King's College London

Research portal

Research Outputs

  1. 2021
  2. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Jun 2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.

    Research output: Contribution to journalArticlepeer-review

  3. Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

    Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S., Giusti-Rodríguez, P. & 30 others, Hanscombe, K. B., Adan, R. A. H., Alfredsson, L., Ando, T., Andreassen, O. A., Berrettini, W. H., Boehm, I., Boni, C., Boraska Perica, V., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Farmer, A., Helder, S. G., Kalsi, G., McGuffin, P., Roberts, M., Schmidt, U., Treasure, J., Walton, E., Lynskey, M. T., Madden, P. A. F., Riley, B. P., Neale, B. M. & Breen, G., Jan 2021, In: Addiction Biology. 26, 1, e12880.

    Research output: Contribution to journalArticlepeer-review

  4. A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

    Schizophrenia Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Nov 2021, In: Biological psychiatry. 90, 9, p. 611-620 10 p.

    Research output: Contribution to journalArticlepeer-review

  5. Genome-wide association study of suicidal behaviour severity in mood disorders

    Zai, C. C., Fabbri, C., Hosang, G. M., Zhang, R. S., Koyama, E., de Luca, V., Tiwari, A. K., King, N., Strauss, J., Jones, I., Jones, L., Breen, G., Farmer, A. E., McGuffin, P., Vincent, J. B., Kennedy, J. L. & Lewis, C. M., 2021, (Accepted/In press) In: World Journal of Biological Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  6. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder

    Jia, X., Goes, F. S., Locke, A. E., Palmer, D., Wang, W., Cohen-Woods, S., Genovese, G., Jackson, A. U., Jiang, C., Kvale, M., Mullins, N., Nguyen, H., Pirooznia, M., Rivera, M., Ruderfer, D. M., Shen, L., Thai, K., Zawistowski, M., Zhuang, Y., Abecasis, G. & 56 others, Akil, H., Bergen, S., Burmeister, M., Champion, S., DelaBastide, M., Juréus, A., Kang, H. M., Kwok, P. Y., Li, J. Z., Levy, S. E., Monson, E. T., Moran, J., Sobell, J., Watson, S., Willour, V., Zöllner, S., Adolfsson, R., Blackwood, D., Boehnke, M., Breen, G., Corvin, A., Craddock, N., DiFlorio, A., Hultman, C. M., Landen, M., Lewis, C., McCarroll, S. A., Richard McCombie, W., McGuffin, P., McIntosh, A., McQuillin, A., Morris, D., Myers, R. M., O’Donovan, M., Ophoff, R., Boks, M., Kahn, R., Ouwehand, W., Owen, M., Pato, C., Pato, M., Posthuma, D., Potash, J. B., Reif, A., Sklar, P., Smoller, J., Sullivan, P. F., Vincent, J., Walters, J., Neale, B., Purcell, S., Risch, N., Schaefer, C., Stahl, E. A., Zandi, P. P. & Scott, L. J., 2021, (Accepted/In press) In: Molecular Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  7. 2020
  8. The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

    Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 15 Jul 2020, In: Biological psychiatry. 88, 2, p. 169-184 16 p.

    Research output: Contribution to journalArticlepeer-review

  9. Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

    Eating Disorders Working Group of the Psychiatric Genomics Consortium, International Headache Genetics Consortium, 23andMe Research Team & Schmidt, U., 1 May 2020, In: Nature Genetics. 52, 5, p. 482-493 12 p.

    Research output: Contribution to journalArticlepeer-review

  10. Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

    Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K., Breen, G., Air, T. M., Andlauer, T. M. F., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., de Geus, E. J. C. & 34 others, Grabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Lucae, S., Magnusson., P. K. E., McGuffin, P., McIntosh, A., Milaneschi, Y., Lewis, C. M., Mostafavi, S., Muller-Myhsok, B., Pedersen, N. L., Penninx, B. W., Potash, J. B., Preisig, M., Ripke, S., Shi, J., Shyn, S. I., Smoller, J. W., Streit, F., Sullivan, P. F., Tiemeier, H., Uher, R., der Auwera, S. V., Weissman, M. M., O'Reilly, P. F. & Lewis, C. M., 1 Mar 2020, In: Biological psychiatry. 87, 5, p. 419-430 12 p.

    Research output: Contribution to journalArticlepeer-review

  11. Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

    UK10K Consortium & Breen, G., 21 Jan 2020, In: Nature Communications. 10, 1, 357.

    Research output: Contribution to journalArticlepeer-review

  12. 2019
  13. Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches

    Eating Disorders Working Group of the Psychiatric Genomics Consortium, 15 Oct 2019, In: Biological psychiatry. 86, 8, p. 577-586 10 p.

    Research output: Contribution to journalArticlepeer-review

  14. Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

    Anorexia Nervosa Genetics Initiative, Watson, H. J., Yilmaz, Z., Thornton, L. M., Hübel, C., Coleman, J. R. I., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Medland, S. E., Ripke, S., Yao, S., Giusti-Rodríguez, P., Hanscombe, K. B., Purves, K. L., Adan, R. A. H., Alfredsson, L., Ando, T. & 31 others, Andreassen, O. A., Baker, J. H., Berrettini, W. H., Boehm, I., Boni, C., Perica, V. B., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Crowley, J. J., Danner, U. N., Davis, O. S. P., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J. E., Dick, D. M., Dikeos, D., Farmer, A., Helder, S. G., Kalsi, G., McGuffin, P., Roberts, M., Schmidt, U., Treasure, J. & Breen, G., 31 Aug 2019, In: Nature Genetics. 51, 8, p. 1207–1214 8 p.

    Research output: Contribution to journalArticlepeer-review

  15. Trajectories of suicidal ideation during 12 weeks of escitalopram or nortriptyline antidepressant treatment among 811 patients with major depressive disorder

    Madsen, T., Buttenschøn, H. N., Uher, R., Behrendt-Møller, I., Perroud, N., Maier, W., Hauser, J., Dernovsek, M. Z., Henigsberg, N., Souery, D., Rietschel, M., McGuffin, P., Aitchison, K. J., Mors, O. & Köhler-Forsberg, O., 16 Jul 2019, In: Journal of Clinical Psychiatry. 80, 4, 18m12575.

    Research output: Contribution to journalArticlepeer-review

  16. Genome-wide burden of rare short deletions is enriched in Major Depressive Disorder in four cohorts

    Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 others, Mors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 15 Jun 2019, In: Biological psychiatry. 85, 12, p. 1065-1073 9 p.

    Research output: Contribution to journalArticlepeer-review

  17. Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 11 Jun 2019, In: Nature Communications. 10, 1, p. 1-18 18 p., 2548.

    Research output: Contribution to journalArticlepeer-review

  18. Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia

    Deciphering Developmental Disorders Study, UK10K Consortium, NIHR BioResource, Simpson, M. A., Prigmore, E., Jones, P., Armstrong, R., Bennett, C., Berg, J., Bernhard, B., Cooper, N., Cox, H., Flinter, F., Fry, A., Gill, H., Gray, E., Harrison, V., Irving, M., Josifova, D., Langman, C. & 44 others, Mohammed, S., Moore, D., Murphy, H., Roberts, J., Tischkowitz, M., Wright, M., Bolton, P., Breen, G., Clement, G., Collier, D., Curran, S., Ellis, P., Evans, D., Hart, D., Hubbard, T., Hysi, P., Jamshidi, Y., Lachance, G., Lopes, M., McGuffin, P., Metrustry, S., Moayyeri, A., Onoufriadis, A., Parr, J. R., Quaye, L., Sharp, S. I., Small, K., Spasic-Boskovic, O., Stevens, E., Valdes, A., Walters, J. T. R., Wang, Y., Bennett, D., Bradley, J. R., Davis, J., Koziell, A., Machado, R., Richards, M., Smith, K., Southgate, L., Thomas, E., Trembath, R., Williamson, C. & Yong, P., 2 May 2019, In: American Journal of Human Genetics. 104, 5, p. 948-956 9 p.

    Research output: Contribution to journalArticlepeer-review

  19. Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

    eQTLGen Consortium, Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M. W., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L. & 31 others, Agerbo, E., Akil, H., Albani, D., Alliey-Rodriguez, N., Als, T. D., Anjorin, A., Antilla, V., Awasthi, S., Badner, J. A., Bækvad-Hansen, M., Barchas, J. D., Bass, N., Bauer, M., Belliveau, R., Bergen, S. E., Pedersen, C. B., Bøen, E., Boks, M. P., Boocock, J., Budde, M., Bunney, W., Burmeister, M., Bybjerg-Grauholm, J., Byerley, W., Casas, M., de Jong, S., Kandaswamy, R., McGuffin, P., Mullins, N., Young, A. H. & Lewis, C. M., May 2019, In: Nature Genetics. 51, 5, p. 793-803 11 p.

    Research output: Contribution to journalArticlepeer-review

  20. Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2019, In: JAMA Psychiatry. 76, 4, p. 399-408 10 p.

    Research output: Contribution to journalArticlepeer-review

  21. Identification of common genetic risk variants for autism spectrum disorder

    Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, 25 Feb 2019, In: Nature Genetics. 51, 3, p. 431-444 14 p.

    Research output: Contribution to journalArticlepeer-review

  22. Family functioning, trauma exposure and PTSD: A cross sectional study

    Dorrington, S., Zavos, H., Ball, H., McGuffin, P., Sumathipala, A., Siribaddana, S., Rijsdijk, F., Hatch, S. L. & Hotopf, M., 15 Feb 2019, In: Journal of Affective Disorders. 245, p. 645-652 8 p.

    Research output: Contribution to journalArticlepeer-review

  23. Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

    Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2019, In: Molecular Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  24. Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder

    Köhler-Forsberg, O., Larsen, E. R., Buttenschon, H. N., Rietschel, M., Hauser, J., Souery, D., Maier, W., Farmer, A., McGuffin, P., Aitchison, K. J., Uher, R. & Mors, O., 2019, In: British Journal of Psychiatry. 215, 2, p. 494-501 8 p.

    Research output: Contribution to journalArticlepeer-review

  25. 2018
  26. Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

    Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Eley, T. C., Gaspar, H. A., McGuffin, P., Mullins, N., O'Reilly, P. F., Lewis, C. M. & Breen, G., 20 Dec 2018, In: PLoS ONE. 13, 12, e0209160.

    Research output: Contribution to journalArticlepeer-review

  27. Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

    Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 1 Dec 2018, In: Communications Biology. 1, 1, 163.

    Research output: Contribution to journalArticlepeer-review

  28. Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)

    Ren, H., Fabbri, C., Uher, R., Rietschel, M., Mors, O., Henigsberg, N., Hauser, J., Zobel, A., Maier, W., Dernovsek, M. Z., Souery, D., Cattaneo, A., Breen, G., Craig, I. W., Farmer, A. E., McGuffin, P., Lewis, C. M. & Aitchison, K. J., 1 Dec 2018, In: Translational psychiatry. 8, 1, 150.

    Research output: Contribution to journalArticlepeer-review

  29. Unravelling the GSK3β-related genotypic interaction network influencing hippocampal volume in recurrent major depressive disorder

    Inkster, B., Simmons, A., Cole, J. H., Schoof, E., Linding, R., Nichols, T., Muglia, P., Holsboer, F., Sämann, P. G., McGuffin, P., Fu, C. H. Y., Miskowiak, K., Matthews, P. M., Zai, G. & Nicodemus, K., 1 Oct 2018, In: Psychiatric Genetics. 28, 5, p. 77-84 8 p.

    Research output: Contribution to journalArticlepeer-review

  30. Genetic disposition to inflammation and response to antidepressants in major depressive disorder

    Zwicker, A., Fabbri, C., Rietschel, M., Hauser, J., Mors, O., Maier, W., Zobel, A., Farmer, A., Aitchison, K. J., McGuffin, P., Lewis, C. M. & Uher, R., 7 Aug 2018, In: Journal of psychiatric research.

    Research output: Contribution to journalArticlepeer-review

  31. Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

    Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 others, Aitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., 28 Jun 2018, In: European Neuropsychopharmacology.

    Research output: Contribution to journalArticlepeer-review

  32. New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C., Tansey, K., Perlis, R., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 others, Biernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R. & Lewis, C., 22 May 2018, In: The pharmacogenomics journal. 18, p. 413-421

    Research output: Contribution to journalArticlepeer-review

  33. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J. & 32 others, Cai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F., 1 May 2018, In: Nature Genetics. 50, 5, p. 668-681

    Research output: Contribution to journalArticlepeer-review

  34. Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables

    Iniesta, R., Hodgson, K., Stahl, D. R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovšek, M. Z., Souery, D., Dobson, R., Aitchison, K. J., Farmer, A., McGuffin, P., Lewis, C. M. & Uher, R., 3 Apr 2018, In: Scientific Reports. 8, 1, 9 p., 5530 .

    Research output: Contribution to journalArticlepeer-review

  35. 2017
  36. New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 others, Biernacka, J. M., Weinshilboum, R. M., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Uher, R. & Lewis, C. M., 21 Nov 2017, In: The pharmacogenomics journal.

    Research output: Contribution to journalArticlepeer-review

  37. One year double blind study of high vs low frequency subcallosal cingulate stimulation for depression

    Eitan, R., Fontaine, D., Benoît, M., Giordana, C., Darmon, N., Israel, Z., Linesky, E., Arkadir, D., Ben-Naim, S., Iserlles, M., Bergman, H., Hulse, N., Abdelghani, M., McGuffin, P., Farmer, A., DeLea, P., Ashkan, K. & Lerer, B., 3 Oct 2017, In: Journal of psychiatric research.

    Research output: Contribution to journalArticlepeer-review

  38. Advancing psychiatric genetics through dissecting heterogeneity

    Hodgson, K., McGuffin, P. & Lewis, C. M., 1 Oct 2017, In: Human Molecular Genetics. 26, R2, p. R160-R165

    Research output: Contribution to journalReview articlepeer-review

  39. Genetic and other risk factors for suicidal ideation and the relationship with depression

    Dutta, R., Ball, H. A., Siribaddana, S., Sumathipala, A., Samaraweera, S., McGuffin, P. & Hotopf, M., 13 Sep 2017, In: Psychological Medicine. 47, 14, p. 2438-2449 12 p.

    Research output: Contribution to journalArticlepeer-review

  40. Childhood maltreatment and the medical morbidity in bipolar disorder: a case-control study

    Hosang, G. M., Fisher, H. L., Uher, R., Cohen-Woods, S., Maughan, B., McGuffin, P. & Farmer, A. E., 7 Sep 2017, In: International Journal of Bipolar Disorders. 5, 1, p. 30

    Research output: Contribution to journalArticlepeer-review

  41. Interaction between childhood maltreatment on immunogenetic risk in depression: discovery and replication in clinical case-control samples

    Cohen-Woods, S., Fisher, H. L., Ahmetspahic, D., Douroudis, K., Stacey, D., Hosang, G. M., Korszun, A., Owen, M., Craddock, N., Arolt, V., Dannowski, U., Breen, G., Craig, I. W., Farmer, A., Baune, B. T., Lewis, C. M., Uher, R. & McGuffin, P., 1 Sep 2017, In: Brain, Behavior, and Immunity. 67, p. 203-210

    Research output: Contribution to journalArticlepeer-review

  42. Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa

    Duncan, L., Yilmaz, Z., Gaspar, H., Walters, R., Goldstein, J., Anttila, V., Bulik-Sullivan, B., Ripke, S., Thornton, L., Hinney, A., Daly, M., Sullivan, P. F., Zeggini, E., Breen, G., Bulik, C. M., Duncan, L., Yilmaz, Z., Gaspar, H., Walters, R., Goldstein, J. & 216 others, Anttila, V., Bulik-Sullivan, B., Ripke, S., Adan, R., Alfredsson, L., Ando, T., Andreassen, O., Aschauer, H., Baker, J., Barrett, J., Bencko, V., Bergen, A., Berrettini, W., Birgegård, A., Boni, C., Perica, V. B., Brandt, H., Burghardt, R., Carlberg, L., Cassina, M., Cesta, C., Cichon, S., Clementi, M., Cohen-Woods, S., Coleman, J., Cone, R., Courtet, P., Crawford, S., Crow, S., Crowley, J., Danner, U., Davis, O., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J., Danielle, D. N., Dikeos, D., Dina, C., Ding, B., Dmitrzak-Weglarz, M., Docampo, E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Espeseth, T., Estivill, X., Favaro, A., Fernández-Aranda, F., Fichter, M., Finan, C., Fischer, K., Floyd, J., Föcker, M., Foretova, L., Forzan, M., Fox, C., Franklin, C., Gaborieau, V., Gallinger, S., Gambaro, G., Giegling, I., Gonidakis, F., Gorwood, P., Gratacos, M., Guillaume, S., Guo, Y., Hakonarson, H., Halmi, K., Harrison, R., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S., Hendriks, J., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Hilliard, C., Huckins, L., Hudson, J., Huemer, J., Imgart, H., Inoko, H., Jall, S., Jamain, S., Janout, V., Jiménez-Murcia, S., Johnson, C., Jordan, J., Julià, A., Juréus, A., Kalsi, G., Kaplan, A., Kaprio, J., Karhunen, L., Karwautz, A., Kas, M., Kaye, W., Kennedy, M., Kennedy, J., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y. R., Klareskog, L., Klump, K., Knudsen, G. P., Koeleman, B., Koubek, D., La Via, M., Landén, M., Le Hellard, S., Leboyer, M., Levitan, R., Li, D., Lichtenstein, P., Lilenfeld, L., Lissowska, J., Lundervold, A., Magistretti, P., Maj, M., Mannik, K., Marsal, S., Kaminska, D., Martin, N., Mattingsdal, M., McDevitt, S., McGuffin, P., Merl, E., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, J., Mitchell, K., Monteleone, P., Monteleone, A. M., Montgomery, G., Mortensen, P., Munn-Chernoff, M., Müller, T., Nacmias, B., Navratilova, M., Nilsson, I., Norring, C., Ntalla, I., Ophoff, R., O’Toole, J., Palotie, A., Pantel, J., Papezova, H., Parker, R., Pinto, D., Rabionet, R., Raevuori, A., Rajewski, A., Ramoz, N., William Rayner, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S., Schmidt, U., Schork, N., Schosser, A., Scott, L., Seitz, J., Slachtova, L., Sladek, R., Eline Slagboom, P., Slof-Op ’t Landt, M., Slopien, A., Smith, T., Soranzo, N., Sorbi, S., Southam, L., Steen, V., Strengman, E., Strober, M., Szatkiewicz, J., Szeszenia-Dabrowska, N., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tschöp, M., Tsitsika, A., Tziouvas, K., van Elburg, A., van Furth, E., Wade, T., Wagner, G., Walton, E., Watson, H., Wichmann, H. E., Widen, E., Woodside, B., Yanovski, J., Yao, S., Zerwas, S., Zipfel, S., Thornton, L., Hinney, A., Daly, M., Sullivan, P. F., Zeggini, E., Breen, G. & Bulik, C. M., 1 Sep 2017, In: American Journal of Psychiatry. 174, 9, p. 850-858 9 p.

    Research output: Contribution to journalArticlepeer-review

  43. Interaction between the FTOgene, body mass index and depression: meta-analysis of 13701 individuals

    Rivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., Milaneschi, Y., Kloiber, S., Cohen-Woods, S., Rucker, J., Aitchison, K. J., Bergmann, S., Boomsma, D. I., Craddock, N., Gill, M., Holsboer, F., Hottenga, J-J., Korszun, A., Kutalik, Z., Lucae, S. & 18 others, Maier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P., 1 Aug 2017, In: British Journal of Psychiatry. 211, 2, p. 70-76 7 p.

    Research output: Contribution to journalArticlepeer-review

  44. Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals

    Rivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., Milaneschi, Y., Kloiber, S., Cohen-Woods, S., Rucker, J., Aitchison, K. J., Bergmann, S., Boomsma, D. I., Craddock, N., Gill, M., Holsboer, F., Hottenga, J-J., Korszun, A., Kutalik, Z., Lucae, S. & 18 others, Maier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P., 22 Jun 2017, In: The British journal of psychiatry : the journal of mental science.

    Research output: Contribution to journalArticlepeer-review

  45. Pharmacogenetics of antidepressant response: A polygenic approach

    Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium, 3 Apr 2017, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 75, 0, p. 128-134 7 p.

    Research output: Contribution to journalArticlepeer-review

  46. Genetic effects influencing risk for major depressive disorder in China and Europe

    Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S-A., Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschøn, H. N., Byrne, E. M., Cichon, S., Clarke, T-K., Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F. & 77 others, Dunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P., Hardiman, O., Hayward, C., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Hottenga, J-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J. A., Lang, M., Li, Q. S., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Martin, N. G., McGrath, P. J., McGuffin, P., McIntosh, A. M., Medland, S. E., Mehta, D., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D. R., Nöthen, M. M., Owen, M. J., Penninx, B. W. J. H., Pergadia, M. L., Perlis, R. H., Peyrot, W. J., Porteous, D. J., Potash, J. B., Rice, J. P., Rietschel, M., Riley, B. P., Rivera, M., Schoevers, R., Schulze, T. G., Shi, J., Shyn, S. I., Smit, J. H., Smoller, J. W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., Van der Auwera, S., van Grootheest, G., van Hemert, A. M., Völzke, H., Webb, B. T., Weissman, M. M., Wellmann, J., Willemsen, G., Witt, S. H., Levinson, D. F., Lewis, C. M., Wray, N. R., Flint, J., Sullivan, P. F. & Kendler, K. S., 28 Mar 2017, In: Translational psychiatry. 7, 3, p. e1074

    Research output: Contribution to journalArticlepeer-review

  47. The DAOA gene is associated with schizophrenia in the Taiwanese population

    Chu, C-S., Chik-keung Chow, P., Cohen-Woods, S., Gaysina, D., Tang, K-Y. & McGuffin, P., 7 Mar 2017, In: Psychiatry Research.

    Research output: Contribution to journalArticlepeer-review

  48. Gottesman, the Enemy of Genetic Determinism and His Role in a Curious Legal Case

    McGuffin, P., 1 Mar 2017, In: Clinical Psychological Science. 5, 2, p. 427-428 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  49. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

    Hinney, A., Kesselmeier, M., Jall, S., Volckmar, A. L., Föcker, M., Antel, J., Heid, I. M., Winkler, T. W., Grant, S. F. A., Guo, Y., Bergen, A. W., Kaye, W., Berrettini, W., Hakonarson, H., Herpertz-Dahlmann, B., De Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Egberts, K. M. & 529 others, Adan, R., Brandys, M., Van Elburg, A., Boraska Perica, V., Müller, T. D., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., Perica, V. B., Franklin, C. S., Floyd, J. A. B., Thornton, L. M., Huckins, L. M., Southam, L., Rayner, N. W., Tachmazidou, I., Klump, K. L., Treasure, J., Lewis, C. M., Schmidt, U., Tozzi, F., Iezebrink, K., Hebebrand, J., Gorwood, P., Adan, R. A. H., Kas, M. J. H., Favaro, A., Santonastaso, P., Fernández-Aranda, F., Gratacos, M., Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori-Helkamaa, A., Van Furth, E. F., Slof-Op’t Landt, M. C. T., Hudson, J. I., Reichborn-Kjennerud, T., Knudsen, G. P. S., Monteleone, P., Kaplan, A. S., Karwautz, A., Hakonarson, H., Berrettini, W. H., Guo, Y., Li, D., Schork, N. J., Komaki, G., Ando, T., Inoko, H., Esko, T., Fischer, K., Männik, K., Metspalu, A., Baker, J. H., Cone, R. D., Dackor, J., DeSocio, J. E., Hilliard, C. E., O’Toole, J. K., Pantel, J., Szatkiewicz, J. P., Taico, C., Zerwas, S., Trace, S. E., Davis, O. S. P., Helder, S., Bühren, K., Burghardt, R., de Zwaan, M., Egberts, K., Ehrlich, S., Herpertz-Dahlmann, B., Herzog, W., Imgart, H., Scherag, A., Scherag, S., Zipfel, S., Boni, C., Ramoz, N., Versini, A., Brandys, M. K., Danner, U. N., de Kove, C., Hendriks, J., Koeleman, B. P. C., Ophoff, R. A., Strengman, E., van Elburg, A. A., Bruson, A., Clementi, M., Degortes, D., Forzan, M., Tenconi, E., Docampo, E., Jiménez-Murcia, G. E. S., Lissowska, J., Rajewski, A., Szeszenia-Dabrowska, N., Slopien, A., Hauser, J., Karhunen, L., Meulenbelt, I., Slagboom, P. E., Tortorella, A., Maj, M., Dedoussis, G., Dikeos, D., Gonidakis, F., Tziouvas, K., Tsitsika, A., Papezova, H., Slachtova, L., Martaskova, D., Kennedy, J. L., Levitan, R. D., Yilmaz, Z., Huemer, J., Koubek, D., Merl, E., Wagner, G., Lichtenstein, P., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Cichon, S., Giegling, I., Herms, S., Rujescu, D., Schreiber, S., Wichmann, H. E., Christian, D., Sladek, R., Gambaro, G., Soranzo, N., Julia, A., Marsal, S., Rabionet, R., Gaborieau, V., Dick, D. M., Palotie, A., Ripatti, S., Widén, E., Andreassen, O. A., Espeseth, T., Lundervold, A., Reinvang, I., Steen, V. M., Le Hellard, S., Mattingsdal, M., Ntalla, I., Bencko, V., Foretova, L., Janout, V., Navratilova, M., Gallinger, S., Pinto, D., Scherer, S. W., Aschauer, H., Carlberg, L., Schosser, A., Alfredsson, L., Ding, B., Klareskog, L., Padyukov, L., Finan, C., Kalsi, G., Roberts, M., Logan, D. W., Peltonen, L., Ritchie, G. R. S., Barrett, J. C., Estivill, X., Hinney, A., Sullivan, P. F., Collier, D. A., Zeggini, E., Bulik, C. M., Anderson, C. A., Barrett, J. C., Floyd, J. A. B., Franklin, C. S., McGinnis, R., Soranzo, N., Zeggini, E., Sambrook, J., Stephens, J., Ouwehand, W. H., McArdle, W. L., Ring, S. M., Strachan, D. P., Alexander, G., Bulik, C. M., Collier, D. A., Conlon, P. J., Dominiczak, A., Duncanson, A., Hill, A., Langford, C., Lord, G., Maxwell, A. P., Morgan, L., Peltonen, L., Sandford, R. N., Sheerin, N., Vannberg, F. O., Blackburn, H., Chen, W. M., Edkins, S., Gillman, M., Gray, E., Hunt, S. E., Nengut, S. G., Potter, S., Rich, S. S., Simpkin, D., Whittaker, P., Adair, L. S., Ang, W., Atalay, M., van Beijsterveldt, T., Bergen, N., Benke, K., Berry, D. J., Boomsma, D. I., Bradfield, J. P., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Das, S., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Evans, D. M., Feenstra, B., Flexeder, C., Frayling, T., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M., Grant, S. F., Groen-Blokhuis, M., Goh, L. K., Guxens, M., Hakonarson, H., Hattersley, A. T., Haworth, C. M., Hadley, D., Hebebrand, J., Heinrich, J., Hinney, A., Hirschhorn, J. N., Hocher, B., Holloway, J. W., Holst, C., Hottenga, J. J., Horikoshi, M., Huikari, V., Hypponen, E., Iñiguez, C., Jaddoe, V. W., Jarvelin, M. R., Kaakinen, M., Kilpeläinen, T. O., Kirin, M., Kowgier, M., Lakka, H. M., Lakka, T. A., Lange, L. A., Lawlor, D. A., Lehtimäki, T., Lewin, A., Lindgren, C., Lindi, V., Maggi, R., Marsh, J., McCarthy, M. I., Melbye, M., Middeldorp, C., Millwood, I., Mohlke, K. L., Mook-Kanamori, D. O., Murray, J. C., Nivard, M., Nohr, E. A., Ntalla, I., Oken, E., Ong, K. K., O'Reilly, P. F., Palmer, L. J., Panoutsopoulou, K., Pararajasingham, J., Pearson, E. R., Pennell, C. E., Power, C., Price, T. S., Prokopenko, I., Raitakari, O. T., Rodriguez, A., Salem, R. M., Saw, S. M., Scherag, A., Sebert, S., Siitonen, N., Simell, O., Sørensen, T. I., Sovio, U., Pourcain, B. S., Strachan, D. P., Sunyer, J., Taal, H. R., Teo, Y. Y., Thiering, E., Tiesler, C., Timpson, N. J., Uitterlinden, A. G., Valcárcel, B., Warrington, N. M., White, S., Widén, E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zeggini, E., Elks, C. E., Perry, J. R., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Byrne, E. M., Cousminer, D. L., Gudbjartsson, D. F., Esko, T., Feenstra, B., Hottenga, J. J., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S. H., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K., Smith, E. N., Ulivi, S., Warrington, M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Coviello, A. D., d'Adamo, P., de Faire, U., de Geus, E. J., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Eriksson, J., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Geller, F., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hofman, A., Hu, F. B., Illig, T., Järvelin, M. R., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kilpeläinen, T. O., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., Martin, N. G., McArdle, W. L., Melbye, M., Mooser, V., Murray, J. C., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Palmer, L. J., Palotie, A., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Pouta, A., Porcu, E., Rafnar, T., Rice, J. P., Ring, S. M., Rivadeneira, F., Rudan, I., Sala, C., Salomaa, V., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V., Shuldiner, A. R., Soranzo, N., Sovio, U., Srinivasan, S. R., Strachan, D. P., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., van Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D. M., Weedon, M. N., Wichmann, H. E., Willemsen, G., Wilson, J. F., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Montgomery, G. W., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Uitterlinden, A. G., Widen, E., Murabito, J. M., Ong, K. K., Murray, A., Brandt, H., Crawford, S., Crow, S., Fichter, M. M., Halmi, K. A., Johnson, C., Kaplan, A. S., La Via, M., Mitchell, J., Strober, M., Rotondo, A., Treasure, J., Woodside, D. B., Bulik, C. M., Keel, P., Klump, K. L., Lilenfeld, L., Thornton, L. M., Plotnicov, K., Bergen, A. W., Berrettini, W., Kaye, W. & Magistretti, P., 1 Feb 2017, In: Molecular Psychiatry. 22, 2, p. 192-201 10 p.

    Research output: Contribution to journalArticlepeer-review

  50. 2016
  51. Stressful life events and Catechol-O-methyl-transferase (COMT) gene in bipolar disorder

    Hosang, G. M., Fisher, H., Cohen-Woods, S., McGuffin, P. & Farmer, A. E., 22 Dec 2016, (Accepted/In press) In: Depression and Anxiety.

    Research output: Contribution to journalArticlepeer-review

  52. Machine Learning, Statistical Learning and the Future of Biological Research in Psychiatry

    Iniesta, R., Stahl, D. R. & McGuffin, P., Sep 2016, In: Psychological medicine. 46, 12, p. 2455-2465 11 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  53. Analysis of the effects of depression associated polymorphisms on the activity of the BICC1 promoter in amygdala neurones

    Davidson, S., Shanley, L., Cowie, P., Lear, M., McGuffin, P., Quinn, J. P., Barrett, P. & MacKenzie, A., 1 Aug 2016, In: Pharmacogenomics Journal. 16, 4, p. 366-374 9 p.

    Research output: Contribution to journalArticlepeer-review

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