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Research Outputs

  1. 2020
  2. Acute heart failure

    Arrigo, M., Jessup, M., Mullens, W., Reza, N., Shah, A. M., Sliwa, K. & Mebazaa, A., 1 Dec 2020, In : Nature Reviews Disease Primers. 6, 1, 16.

    Research output: Contribution to journalReview article

  3. Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders

    Seidlitz, J., Nadig, A., Liu, S., Bethlehem, R. A. I., Vértes, P. E., Morgan, S. E., Váša, F., Romero-Garcia, R., Lalonde, F. M., Clasen, L. S., Blumenthal, J. D., Paquola, C., Bernhardt, B., Wagstyl, K., Polioudakis, D., de la Torre-Ubieta, L., Geschwind, D. H., Han, J. C., Lee, N. R., Murphy, D. G. & 2 others, Bullmore, E. T. & Raznahan, A., 1 Dec 2020, In : Nature Communications. 11, 1, 3358.

    Research output: Contribution to journalArticle

  4. Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

    MRC AIMS consortium, 4 Aug 2020, In : eLife. 9

    Research output: Contribution to journalArticle

  5. The effect of smoking on COVID-19 severity: a systematic review and meta-analysis

    Reddy, R. K., Charles, W. N., Sklavounos, A., Dutt, A., Seed, P. T. & Khajuria, A., 4 Aug 2020, In : Journal of Medical Virology.

    Research output: Contribution to journalArticle

  6. In vivo [U-13C]glucose labeling to assess heart metabolism in murine models of pressure and volume overload

    Schnelle, M., Chong, M., Zoccarato, A., Elkenani, M., Sawyer, G. J., Hasenfuss, G., Ludwig, C. & Shah, A. M., 1 Aug 2020, In : American journal of physiology. Heart and circulatory physiology. 319, 2, p. H422-H431

    Research output: Contribution to journalArticle

  7. Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage

    Maqbool, A., Watt, N. T., Haywood, N., Viswambharan, H., Skromna, A., Makava, N., Visnagri, A., Shawer, H. M., Bridge, K., Muminov, S. K., Griffin, K., Beech, D. J., Wheatcroft, S. B., Porter, K. E., Simmons, K. J., Sukumar, P., Shah, A. M., Cubbon, R. M., Kearney, M. T. & Yuldasheva, N. Y., Jul 2020, In : American Journal of Physiology - Cell Physiology. 318, 1, p. C64-C74

    Research output: Contribution to journalArticle

  8. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In : Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticle

  9. The UK pregnancies better eating and activity trial (UPBEAT); pregnancy outcomes and health behaviours by obesity class

    Peacock, L., Seed, P. T., Dalrymple, K. V., White, S. L., Poston, L. & Flynn, A. C., Jul 2020, In : International Journal of Environmental Research and Public Health. 17, 13, p. 1-17 17 p., 4712.

    Research output: Contribution to journalArticle

  10. Monte Carlo simulation of uncertainty to identify barriers to optimizing blood pressure control

    Zanisi, L., Floyd, C. N., Barrett, J. E., Bunce, C., Frohmaier, C., Shankar, F. & Chowienczyk, P. J., 29 Jun 2020, In : Journal of Hypertension.

    Research output: Contribution to journalArticle

  11. COVID-19 and Autism Research: Perspectives from Around the Globe

    Oakley, B., Tillmann, J., Ruigrok, A. N. V. & Murphy, D., 27 Jun 2020, In : Autism research. 13, 6, p. 844-869 26 p.

    Research output: Contribution to journalComment/debate

  12. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 1 Jun 2020, In : HYPERTENSION IN PREGNANCY. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  13. Publisher Correction: ASPI: a public–private partnership to develop treatments for autism (Nature Reviews Drug Discovery, (2020), 19, 4, (219-220), 10.1038/d41573-020-00012-4)

    Ness, S., Pandina, G., Jagannatha, S., Wathen, K., Bangerter, A., Manyakov, N. V., Hendren, R., Leventhal, B., Murphy, D., Dawson, G., Drevets, W. C. & Manji, H. K., 1 Jun 2020, In : Nature Reviews Drug Discovery. 19, 6, 1 p.

    Research output: Contribution to journalComment/debate

  14. A Clinical Risk Score to Identify Patients with COVID-19 at High Risk of Critical Care Admission or Death: An Observational Cohort Study

    Galloway, J., Norton, S., Barker, R. D., Brookes, A., Carey, I., Clarke, B., Jina, R., Reid, C., Russell, M. D., Sneep, R., Sugarman, L., Williams, S., Yates, M., Teo, J. T., Shah, A. & Cantle, F., 18 May 2020, In : Journal of Infection. 81, 2, p. 282-288 7 p.

    Research output: Contribution to journalArticle

  15. Beyond Bacterial Killing: NADPH oxidase 2 is an immunomodulator

    Cellone Trevelin, S., Shah, A. & Lombardi, G., May 2020, In : Immunology Letters. 221, p. 39-48 10 p.

    Research output: Contribution to journalReview article

  16. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In : Thorax.

    Research output: Contribution to journalArticle

  17. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In : Trials. 21, 1, p. 347

    Research output: Contribution to journalArticle

  18. Effect of Face-Down Positioning vs Support-the-Break Positioning After Macula-Involving Retinal Detachment Repair The PostRD Randomized Clinical Trial

    Casswell, E. J., Yorston, D., Lee, E., Heeren, T. F. C., Harris, N., Zvobgo, T. M., Tarafdar, S., Xing, W., Bourmpaki, E., Bunce, C., Keane, P. & Charteris, D. G., 16 Apr 2020, In : JAMA Ophthalmology.

    Research output: Contribution to journalArticle

  19. Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)

    Kaura, A., Arnold, A. D., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Melikian, N., Lefroy, D. C. & 6 others, Francis, D. P., Shah, A. M., Kharbanda, R., Perera, D., Patel, R. S. & Mayet, J., 7 Apr 2020, In : Journal of the American Heart Association. 9, 7, p. e013684

    Research output: Contribution to journalArticle

  20. Factors influencing the decision-making of carers of children with bilateral cataract in Nepal

    Bell, S. J., Singh, T., Bunce, C., Singh, S. K., Bascaran, C., Gilbert, C. & Foster, A., 6 Apr 2020, In : BMJ Open Ophthalmology. 5, 1, e000422.

    Research output: Contribution to journalArticle

  21. ASPI: a public-private partnership to develop treatments for autism

    Ness, S., Pandina, G., Jagannatha, S., Wathen, K., Bangerter, A., Manyakov, N. V., Hendren, R. L., Leventhal, B. L., Murphy, D., Dawson, G., Drevets, W. C. & Manji, H., 1 Apr 2020, In : Nature Reviews Drug Discovery. 19, 4, p. 219-220 2 p.

    Research output: Contribution to journalComment/debate

  22. A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation

    Yang, J., Moraga, A., Xu, J., Zhao, Y., Luo, P., Lao, K. H., Margariti, A., Zhao, Q., Ding, W., Wang, G., Zhang, M., Zheng, L., Zhang, Z., Hu, Y., Wang, W., Shen, L., Smith, A., Shah, A. M., Wang, Q. & Zeng, L., Apr 2020, In : Stem Cells. 38, 4, p. 556-573 18 p.

    Research output: Contribution to journalArticle

  23. Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

    Martins, D. A., Mazibuko, N., Zelaya, F., Vasilakopoulou, S., Loveridge, J., Oates, A., Maltezos, S., Mehta, M., Wastling, S., Howard, M., McAlonan, G., Murphy, D., Williams, S., Fotopoulou, A., Schuschnig, U. & Paloyelis, Y., 3 Mar 2020, In : Nature Communications. 11, 1, 1160.

    Research output: Contribution to journalArticle

  24. Greater cortical thickness in individuals with ASD

    MRC AIMS consortium, 1 Mar 2020, In : Molecular Psychiatry. 25, 3, p. 507-508 2 p.

    Research output: Contribution to journalComment/debate

  25. Serious bacterial infections and antibiotic prescribing in primary care: cohort study using electronic health records in the UK

    And SafeAB Research Group, 28 Feb 2020, In : BMJ Open. 10, 2, p. e036975 e036975.

    Research output: Contribution to journalArticle

  26. Cytokine mRNA degradation in cardiomyocytes restrains sterile inflammation in pressure overloaded hearts

    Omiya, S., Omori, Y., Taneike, M., Murakawa, T., Ito, J., Tanada, Y., Nishida, K., Yamaguchi, O., Satoh, T., Shah, A. M., Akira, S. & Otsu, K., 25 Feb 2020, In : Circulation. 141, 8, p. 667-677 11 p.

    Research output: Contribution to journalArticle

  27. Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project

    EU-AIMS LEAP group, 22 Feb 2020, In : Molecular Autism. 11, 1, p. 17

    Research output: Contribution to journalArticle

  28. Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness

    Ching, C. R. K., Gutman, B. A., Sun, D., Villalon Reina, J., Ragothaman, A., Isaev, D., Zavaliangos-petropulu, A., Lin, A., Jonas, R. K., Kushan, L., Pacheco-hansen, L., Vajdi, A., Forsyth, J. K., Jalbrzikowski, M., Bakker, G., Van Amelsvoort, T., Antshel, K. M., Fremont, W., Kates, W. R., Campbell, L. E. & 35 others, Mccabe, K. L., Craig, M. C., Daly, E., Gudbrandsen, M., Murphy, C. M., Murphy, D. G., Murphy, K. C., Fiksinski, A., Koops, S., Vorstman, J., Crowley, T. B., Emanuel, B. S., Gur, R. E., Mcdonald-mcginn, D. M., Roalf, D. R., Ruparel, K., Schmitt, J. E., Zackai, E. H., Durdle, C. A., Goodrich-hunsaker, N. J., Simon, T. J., Bassett, A. S., Butcher, N. J., Chow, E. W. C., Vila-rodriguez, F., Cunningham, A., Doherty, J., Linden, D. E., Moss, H., Owen, M. J., Van Den Bree, M., Crossley, N. A., Repetto, G. M., Thompson, P. M. & Bearden, C. E., 12 Feb 2020, In : American Journal of Psychiatry.

    Research output: Contribution to journalArticle

  29. Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion

    Cleynen, I., Engchuan, W., Hestand, M. S., Heung, T., Holleman, A. M., Johnston, H. R., Monfeuga, T., McDonald-McGinn, D. M., Gur, R. E., Morrow, B. E., Swillen, A., Vorstman, J. A. S., Bearden, C. E., Chow, E. W. C., van den Bree, M., Emanuel, B. S., Vermeesch, J. R., Warren, S. T., Owen, M. J., Chopra, P. & 75 others, Cutler, D. J., Duncan, R., Kotlar, A. V., Mulle, J. G., Voss, A. J., Zwick, M. E., Diacou, A., Golden, A., Guo, T., Lin, J-R., Wang, T., Zhang, Z., Zhao, Y., Marshall, C., Merico, D., Jin, A., Lilley, B., Salmons, H. I., Tran, O., Holmans, P., Pardinas, A., Walters, J. T. R., Demaerel, W., Boot, E., Butcher, N. J., Costain, G. A., Daly, E. M., Gudbrandsen, M., Murphy, C. M., Murphy, D. G., Buzzanca, A., Di Fabio, F., Digilio, M. C., Pontillo, M., Marino, B., Vicari, S., Coleman, K., Cubells, J. F., Ousley, O. Y., Carmel, M., Gothelf, D., Mekori-Domachevsky, E., Michaelovsky, E., Weinberger, R., Weizman, A., Kushan, L., Jalbrzikowski, M., Armando, M., Eliez, S., Sandini, C., Schneider, M., Sloan Béna, F., M. Antshel, K., Fremont, W., R. Kates, W., Belzeaux, R., Busa, T., Philip, N., Campbell, L. E., McCabe, K. L., R. Hooper, S., Schoch, K., Shashi, V., J. Simon, T., Tassone, F., Arango, C., Fraguas, D., García-Miñaúr, S., Morey-Canyelles, J., Rosell, J., H. Suñer, D., Raventos-Simic, J., P. Epstein, M., M. Williams, N. & S. Bassett, A., 3 Feb 2020, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  30. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

    Delitsikou, V., Jarad, G., Rajaram, R. D., Ino, F., Rutkowski, J. M., Chen, C. D., Santos, C. X. C., Scherer, P. E., Abraham, C. R., Shah, A. M., Feraille, E., Miner, J. H. & de Seigneux, S., 1 Feb 2020, In : Faseb Journal. 34, 2, p. 2087-2104 18 p.

    Research output: Contribution to journalArticle

  31. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In : Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  32. NADPH oxidase 2 mediates myocardial oxygen wasting in obesity

    Hafstad, A. D., Hansen, S. S., Lund, J., Santos, C. X. C., Boardman, N. T., Shah, A. M. & Aasum, E., Feb 2020, In : Antioxidants. 9, 2, 171.

    Research output: Contribution to journalArticle

  33. Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects

    Zhao, Y., Diacou, A., Johnston, H. R., Musfee, F. I., McDonald-McGinn, D. M., McGinn, D., Crowley, T. B., Repetto, G. M., Swillen, A., Breckpot, J., Vermeesch, J. R., Kates, W. R., Digilio, M. C., Unolt, M., Marino, B., Pontillo, M., Armando, M., Di Fabio, F., Vicari, S., van den Bree, M. & 30 others, Moss, H., Owen, M. J., Murphy, K. C., Murphy, C. M., Murphy, D., Schoch, K., Shashi, V., Tassone, F., Simon, T. J., Shprintzen, R. J., Campbell, L., Philip, N., Heine-Suñer, D., García-Miñaúr, S., Fernández, L., Antonarakis, S. E., Biondi, M., Boot, E., Breetvelt, E., Busa, T., Butcher, N., Buzzanca, A., Carmel, M., Cleynen, I., Cutler, D., Dallapiccola, B., de la Fuente Sanches, M. A., Epstein, M. P., Evers, R. & Lattanzi, G., 2 Jan 2020, In : American Journal of Human Genetics. 106, 1, p. 26-40 15 p.

    Research output: Contribution to journalArticle

  34. Celastrol Alleviates Aortic Valve Calcification Via Inhibition of NADPH Oxidase 2 in Valvular Interstitial Cells

    Liu, H., Wang, L., Pan, Y., Wang, X., Ding, Y., Zhou, C., Shah, A. M., Zhao, G. & Zhang, M., 1 Jan 2020, In : JACC: Basic to Translational Science. 5, 1, p. 35-49 15 p.

    Research output: Contribution to journalArticle

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