. I., Solmi, M., Petros, N., Carvalho, A. F., Mcguire, P. & Fusar-Poli, P., 19 Jan 2022, In: Epidemiology And Psychiatric Sciences. 31, e9.

    Research output: Contribution to journalArticlepeer-review

  26. Cortisol Levels in Childhood Associated with Emergence of Attenuated Psychotic Symptoms in Early Adulthood

    Cullen, A., Fisher, H., Gullett, N., Fraser, E., Roberts, R. E., Zahid, U., To, M., Yap, N., Zunszain, P., Pariante, C., Wood, S., McGuire, P., Murray, R., Mondelli, V. & Laurens, K. R., 15 Jan 2022, In: Biological psychiatry. 91, 2, p. 226-235 10 p.

    Research output: Contribution to journalArticlepeer-review

  27. Ethical considerations for precision psychiatry: a roadmap for research and clinical practice

    Fusar-Poli, P., Manchia, M., Koutsouleris, N., McGuire, P., Leslie, D., Woopen, C., Le Tourneau, C., Mollemma, T., Oliver, D., Rietschel, M., Reininghaus, E. Z., Squassina, A., Valmaggia, L., Kessing, L. V., Vieta, E., Correll, C. U., Arango, C. & Andreassen, O., 2022, (Accepted/In press) In: European Neuropsychopharmacology.

    Research output: Contribution to journalArticlepeer-review

  28. Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited

    Koutsouleris, N., Pantelis, C., Velakoulis, D., Mcguire, P., Dwyer, D. B., Urquijo-Castro, M. F., Paul, R., Dong, S., Popovic, D., Oeztuerk, O., Kambeitz, J., Salokangas, R. K. R., Hietala, J., Bertolino, A., Brambilla, P., Upthegrove, R., Wood, S. J., Lencer, R., Borgwardt, S., Maj, C., & 21 othersNöthen, M., Degenhardt, F., Polyakova, M., Mueller, K., Villringer, A., Danek, A., Fassbender, K., Fliessbach, K., Jahn, H., Kornhuber, J., Landwehrmeyer, B., Anderl-Straub, S., Prudlo, J., Synofzik, M., Wiltfang, J., Riedl, L., Diehl-Schmid, J., Otto, M., Meisenzahl, E., Falkai, P. & Schroeter, M. L., 2022, (Accepted/In press) In: JAMA Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  29. 2021
  30. Effect of Vitamin D Supplementation on Outcomes in People With Early Psychosis: The DFEND Randomized Clinical Trial

    Gaughran, F., Stringer, D., Wojewodka, G., Landau, S., Smith, S., Gardner-Sood, P., Taylor, D., Jordan, H., Whiskey, E., Krivoy, A., Ciufolini, S., Stubbs, B., Casetta, C., Williams, J., Moore, S., Allen, L., Rathod, S., Boardman, A., Khalifa, R., Firdosi, M., & 3 othersMcGuire, P., Berk, M. & McGrath, J., 28 Dec 2021, In: JAMA Network open. 4, 12, p. e2140858

    Research output: Contribution to journalArticlepeer-review

  31. Natural Language Processing markers in first episode psychosis and people at clinical high-risk

    Morgan, S. E., Diederen, K., Vértes, P. E., Ip, S. H. Y., Wang, B., Thompson, B., Demjaha, A., De Micheli, A., Oliver, D., Liakata, M., Fusar-Poli, P., Spencer, T. J. & McGuire, P., 13 Dec 2021, In: Translational psychiatry. 11, 1, 630.

    Research output: Contribution to journalArticlepeer-review

  32. Across the continuum: Associations between (fluctuations in) momentary self-esteem and psychotic experiences

    Postma, M. R., van Amelsvoort, T., Myin-Germeys, I., Gayer-Anderson, C., Kempton, M. J., Valmaggia, L., McGuire, P., Murray, R. M., Garety, P., Wykes, T., Morgan, C. & Reininghaus, U., Dec 2021, In: Schizophrenia Research. 238, p. 188-198 11 p.

    Research output: Contribution to journalArticlepeer-review

  33. Proportion and predictors of remission and recovery in first-episode psychosis: Systematic review and meta-analysis

    Catalan, A., Richter, A., Salazar De Pablo, G., Vaquerizo-Serrano, J., Mancebo, G., Pedruzo, B., Aymerich, C., Solmi, M., González-Torres, M. A., Gil, P., Mcguire, P. & Fusar-Poli, P., 3 Nov 2021, In: European Psychiatry. 64, 1, e69.

    Research output: Contribution to journalReview articlepeer-review

  34. Primary prevention of depression: An umbrella review of controlled interventions

    Salazar de Pablo, G., Solmi, M., Vaquerizo-Serrano, J., Radua, J., Passina, A., Morsillo, P., Correll, C. U., Borgwardt, S., Galderisi, S., Bechdolf, A., Pfennig, A., Bauer, M., Kessing, L. V., van Amelsvoort, T., Nieman, D. H., Domschke, K., Krebs, M. O., Sand, M., Vieta, E., McGuire, P., & 3 othersArango, C., Shin, J. I. & Fusar-Poli, P., 1 Nov 2021, In: Journal of Affective Disorders. 294, p. 957-970 14 p.

    Research output: Contribution to journalReview articlepeer-review

  35. Toward Generalizable and Transdiagnostic Tools for Psychosis Prediction: An Independent Validation and Improvement of the NAPLS-2 Risk Calculator in the Multisite PRONIA Cohort

    Koutsouleris, N., Worthington, M., Dwyer, D. B., Kambeitz-Ilankovic, L., Sanfelici, R., Fusar-Poli, P., Rosen, M., Ruhrmann, S., Anticevic, A., Addington, J., Perkins, D. O., Bearden, C. E., Cornblatt, B. A., Cadenhead, K. S., Mathalon, D. H., McGlashan, T., Seidman, L., Tsuang, M., Walker, E. F., Woods, S. W., & 15 othersFalkai, P., Lencer, R., Bertolino, A., Kambeitz, J., Schultze-Lutter, F., Meisenzahl, E., Salokangas, R. K. R., Hietala, J., Brambilla, P., Upthegrove, R., Borgwardt, S., Wood, S., Gur, R. E., McGuire, P. & Cannon, T. D., 1 Nov 2021, In: Biological psychiatry. 90, 9, p. 632-642 11 p.

    Research output: Contribution to journalArticlepeer-review

  36. Momentary manifestations of negative symptoms as predictors of clinical outcomes in people at high risk for psychosis: Experience sampling study

    Paetzold, I., Hermans, K. S. F. M., Schick, A., Nelson, B., Velthorst, E., Schirmbeck, F., van Os, J., Morgan, C., van der Gaag, M., de Haan, L., Valmaggia, L., McGuire, P., Kempton, M., Myin-Germeys, I. & Reininghaus, U., Nov 2021, In: JMIR Mental Health. 8, 11, e30309.

    Research output: Contribution to journalArticlepeer-review

  37. Verbal memory performance predicts remission and functional outcome in people at clinical high-risk for psychosis

    Hedges, E., Dickson, H., Tognin, S., Modinos, G., Antoniades, M., van der Gaag, M., de Haan, L., McGorry, P., Pantelis, C., Riecher-Rossler, A., Bressan, R., Barrantes-Vidal, N., Krebs, M-O., Nordentoft, M., Ruhrmann, S., Sachs, G., Rutten, B., van Os, J., EU-GEI High Risk Study, Valmaggia, L., & 2 othersMcGuire, P. & Kempton, M., 11 Oct 2021, (Accepted/In press) In: Schizophrenia Research: Cognition.

    Research output: Contribution to journalArticlepeer-review

  38. Association between tobacco use and symptomatology in individuals at ultra-high risk to develop a psychosis: A longitudinal study

    EU-GEI High Risk Study, Oct 2021, In: Schizophrenia Research. 236, p. 48-53 6 p.

    Research output: Contribution to journalArticlepeer-review

  39. Impact of Comorbid Affective Disorders on Longitudinal Clinical Outcomes in Individuals at Ultra-high Risk for Psychosis

    EU-GEI High Risk Study Group Authors , 21 Aug 2021, In: Schizophrenia Bulletin.

    Research output: Contribution to journalArticlepeer-review

  40. Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings

    EU-GEI High Risk Study, Aug 2021, In: Molecular Psychiatry. 26, 8, p. 4529-4543 15 p.

    Research output: Contribution to journalArticlepeer-review

  41. Neurocognitive Functioning in Individuals at Clinical High Risk for Psychosis: A Systematic Review and Meta-analysis

    Catalan, A., Salazar De Pablo, G., Aymerich, C., Damiani, S., Sordi, V., Radua, J., Oliver, D., McGuire, P., Giuliano, A. J., Stone, W. S. & Fusar-Poli, P., Aug 2021, In: JAMA Psychiatry. 78, 8, p. 859-867 9 p.

    Research output: Contribution to journalReview articlepeer-review

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