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Research Outputs

  1. 2020
  2. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In : Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticle

  3. MRI Measurement of Placental Perfusion and Oxygen Saturation in Early Onset Fetal Growth Restriction

    Aughwane, R., Mufti, N., Flouri, D., Maksym, K., Spencer, R., Sokolska, M., Kendall, G., Atkinson, D., Bainbridge, A., Deprest, J., Vercauteren, T., Ourselin, S., David, A. L. & Melbourne, A., 30 Jun 2020, In : BJOG.

    Research output: Contribution to journalArticle

  4. Consumption of Stilbenes and Flavonoids is Linked to Reduced Risk of Obesity Independently of Fiber Intake

    Mompeo, O., Spector, T. D., Matey Hernandez, M., Le Roy, C., Istas, G., Le Sayec, M., Mangino, M., Jennings, A., Rodriguez-Mateos, A., Valdes, A. M. & Menni, C., 23 Jun 2020, In : Nutrients. 12, 6

    Research output: Contribution to journalArticle

  5. Neuropsychiatric Disease Classification Using Functional Connectomics -- Results of the Connectomics in NeuroImaging Transfer Learning Challenge

    Schirmer, M. D., Venkataraman, A., Rekik, I., Kim, M., Mostofsky, S., Nebel, M. B., Rosch, K., Seymour, K., Crocetti, D., Irzan, H., Hütel, M., Ourselin, S., Marlow, N., Melbourne, A., Levchenko, E., Zhou, S., Kunda, M., Lu, H., Dvornek, N. C., Zhuang, J. & 5 others, Pinto, G., Samal, S., Bernal-Rusiel, J. L., Pienaar, R. & Chung, A. W., 5 Jun 2020, In : arXiv.

    Research output: Contribution to journalArticle

  6. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 1 Jun 2020, In : HYPERTENSION IN PREGNANCY. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  7. Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, 27 May 2020, In : Nature Communications. 11, 1, 2539.

    Research output: Contribution to journalArticle

  8. Real-time tracking of self-reported symptoms to predict potential COVID-19

    Menni, C., Valdes, A. M., Freidin, M. B., Sudre, C. H., Nguyen, L. H., Drew, D. A., Ganesh, S., Varsavsky, T., Cardoso, M. J., El-Sayed Moustafa, J. S., Visconti, A., Hysi, P., Bowyer, R. C. E., Mangino, M., Falchi, M., Wolf, J., Ourselin, S., Chan, A. T., Steves, C. J. & Spector, T. D., 11 May 2020, In : Nature Medicine.

    Research output: Contribution to journalArticle

  9. Rapid implementation of mobile technology for real-time epidemiology of COVID-19

    COPE Consortium, Drew, D. A., Nguyen, L. H., Steves, C. J., Menni, C., Freydin, M., Varsavsky, T., Sudre, C. H., Cardoso, M. J., Ourselin, S., Wolf, J., Spector, T. D. & Chan, A. T., 5 May 2020, In : Science.

    Research output: Contribution to journalArticle

  10. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In : Thorax.

    Research output: Contribution to journalArticle

  11. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In : Trials. 21, 1, p. 347

    Research output: Contribution to journalArticle

  12. Computer-Assisted Versus Manual Planning for Stereotactic Brain Biopsy: A Retrospective Comparative Pilot Study

    Marcus, H. J., Vakharia, V. N., Sparks, R., Rodionov, R., Kitchen, N., McEvoy, A. W., Miserocchi, A., Thorne, L., Ourselin, S. & Duncan, J. S., 1 Apr 2020, In : Operative neurosurgery (Hagerstown, Md.). 18, 4, p. 417-422 6 p.

    Research output: Contribution to journalArticle

  13. Generalised boundary shift integral for longitudinal assessment of spinal cord atrophy

    Prados, F., Moccia, M., Johnson, A., Yiannakas, M., Grussu, F., Cardoso, M. J., Ciccarelli, O., Ourselin, S., Barkhof, F. & Wheeler-Kingshott, C., 1 Apr 2020, In : NeuroImage. 209, 116489.

    Research output: Contribution to journalArticle

  14. Intrapapillary capillary loop classification in magnification endoscopy: open dataset and baseline methodology

    García-Peraza-Herrera, L. C., Everson, M., Lovat, L., Wang, H-P., Wang, W. L., Haidry, R., Stoyanov, D., Ourselin, S. & Vercauteren, T., 1 Apr 2020, In : International Journal of Computer Assisted Radiology and Surgery. 15, 4, p. 651-659 9 p.

    Research output: Contribution to journalArticle

  15. Neurosense: deep sensing of full or near-full coverage head/brain scans in human magnetic resonance imaging

    Kanber, B., Ruffle, J., Cardoso, J., Ourselin, S. & Ciccarelli, O., 1 Apr 2020, In : Neuroinformatics. 18, 2, p. 333-336 4 p.

    Research output: Contribution to journalComment/debate

  16. Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

    Nag, A., Kurushima, Y., Bowyer, R. C. E., Wells, P. M., Weiss, S., Pietzner, M., Kocher, T., Raffler, J., Völker, U., Mangino, M., Spector, T. D., Milburn, M. V., Kastenmüller, G., Mohney, R. P., Suhre, K., Menni, C. & Steves, C. J., 27 Mar 2020, In : Human Molecular Genetics. 29, 5, p. 864-875 12 p., ddz308.

    Research output: Contribution to journalArticle

  17. An automated framework for localization, segmentation and super-resolution reconstruction of fetal brain MRI

    Ebner, M., Wang, G., Li, W., Aertsen, M., Patel, P. A., Aughwane, R., Melbourne, A., Doel, T., Dymarkowski, S., De Coppi, P., David, A. L., Deprest, J., Ourselin, S. & Vercauteren, T., 1 Feb 2020, In : NeuroImage. 206, 116324.

    Research output: Contribution to journalArticle

  18. Differences between race and sex in measures of hip morphology: a population-based comparative study

    Edwards, K., Leyland, K. M., Sanchez-Santos, M. T., Arden, C. P., Spector, T. D., Nelson, A. E., Jordan, J. M., Nevitt, M., Hunter, D. J. & Arden, N. K., 1 Feb 2020, In : Osteoarthritis and Cartilage. 28, 2, p. 189-200 12 p.

    Research output: Contribution to journalArticle

  19. PET/MRI attenuation estimation in the lung: A review of past, present, and potential techniques

    Lillington, J., Brusaferri, L., Kläser, K., Shmueli, K., Neji, R., Hutton, B. F., Fraioli, F., Arridge, S., Cardoso, M. J., Ourselin, S., Thielemans, K. & Atkinson, D., 1 Feb 2020, In : Medical physics. 47, 2, p. 790-811 22 p.

    Research output: Contribution to journalReview article

  20. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In : Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  21. The incidence and characteristics of accelerated knee osteoarthritis among women: The Chingford cohort

    Driban, J. B., Bannuru, R. R., Eaton, C. B., Spector, T. D., Hart, D. J., McAlindon, T. E., Lu, B., Lo, G. H. & Arden, N. K., 31 Jan 2020, In : BMC MUSCULOSKELETAL DISORDERS. 21, 1, 60.

    Research output: Contribution to journalArticle

  22. An unsupervised learning approach to identify novel signatures of health and disease from multimodal data

    Shomorony, I., Cirulli, E. T., Huang, L., Napier, L. A., Heister, R. R., Hicks, M., Cohen, I. V., Yu, H. C., Swisher, C. L., Schenker-Ahmed, N. M., Li, W., Nelson, K. E., Brar, P., Kahn, A. M., Spector, T. D., Caskey, C. T., Venter, J. C., Karow, D. S., Kirkness, E. F. & Shah, N., 10 Jan 2020, In : Genome medicine. 12, 1, 1 p., 7.

    Research output: Contribution to journalArticle

  23. A 30-Year Clinical and Magnetic Resonance Imaging Observational Study of Multiple Sclerosis and Clinically Isolated Syndromes

    Chung, K. K., Altmann, D., Barkhof, F., Miszkiel, K., Brex, P. A., O'Riordan, J., Ebner, M., Prados, F., Cardoso, M. J., Vercauteren, T., Ourselin, S., Thompson, A., Ciccarelli, O. & Chard, D. T., 1 Jan 2020, In : Annals of Neurology. 87, 1, p. 63-74 12 p.

    Research output: Contribution to journalArticle

  24. Computer-assisted planning for minimally invasive anterior two-thirds laser corpus callosotomy: A feasibility study with probabilistic tractography validation: Automated laser callosotomy trajectory planning

    Vakharia, V. N., Sparks, R. E., Vos, S. B., Bezchlibnyk, Y., Mehta, A. D., Willie, J. T., Wu, C., Sharan, A., Ourselin, S. & Duncan, J. S., 1 Jan 2020, In : NeuroImage: Clinical. 25, 102174.

    Research output: Contribution to journalArticle

  25. Ex vivo assessment of the optical characteristics of human brain and tumour tissue

    Shapey, J., Xie, Y., Nabavi, E., Ebner, M., Maneas, E., Saeed, S. R., Dorward, N., Kitchen, N., Desjardins, A. E., Ourselin, S., Jaunmuktane, Z., Brandner, S., Bradford, R. & Vercauteren, T., 1 Jan 2020, Label-Free Biomedical Imaging and Sensing (LBIS) 2020. Shaked, N. T. & Hayden, O. (eds.). SPIE, 112510J. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11251).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  26. Longitudinal (18F)AV-1451 PET imaging in a patient with frontotemporal dementia due to a Q351R MAPT mutation

    Convery, R. S., Jiao, J., Clarke, M. T. M., Moore, K. M., Koriath, C. A. M., Woollacott, I. O. C., Weston, P. S. J., Gunn, R., Rabiner, I., Cash, D. M., Rossor, M. N., Warren, J. D., Fox, N. C., Ourselin, S., Bocchetta, M. & Rohrer, J. D., 1 Jan 2020, In : Journal of Neurology, Neurosurgery and Psychiatry. 91, 1, p. 106-108 3 p.

    Research output: Contribution to journalLetter

  27. Predicting Incident Radiographic Knee Osteoarthritis in Middle-Aged Women Within Four Years: The Importance of Knee-Level Prognostic Factors

    Garriga, C., Sánchez-Santos, M. T., Judge, A., Hart, D., Spector, T., Cooper, C. & Arden, N. K., 1 Jan 2020, In : Arthritis Care and Research. 72, 1, p. 88-97 10 p.

    Research output: Contribution to journalArticle

  28. Towards automated spine mobility quantification: a locally rigid ct to x-ray registration framework

    Drobny, D., Ranzini, M., Isaac, A., Vercauteren, T., Ourselin, S., Choi, D. & Modat, M., 1 Jan 2020, Biomedical Image Registration - 9th International Workshop, WBIR 2020, Proceedings. Spiclin, Z., McClelland, J., Kybic, J. & Goksel, O. (eds.). SPRINGER, p. 67-77 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 12120 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  29. Automated postoperative muscle assessment of hip arthroplasty patients using multimodal imaging joint segmentation

    Ranzini, M. B. M., Henckel, J., Ebner, M., Cardoso, M. J., Isaac, A., Vercauteren, T., Ourselin, S., Hart, A. & Modat, M., Jan 2020, In : Computer Methods and Programs in Biomedicine. 183, p. 105062 105062.

    Research output: Contribution to journalArticle

  30. Red Wine Consumption Associated With Increased Gut Microbiota α-Diversity in 3 Independent Cohorts

    Le Roy, C. I., Wells, P. M., Si, J., Raes, J., Bell, J. T. & Spector, T. D., Jan 2020, In : Gastroenterology. 158, 1, p. 270-272.e2

    Research output: Contribution to journalArticle

  31. Basal forebrain atrophy in frontotemporal dementia

    Convery, R. S., Neason, M. R., Cash, D. M., Cardoso, M. J., Modat, M., Ourselin, S., Warren, J. D., Rohrer, J. D. & Bocchetta, M., 2020, In : NeuroImage: Clinical. 26, 102210.

    Research output: Contribution to journalArticle

  32. Front Cover: Photoacoustic imaging of the human placental vasculature (J. Biophotonics 4/2020)

    Maneas, E., Aughwane, R., Huynh, N., Xia, W., Ansari, R., Kuniyil Ajith Singh, M., Hutchinson, J. C., Sebire, N. J., Arthurs, O. J., Deprest, J., Ourselin, S., Beard, P. C., Melbourne, A., Vercauteren, T., David, A. L. & Desjardins, A. E., 2020, In : Journal of biophotonics. 13, 4, p. e202070009

    Research output: Contribution to journalArticle

  33. 2019
  34. HLA Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut Microbiome

    Asquith, M., Sternes, P. R., Costello, M. E., Karstens, L., Diamond, S., Martin, T. M., Li, Z., Marshall, M. S., Spector, T. D., le Cao, K. A., Rosenbaum, J. T. & Brown, M. A., 12 Dec 2019, In : Arthritis and Rheumatology. 71, 10, p. 1642-1650 9 p.

    Research output: Contribution to journalArticle

  35. An artificial intelligence framework for automatic segmentation and volumetry of vestibular schwannomas from contrast-enhanced T1-weighted and high-resolution T2-weighted MRI

    Shapey, J., Wang, G., Dorent, R., Dimitriadis, A., Li, W., Paddick, I., Kitchen, N., Bisdas, S., Saeed, S. R., Ourselin, S., Bradford, R. & Vercauteren, T., 6 Dec 2019, In : Journal of Neurosurgery. p. 1-9 9 p.

    Research output: Contribution to journalArticle

  36. Lifestyle information and commercial weight management groups to support maternal postnatal weight management and positive lifestyle behaviour: the SWAN feasibility randomised controlled trial

    Bick, D., Taylor, C., Bhavnani, V., Healey, A., Seed, P., Roberts, S., Zasada, M., Avery, A., Craig, V., Khazaezadah, N., McMullen, S., O'Connor, S., Oki, B., Oteng Ntim, E., Poston, L. & Ussher, M., 5 Dec 2019, In : BJOG. 27 p.

    Research output: Contribution to journalArticle

  37. A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

    Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmüller, G., Boyd, A., Zierer, J., van den Akker, E. B., Ala-Korpela, M., Amin, N., Demirkan, A., Ghanbari, M., van Heemst, D., Ikram, M. A., van Klinken, J. B., Mooijaart, S. P., Peters, A., Salomaa, V., Sattar, N. & 15 others, Spector, T. D., Tiemeier, H., Verhoeven, A., Waldenberger, M., Würtz, P., Davey Smith, G., Metspalu, A., Perola, M., Menni, C., Geleijnse, J. M., Drenos, F., Beekman, M., Jukema, J. W., van Duijn, C. M. & Slagboom, P. E., 1 Dec 2019, In : Nature Communications. 10, 1, 3346.

    Research output: Contribution to journalArticle

  38. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

    Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P. C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S. J. & 37 others, Bressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M. F., Rotter, J. I., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D. I., Bell, J. T., Demirkan, A. & van Duijn, C. M., 1 Dec 2019, In : Nature Communications. 10, 1, 2581.

    Research output: Contribution to journalArticle

  39. Effect of diet on the gut microbiota: Rethinking intervention duration

    Leeming, E. R., Johnson, A. J., Spector, T. D. & Roy, C. I. L., 1 Dec 2019, In : Nutrients. 11, 12, 2862.

    Research output: Contribution to journalReview article

  40. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

    Borges Manna, L., Ovadia, C., Lövgren-Sandblom, A., Chambers, J., Begum, S., Seed, P., Walker, I., Chappell, L. C., Marschall, H-U. & Williamson, C., 1 Dec 2019, In : BJOG. 126, 13, p. 1633-1640 8 p.

    Research output: Contribution to journalArticle

  41. Evaluation of algorithms for Multi-Modality Whole Heart Segmentation: An open-access grand challenge

    Zhuang, X., Li, L., Payer, C., Štern, D., Urschler, M., Heinrich, M. P., Oster, J., Wang, C., Smedby, Ö., Bian, C., Yang, X., Heng, P-A., Mortazi, A., Bagci, U., Yang, G., Sun, C., Galisot, G., Ramel, J-Y., Brouard, T., Tong, Q. & 14 others, Si, W., Liao, X., Zeng, G., Shi, Z., Zheng, G., Wang, C., MacGillivray, T., Newby, D., Rhode, K., Ourselin, S., Mohiaddin, R., Keegan, J., Firmin, D. & Yang, G., 1 Dec 2019, In : Medical Image Analysis. 58, p. 101537 101537.

    Research output: Contribution to journalArticle

  42. Learning to see the invisible: A data-driven approach to finding the underlying patterns of abnormality in visually normal brain magnetic resonance images in patients with temporal lobe epilepsy

    Bennett, O. F., Kanber, B., Hoskote, C., Cardoso, M. J., Ourselin, S., Duncan, J. S. & Winston, G. P., 1 Dec 2019, In : Epilepsia. 60, 12, p. 2499-2507 9 p.

    Research output: Contribution to journalArticle

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