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  1. 2020
  2. Acute heart failure

    Arrigo, M., Jessup, M., Mullens, W., Reza, N., Shah, A. M., Sliwa, K. & Mebazaa, A., 1 Dec 2020, In : Nature Reviews Disease Primers. 6, 1, 16.

    Research output: Contribution to journalReview article

  3. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In : Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticle

  4. Consumption of Stilbenes and Flavonoids is Linked to Reduced Risk of Obesity Independently of Fiber Intake

    Mompeo, O., Spector, T. D., Matey Hernandez, M., Le Roy, C., Istas, G., Le Sayec, M., Mangino, M., Jennings, A., Rodriguez-Mateos, A., Valdes, A. M. & Menni, C., 23 Jun 2020, In : Nutrients. 12, 6

    Research output: Contribution to journalArticle

  5. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 1 Jun 2020, In : HYPERTENSION IN PREGNANCY. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  6. Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, 27 May 2020, In : Nature Communications. 11, 1, 2539.

    Research output: Contribution to journalArticle

  7. A Clinical Risk Score to Identify Patients with COVID-19 at High Risk of Critical Care Admission or Death: An Observational Cohort Study

    Galloway, J., Norton, S., Barker, R. D., Brookes, A., Carey, I., Clarke, B., Jina, R., Reid, C., Russell, M. D., Sneep, R., Sugarman, L., Williams, S., Yates, M., Teo, J. T., Shah, A. & Cantle, F., 18 May 2020, In : Journal of Infection.

    Research output: Contribution to journalArticle

  8. Real-time tracking of self-reported symptoms to predict potential COVID-19

    Menni, C., Valdes, A. M., Freidin, M. B., Sudre, C. H., Nguyen, L. H., Drew, D. A., Ganesh, S., Varsavsky, T., Cardoso, M. J., El-Sayed Moustafa, J. S., Visconti, A., Hysi, P., Bowyer, R. C. E., Mangino, M., Falchi, M., Wolf, J., Ourselin, S., Chan, A. T., Steves, C. J. & Spector, T. D., 11 May 2020, In : Nature Medicine.

    Research output: Contribution to journalArticle

  9. Rapid implementation of mobile technology for real-time epidemiology of COVID-19

    COPE Consortium, Drew, D. A., Nguyen, L. H., Steves, C. J., Menni, C., Freydin, M., Varsavsky, T., Sudre, C. H., Cardoso, M. J., Ourselin, S., Wolf, J., Spector, T. D. & Chan, A. T., 5 May 2020, In : Science.

    Research output: Contribution to journalArticle

  10. Beyond Bacterial Killing: NADPH oxidase 2 is an immunomodulator

    Cellone Trevelin, S., Shah, A. & Lombardi, G., May 2020, In : Immunology Letters. 221, p. 39-48 10 p.

    Research output: Contribution to journalReview article

  11. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In : Thorax.

    Research output: Contribution to journalArticle

  12. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In : Trials. 21, 1, p. 347

    Research output: Contribution to journalArticle

  13. Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)

    Kaura, A., Arnold, A. D., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Melikian, N., Lefroy, D. C. & 6 others, Francis, D. P., Shah, A. M., Kharbanda, R., Perera, D., Patel, R. S. & Mayet, J., 7 Apr 2020, In : Journal of the American Heart Association. 9, 7, p. e013684

    Research output: Contribution to journalArticle

  14. A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation

    Yang, J., Moraga, A., Xu, J., Zhao, Y., Luo, P., Lao, K. H., Margariti, A., Zhao, Q., Ding, W., Wang, G., Zhang, M., Zheng, L., Zhang, Z., Hu, Y., Wang, W., Shen, L., Smith, A., Shah, A. M., Wang, Q. & Zeng, L., Apr 2020, In : Stem Cells. 38, 4, p. 556-573 18 p.

    Research output: Contribution to journalArticle

  15. Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

    Nag, A., Kurushima, Y., Bowyer, R. C. E., Wells, P. M., Weiss, S., Pietzner, M., Kocher, T., Raffler, J., Völker, U., Mangino, M., Spector, T. D., Milburn, M. V., Kastenmüller, G., Mohney, R. P., Suhre, K., Menni, C. & Steves, C. J., 27 Mar 2020, In : Human Molecular Genetics. 29, 5, p. 864-875 12 p., ddz308.

    Research output: Contribution to journalArticle

  16. Cytokine mRNA degradation in cardiomyocytes restrains sterile inflammation in pressure overloaded hearts

    Omiya, S., Omori, Y., Taneike, M., Murakawa, T., Ito, J., Tanada, Y., Nishida, K., Yamaguchi, O., Satoh, T., Shah, A. M., Akira, S. & Otsu, K., 25 Feb 2020, In : Circulation. 141, 8, p. 667-677 11 p.

    Research output: Contribution to journalArticle

  17. Differences between race and sex in measures of hip morphology: a population-based comparative study

    Edwards, K., Leyland, K. M., Sanchez-Santos, M. T., Arden, C. P., Spector, T. D., Nelson, A. E., Jordan, J. M., Nevitt, M., Hunter, D. J. & Arden, N. K., 1 Feb 2020, In : Osteoarthritis and Cartilage. 28, 2, p. 189-200 12 p.

    Research output: Contribution to journalArticle

  18. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

    Delitsikou, V., Jarad, G., Rajaram, R. D., Ino, F., Rutkowski, J. M., Chen, C. D., Santos, C. X. C., Scherer, P. E., Abraham, C. R., Shah, A. M., Feraille, E., Miner, J. H. & de Seigneux, S., 1 Feb 2020, In : Faseb Journal. 34, 2, p. 2087-2104 18 p.

    Research output: Contribution to journalArticle

  19. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In : Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  20. NADPH oxidase 2 mediates myocardial oxygen wasting in obesity

    Hafstad, A. D., Hansen, S. S., Lund, J., Santos, C. X. C., Boardman, N. T., Shah, A. M. & Aasum, E., Feb 2020, In : Antioxidants. 9, 2, 171.

    Research output: Contribution to journalArticle

  21. The incidence and characteristics of accelerated knee osteoarthritis among women: The Chingford cohort

    Driban, J. B., Bannuru, R. R., Eaton, C. B., Spector, T. D., Hart, D. J., McAlindon, T. E., Lu, B., Lo, G. H. & Arden, N. K., 31 Jan 2020, In : BMC MUSCULOSKELETAL DISORDERS. 21, 1, 60.

    Research output: Contribution to journalArticle

  22. An unsupervised learning approach to identify novel signatures of health and disease from multimodal data

    Shomorony, I., Cirulli, E. T., Huang, L., Napier, L. A., Heister, R. R., Hicks, M., Cohen, I. V., Yu, H. C., Swisher, C. L., Schenker-Ahmed, N. M., Li, W., Nelson, K. E., Brar, P., Kahn, A. M., Spector, T. D., Caskey, C. T., Venter, J. C., Karow, D. S., Kirkness, E. F. & Shah, N., 10 Jan 2020, In : Genome medicine. 12, 1, 1 p., 7.

    Research output: Contribution to journalArticle

  23. Celastrol Alleviates Aortic Valve Calcification Via Inhibition of NADPH Oxidase 2 in Valvular Interstitial Cells

    Liu, H., Wang, L., Pan, Y., Wang, X., Ding, Y., Zhou, C., Shah, A. M., Zhao, G. & Zhang, M., 1 Jan 2020, In : JACC: Basic to Translational Science. 5, 1, p. 35-49 15 p.

    Research output: Contribution to journalArticle

  24. Predicting Incident Radiographic Knee Osteoarthritis in Middle-Aged Women Within Four Years: The Importance of Knee-Level Prognostic Factors

    Garriga, C., Sánchez-Santos, M. T., Judge, A., Hart, D., Spector, T., Cooper, C. & Arden, N. K., 1 Jan 2020, In : Arthritis Care and Research. 72, 1, p. 88-97 10 p.

    Research output: Contribution to journalArticle

  25. Red Wine Consumption Associated With Increased Gut Microbiota α-Diversity in 3 Independent Cohorts

    Le Roy, C. I., Wells, P. M., Si, J., Raes, J., Bell, J. T. & Spector, T. D., Jan 2020, In : Gastroenterology. 158, 1, p. 270-272.e2

    Research output: Contribution to journalArticle

  26. 2019
  27. Cardiac monocytes and macrophages after myocardial infarction

    Peet, C., Ivetic, A., Bromage, D. I. & Shah, A. M., 16 Dec 2019, In : Cardiovascular Research. cvz336.

    Research output: Contribution to journalArticle

  28. HLA Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut Microbiome

    Asquith, M., Sternes, P. R., Costello, M. E., Karstens, L., Diamond, S., Martin, T. M., Li, Z., Marshall, M. S., Spector, T. D., le Cao, K. A., Rosenbaum, J. T. & Brown, M. A., 12 Dec 2019, In : Arthritis and Rheumatology. 71, 10, p. 1642-1650 9 p.

    Research output: Contribution to journalArticle

  29. Lifestyle information and commercial weight management groups to support maternal postnatal weight management and positive lifestyle behaviour: the SWAN feasibility randomised controlled trial

    Bick, D., Taylor, C., Bhavnani, V., Healey, A., Seed, P., Roberts, S., Zasada, M., Avery, A., Craig, V., Khazaezadah, N., McMullen, S., O'Connor, S., Oki, B., Oteng Ntim, E., Poston, L. & Ussher, M., 5 Dec 2019, In : BJOG. 27 p.

    Research output: Contribution to journalArticle

  30. A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

    Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmüller, G., Boyd, A., Zierer, J., van den Akker, E. B., Ala-Korpela, M., Amin, N., Demirkan, A., Ghanbari, M., van Heemst, D., Ikram, M. A., van Klinken, J. B., Mooijaart, S. P., Peters, A., Salomaa, V., Sattar, N. & 15 others, Spector, T. D., Tiemeier, H., Verhoeven, A., Waldenberger, M., Würtz, P., Davey Smith, G., Metspalu, A., Perola, M., Menni, C., Geleijnse, J. M., Drenos, F., Beekman, M., Jukema, J. W., van Duijn, C. M. & Slagboom, P. E., 1 Dec 2019, In : Nature Communications. 10, 1, 3346.

    Research output: Contribution to journalArticle

  31. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

    Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P. C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S. J. & 37 others, Bressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M. F., Rotter, J. I., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D. I., Bell, J. T., Demirkan, A. & van Duijn, C. M., 1 Dec 2019, In : Nature Communications. 10, 1, 2581.

    Research output: Contribution to journalArticle

  32. Effect of diet on the gut microbiota: Rethinking intervention duration

    Leeming, E. R., Johnson, A. J., Spector, T. D. & Roy, C. I. L., 1 Dec 2019, In : Nutrients. 11, 12, 2862.

    Research output: Contribution to journalReview article

  33. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

    Borges Manna, L., Ovadia, C., Lövgren-Sandblom, A., Chambers, J., Begum, S., Seed, P., Walker, I., Chappell, L. C., Marschall, H-U. & Williamson, C., 1 Dec 2019, In : BJOG. 126, 13, p. 1633-1640 8 p.

    Research output: Contribution to journalArticle

  34. Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

    van der Spek, A., Broer, L., Draisma, H. H. M., Pool, R., Albrecht, E., Beekman, M., Mangino, M., Raag, M., Nyholt, D. R., Dharuri, H. K., Codd, V., Amin, N., de Geus, E. J. C., Deelen, J., Demirkan, A., Yet, I., Fischer, K., Haller, T., Henders, A. K., Isaacs, A. & 19 others, Medland, S. E., Montgomery, G. W., Mooijaart, S. P., Strauch, K., Suchiman, H. E. D., Vaarhorst, A. A. M., van Heemst, D., Wang-Sattler, R., Whitfield, J. B., Willemsen, G., Wright, M. J., Martin, N. G., Samani, N. J., Metspalu, A., Eline Slagboom, P., Spector, T. D., Boomsma, D. I., van Duijn, C. M. & Gieger, C., 1 Dec 2019, In : Scientific Reports. 9, 1, 11623.

    Research output: Contribution to journalArticle

  35. Novel genetic loci affecting facial shape variation in humans

    International Visible Trait Genetics (VisiGen) Consortium, 26 Nov 2019, In : eLife. 8, e49898.

    Research output: Contribution to journalArticle

  36. Semantic computational analysis of anticoagulation use in atrial fibrillation from real world data

    Bean, D., Teo, J., Wu, H., Oliveira, R., Patel, R., Bendayan, R., Shah, A. M., Dobson, R. J. B. & Scott, P. A., 25 Nov 2019, In : PLOS One. 14, 11, e0225625.

    Research output: Contribution to journalArticle

  37. Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres

    Kaura, A., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F., O'Sullivan, M., Kharbanda, R., Lord, G. M., Melikian, N., Patel, R. S. & 4 others, Perera, D., Shah, A. M., Francis, D. P. & Mayet, J., 20 Nov 2019, In : BMJ (Clinical research ed.). 367, p. l6055 l6055.

    Research output: Contribution to journalArticle

  38. Prelamin A mediates myocardial inflammation in dilated and HIV-Associated cardiomyopathies

    Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M. A., Hayward, R., Ahmad, S. M., Vizcay-barrena, G., Protti, A., Zammit, P. S., Dos Remedios, C. G., Ehler, E., Shah, A. M. & Shanahan, C. M., 14 Nov 2019, In : JCI Insight. 4, 22, e126315.

    Research output: Contribution to journalArticle

  39. Pregnancy-related Acute Kidney Injury in pre-eclampsia: risk factors and renal outcomes

    Conti-Ramsden, F. I., Nathan, H. L., De Greeff, A., Hall, D. R., Seed, P. T., Chappell, L. C., Shennan, A. H. & Bramham, K., Nov 2019, In : Hypertension. 74, 5, p. 1144–1151 8 p.

    Research output: Contribution to journalArticle

  40. Therapies to limit myocardial injury in animal models of myocarditis: a systematic review and meta-analysis

    Silverblatt, J. A., Ziff, O. J., Dancy, L., Daniel, A., Carter, B. R., Scott, P. A., Sado, D., Shah, A. M. & Bromage, D. I., Nov 2019, In : Basic Research in Cardiology. 114, 6, 48.

    Research output: Contribution to journalArticle

  41. Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns

    Menni, C., McCallum, L., Pietzner, M., Zierer, J. B., Aman, A., Suhre, K., Mohney, R., Mangino, M., Friedrich, N., Spector, T. D. & Padmanabhan, S., 21 Oct 2019, In : Scientific Reports. 9, 1, 8 p., 15088.

    Research output: Contribution to journalArticle

  42. Interplay between the human gut microbiome and host metabolism

    Visconti, A., Le Roy, C. I., Rosa, F., Martin, T. C., Mohney, R. P., Weizhong, L., de Rinaldis, E., Bell, J. T., Venter, J. C., Nelson, K. E., Spector, T. D. & Falchi, M., 3 Oct 2019, In : Nature Communications. 10, 1, 1 p., 4505.

    Research output: Contribution to journalArticle

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