The relationship between dopamine receptor blockade and cognitive performance in schizophrenia: A [¹¹C]-raclopride PET study with aripiprazole

Shin, S., Kim, S., Seo, S., Lee, J. S., Howes, O. D., Kim, E. & Kwon, J. S., Dec 2018, In: Translational psychiatry. 8, 1, 87.

Research output: Contribution to journal › Article › peer-review

Neuroinflammation in schizophrenia: meta-analysis of in-vivo microglial imaging studies

Reis Marques, T., Ashok, A. H., Pillinger, T., Veronese, M., Turkheimer, F. E., Dazzan, P., Sommer, I. E. C. & Howes, O. D., 25 Oct 2018, In: Psychological Medicine.

Research output: Contribution to journal › Article › peer-review

Defining the Locus of Dopaminergic Dysfunction in Schizophrenia: A Meta-analysis and Test of the Mesolimbic Hypothesis

McCutcheon, R., Beck, K., Jauhar, S. & Howes, O. D., 17 Oct 2018, In: Schizophrenia Bulletin. 44, 6, p. 1301-1311

Research output: Contribution to journal › Article › peer-review

Increased Resting Hippocampal and Basal Ganglia Perfusion in People at Ultra High Risk for Psychosis: Replication in a Second Cohort

Allen, P., Azis, M., Modinos, G., Bossong, M. G., Bonoldi, I., Samson, C., Quinn, B., Kempton, M. J., Howes, O. D., Stone, J. M., Calem, M., Perez, J., Bhattacharayya, S., Broome, M. R., Grace, A. A., Zelaya, F. & McGuire, P., 17 Oct 2018, In: Schizophrenia Bulletin. 44, 6, p. 1323–1331

Research output: Contribution to journal › Article › peer-review

Dopaminergic basis for signalling belief updates, but not surprise, and the link to paranoia

Nour, M., Dahoun, T., Schwartenbeck, P., Adams, R., FitzGerald, T., Coello, C., Wall, M., Dolan, R. J. & Howes, O. D., 8 Oct 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 43, p. E10167-E10176

Research output: Contribution to journal › Article › peer-review

GABA_A receptor availability is not altered In adults with autism spectrum disorder or in mouse models

Horder, J., Andersson, M., Mendez Hernandez, M. A., Singh, N., Tangen, A., Lundberg, J., Gee, A., Halldin, C., Veronese, M., Bolte, S., Farde, L., Sementa, T., Cash, D., K, H., Spain, D., Turkheimer, F., Mick, I., Selvaraj, S., Nutt, DJ., Lingford-Hughes, A. & 3 others, Howes, O., Murphy, D. G. & Borg, J., 3 Oct 2018, In: Science Translational Medicine. 10, 461, eaam8434.

Research output: Contribution to journal › Article › peer-review

Correction: Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis

Modinos, G., Şimşek, F., Azis, M., Bossong, M., Bonoldi, I., Samson, C., Quinn, B., Perez, J., Broome, M. R., Zelaya, F., Lythgoe, D. J., Howes, O. D., Stone, J. M., Grace, A. A., Allen, P. & McGuire, P., 2 Oct 2018, In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Research output: Contribution to journal › Article › peer-review

The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: a cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study

Jauhar, S., McCutcheon, R., Borgan, F., Veronese, M., Nour, M., Pepper, F., Rogdaki, M., Stone, J., Egerton, A., Turkheimer, F., McGuire, P. & Howes, O. D., 1 Oct 2018, In: The Lancet Psychiatry. 5, 10, p. 816-823 8 p.

Research output: Contribution to journal › Article › peer-review

PET studies of the glial cell marker TSPO in psychosis patients - a meta-analysis using individual participant data

Plavén-Sigray, P., Matheson, G. J., Collste, K., Ashok, A. H., Coughlin, J. M., Howes, O. D., Mizrahi, R., Pomper, M. G., Rusjan, P., Veronese, M., Wang, Y. & Cervenka, S., 15 Sep 2018, In: Biological psychiatry.

Research output: Contribution to journal › Article › peer-review

Correction: Regulation of dopaminergic function: an [F]-DOPA PET apomorphine challenge study in humans

Jauhar, S., Veronese, M., Rogdaki, M., Bloomfield, M., Natesan, S., Turkheimer, F., Kapur, S. & Howes, O. D., 31 Aug 2018, In: Translational psychiatry. 8, 1, p. 171

Research output: Contribution to journal › Article

The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study

Dahoun, T., Pardiñas, A. F., Veronese, M., Bloomfield, M. A. P., Jauhar, S., Bonoldi, I., Froudist-Walsh, S., Nosarti, C., Korth, C., Hennah, W., Walters, J., Prata, D. & Howes, O. D., 26 Jun 2018, In: Human Molecular Genetics. 27, 20, p. 3498-3506

Research output: Contribution to journal › Article › peer-review

Antipsychotic drugs: challenges and future directions

Howes, O. D. & Kaar, S. J., 1 Jun 2018, In: World Psychiatry. 17, 2, p. 170-171 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and perspective on potential models

Pillinger, T., D'Ambrosio, E., McCutcheon, R. & Howes, O. D., May 2018, In: Molecular Psychiatry.

Research output: Contribution to journal › Article › peer-review

Determinants of treatment response in first episode psychosis: an ¹⁸F-DOPA PET study

Jauhar, S., Veronese, M., Nour, M., Rogdaki, M., Hathway, P. E., Turkheimer, F. E., Stone, J., Egerton, A., McGuire, P., Kapur, S. & Howes, O., 20 Apr 2018, In: Molecular Psychiatry. 24, p. 1502–1512

Research output: Contribution to journal › Article › peer-review

Synaptic loss in schizophrenia: a meta-analysis and systematic review of synaptic protein and mRNA measures

Osimo, E. F., Beck, K., Reis Marques, T. & Howes, O. D., 6 Mar 2018, In: Molecular Psychiatry. p. 1-38 38 p.

Research output: Contribution to journal › Article › peer-review

Effect of Citalopram on Emotion Processing in Humans: A Combined 5-HT_1A [¹¹C]CUMI-101 PET and Functional MRI Study

Selvaraj, S., Walker, C., Arnone, D., Cao, B., Faulkner, P., Cowen, P. J., Roiser, J. P. & Howes, O. D., 1 Feb 2018, In: Neuropsychopharmacology. 43, 3, p. 655-664 10 p.

Research output: Contribution to journal › Article › peer-review

Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration

Scott, G., Zetterberg, H., Jolly, A., Cole, J. H., De Simoni, S., Jenkins, P. O., Feeney, C., Owen, D. R., Lingford-Hughes, A., Howes, O., Patel, M. C., Goldstone, A. P., Gunn, R. N., Blennow, K., Matthews, P. M. & Sharp, D. J., Feb 2018, In: Brain : a journal of neurology. 141, 2, p. 459-471 13 p.

Research output: Contribution to journal › Article › peer-review

Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis

Modinos, G., Şimşek, F., Azis, M., Bossong, M., Bonoldi, I., Samson, C., Quinn, B., Perez, J., Broome, M. R., Zelaya, F., Lythgoe, D. J., Howes, O. D., Stone, J. M., Grace, A. A., Allen, P. & McGuire, P., 30 Jan 2018, In: Neuropsychopharmacology.

Research output: Contribution to journal › Article › peer-review

Amygdala Reactivity in Ethnic Minorities and its Relationship to the Social Environment: An fMRI Study

McCutcheon, R., Bloomfield, M. A. P., Dahoun, T., Quinlan, M., Terbeck, S., Mehta, M. & Howes, O., 12 Jan 2018, In: Psychological Medicine. 48, 12, p. 1985-1992

Research output: Contribution to journal › Article › peer-review

Autism spectrum disorder: Consensus guidelines on assessment, treatment and research from the British Association for Psychopharmacology: Consensus guidelines on assessment, treatment and research from the British Association for Psychopharmacology

Howes, O. D., Rogdaki, M., Findon, J. L., Wichers, R. H., Charman, T., King, B. H., Loth, E., McAlonan, G. M., McCracken, J. T., Parr, J. R., Povey, C., Santosh, P., Wallace, S., Simonoff, E. & Murphy, D. G., 1 Jan 2018, In: Journal of Psychopharmacology. 32, 1, p. 3-29 269881117741766.

Research output: Contribution to journal › Article › peer-review

Antipsychotic plasma levels in the assessment of poor treatment response in schizophrenia

McCutcheon, R., Beck, K., D'Ambrosio, E., Donocik, J., Gobjila, C., Jauhar, S., Kaar, S., Pillinger, T., Reis Marques, T., Rogdaki, M. & Howes, O. D., Jan 2018, In: Acta Psychiatrica Scandinavica. 137, 1, p. 39-46

Research output: Contribution to journal › Article › peer-review

The effects of ketamine on dopaminergic function: meta-analysis and review of the implications for neuropsychiatric disorders

Kokkinou, M., Ashok, A. H. & Howes, O. D., Jan 2018, In: Molecular Psychiatry. p. 59-69

Research output: Contribution to journal › Review article › peer-review

The Effects of Antipsychotic Treatment on Presynaptic Dopamine Synthesis Capacity in First-Episode Psychosis: A Positron Emission Tomography Study

Jauhar, S., Veronese, M., Nour, M. M., Rogdaki, M., Hathway, P., Natesan, S., Turkheimer, F., Stone, J., Egerton, A., McGuire, P., Kapur, S. & Howes, O. D., 2018, In: Biological psychiatry.

Research output: Contribution to journal › Article › peer-review