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Research Outputs

  1. 2016
  2. Placental Growth Factor (PlGF) in Women with Suspected Pre-Eclampsia Prior to 35 Weeks' Gestation: A Budget Impact Analysis

    Duckworth, S., Chappell, L. C., Seed, P. T., Mackillop, L., Shennan, A. H. & Hunter, R., 14 Oct 2016, In : PLoS ONE. 11, 10, p. e0164276 12 p.

    Research output: Contribution to journalArticle

  3. Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice

    Swain, L., Kesemeyer, A., Meyer-Roxlau, S., Vettel, C., Zieseniss, A., Güntsch, A., Jatho, A., Becker, A., Nanadikar, M. S., Morgan, B., Dennerlein, S., Shah, A., El-Armouche, A., Nikolaev, V. O. & Katschinski, D. M., 14 Oct 2016, In : Circulation Research. 119, 9, p. 1004-1016 13 p.

    Research output: Contribution to journalArticle

  4. Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

    Trevelin, S. C., Dos Santos, C. X., Ferreira, R. G., de Sá Lima, L., Silva, R. L., Scavone, C., Curi, R., Alves-Filho, J. C., Cunha, T. M., Roxo-Júnior, P., Cervi, M-C., Laurindo, F. R. M., Hothersall, J. S., Cobb, A. M., Zhang, M., Ivetic, A., Shah, A. M., Lopes, L. R. & Cunha, F. Q., 4 Oct 2016, In : Scientific Reports. 6, 34581.

    Research output: Contribution to journalArticle

  5. CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

    Prior, K-K., Leisegang, M. S., Josipovic, I., Löwe, O., Shah, A. M., Weissmann, N., Schröder, K. & Brandes, R. P., Oct 2016, In : Redox Biology. 9, p. 287–295

    Research output: Contribution to journalArticle

  6. Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

    Barallobre-Barreiro, J., Gupta, S. K., Zoccarato, A., Kitazume-Taneike, R., Fava, M., Yin, X., Werner, T., Hirt, M. N., Zampetaki, A., Viviano, A., Chong, M., Bern, M., Kourliouros, A., Domenech, N., Willeit, P., Shah, A. M., Jahangiri, M., Schaefer, L., Fischer, J. W., Iozzo, R. V. & 6 others, Viner, R., Thum, T., Heineke, J., Kichler, A., Otsu, K. & Mayr, M., 13 Sep 2016, In : Circulation (Baltimore). 134, 11, p. 817-832 16 p.

    Research output: Contribution to journalArticle

  7. Magnetic Drug Targeting: Preclinical in Vivo Studies, Mathematical Modeling, and Extrapolation to Humans

    Al-Jamal, K. T., Bai, J., Tzu-Wen Wang, J., Protti, A., Southern, P., Bogart, L., Heidari, H., Li, X., Cakebread, A., Asker, D., Al-Jamal, W. T., Shah, A., Bals, S., Sosabowski, J. & Pankhurst, Q. A., 19 Aug 2016, In : Nano Letters. 16, 9, p. 5652-5660

    Research output: Contribution to journalLetter

  8. Molecular mechanisms linking autonomic dysfunction and impaired cardiac contractility in critical illness

    Ackland, G. L., Whittle, J., Toner, A., Machhada, A., Del Arroyo, A. G., Sciuso, A., Jenkins, N., Dyson, A., Struthers, R., Sneyd, J. R., Minto, G., Singer, M., Shah, A. & Gourine, A. V., 1 Aug 2016, In : Critical Care Medicine. 44, 8, p. e614-e624

    Research output: Contribution to journalArticle

  9. Potential Effect of Brexit on Cardiovascular Translational Science

    Shah, A. M. & Mann, D. L., 1 Aug 2016, In : JACC: Basic to Translational Science. 1, 5, p. 416-417 2 p.

    Research output: Contribution to journalArticle

  10. Diagnostic Biomarkers in Women With Suspected Preeclampsia in a Prospective Multicenter Study

    Duckworth, S., Griffin, M., Seed, P. T., North, R., Myers, J., Mackillop, L., Simpson, N., Waugh, J., Anumba, D., Kenny, L. C., Redman, C. W. G., Shennan, A. H. & Chappell, L. C., 7 Jul 2016, In : Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  11. 9 Pregnancy and chronic hypertension: Nifedipine vs labetalol as antihypertensive treatment (the panda study): Anti-hypertensive medications

    Webster, L., Myers, J., Nelson-piercy, C., Watt-Coote, I., Wiesender, C., Seed, P. T. & Chappell, L. C., Jul 2016, In : Pregnancy Hypertension. 6, 3, p. 141 1 p.

    Research output: Contribution to journalMeeting abstract

  12. Heart failure-potential new targets for therapy

    Nabeebaccus, A., Zheng, S. & Shah, A. M., 30 Jun 2016, In : British Medical Bulletin. 119, 1, p. 99-110

    Research output: Contribution to journalArticle

  13. Hysteroscopy in recurrent in-vitro fertilisation failure (TROPHY): a multicentre, randomised controlled trial

    El-Toukhy, T., Campo, R., Khalaf, Y., Tabanelli, C., Gianaroli, L., Gordts, S. S., Gordts, S., Mestdagh, G., Mardesic, T., Voboril, J., Marchino, G. L., Benedetto, C., Al-Shawaf, T., Sabatini, L., Seed, P. T., Gergolet, M., Grimbizis, G., Harb, H. & Coomarasamy, A., 25 Jun 2016, In : Lancet. 387, 10038, p. 2614-2621 8 p.

    Research output: Contribution to journalArticle

  14. PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation

    Coomarasamy, A., Williams, H., Truchanowicz, E., Seed, P. T., Small, R., Quenby, S., Gupta, P., Dawood, F., Koot, Y. E., Atik, R. B., Bloemenkamp, K. W., Brady, R., Briley, A., Cavallaro, R., Cheong, Y. C., Chu, J., Eapen, A., Essex, H., Ewies, A., Hoek, A. & 18 others, Kaaijk, E. M., Koks, C. A., Li, T-C., MacLean, M., Mol, B. W., Moore, J., Parrott, S., Ross, J. A., Sharpe, L., Stewart, J., Trépel, D., Vaithilingam, N., Farquharson, R. G., Kilby, M. D., Khalaf, Y., Goddijn, M., Regan, L. & Rai, R., May 2016, In : Health technology assessment (Winchester, England). 20, 41, p. 1-92 92 p.

    Research output: Contribution to journalArticle

  15. The Shortening of MWNT-SPION Hybrids by Steam Treatment Improves Their Magnetic Resonance Imaging Properties In Vitro and In Vivo

    Cabana, L., Bourgognon, M., Wang, J. T. -W., Protti, A., Klippstein, R., de Rosales, R. T. M., Shah, A. M., Fontcuberta, J., Tobías-Rossell, E., Sosabowski, J. K., Al-Jamal, K. T. & Tobias, G., 15 Apr 2016, In : Small.

    Research output: Contribution to journalArticle

  16. The endoplasmic reticulum chaperone calnexin is a NADPH oxidase NOX4 interacting protein

    Prior, K. K., Wittig, I., Leisegang, M. S., Groenendyk, J., Weissmann, N., Michalak, M., Jansen-Dürr, P., Shah, A. M. & Brandes, R. P., 25 Mar 2016, In : Journal of Biological Chemistry. 291, 13, p. 7045-7059 15 p.

    Research output: Contribution to journalArticle

  17. Redox Signaling In The Cardiomyocyte: From Physiology To Failure

    Santos, C. XC., Raza, S., Shah, A. M. & [Unknown], FM., 14 Mar 2016, In : International Journal of Biochemistry and Cell Biology.

    Research output: Contribution to journalArticle

  18. Mutual regulation of epicardial adipose tissue and myocardial redox state by PPAR-γ/adiponectin signalling

    Antonopoulos, A. S., Margaritis, M., Verheule, S., Recalde, A., Sanna, F., Herdman, L., Psarros, C., Nasrallah, H., Coutinho, P., Akoumianakis, I., Brewer, A. C., Sayeed, R., Krasopoulos, G., Petrou, M., Tarun, A., Tousoulis, D., Shah, A. M., Casadei, B., Channon, K. M. & Antoniades, C., 4 Mar 2016, In : Circulation Research. 118, 5, p. 842-855 14 p.

    Research output: Contribution to journalArticle

  19. Vital Sign Prediction of Adverse Maternal Outcomes in Women with Hypovolemic Shock: The Role of Shock Index

    El Ayadi, A. M., Nathan, H. L., Seed, P. T., Butrick, E. A., Hezelgrave, N. L., Shennan, A. H. & Miller, S., 22 Feb 2016, In : PLoS ONE. 11, 2, p. e0148729

    Research output: Contribution to journalArticle

  20. Ambulatory heart rate range predicts mode-specific mortality and hospitalisation in chronic heart failure

    Cubbon, R. M., Ruff, N., Groves, D., Eleuteri, A., Denby, C., Kearney, L., Ali, N., Walker, A. M. N., Jamil, H., Gierula, J., Gale, C. P., Batin, P. D., Nolan, J., Shah, A. M., Fox, K. A. A., Sapsford, R. J., Witte, K. K. & Kearney, M. T., 1 Feb 2016, In : Heart. 102, 3, p. 223-229 7 p.

    Research output: Contribution to journalArticle

  21. NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells

    Jayavelu, A. K., Müller, J. P., Bauer, R., Böhmer, S. A., Lässig, J., Cerny-Reiterer, S., Sperr, W. R., Valent, P., Maurer, B., Moriggl, R., Schröder, K., Shah, A. M., Fischer, M., Scholl, S., Barth, J., Oellerich, T., Berg, T., Serve, H., Frey, S., Fischer, T. & 2 others, Heidel, F. H. & Böhmer, F. D., 1 Feb 2016, In : Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 30, 2, p. 473-483 11 p.

    Research output: Contribution to journalArticle

  22. Quantitative Fetal Fibronectin at 18 Weeks of Gestation to Predict Preterm Birth in Asymptomatic High-Risk Women

    Hezelgrave Elliott, N., Abbott, D. S., Radford, S. K., Seed, P. T., Girling, J. C., Filmer, J., Tribe, R. M. & Shennan, A. H., 1 Feb 2016, In : Obstetrics and Gynecology. 127, 2, p. 255-263 9 p.

    Research output: Contribution to journalArticle

  23. Transcriptional regulation of cystathionine-γ-lyase in endothelial cells by NADPH oxidase 4-dependent signaling

    Mistry, R. K., Murray, T. V. A., Prysyazhna, O., Martin, D., Burgoyne, J., Santos, C., Eaton, P., Shah, A. M. & Brewer, A. C., 22 Jan 2016, In : Journal of Biological Chemistry. 291, 4, p. 1774-1788 15 p.

    Research output: Contribution to journalArticle

  24. Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling

    Santos, C. X., Hafstad, A. D., Beretta, M., Zhang, M., Molenaar, C., Kopec, J., Fotinou, D., Murray, T. V., Cobb, A. M., Martin, D., Zeh Silva, M., Anilkumar, N., Schröder, K., Shanahan, C. M., Brewer, A. C., Brandes, R. P., Blanc, E., Parsons, M., Belousov, V., Cammack, R. & 3 others, Hider, R. C., Steiner, R. A. & Shah, A. M., 18 Jan 2016, In : The EMBO journal. 35, 2, p. 115-236

    Research output: Contribution to journalArticle

  25. Triple-Modal Imaging of Magnetically-Targeted Nanocapsules in Solid Tumours In Vivo

    Bai, J., Wang, J. T-W., Rubio, N., Protti, A., Heidari, H., Elgogary, R., Southern, P., Al-Jamal, W. T., Sosabowski, J., Shah, A. M., Bals, S., Pankhurst, Q. A. & Al-Jamal, K. T., Jan 2016, In : Theranostics. 6, 3, p. 342-56 15 p.

    Research output: Contribution to journalArticle

  26. 2015
  27. Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum

    Abu-Hayyeh, S., Ovadia, C., Lieu, T., Jensen, D. D., Chambers, J., Dixon, P. H., Lövgren-Sandblom, A., Bolier, R., Tolenaars, D., Kremer, A. E., Syngelaki, A., Noori, M., Williams, D., Marin, J. J. G., Monte, M. J., Nicolaides, K. H., Beuers, U., Oude-Elferink, R., Seed, P. T., Chappell, L. & 3 others, Marschall, H-U., Bunnett, N. W. & Williamson, C., 28 Dec 2015, In : Hepatology.

    Research output: Contribution to journalArticle

  28. The NADPH oxidase Nox4 has anti-atherosclerotic functions

    Schürmann, C., Rezende, F., Kruse, C., Yasar, Y., Löwe, O., Fork, C., Van De Sluis, B., Bremer, R., Weissmann, N., Shah, A. M., Jo, H., Brandes, R. P. & Schröder, K., 21 Dec 2015, In : European Heart Journal. 36, 48, p. 3447-3456 10 p.

    Research output: Contribution to journalArticle

  29. NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

    Murray, T. V. A., Dong, X., Sawyer, G. J., Caldwell, A., Halket, J., Sherwood, R., Quaglia, A., Dew, T., Anilkumar, N., Burr, S., Mistry, R. K., Martin, D., Schröder, K., Brandes, R. P., Hughes, R. D., Shah, A. M. & Brewer, A. C., 1 Dec 2015, In : Free Radical Biology and Medicine. 89, p. 918-930 13 p.

    Research output: Contribution to journalArticle

  30. A Randomized Trial of Progesterone in Women with Recurrent Miscarriages

    Coomarasamy, A., Williams, H., Truchanowicz, E., Seed, P. T., Small, R., Quenby, S., Gupta, P., Dawood, F., Koot, Y. E. M., Bender Atik, R., Bloemenkamp, K. W. M., Brady, R., Briley, A. L., Cavallaro, R., Cheong, Y. C., Chu, J. J., Eapen, A., Ewies, A., Hoek, A., Kaaijk, E. M. & 15 others, Koks, C. A. M., Li, T-C., MacLean, M., Mol, B. W., Moore, J., Ross, J. A., Sharpe, L., Stewart, J., Vaithilingam, N., Farquharson, R. G., Kilby, M. D., Khalaf, Y., Goddijn, M., Regan, L. & Rai, R., 26 Nov 2015, In : New England Journal of Medicine. 373, 22, p. 2141-8 8 p.

    Research output: Contribution to journalArticle

  31. Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial

    Poston, L., Bell, R., Croker, H., Flynn, A. C., Godfrey, K. M., Goff, L., Hayes, L., Khazaezadeh, N., Nelson, S. M., Oteng-Ntim, E., Pasupathy, D., Patel, N., Robson, S. C., Sandall, J., Sanders, T. A. B., Sattar, N., Seed, P. T., Wardle, J., Whitworth, M. K., Briley, A. L. & 1 others, UPBEAT Trial Consortium, 1 Oct 2015, In : The Lancet Diabetes and Endocrinology. 3, 10, p. 767-777 11 p.

    Research output: Contribution to journalArticle

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