King's College London

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Research Outputs

  1. 2018
  2. New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C. , Tansey, K. , Perlis, R. , Hauser, J. , Henigsberg, N. , Maier, W. , Mors, O. , Placentino, A. , Rietschel, M. , Souery, D. , Breen, G. , Curtis, C. , Sang-Hyuk, L. , Newhouse, S. , Patel, H. , Guipponi, M. , Perroud, N. , Bondolfi, G. , O'Donovan, M. , Lewis, G. & 8 others Biernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R. & Lewis, C. 22 May 2018 In : The pharmacogenomics journal. 18, p. 413-421

    Research output: Contribution to journalArticle

  3. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R. , Ripke, S. , Mattheisen, M. , Trzaskowski, M. , Byrne, E. M. , Abdellaoui, A. , Adams, M. J. , Agerbo, E. , Air, T. M. , Andlauer, T. M. F. , Bacanu, S. , Bækvad-hansen, M. , Beekman, A. F. T. , Bigdeli, T. B. , Binder, E. B. , Blackwood, D. R. H. , Bryois, J. , Buttenschøn, H. N. , Bybjerg-grauholm, J. & 32 others Cai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-conde, L., Couvy-duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F. 1 May 2018 In : Nature Genetics. 50, 5, p. 668-681

    Research output: Contribution to journalArticle

  4. Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables

    Iniesta, R., Hodgson, K., Stahl, D. R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovšek, M. Z., Souery, D., Dobson, R. M., Aitchison , K. J., Farmer, A. E., McGuffin, P., Lewis, C. M. & Uher, R. 3 Apr 2018 In : Scientific Reports.

    Research output: Contribution to journalArticle

  5. 2017
  6. New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C. , Tansey, K. E. , Perlis, R. H. , Hauser, J. , Henigsberg, N. , Maier, W. , Mors, O. , Placentino, A. , Rietschel, M. , Souery, D. , Breen, G. , Curtis, C. , Sang-Hyuk, L. , Newhouse, S. , Patel, H. , Guipponi, M. , Perroud, N. , Bondolfi, G. , O'Donovan, M. , Lewis, G. & 8 others Biernacka, J. M., Weinshilboum, R. M., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Uher, R. & Lewis, C. M. 21 Nov 2017 In : The pharmacogenomics journal.

    Research output: Contribution to journalArticle

  7. One year double blind study of high vs low frequency subcallosal cingulate stimulation for depression

    Eitan, R., Fontaine, D., Benoît, M., Giordana, C., Darmon, N., Israel, Z., Linesky, E., Arkadir, D., Ben-Naim, S., Iserlles, M., Bergman, H., Hulse, N., Abdelghani, M., McGuffin, P., Farmer, A., DeLea, P., Ashkan, K. & Lerer, B. 3 Oct 2017 In : Journal of psychiatric research.

    Research output: Contribution to journalArticle

  8. Advancing psychiatric genetics through dissecting heterogeneity

    Hodgson, K., McGuffin, P. & Lewis, C. M. 1 Oct 2017 In : Human Molecular Genetics. 26, R2, p. R160-R165

    Research output: Contribution to journalReview article

  9. Childhood maltreatment and the medical morbidity in bipolar disorder: a case-control study

    Hosang, G. M., Fisher, H. L., Uher, R., Cohen-Woods, S., Maughan, B., McGuffin, P. & Farmer, A. E. 7 Sep 2017 In : International Journal of Bipolar Disorders. 5, 1, p. 30

    Research output: Contribution to journalArticle

  10. Interaction between childhood maltreatment on immunogenetic risk in depression: discovery and replication in clinical case-control samples

    Cohen-Woods, S., Fisher, H. L., Ahmetspahic, D., Douroudis, K., Stacey, D., Hosang, G. M., Korszun, A., Owen, M., Craddock, N., Arolt, V., Dannowski, U., Breen, G., Craig, I. W., Farmer, A., Baune, B. T., Lewis, C. M., Uher, R. & McGuffin, P. 1 Sep 2017 In : Brain, behavior, and immunity. 67, p. 203-210

    Research output: Contribution to journalArticle

  11. Interaction between the FTOgene, body mass index and depression: meta-analysis of 13701 individuals

    Rivera, M. , Locke, A. E. , Corre, T. , Czamara, D. , Wolf, C. , Ching-Lopez, A. , Milaneschi, Y. , Kloiber, S. , Cohen-Woods, S. , Rucker, J. , Aitchison, K. J. , Bergmann, S. , Boomsma, D. I. , Craddock, N. , Gill, M. , Holsboer, F. , Hottenga, J-J. , Korszun, A. , Kutalik, Z. , Lucae, S. & 18 others Maier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P. 1 Aug 2017 In : British Journal of Psychiatry. 211, 2, p. 70-76 7 p.

    Research output: Contribution to journalArticle

  12. Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals

    Rivera, M. , Locke, A. E. , Corre, T. , Czamara, D. , Wolf, C. , Ching-Lopez, A. , Milaneschi, Y. , Kloiber, S. , Cohen-Woods, S. , Rucker, J. , Aitchison, K. J. , Bergmann, S. , Boomsma, D. I. , Craddock, N. , Gill, M. , Holsboer, F. , Hottenga, J-J. , Korszun, A. , Kutalik, Z. , Lucae, S. & 18 others Maier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P. 22 Jun 2017 In : The British journal of psychiatry : the journal of mental science.

    Research output: Contribution to journalArticle

  13. Genetic and other risk factors for suicidal ideation and the relationship with depression

    Dutta, R., Ball, H. A., Siribaddana, S., Sumathipala, A., Samaraweera, S., McGuffin, P. & Hotopf, M. H. 8 May 2017 In : Psychological medicine. p. 1-12 12 p.

    Research output: Contribution to journalArticle

  14. Pharmacogenetics of antidepressant response: A polygenic approach

    Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium 3 Apr 2017 In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 75, p. 128-134 7 p.

    Research output: Contribution to journalArticle

  15. Genetic effects influencing risk for major depressive disorder in China and Europe

    Bigdeli, T. B. , Ripke, S. , Peterson, R. E. , Trzaskowski, M. , Bacanu, S-A. , Abdellaoui, A. , Andlauer, T. F. M. , Beekman, A. T. F. , Berger, K. , Blackwood, D. H. R. , Boomsma, D. I. , Breen, G. , Buttenschøn, H. N. , Byrne, E. M. , Cichon, S. , Clarke, T-K. , Couvy-Duchesne, B. , Craddock, N. , de Geus, E. J. C. , Degenhardt, F. & 77 others Dunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P., Hardiman, O., Hayward, C., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Hottenga, J-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J. A., Lang, M., Li, Q. S., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Martin, N. G., McGrath, P. J., McGuffin, P., McIntosh, A. M., Medland, S. E., Mehta, D., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D. R., Nöthen, M. M., Owen, M. J., Penninx, B. W. J. H., Pergadia, M. L., Perlis, R. H., Peyrot, W. J., Porteous, D. J., Potash, J. B., Rice, J. P., Rietschel, M., Riley, B. P., Rivera, M., Schoevers, R., Schulze, T. G., Shi, J., Shyn, S. I., Smit, J. H., Smoller, J. W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., Van der Auwera, S., van Grootheest, G., van Hemert, A. M., Völzke, H., Webb, B. T., Weissman, M. M., Wellmann, J., Willemsen, G., Witt, S. H., Levinson, D. F., Lewis, C. M., Wray, N. R., Flint, J., Sullivan, P. F. & Kendler, K. S. 28 Mar 2017 In : Translational psychiatry. 7, 3, p. e1074

    Research output: Contribution to journalArticle

  16. The DAOA gene is associated with schizophrenia in the Taiwanese population

    Chu, C-S., Chik-keung Chow, P., Cohen-Woods, S., Gaysina, D., Tang, K-Y. & McGuffin, P. 7 Mar 2017 In : Psychiatry Research.

    Research output: Contribution to journalArticle

  17. Gottesman, the Enemy of Genetic Determinism and His Role in a Curious Legal Case

    McGuffin, P. 1 Mar 2017 In : Clinical Psychological Science. 5, 2, p. 427-428 2 p.

    Research output: Contribution to journalComment/debate

  18. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

    Hinney, A. , Kesselmeier, M. , Jall, S. , Volckmar, A. L. , Föcker, M. , Antel, J. , Heid, I. M. , Winkler, T. W. , Grant, S. F. A. , Guo, Y. , Bergen, A. W. , Kaye, W. , Berrettini, W. , Hakonarson, H. , Herpertz-Dahlmann, B. , De Zwaan, M. , Herzog, W. , Ehrlich, S. , Zipfel, S. , Egberts, K. M. & 529 others Adan, R., Brandys, M., Van Elburg, A., Boraska Perica, V., Müller, T. D., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., Perica, V. B., Franklin, C. S., Floyd, J. A. B., Thornton, L. M., Huckins, L. M., Southam, L., Rayner, N. W., Tachmazidou, I., Klump, K. L., Treasure, J., Lewis, C. M., Schmidt, U., Tozzi, F., Iezebrink, K., Hebebrand, J., Gorwood, P., Adan, R. A. H., Kas, M. J. H., Favaro, A., Santonastaso, P., Fernández-Aranda, F., Gratacos, M., Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori-Helkamaa, A., Van Furth, E. F., Slof-Op’t Landt, M. C. T., Hudson, J. I., Reichborn-Kjennerud, T., Knudsen, G. P. S., Monteleone, P., Kaplan, A. S., Karwautz, A., Hakonarson, H., Berrettini, W. H., Guo, Y., Li, D., Schork, N. J., Komaki, G., Ando, T., Inoko, H., Esko, T., Fischer, K., Männik, K., Metspalu, A., Baker, J. H., Cone, R. D., Dackor, J., DeSocio, J. E., Hilliard, C. E., O’Toole, J. K., Pantel, J., Szatkiewicz, J. P., Taico, C., Zerwas, S., Trace, S. E., Davis, O. S. P., Helder, S., Bühren, K., Burghardt, R., de Zwaan, M., Egberts, K., Ehrlich, S., Herpertz-Dahlmann, B., Herzog, W., Imgart, H., Scherag, A., Scherag, S., Zipfel, S., Boni, C., Ramoz, N., Versini, A., Brandys, M. K., Danner, U. N., de Kove, C., Hendriks, J., Koeleman, B. P. C., Ophoff, R. A., Strengman, E., van Elburg, A. A., Bruson, A., Clementi, M., Degortes, D., Forzan, M., Tenconi, E., Docampo, E., Jiménez-Murcia, G. E. S., Lissowska, J., Rajewski, A., Szeszenia-Dabrowska, N., Slopien, A., Hauser, J., Karhunen, L., Meulenbelt, I., Slagboom, P. E., Tortorella, A., Maj, M., Dedoussis, G., Dikeos, D., Gonidakis, F., Tziouvas, K., Tsitsika, A., Papezova, H., Slachtova, L., Martaskova, D., Kennedy, J. L., Levitan, R. D., Yilmaz, Z., Huemer, J., Koubek, D., Merl, E., Wagner, G., Lichtenstein, P., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Cichon, S., Giegling, I., Herms, S., Rujescu, D., Schreiber, S., Wichmann, H. E., Christian, D., Sladek, R., Gambaro, G., Soranzo, N., Julia, A., Marsal, S., Rabionet, R., Gaborieau, V., Dick, D. M., Palotie, A., Ripatti, S., Widén, E., Andreassen, O. A., Espeseth, T., Lundervold, A., Reinvang, I., Steen, V. M., Le Hellard, S., Mattingsdal, M., Ntalla, I., Bencko, V., Foretova, L., Janout, V., Navratilova, M., Gallinger, S., Pinto, D., Scherer, S. W., Aschauer, H., Carlberg, L., Schosser, A., Alfredsson, L., Ding, B., Klareskog, L., Padyukov, L., Finan, C., Kalsi, G., Roberts, M., Logan, D. W., Peltonen, L., Ritchie, G. R. S., Barrett, J. C., Estivill, X., Hinney, A., Sullivan, P. F., Collier, D. A., Zeggini, E., Bulik, C. M., Anderson, C. A., Barrett, J. C., Floyd, J. A. B., Franklin, C. S., McGinnis, R., Soranzo, N., Zeggini, E., Sambrook, J., Stephens, J., Ouwehand, W. H., McArdle, W. L., Ring, S. M., Strachan, D. P., Alexander, G., Bulik, C. M., Collier, D. A., Conlon, P. J., Dominiczak, A., Duncanson, A., Hill, A., Langford, C., Lord, G., Maxwell, A. P., Morgan, L., Peltonen, L., Sandford, R. N., Sheerin, N., Vannberg, F. O., Blackburn, H., Chen, W. M., Edkins, S., Gillman, M., Gray, E., Hunt, S. E., Nengut, S. G., Potter, S., Rich, S. S., Simpkin, D., Whittaker, P., Adair, L. S., Ang, W., Atalay, M., van Beijsterveldt, T., Bergen, N., Benke, K., Berry, D. J., Boomsma, D. I., Bradfield, J. P., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Das, S., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Evans, D. M., Feenstra, B., Flexeder, C., Frayling, T., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M., Grant, S. F., Groen-Blokhuis, M., Goh, L. K., Guxens, M., Hakonarson, H., Hattersley, A. T., Haworth, C. M., Hadley, D., Hebebrand, J., Heinrich, J., Hinney, A., Hirschhorn, J. N., Hocher, B., Holloway, J. W., Holst, C., Hottenga, J. J., Horikoshi, M., Huikari, V., Hypponen, E., Iñiguez, C., Jaddoe, V. W., Jarvelin, M. R., Kaakinen, M., Kilpeläinen, T. O., Kirin, M., Kowgier, M., Lakka, H. M., Lakka, T. A., Lange, L. A., Lawlor, D. A., Lehtimäki, T., Lewin, A., Lindgren, C., Lindi, V., Maggi, R., Marsh, J., McCarthy, M. I., Melbye, M., Middeldorp, C., Millwood, I., Mohlke, K. L., Mook-Kanamori, D. O., Murray, J. C., Nivard, M., Nohr, E. A., Ntalla, I., Oken, E., Ong, K. K., O'Reilly, P. F., Palmer, L. J., Panoutsopoulou, K., Pararajasingham, J., Pearson, E. R., Pennell, C. E., Power, C., Price, T. S., Prokopenko, I., Raitakari, O. T., Rodriguez, A., Salem, R. M., Saw, S. M., Scherag, A., Sebert, S., Siitonen, N., Simell, O., Sørensen, T. I., Sovio, U., Pourcain, B. S., Strachan, D. P., Sunyer, J., Taal, H. R., Teo, Y. Y., Thiering, E., Tiesler, C., Timpson, N. J., Uitterlinden, A. G., Valcárcel, B., Warrington, N. M., White, S., Widén, E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zeggini, E., Elks, C. E., Perry, J. R., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Byrne, E. M., Cousminer, D. L., Gudbjartsson, D. F., Esko, T., Feenstra, B., Hottenga, J. J., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S. H., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K., Smith, E. N., Ulivi, S., Warrington, M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Coviello, A. D., d'Adamo, P., de Faire, U., de Geus, E. J., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Eriksson, J., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Geller, F., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hofman, A., Hu, F. B., Illig, T., Järvelin, M. R., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kilpeläinen, T. O., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., Martin, N. G., McArdle, W. L., Melbye, M., Mooser, V., Murray, J. C., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Palmer, L. J., Palotie, A., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Pouta, A., Porcu, E., Rafnar, T., Rice, J. P., Ring, S. M., Rivadeneira, F., Rudan, I., Sala, C., Salomaa, V., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V., Shuldiner, A. R., Soranzo, N., Sovio, U., Srinivasan, S. R., Strachan, D. P., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., van Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D. M., Weedon, M. N., Wichmann, H. E., Willemsen, G., Wilson, J. F., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Montgomery, G. W., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Uitterlinden, A. G., Widen, E., Murabito, J. M., Ong, K. K., Murray, A., Brandt, H., Crawford, S., Crow, S., Fichter, M. M., Halmi, K. A., Johnson, C., Kaplan, A. S., La Via, M., Mitchell, J., Strober, M., Rotondo, A., Treasure, J., Woodside, D. B., Bulik, C. M., Keel, P., Klump, K. L., Lilenfeld, L., Thornton, L. M., Plotnicov, K., Bergen, A. W., Berrettini, W., Kaye, W. & Magistretti, P. 1 Feb 2017 In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

    Research output: Contribution to journalArticle

  19. 2016
  20. Machine Learning, Statistical Learning and the Future of Biological Research in Psychiatry

    Iniesta, R., Stahl, D. R. & McGuffin, P. Sep 2016 In : Psychological medicine. 46, 12, p. 2455-2465 11 p.

    Research output: Contribution to journalLiterature review

  21. Evaluation of the validity and utility of a transdiagnostic psychosis dimension encompassing schizophrenia and bipolar disorder

    Reininghaus, U., Böhnke, J. R., Hosang, G., Farmer, A., Burns, T., McGuffin, P. & Bentall, R. P. Aug 2016 In : British Journal of Psychiatry. 209, 2, p. 107-113 7 p.

    Research output: Contribution to journalArticle

  22. Combining clinical variables to optimize prediction of antidepressant treatment outcomes

    Iniesta, R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovsek, M. Z., Souery, D., Stahl, D., Dobson, R., Aitchison, K. J., Farmer, A., Lewis, C. M., McGuffin, P. & Uher, R. Jul 2016 In : Journal of psychiatric research. 78, p. 94-102 9 p.

    Research output: Contribution to journalArticle

  23. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

    Singh, T. , Kurki, M. I. , Curtis, D. , Purcell, S. M. , Crooks, L. , McRae, J. , Suvisaari, J. , Chheda, H. , Blackwood, D. , Breen, G. , Pietilinen, O. , Gerety, S. S. , Ayub, M. , Blyth, M. , Cole, T. , Collier, D. , Coomber, E. L. , Craddock, N. , Daly, M. J. , Danesh, J. & 39 others DiForti, M., Foster, A., Freimer, N. B., Geschwind, D., Johnstone, M., Joss, S., Kirov, G., Körkkö, J., Kuismin, O., Holmans, P., Hultman, C. M., Iyegbe, C., Lönnqvist, J., Mnnikkö, M., McCarroll, S. A., McGuffin, P., McIntosh, A. M., McQuillin, A., Moilanen, J. S., Moore, C., Murray, R. M., Newbury-Ecob, R., Ouwehand, W., Paunio, T., Prigmore, E., Rees, E., Roberts, D., Sambrook, J., Sklar, P., St Clair, D., Veijola, J., Walters, J. T. R., Williams, H., Sullivan, P. F., Hurles, M. E., O'Donovan, M. C., Palotie, A., Owen, M. J. & Barrett, J. C. 29 Mar 2016 In : Nature Neuroscience. 19, 4, p. 571-577 7 p.

    Research output: Contribution to journalArticle

  24. Polygenic interactions with environmental adversity in the aetiology of major depressive disorder

    Mullins, N. , Power, R. A. , Fisher, H. , Hanscombe, K. B. , Euesden, J. , Iniesta, R. , Levinson, D. F. , Weissman, M. M. , Potash, J. B. , Shi, J. , Uher, R. , Cohen-Woods, S. , Rivera, M. , Jones, L. , Jones, I. , Craddock, N. , Owen, M. J. , Korszun, A. , Craig, I. W. , Farmer, A. E. & 3 others McGuffin, P., Breen, G. & Lewis, C. M. Mar 2016 In : Psychological Medicine. 46, 4, p. 759-770 12 p.

    Research output: Contribution to journalArticle

  25. Phenotypic Association Analyses with Copy Number Variation in Recurrent Depressive Disorder

    Rucker, J. J. H. , Tansey, K. E. , Rivera, M. , Pinto, D. , Cohen-Woods, S. , Uher, R. , Aitchison, K. J. , Craddock, N. , Owen, M. J. , Jones, L. , Jones, I. , Korszun, A. , Barnes, M. R. , Preisig, M. , Mors, O. , Maier, W. , Rice, J. , Rietschel, M. , Holsboer, F. , Farmer, A. E. & 4 others Craig, I. W., Scherer, S. W., McGuffin, P. & Breen, G. 15 Feb 2016 In : Biological Psychiatry. 79, 4, p. 329–336

    Research output: Contribution to journalArticle

  26. Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

    Bailey, J. N. C. , Loomis, S. J. , Kang, J. H. , Allingham, R. R. , Gharahkhani, P. , Khor, C. C. , Burdon, K. P. , Aschard, H. , Chasman, D. I. , Igo, R. P. , Hysi, P. G. , Glastonbury, C. A. , Ashley-Koch, A. , Brilliant, M. , Brown, A. A. , Budenz, D. L. , Buil, A. , Cheng, C. Y. , Choi, H. , Christen, W. G. & 60 others Curhan, G., De Vivo, I., Fingert, J. H., Foster, P. J., Fuchs, C., Gaasterland, D., Gaasterland, T., Hewitt, A. W., Hu, F., Hunter, D. J., Khawaja, A. P., Lee, R. K., Li, Z., Lichter, P. R., Mackey, D. A., McGuffin, P., Mitchell, P., Moroi, S. E., Perera, S. A., Pepper, K. W., Qi, Q., Realini, T., Richards, J. E., Ridker, P. M., Rimm, E., Ritch, R., Ritchie, M., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Song, Y. E., Tamimi, R. M., Topouzis, F., Viswanathan, A. C., Verma, S. S., Vollrath, D., Wang, J. J., Weisschuh, N., Wissinger, B., Wollstein, G., Wong, T. Y., Yaspan, B. L., Zack, D. J., Zhang, K., Weinreb, R. N., Pericak-Vance, M. A., Small, K., Hammond, C. J., Aung, T., Liu, Y., Vithana, E. N., MacGregor, S., Craig, J. E., Kraft, P., Howell, G., Hauser, M. A., Pasquale, L. R., Haines, J. L. & Wiggs, J. L. 1 Feb 2016 In : Nature Genetics. 48, 2, p. 189-194 6 p.

    Research output: Contribution to journalArticle

  27. Transcriptomics and the mechanisms of antidepressant efficacy

    Hodgson, K., Tansey, K. E., Powell, T., Coppola, G., Uher, R., Zvezdana Dernovšek, M., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Aitchison, K. J., Craig, I. W., Farmer, A. E., Breen, G., Mcguffin, P. & Dobson, R. 1 Jan 2016 In : European Neuropsychopharmacology. 26, 1, p. 105-112 8 p.

    Research output: Contribution to journalArticle

  28. 2015
  29. Authors' reply

    Fu, C. H. Y., Legge, R. M., Cohen-Woods, S., Cole, J. H., Aitchison, K. J. & McGuffin, P. 1 Oct 2015 In : British Journal of Psychiatry. 207, 4, p. 363-364 2 p.

    Research output: Contribution to journalLetter

  30. Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank

    Wain, L. V. , Shrine, N. , Miller, S. , Jackson, V. E. , Ntalla, I. , Artigas, M. S. , Billington, C. K. , Kheirallah, A. K. , Allen, R. , Cook, J. P. , Probert, K. , Obeidat, M. , Bossé, Y. , Hao, K. , Postma, D. S. , Paré, P. D. , Ramasamy, A. , Mägi, R. , Mihailov, E. , Reinmaa, E. & 138 others Melén, E., O'Connell, J., Frangou, E., Delaneau, O., Freeman, C., Petkova, D., McCarthy, M., Sayers, I., Deloukas, P., Hubbard, R., Pavord, I., Hansell, A. L., Thomson, N. C., Zeggini, E., Morris, A. P., Marchini, J., Strachan, D. P., Tobin, M. D., Hall, I. P., Farrall, M., Barroso, I., Anderson, C. A., Botía, J., Vandrocova, J., Guelfi, S., D'Sa, K., Ryten, M., Trabzuni, D., Matarin, M., Hardy, J. A., Weale, M. E., Varghese, V., Forabosco, P., Farmer, A., McGuffin, P., Zgaga, L., Wilson, J. F., Wild, S. H., Campbell, H., Rudan, I., Smith, C., Walker, R., Liu, J. Z., Tozzi, F., Muglia, P., Waterworth, D. M., Pillai, S. G., Yuan, X., Mooser, V., Middleton, L., Kooner, J., Chambers, J. C., Berrettini, W., Knouff, C. W., Waeber, G., Vollenweider, P., Preisig, M., Wareham, N. J., Zhao, J. H., Loos, R. J. F., Khaw, K. T., Grundy, S., Barter, P., Mahley, R., Kesaniemi, A., McPherson, R., Vincent, J. B., Strauss, J., Kennedy, J. L., Day, R., Matthews, K., Bakke, P., Gulsvik, A., Lucae, S., Ising, M., Brueckl, T., Horstmann, S., Wichmann, H. E., Rawal, R., Wichmann, H. E., Lamina, C., Dahmen, N., Polasek, O., Kolcic, I., Huffman, J., Campbell, S., Vitart, V., Hayward, C., Wright, A. F., Burnett, M. S., Devaney, J. M., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Epstein, S., Reilly, M. P., Li, M., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Rader, D. J., Ellinghaus, D., Lieb, W., Franke, A., Uda, M., Busonero, F., Terracciano, A., Schlessinger, D., Xiao, X., Scheet, P., St Clair, D., Rujescu, D., Abecasis, G. R., Grabe, H. J., Teumer, A., Völzke, H., Petersmann, A., John, U., Wright, B. J., Thompson, J. R., Balmforth, A. J., Hall, A. S., Samani, N. J., Ahmad, T., Mathew, C. G., Parkes, M., Satsangi, J., Caulfield, M., Munroe, P. B., Dominiczak, A., Worthington, J., Thomson, W., Eyre, S., Barton, A. & Francks, C. Oct 2015 In : The Lancet Respiratory Medicine. 3, 10, p. 769-781 13 p.

    Research output: Contribution to journalArticle

  31. Exploring the role of drug-metabolising enzymes in antidepressant side effects

    Hodgson, K., Tansey, K. E., Uher, R., Dernovšek, M. Z., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Craig, I. W., Aitchison, K. J., Farmer, A., Dobson, R. J. B. & McGuffin, P. Jul 2015 In : Psychopharmacology. 232, 14, p. 2609-2617 9 p.

    Research output: Contribution to journalArticle

  32. A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

    Hung, C-F. , Breen, G. , Czamara, D. , Corre, T. , Wolf, C. , Kloiber, S. , Bergmann, S. , Craddock, N. , Gill, M. , Holsboer, F. , Jones, L. , Jones, I. , Korszun, A. , Kutalik, Z. , Lucae, S. , Maier, W. , Mors, O. , Owen, M. J. , Rice, J. , Rietschel, M. & 10 others Uher, R., Vollenweider, P., Waeber, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Müller-Myhsok, B., Preisig, M., McGuffin, P. & Rivera, M. 17 Apr 2015 In : BMC Medicine. 13, 10 p., 86

    Research output: Contribution to journalArticle

  33. DNA Modification Study of Major Depressive Disorder: Beyond Locus-by-Locus Comparisons

    Oh, G. , Wang, S-C. , Pal, M. , Chen, Z. F. , Khare, T. , Tochigi, M. , Ng, C. , Yang, Y. A. , Kwan, A. , Kaminsky, Z. A. , Mill, J. , Gunasinghe, C. , Tackett, J. L. , Gottesman, I. I. , Willemsen, G. , de Geus, E. J. C. , Vink, J. M. , Slagboom, P. E. , Wray, N. R. , Heath, A. C. & 7 others Montgomery, G. W., Turecki, G., Martin, N. G., Boomsma, D. I., McGuffin, P., Kustra, R. & Petronis, A. 1 Feb 2015 In : Biological Psychiatry. 77, 3, p. 246-255 10 p.

    Research output: Contribution to journalArticle

  34. Phenotypic Association Analyses with Copy Number Variation in Recurrent Depressive Disorder.

    Rucker, J. J. H. , Tansey, K. E. , Rivera, M. , Pinto, D. , Cohen-Woods, S. , Uher, R. , Aitchison, K. J. , Craddock, N. , Owen, M. J. , Jones, L. , Jones, I. , Korszun, A. , Barnes, M. R. , Preisig, M. , Mors, O. , Maier, W. , Rice, J. , Rietschel, M. , Holsboer, F. , Farmer, A. E. & 4 others Craig, I. W., Scherer, S. W., McGuffin, P. & Breen, G. 1 Feb 2015 In : Biological Psychiatry.

    Research output: Contribution to journalArticle

  35. Familiality and SNP heritability of age at onset and episodicity in major depressive disorder

    Ferentinos, P. , Koukounari, A. , Power, R. , Rivera, M. , Uher, R. , Craddock, N. , Owen, M. J. , Korszun, A. , Jones, L. , Jones, I. , Gill, M. , Rice, J. P. , Ising, M. , Maier, W. , Mors, O. , Rietschel, M. , Preisig, M. , Binder, E. B. , Aitchison, K. J. , Mendlewicz, J. & 9 others Souery, D., Hauser, J., Henigsberg, N., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P. & Lewis, C. M. 2015 In : Psychological Medicine. 11 p.

    Research output: Contribution to journalArticle

  36. 2014
  37. Trauma, post-traumatic stress disorder and psychiatric disorders in a middle-income setting: prevalence and comorbidity

    Dorrington, S., Zavos, H., Ball, H., McGuffin, P., Rijsdijk, F., Siribaddana, S., Sumathipala, A. & Hotopf, M. 3 Nov 2014 In : British Journal of Psychiatry. 205, 5, p. 383-389 7 p.

    Research output: Contribution to journalArticle

  38. Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study

    Hung, C-F., Rivera, M., Craddock, N., Owen, M. J., Gill, M., Korszun, A., Maier, W., Mors, O., Preisig, M., Rice, J. P., Rietschel, M., Jones, L., Middleton, L., Aitchison, K. J., Davis, O. S. P., Breen, G., Lewis, C., Farmer, A. & McGuffin, P. Jul 2014 In : British Journal of Psychiatry. 205, 1, p. 24-28 5 p.

    Research output: Contribution to journalArticle

  39. Genetic predictors of antidepressant side effects: A grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study

    Hodgson, K., Uher, R., Crawford, A. A., Lewis, G., O'Donovan, M. C., Keers, R., Dernovsek, M. Z., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Aitchison, K., Farmer, A., Davis, O. & McGuffin, P. Feb 2014 In : Journal of Psychopharmacology. 28, 2, p. 142-150 9 p., N/A

    Research output: Contribution to journalArticle

  40. Investigating the genetic variation underlying episodicity in major depressive disorder: Suggestive evidence for a bipolar contribution

    Ferentinos, P. , Rivera, M. , Ising, M. , Spain, S. L. , Cohen-Woods, S. , Butler, A. W. , Craddock, N. , Owen, M. J. , Korszun, A. , Jones, L. , Jones, I. , Gill, M. , Rice, J. P. , Maier, W. , Mors, O. , Rietschel, M. , Lucae, S. , Binder, E. B. , Preisig, M. , Tozzi, F. & 7 others Muglia, P., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P. & Lewis, C. M. Feb 2014 In : Journal of Affective Disorders. 155, N/A, p. 81-89 9 p., N/A

    Research output: Contribution to journalArticle

  41. Copy number variants and therapeutic response to antidepressant medication in major depressive disorder.

    Tansey, K. E. , Rucker, J. J. H. , Kavanagh, D. H. , Guipponi, M. , Perroud, N. , Bondolfi, G. , Domenici, E. , Evans, D. M. , Hauser, J. , Henigsberg, N. , Jerman, B. , Maier, W. , Mors, O. , O'Donovan, M. , Peters, T. J. , Placentino, A. , Rietschel, M. , Souery, D. , Aitchison, K. J. , Craig, I. & 7 others Farmer, A., Wendland, J. R., Malafosse, A., Lewis, G., Kapur, S., McGuffin, P. & Uher, R. 1 Jan 2014 In : PHARMACOGENOMICS JOURNAL. 14, 4, p. 395-399 5 p.

    Research output: Contribution to journalArticle

  42. Genetic susceptibility for bipolar disorder and response to antidepressants in major depressive disorder

    Tansey, K. E., Guipponi, M., Domenici, E., Lewis, G., Malafosse, A., O'Donovan, M., Wendland, J. R., Lewis, C. M., McGuffin, P. & Uher, R. Jan 2014 In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 165, 1, p. 77-83 7 p., N/A

    Research output: Contribution to journalArticle

  43. A genome-wide association study of anorexia nervosa

    Boraska, V. , Franklin, C. S. , Floyd, J. A. B. , Thornton, L. M. , Huckins, L. M. , Southam, L. , Rayner, N. W. , Tachmazidou, I. , Klump, K. L. , Treasure, J. , Lewis, C. M. , Schmidt, U. , Tozzi, F. , Kiezebrink, K. , Hebebrand, J. , Gorwood, P. , Adan, R. A. H. , Kas, M. J. H. , Favaro, A. , Santonastaso, P. & 31 others Fernández-Aranda, F., Gratacos, M., Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori, A., Van Furth, E. F., Slof-Op 't Landt, M. C. T., Hudson, J. I., Reichborn-Kjennerud, T., Knudsen, G. P. S., Monteleone, P., Kaplan, A. S., Karwautz, A., Hakonarson, H., Berrettini, W. H., Guo, Y., Li, D., Schork, N. J., Davis, O. S. P., Helder, S., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Kalsi, G., Roberts, M., Collier, D. A., The Wellcome Trust Case Control Consortium 3 & Lord, G. 2014 In : Molecular Psychiatry. N/A, N/A, p. N/A N/A

    Research output: Contribution to journalArticle

  44. A genome-wide association study of suicide severity scores in bipolar disorder

    Zai, C. C., Gonçalves, V. F., Tiwari, A. K., Gagliano, S. A., Hosang, G., de Luca, V., Shaikh, S. A., King, N., Chen, Q., Xu, W., Strauss, J., Breen, G., Lewis, C. M., Farmer, A. E., McGuffin, P., Knight, J., Vincent, J. B. & Kennedy, J. L. 2014 In : Journal of psychiatric research. 7 p.

    Research output: Contribution to journalArticle

  45. Chipping away at major depressive disorder.

    Rucker, J. J. H. & McGuffin, P. 2014 In : Genome Biology. 15, 7, p. 421 1 p.

    Research output: Contribution to journalArticle

  46. Investigation of blood mRNA biomarkers for suicidality in an independent sample

    Mullins, N., Hodgson, K., Tansey, K. E., Perroud, N., Maier, W., Mors, O., Rietschel, M., Hauser, J., Henigsberg, N., Souery, D., Aitchison, K., Farmer, A., McGuffin, P., Breen, G., Uher, R. & Lewis, C. M. 2014 In : Translational psychiatry. 4, 4 p., e474

    Research output: Contribution to journalArticle

  47. 2013
  48. Genome-wide association study of co-occurring anxiety in major depression

    Schosser, A. , Butler, A. W. , Uher, R. , Ng, M. Y. , Cohen-Woods, S. , Craddock, N. , Owen, M. J. , Korszun, A. , Gill, M. , Rice, J. , Hauser, J. , Henigsberg, N. , Maier, W. , Mors, O. , Placentino, A. , Rietschel, M. , Souery, D. , Preisig, M. , Craig, I. W. , Farmer, A. E. & 2 others Lewis, C. M. & McGuffin, P. Dec 2013 In : The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 14, 8, p. 611-621 11 p., N/A

    Research output: Contribution to journalArticle

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