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  1. 2019
  2. Converging evidence points towards a role of insulin signaling in regulating compulsive behavior

    van de Vondervoort, I. I. G. M., Amiri, H., Bruchhage, M. M. K., Oomen, C. A., Rustogi, N., Cooper, J. D., van Asten, J. J. A., Heerschap, A., Bahn, S., Williams, S. C. R., Buitelaar, J. K., Poelmans, G. & Glennon, J. C., 12 Sep 2019, In : Translational psychiatry. 9, 1, p. 225

    Research output: Contribution to journalArticle

  3. Classical Human Leukocyte Antigen Alleles and Complement Component 4 Haplotypes Are Not Significantly Associated With Depression

    Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J. P., Choi, S. W., Purves, K. L., Breen, G. D., Air, T. M., Andlauer, T. M. F., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., de Geus, E. J. C. & 34 othersGrabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Lucae, S., Magnusson., P. K. E., McGuffin, P., McIntosh, A., Milaneschi, Y., Lewis, C. M., Mostafavi, S., Muller-Myhsok, B., Pedersen, N. L., Penninx, B. W., Potash, J. B., Preisig, M., Ripke, S., Shi, J., Shyn, S. I., Smoller, J. W., Streit, F., Sullivan, P. F., Tiemeier, H., Uher, R., der Auwera, S. V., Weissman, M. M., O'Reilly, P. F. & Lewis, C. M., 5 Aug 2019, In : Biological psychiatry.

    Research output: Contribution to journalArticle

  4. Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

    Anorexia Nervosa Genetics Initiative, 1 Aug 2019, In : Nature Genetics. 51, 8, p. 1207–1214 8 p.

    Research output: Contribution to journalArticle

  5. Similarities between borderline personality disorder and post traumatic stress disorder: Evidence from resting-state meta-analysis

    Amad, A., Radua, J., Vaiva, G., Williams, S. CR. & Fovet, T., 29 Jul 2019, In : Neuroscience and Biobehavioral Reviews. 105, p. 52-59 8 p.

    Research output: Contribution to journalReview article

  6. Genome-wide burden of rare short deletions is enriched in Major Depressive Disorder in four cohorts

    Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 15 Jun 2019, In : Biological psychiatry. 85, 12, p. 1065-1073 9 p.

    Research output: Contribution to journalArticle

  7. Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 11 Jun 2019, In : Nature Communications. 10, 1, p. 1-18 18 p., 2548.

    Research output: Contribution to journalArticle

  8. Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia

    Deciphering Developmental Disorders Study, UK10K Consortium, NIHR BioResource, Simpson, M. A., Prigmore, E., Jones, P., Armstrong, R., Bennett, C., Berg, J., Bernhard, B., Cooper, N., Cox, H., Flinter, F., Fry, A., Gill, H., Gray, E., Harrison, V., Irving, M., Josifova, D., Langman, C. & 44 othersMohammed, S., Moore, D., Murphy, H., Roberts, J., Tischkowitz, M., Wright, M., Bolton, P., Breen, G., Clement, G., Collier, D., Curran, S., Ellis, P., Evans, D., Hart, D., Hubbard, T., Hysi, P., Jamshidi, Y., Lachance, G., Lopes, M., McGuffin, P., Metrustry, S., Moayyeri, A., Onoufriadis, A., Parr, J. R., Quaye, L., Sharp, S. I., Small, K., Spasic-Boskovic, O., Stevens, E., Valdes, A., Walters, J. T. R., Wang, Y., Bennett, D., Bradley, J. R., Davis, J., Koziell, A., Machado, R., Richards, M., Smith, K., Southgate, L., Thomas, E., Trembath, R., Williamson, C. & Yong, P., 2 May 2019, In : American Journal of Human Genetics. 104, 5, p. 948-956 9 p.

    Research output: Contribution to journalArticle

  9. Neurochemical Effects of Oxytocin in People at Clinical High Risk for Psychosis

    Davies, C., Rutigliano, G., De Micheli, A. I., Stone, J. M., Ramella-Cravaro, V., Provenzani, U., Cappucciati, M., Scutt, E., Paloyelis, Y., Oliver, D. A. P., Murguia, S., Zelaya, F. O., Allen, P., Shergill, S. S., Morrison, P. D., Williams, S. C. R., Taylor, D. M., Lythgoe, D. J., McGuire, P. & Fusar-Poli, P., 1 May 2019, In : European Neuropsychopharmacology. 29, 5, p. 601-615 15 p.

    Research output: Contribution to journalArticle

  10. Verbal Fluency Is Affected by Altered Brain Lateralization in Adults Who Were Born Very Preterm

    Tseng, C-E. J., Froudist-Walsh, S., Kroll, J., Karolis, V., Brittain, P. J., Palamin, N., Clifton, H., Counsell, S. J., Williams, S. C. R., Murray, R. M. & Nosarti, C., 20 Apr 2019, In : eNeuro. 6, 2, e0274-18.2018.

    Research output: Contribution to journalArticle

  11. Functional brain networks and neuroanatomy underpinning nausea severity can predict nausea susceptibility using machine learning

    Ruffle, J. K., Patel, A., Giampietro, V., Howard, M. A., Sanger, G., Andrews, P. L. R., Williams, S. C. R., Aziz, Q. & Farmer, A. D., 15 Mar 2019, In : The Journal of Physiology. 597, 6, p. 1517-1529 13 p.

    Research output: Contribution to journalArticle

  12. Family functioning, trauma exposure and PTSD: A cross sectional study

    Dorrington, S., Zavos, H., Ball, H., McGuffin, P., Sumathipala, A., Siribaddana, S., Rijsdijk, F., Hatch, S. L. & Hotopf, M., 15 Feb 2019, In : Journal of Affective Disorders. 245, p. 645-652 8 p.

    Research output: Contribution to journalArticle

  13. Oxytocin Modulates Hippocampal Perfusion in People at Clinical High Risk for Psychosis

    Davies, C., Paloyelis, Y., Rutigliano, G., Cappucciati, M., De Micheli, A., Ramella-Cravaro, V., Provenzani, U., Antoniades, M., Modinos, G., Oliver, D., Stahl, D., Murguia, S., Zelaya, F., Allen, P., Shergill, S., Morrison, P., Williams, S., Taylor, D., McGuire, P. & Fusar-Poli, P., 9 Jan 2019, In : Neuropsychopharmacology. 44, 7, p. 1300-1309 10 p.

    Research output: Contribution to journalArticle

  14. Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches

    Eating Disorders Working Group of the Psychiatric Genomics Consortium, 1 Jan 2019, In : Biological psychiatry.

    Research output: Contribution to journalArticle

  15. 2018
  16. Hyperperfusion of Frontal White and Subcortical Gray Matter in Autism Spectrum Disorder

    Peterson, B. S., Zargarian, A., Peterson, J. B., Goh, S., Sawardekar, S., Williams, S. C. R., Lythgoe, D. J., Zelaya, F. O. & Bansal, R., 21 Dec 2018, In : Biological psychiatry.

    Research output: Contribution to journalArticle

  17. Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

    Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Eley, T. C., Gaspar, H. A., McGuffin, P., Mullins, N., O'Reilly, P. F., Lewis, C. M. & Breen, G., 20 Dec 2018, In : PLoS ONE. 13, 12, e0209160.

    Research output: Contribution to journalArticle

  18. Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

    Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 1 Dec 2018, In : Communications Biology. 1, 1, 163.

    Research output: Contribution to journalArticle

  19. Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)

    Ren, H., Fabbri, C., Uher, R., Rietschel, M., Mors, O., Henigsberg, N., Hauser, J., Zobel, A., Maier, W., Dernovsek, M. Z., Souery, D., Cattaneo, A., Breen, G., Craig, I. W., Farmer, A. E., McGuffin, P., Lewis, C. M. & Aitchison, K. J., 1 Dec 2018, In : Translational psychiatry. 8, 1, 150.

    Research output: Contribution to journalArticle

  20. No evidence of differences in cognitive control in children with Autism Spectrum Disorder or Obsessive-Compulsive Disorder: an fMRI study

    Gooskens, B., Bos, D. J., Mensen, V. T., Shook, D. A., Bruchhage, M., Naaijen, J., Wolf, I., Brandeis, D., Williams, S. C. R., Buitelaar, J. K., Oranje, B. & Durston, S., 29 Nov 2018, In : Developmental Cognitive Neuroscience.

    Research output: Contribution to journalArticle

  21. The benefit of minocycline on negative symptoms of schizophrenia in patients with recent-onset psychosis (BeneMin): a randomised, double-blind, placebo-controlled trial

    Deakin, B., Suckling, J., Barnes, T. R. E., Byrne, K., Chaudhry, I. B., Dazzan, P., Drake, R. J., Giordano, A., Husain, N., Jones, P. B., Joyce, E., Knox, E., Krynicki, C., Lawrie, S. M., Lewis, S., Lisiecka-Ford, D. M., Nikkheslat, N., Pariante, C. M., Smallman, R., Watson, A. & 4 othersWilliams, S. C. R., Upthegrove, R., Dunn, G. & BeneMin Study team, Nov 2018, In : The lancet. Psychiatry. 5, 11, p. 885-894

    Research output: Contribution to journalArticle

  22. Frontostriatal functional connectivity correlates with repetitive behaviour across autism spectrum disorder and obsessive-compulsive disorder

    Akkermans, S. E. A., Rheinheimer, N., Bruchhage, M. M. K., Durston, S., Brandeis, D., Banaschewski, T., Boecker-Schlier, R., Wolf, I., Williams, S. C. R., Buitelaar, J. K., van Rooij, D., Oldehinkel, M. & TACTICS consortium, 26 Oct 2018, In : Psychological Medicine. p. 1-9 9 p.

    Research output: Contribution to journalArticle

  23. Unravelling the GSK3β-related genotypic interaction network influencing hippocampal volume in recurrent major depressive disorder

    Inkster, B., Simmons, A., Cole, J. H., Schoof, E., Linding, R., Nichols, T., Muglia, P., Holsboer, F., Sämann, P. G., McGuffin, P., Fu, C. H. Y., Miskowiak, K., Matthews, P. M., Zai, G. & Nicodemus, K., 1 Oct 2018, In : Psychiatric Genetics. 28, 5, p. 77-84 8 p.

    Research output: Contribution to journalArticle

  24. Genetic disposition to inflammation and response to antidepressants in major depressive disorder

    Zwicker, A., Fabbri, C., Rietschel, M., Hauser, J., Mors, O., Maier, W., Zobel, A., Farmer, A., Aitchison, K. J., McGuffin, P., Lewis, C. M. & Uher, R., 7 Aug 2018, In : Journal of psychiatric research.

    Research output: Contribution to journalArticle

  25. Alterations in brain microstructure in rats that develop abnormal aggression following peripubertal stress

    Walker, S. E., Wood, T. C., Cash, D., Mesquita, M., Williams, S. C. R. & Sandi, C., Jul 2018, In : European Journal of Neuroscience. 48, 2, p. 1818-1832

    Research output: Contribution to journalArticle

  26. Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

    Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 othersAitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., 28 Jun 2018, In : European Neuropsychopharmacology.

    Research output: Contribution to journalArticle

  27. New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C., Tansey, K., Perlis, R., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 othersBiernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R. & Lewis, C., 22 May 2018, In : The pharmacogenomics journal. 18, p. 413-421

    Research output: Contribution to journalArticle

  28. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S., Bækvad-hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-grauholm, J. & 32 othersCai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-conde, L., Couvy-duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F., 1 May 2018, In : Nature Genetics. 50, 5, p. 668-681

    Research output: Contribution to journalArticle

  29. Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables

    Iniesta, R., Hodgson, K., Stahl, D. R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovšek, M. Z., Souery, D., Dobson, R. M., Aitchison, K. J., Farmer, A. E., McGuffin, P., Lewis, C. M. & Uher, R., 3 Apr 2018, In : Scientific Reports.

    Research output: Contribution to journalArticle

  30. Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology

    Horsburgh, K., Wardlaw, J. M., van Agtmael, T., Allan, S. M., Ashford, M. L. J., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Davis, J. B., Duncombe, J., Farr, T. D., Fowler, J. H., Goense, J., Granata, A., Hall, C. N., Hainsworth, A. H., Harvey, A., Hawkes, C. A. & 26 othersJoutel, A., Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., Macleod, M. R., Macrae, I. M., Markus, H. S., McCabe, C., McColl, B. W., Meakin, P. J., Miller, A., Nedergaard, M., O'Sullivan, M., Quinn, T. J., Rajani, R., Saksida, L. M., Smith, C., Smith, K. J., Touyz, R. M., Trueman, R. C., Wang, T., Williams, A., Williams, S. C. R. & Work, L. M., Apr 2018, In : Clinical Science. 132, 8, p. 851-868 18 p.

    Research output: Contribution to journalArticle

  31. Group II metabotropic glutamate receptor agonist prodrugs LY2979165 and LY2140023 attenuate the functional imaging response to ketamine in healthy subjects

    Mehta, M. A., Schmechtig, A., Kotoula, V., McColm, J., Jackson, K., Brittain, C., Tauscher-Wisniewski, S., Kinon, B. J., Morrison, P. D., Pollak, T., Mant, T., Williams, S. C. R. & Schwarz, A. J., 21 Mar 2018, In : Psychopharmacology.

    Research output: Contribution to journalArticle

  32. Morphology of subcortical brain nuclei is associated with autonomic function in healthy humans

    Ruffle, J. K., Coen, S. J., Giampietro, V., Williams, S. C. R., Apkarian, A. V., Farmer, A. D. & Aziz, Q., Jan 2018, In : Human Brain Mapping. 39, 1, p. 381-392

    Research output: Contribution to journalArticle

  33. 2017
  34. Using fMRI to evaluate the effects of milnacipran on central pain processing in patients with fibromyalgia

    Petzke, F., Jensen, K. B., Kosek, E., Choy, E., Carville, S., Fransson, P., Williams, S. C. R., Marcus, H., Mainguy, Y., Ingvar, M. & Gracely, R. H., 29 Dec 2017, In : Scandinavian Journal of Pain. 4, 2, p. 65-74 10 p.

    Research output: Contribution to journalArticle

  35. Obstructive Sleep Apnoea and Alzheimer’s Disease: in Search of Shared Pathomechanisms

    Polsek, D., Gildeh, N., Cash, D., Winsky-Sommerer, R., Williams, S. C. R., Turkheimer, F., Leschziner, G. D., Morrell, M. J. & Rosenzweig, I., 7 Dec 2017, In : Neuroscience and Biobehavioral Reviews.

    Research output: Contribution to journalArticle

  36. New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 othersBiernacka, J. M., Weinshilboum, R. M., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Uher, R. & Lewis, C. M., 21 Nov 2017, In : The pharmacogenomics journal.

    Research output: Contribution to journalArticle

  37. One year double blind study of high vs low frequency subcallosal cingulate stimulation for depression

    Eitan, R., Fontaine, D., Benoît, M., Giordana, C., Darmon, N., Israel, Z., Linesky, E., Arkadir, D., Ben-Naim, S., Iserlles, M., Bergman, H., Hulse, N., Abdelghani, M., McGuffin, P., Farmer, A., DeLea, P., Ashkan, K. & Lerer, B., 3 Oct 2017, In : Journal of psychiatric research.

    Research output: Contribution to journalArticle

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