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Research Outputs

  1. 2020
  2. Acute heart failure

    Arrigo, M., Jessup, M., Mullens, W., Reza, N., Shah, A. M., Sliwa, K. & Mebazaa, A., 1 Dec 2020, In : Nature Reviews Disease Primers. 6, 1, 16.

    Research output: Contribution to journalReview article

  3. Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders

    Seidlitz, J., Nadig, A., Liu, S., Bethlehem, R. A. I., Vértes, P. E., Morgan, S. E., Váša, F., Romero-Garcia, R., Lalonde, F. M., Clasen, L. S., Blumenthal, J. D., Paquola, C., Bernhardt, B., Wagstyl, K., Polioudakis, D., de la Torre-Ubieta, L., Geschwind, D. H., Han, J. C., Lee, N. R., Murphy, D. G. & 2 others, Bullmore, E. T. & Raznahan, A., 1 Dec 2020, In : Nature Communications. 11, 1, 3358.

    Research output: Contribution to journalArticle

  4. Open letter from UK based academic scientists to the secretaries of state for digital, culture, media and sport and for health and social care regarding the need for independent funding for the prevention and treatment of gambling harms

    Wardle, H., Banks, J., Bebbington, P., Blank, L., Bowden Jones Obe, H., Bramley, S., Bunn, C., Casey, E., Cassidy, R., Chamberlain, S. R., Close, J., Critchlow, N., Dobbie, F., Downs, C., Dymond, S., Fino, E., Goyder, E., Gray, C., Griffiths, M., Grindrod, P. & 28 others, Hogan, L., Hoon, A., Hunt, K., James, R., John, B., Manthorpe, J., McCambridge, J., McDaid, D., McKee, M., McManus, S., Moss, A., Norrie, C., Nutt, D. J., Orford, J., Pryce, R., Purves, R., Reith, G., Roberts, A., Roberts, E., Roderique-Davies, G., Rogers, J., Rogers, R. D., Sharman, S., Strang, J., Tunney, R., Turner, J., West, R. & Zendle, D., 1 Jul 2020, In : BMJ (Clinical research ed.). 370, p. m2613

    Research output: Contribution to journalArticle

  5. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In : Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticle

  6. The UK pregnancies better eating and activity trial (UPBEAT); pregnancy outcomes and health behaviours by obesity class

    Peacock, L., Seed, P. T., Dalrymple, K. V., White, S. L., Poston, L. & Flynn, A. C., Jul 2020, In : International Journal of Environmental Research and Public Health. 17, 13, p. 1-17 17 p., 4712.

    Research output: Contribution to journalArticle

  7. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 1 Jun 2020, In : HYPERTENSION IN PREGNANCY. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  8. Publisher Correction: ASPI: a public–private partnership to develop treatments for autism (Nature Reviews Drug Discovery, (2020), 19, 4, (219-220), 10.1038/d41573-020-00012-4)

    Ness, S., Pandina, G., Jagannatha, S., Wathen, K., Bangerter, A., Manyakov, N. V., Hendren, R., Leventhal, B., Murphy, D., Dawson, G., Drevets, W. C. & Manji, H. K., 1 Jun 2020, In : Nature Reviews Drug Discovery. 19, 6, 1 p.

    Research output: Contribution to journalComment/debate

  9. A Clinical Risk Score to Identify Patients with COVID-19 at High Risk of Critical Care Admission or Death: An Observational Cohort Study

    Galloway, J., Norton, S., Barker, R. D., Brookes, A., Carey, I., Clarke, B., Jina, R., Reid, C., Russell, M. D., Sneep, R., Sugarman, L., Williams, S., Yates, M., Teo, J. T., Shah, A. & Cantle, F., 18 May 2020, In : Journal of Infection. 81, 2, p. 282-288 7 p.

    Research output: Contribution to journalArticle

  10. A study protocol to assess the feasibility of conducting an evaluation trial of the ADVANCE integrated intervention to address both substance use and intimate partner abuse perpetration to men in substance use treatment

    Gilchrist, G., Landau, S., Radcliffe, P., McMurran, M., Feder, G., Easton, C., Parrott, S., Kirkpatrick, S., Henderson, J., Potts, L., Stephens-Lewis, D., Johnson, A., Love, B., Halliwell, G., Dheensa, S., Berbary, C., Li, J., Strang, J. & Gilchrist, E., 11 May 2020, In : Pilot and Feasibility Studies. 6, 1, 62.

    Research output: Contribution to journalArticle

  11. Editorial: Challenges to Opioid Use Disorders During COVID-19

    Sun, Y., Bao, Y., Kosten, T., Strang, J., Shi, J. & Lu, L., 1 May 2020, In : American Journal on Addictions. 29, 3, p. 174-175 2 p.

    Research output: Contribution to journalEditorial

  12. Beyond Bacterial Killing: NADPH oxidase 2 is an immunomodulator

    Cellone Trevelin, S., Shah, A. & Lombardi, G., May 2020, In : Immunology Letters. 221, p. 39-48 10 p.

    Research output: Contribution to journalReview article

  13. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In : Thorax.

    Research output: Contribution to journalArticle

  14. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In : Trials. 21, 1, p. 347

    Research output: Contribution to journalArticle

  15. Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)

    Kaura, A., Arnold, A. D., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Melikian, N., Lefroy, D. C. & 6 others, Francis, D. P., Shah, A. M., Kharbanda, R., Perera, D., Patel, R. S. & Mayet, J., 7 Apr 2020, In : Journal of the American Heart Association. 9, 7, p. e013684

    Research output: Contribution to journalArticle

  16. ASPI: a public-private partnership to develop treatments for autism

    Ness, S., Pandina, G., Jagannatha, S., Wathen, K., Bangerter, A., Manyakov, N. V., Hendren, R. L., Leventhal, B. L., Murphy, D., Dawson, G., Drevets, W. C. & Manji, H., 1 Apr 2020, In : Nature Reviews Drug Discovery. 19, 4, p. 219-220 2 p.

    Research output: Contribution to journalComment/debate

  17. A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation

    Yang, J., Moraga, A., Xu, J., Zhao, Y., Luo, P., Lao, K. H., Margariti, A., Zhao, Q., Ding, W., Wang, G., Zhang, M., Zheng, L., Zhang, Z., Hu, Y., Wang, W., Shen, L., Smith, A., Shah, A. M., Wang, Q. & Zeng, L., Apr 2020, In : Stem Cells. 38, 4, p. 556-573 18 p.

    Research output: Contribution to journalArticle

  18. Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

    Martins, D. A., Mazibuko, N., Zelaya, F., Vasilakopoulou, S., Loveridge, J., Oates, A., Maltezos, S., Mehta, M., Wastling, S., Howard, M., McAlonan, G., Murphy, D., Williams, S., Fotopoulou, A., Schuschnig, U. & Paloyelis, Y., 3 Mar 2020, In : Nature Communications. 11, 1, 1160.

    Research output: Contribution to journalArticle

  19. Greater cortical thickness in individuals with ASD

    MRC AIMS consortium, 1 Mar 2020, In : Molecular Psychiatry. 25, 3, p. 507-508 2 p.

    Research output: Contribution to journalComment/debate

  20. Cytokine mRNA degradation in cardiomyocytes restrains sterile inflammation in pressure overloaded hearts

    Omiya, S., Omori, Y., Taneike, M., Murakawa, T., Ito, J., Tanada, Y., Nishida, K., Yamaguchi, O., Satoh, T., Shah, A. M., Akira, S. & Otsu, K., 25 Feb 2020, In : Circulation. 141, 8, p. 667-677 11 p.

    Research output: Contribution to journalArticle

  21. Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project

    EU-AIMS LEAP group, 22 Feb 2020, In : Molecular Autism. 11, 1, p. 17

    Research output: Contribution to journalArticle

  22. Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness

    Ching, C. R. K., Gutman, B. A., Sun, D., Villalon Reina, J., Ragothaman, A., Isaev, D., Zavaliangos-petropulu, A., Lin, A., Jonas, R. K., Kushan, L., Pacheco-hansen, L., Vajdi, A., Forsyth, J. K., Jalbrzikowski, M., Bakker, G., Van Amelsvoort, T., Antshel, K. M., Fremont, W., Kates, W. R., Campbell, L. E. & 35 others, Mccabe, K. L., Craig, M. C., Daly, E., Gudbrandsen, M., Murphy, C. M., Murphy, D. G., Murphy, K. C., Fiksinski, A., Koops, S., Vorstman, J., Crowley, T. B., Emanuel, B. S., Gur, R. E., Mcdonald-mcginn, D. M., Roalf, D. R., Ruparel, K., Schmitt, J. E., Zackai, E. H., Durdle, C. A., Goodrich-hunsaker, N. J., Simon, T. J., Bassett, A. S., Butcher, N. J., Chow, E. W. C., Vila-rodriguez, F., Cunningham, A., Doherty, J., Linden, D. E., Moss, H., Owen, M. J., Van Den Bree, M., Crossley, N. A., Repetto, G. M., Thompson, P. M. & Bearden, C. E., 12 Feb 2020, In : American Journal of Psychiatry.

    Research output: Contribution to journalArticle

  23. Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion

    Cleynen, I., Engchuan, W., Hestand, M. S., Heung, T., Holleman, A. M., Johnston, H. R., Monfeuga, T., McDonald-McGinn, D. M., Gur, R. E., Morrow, B. E., Swillen, A., Vorstman, J. A. S., Bearden, C. E., Chow, E. W. C., van den Bree, M., Emanuel, B. S., Vermeesch, J. R., Warren, S. T., Owen, M. J., Chopra, P. & 75 others, Cutler, D. J., Duncan, R., Kotlar, A. V., Mulle, J. G., Voss, A. J., Zwick, M. E., Diacou, A., Golden, A., Guo, T., Lin, J-R., Wang, T., Zhang, Z., Zhao, Y., Marshall, C., Merico, D., Jin, A., Lilley, B., Salmons, H. I., Tran, O., Holmans, P., Pardinas, A., Walters, J. T. R., Demaerel, W., Boot, E., Butcher, N. J., Costain, G. A., Daly, E. M., Gudbrandsen, M., Murphy, C. M., Murphy, D. G., Buzzanca, A., Di Fabio, F., Digilio, M. C., Pontillo, M., Marino, B., Vicari, S., Coleman, K., Cubells, J. F., Ousley, O. Y., Carmel, M., Gothelf, D., Mekori-Domachevsky, E., Michaelovsky, E., Weinberger, R., Weizman, A., Kushan, L., Jalbrzikowski, M., Armando, M., Eliez, S., Sandini, C., Schneider, M., Sloan Béna, F., M. Antshel, K., Fremont, W., R. Kates, W., Belzeaux, R., Busa, T., Philip, N., Campbell, L. E., McCabe, K. L., R. Hooper, S., Schoch, K., Shashi, V., J. Simon, T., Tassone, F., Arango, C., Fraguas, D., García-Miñaúr, S., Morey-Canyelles, J., Rosell, J., H. Suñer, D., Raventos-Simic, J., P. Epstein, M., M. Williams, N. & S. Bassett, A., 3 Feb 2020, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  24. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

    Delitsikou, V., Jarad, G., Rajaram, R. D., Ino, F., Rutkowski, J. M., Chen, C. D., Santos, C. X. C., Scherer, P. E., Abraham, C. R., Shah, A. M., Feraille, E., Miner, J. H. & de Seigneux, S., 1 Feb 2020, In : Faseb Journal. 34, 2, p. 2087-2104 18 p.

    Research output: Contribution to journalArticle

  25. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In : Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  26. Untreated help seekers in addiction services: an opportunity to reach under-served groups in research

    Boniface, S. & Strang, J., 1 Feb 2020, In : The lancet. Psychiatry. 7, 2, p. 116-117 2 p.

    Research output: Contribution to journalComment/debate

  27. NADPH oxidase 2 mediates myocardial oxygen wasting in obesity

    Hafstad, A. D., Hansen, S. S., Lund, J., Santos, C. X. C., Boardman, N. T., Shah, A. M. & Aasum, E., Feb 2020, In : Antioxidants. 9, 2, 171.

    Research output: Contribution to journalArticle

  28. Adolescent alcohol use disorders presenting through emergency departments: Development and randomised controlled trial of age-specific alcohol screening and brief interventions (SIPS Junior Research Programme)

    Deluca, P., Coulton, S., Alam, M. F., Boniface, S., Donoghue, K., Gilvarry, E., Kaner, E., Lynch, E., Maconochie, I., McArdle, P., McGovern, R., Newbury-Birch, D., Patton, R., Pellatt-Higgins, T., Phillips, C., Phillips, T., Pockett, R., Russell, I., Strang, J. & Drummond, C., 31 Jan 2020, In : Programme Grants for Applied Research . 8, 2, 144 p.

    Research output: Contribution to journalArticle

  29. Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects

    Zhao, Y., Diacou, A., Johnston, H. R., Musfee, F. I., McDonald-McGinn, D. M., McGinn, D., Crowley, T. B., Repetto, G. M., Swillen, A., Breckpot, J., Vermeesch, J. R., Kates, W. R., Digilio, M. C., Unolt, M., Marino, B., Pontillo, M., Armando, M., Di Fabio, F., Vicari, S., van den Bree, M. & 30 others, Moss, H., Owen, M. J., Murphy, K. C., Murphy, C. M., Murphy, D., Schoch, K., Shashi, V., Tassone, F., Simon, T. J., Shprintzen, R. J., Campbell, L., Philip, N., Heine-Suñer, D., García-Miñaúr, S., Fernández, L., Antonarakis, S. E., Biondi, M., Boot, E., Breetvelt, E., Busa, T., Butcher, N., Buzzanca, A., Carmel, M., Cleynen, I., Cutler, D., Dallapiccola, B., de la Fuente Sanches, M. A., Epstein, M. P., Evers, R. & Lattanzi, G., 2 Jan 2020, In : American Journal of Human Genetics. 106, 1, p. 26-40 15 p.

    Research output: Contribution to journalArticle

  30. Celastrol Alleviates Aortic Valve Calcification Via Inhibition of NADPH Oxidase 2 in Valvular Interstitial Cells

    Liu, H., Wang, L., Pan, Y., Wang, X., Ding, Y., Zhou, C., Shah, A. M., Zhao, G. & Zhang, M., 1 Jan 2020, In : JACC: Basic to Translational Science. 5, 1, p. 35-49 15 p.

    Research output: Contribution to journalArticle

  31. Medication treatment of opioid use disorder

    Bell, J. & Strang, J. S., 1 Jan 2020, In : Biological psychiatry. 87, 1, p. 82-88

    Research output: Contribution to journalReview article

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