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Research Outputs

  1. 2020
  2. Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders

    Seidlitz, J., Nadig, A., Liu, S., Bethlehem, R. A. I., Vértes, P. E., Morgan, S. E., Váša, F., Romero-Garcia, R., Lalonde, F. M., Clasen, L. S., Blumenthal, J. D., Paquola, C., Bernhardt, B., Wagstyl, K., Polioudakis, D., de la Torre-Ubieta, L., Geschwind, D. H., Han, J. C., Lee, N. R., Murphy, D. G. & 2 others, Bullmore, E. T. & Raznahan, A., 1 Dec 2020, In : Nature Communications. 11, 1, 3358.

    Research output: Contribution to journalArticle

  3. An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene

    Roubroeks, J. A. Y., Smith, A. R., Smith, R. G., Pishva, E., Ibrahim, Z., Sattlecker, M., Hannon, E. J., Kłoszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Wahlund, L. O., Aarsland, D., Proitsi, P., Hodges, A., Lovestone, S., Newhouse, S. J., Dobson, R. J. B., Mill, J. & 2 others, van den Hove, D. L. A. & Lunnon, K., Nov 2020, In : Neurobiology of Aging. 95, p. 26-45 20 p.

    Research output: Contribution to journalArticle

  4. The effect of smoking on COVID-19 severity: a systematic review and meta-analysis

    Reddy, R. K., Charles, W. N., Sklavounos, A., Dutt, A., Seed, P. T. & Khajuria, A., 4 Aug 2020, In : Journal of Medical Virology.

    Research output: Contribution to journalArticle

  5. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In : Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticle

  6. The UK pregnancies better eating and activity trial (UPBEAT); pregnancy outcomes and health behaviours by obesity class

    Peacock, L., Seed, P. T., Dalrymple, K. V., White, S. L., Poston, L. & Flynn, A. C., Jul 2020, In : International Journal of Environmental Research and Public Health. 17, 13, p. 1-17 17 p., 4712.

    Research output: Contribution to journalArticle

  7. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 1 Jun 2020, In : HYPERTENSION IN PREGNANCY. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  8. Publisher Correction: ASPI: a public–private partnership to develop treatments for autism (Nature Reviews Drug Discovery, (2020), 19, 4, (219-220), 10.1038/d41573-020-00012-4)

    Ness, S., Pandina, G., Jagannatha, S., Wathen, K., Bangerter, A., Manyakov, N. V., Hendren, R., Leventhal, B., Murphy, D., Dawson, G., Drevets, W. C. & Manji, H. K., 1 Jun 2020, In : Nature Reviews Drug Discovery. 19, 6, 1 p.

    Research output: Contribution to journalComment/debate

  9. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In : Thorax.

    Research output: Contribution to journalArticle

  10. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In : Trials. 21, 1, p. 347

    Research output: Contribution to journalArticle

  11. ASPI: a public-private partnership to develop treatments for autism

    Ness, S., Pandina, G., Jagannatha, S., Wathen, K., Bangerter, A., Manyakov, N. V., Hendren, R. L., Leventhal, B. L., Murphy, D., Dawson, G., Drevets, W. C. & Manji, H., 1 Apr 2020, In : Nature Reviews Drug Discovery. 19, 4, p. 219-220 2 p.

    Research output: Contribution to journalComment/debate

  12. Dysregulated Fc gamma receptor–mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis

    AddNeuroMed consortium and the Alzheimer's Disease Neuroimaging Initiative, Apr 2020, In : Neurobiology of Aging. 88, p. 24-32 9 p.

    Research output: Contribution to journalArticle

  13. Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

    Martins, D. A., Mazibuko, N., Zelaya, F., Vasilakopoulou, S., Loveridge, J., Oates, A., Maltezos, S., Mehta, M., Wastling, S., Howard, M., McAlonan, G., Murphy, D., Williams, S., Fotopoulou, A., Schuschnig, U. & Paloyelis, Y., 3 Mar 2020, In : Nature Communications. 11, 1, 1160.

    Research output: Contribution to journalArticle

  14. Greater cortical thickness in individuals with ASD

    MRC AIMS consortium, 1 Mar 2020, In : Molecular Psychiatry. 25, 3, p. 507-508 2 p.

    Research output: Contribution to journalComment/debate

  15. Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project

    EU-AIMS LEAP group, 22 Feb 2020, In : Molecular Autism. 11, 1, p. 17

    Research output: Contribution to journalArticle

  16. Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness

    Ching, C. R. K., Gutman, B. A., Sun, D., Villalon Reina, J., Ragothaman, A., Isaev, D., Zavaliangos-petropulu, A., Lin, A., Jonas, R. K., Kushan, L., Pacheco-hansen, L., Vajdi, A., Forsyth, J. K., Jalbrzikowski, M., Bakker, G., Van Amelsvoort, T., Antshel, K. M., Fremont, W., Kates, W. R., Campbell, L. E. & 35 others, Mccabe, K. L., Craig, M. C., Daly, E., Gudbrandsen, M., Murphy, C. M., Murphy, D. G., Murphy, K. C., Fiksinski, A., Koops, S., Vorstman, J., Crowley, T. B., Emanuel, B. S., Gur, R. E., Mcdonald-mcginn, D. M., Roalf, D. R., Ruparel, K., Schmitt, J. E., Zackai, E. H., Durdle, C. A., Goodrich-hunsaker, N. J., Simon, T. J., Bassett, A. S., Butcher, N. J., Chow, E. W. C., Vila-rodriguez, F., Cunningham, A., Doherty, J., Linden, D. E., Moss, H., Owen, M. J., Van Den Bree, M., Crossley, N. A., Repetto, G. M., Thompson, P. M. & Bearden, C. E., 12 Feb 2020, In : American Journal of Psychiatry.

    Research output: Contribution to journalArticle

  17. Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion

    Cleynen, I., Engchuan, W., Hestand, M. S., Heung, T., Holleman, A. M., Johnston, H. R., Monfeuga, T., McDonald-McGinn, D. M., Gur, R. E., Morrow, B. E., Swillen, A., Vorstman, J. A. S., Bearden, C. E., Chow, E. W. C., van den Bree, M., Emanuel, B. S., Vermeesch, J. R., Warren, S. T., Owen, M. J., Chopra, P. & 75 others, Cutler, D. J., Duncan, R., Kotlar, A. V., Mulle, J. G., Voss, A. J., Zwick, M. E., Diacou, A., Golden, A., Guo, T., Lin, J-R., Wang, T., Zhang, Z., Zhao, Y., Marshall, C., Merico, D., Jin, A., Lilley, B., Salmons, H. I., Tran, O., Holmans, P., Pardinas, A., Walters, J. T. R., Demaerel, W., Boot, E., Butcher, N. J., Costain, G. A., Daly, E. M., Gudbrandsen, M., Murphy, C. M., Murphy, D. G., Buzzanca, A., Di Fabio, F., Digilio, M. C., Pontillo, M., Marino, B., Vicari, S., Coleman, K., Cubells, J. F., Ousley, O. Y., Carmel, M., Gothelf, D., Mekori-Domachevsky, E., Michaelovsky, E., Weinberger, R., Weizman, A., Kushan, L., Jalbrzikowski, M., Armando, M., Eliez, S., Sandini, C., Schneider, M., Sloan Béna, F., M. Antshel, K., Fremont, W., R. Kates, W., Belzeaux, R., Busa, T., Philip, N., Campbell, L. E., McCabe, K. L., R. Hooper, S., Schoch, K., Shashi, V., J. Simon, T., Tassone, F., Arango, C., Fraguas, D., García-Miñaúr, S., Morey-Canyelles, J., Rosell, J., H. Suñer, D., Raventos-Simic, J., P. Epstein, M., M. Williams, N. & S. Bassett, A., 3 Feb 2020, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  18. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In : Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  19. Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects

    Zhao, Y., Diacou, A., Johnston, H. R., Musfee, F. I., McDonald-McGinn, D. M., McGinn, D., Crowley, T. B., Repetto, G. M., Swillen, A., Breckpot, J., Vermeesch, J. R., Kates, W. R., Digilio, M. C., Unolt, M., Marino, B., Pontillo, M., Armando, M., Di Fabio, F., Vicari, S., van den Bree, M. & 30 others, Moss, H., Owen, M. J., Murphy, K. C., Murphy, C. M., Murphy, D., Schoch, K., Shashi, V., Tassone, F., Simon, T. J., Shprintzen, R. J., Campbell, L., Philip, N., Heine-Suñer, D., García-Miñaúr, S., Fernández, L., Antonarakis, S. E., Biondi, M., Boot, E., Breetvelt, E., Busa, T., Butcher, N., Buzzanca, A., Carmel, M., Cleynen, I., Cutler, D., Dallapiccola, B., de la Fuente Sanches, M. A., Epstein, M. P., Evers, R. & Lattanzi, G., 2 Jan 2020, In : American Journal of Human Genetics. 106, 1, p. 26-40 15 p.

    Research output: Contribution to journalArticle

  20. Validation of plasma proteomic biomarkers relating to brain amyloid burden in the EMIF-Alzheimer's disease multimodal biomarker discovery cohort

    Westwood, S., Baird, A. L., Anand, S. N., Nevado-Holgado, A. J., Kormilitzin, A., Shi, L., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I., Vos, S. J. B., Baker, S., Buckley, N. J., Ten Kate, M., Scheltens, P., Teunissen, C. E., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S. & 30 others, De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lléo, A., Sala, I., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Morgan, B. P., Streffer, J., Visser, P. J. & Lovestone, S., 1 Jan 2020, In : Journal of Alzheimer's Disease. 74, 1, p. 213-225 13 p.

    Research output: Contribution to journalArticle

  21. Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: A multi-national multi-database case-control study

    Newby, D., Prieto-Alhambra, D., Duarte-Salles, T., Ansell, D., Pedersen, L., Van Der Lei, J., Mosseveld, M., Rijnbeek, P., James, G., Alexander, M., Egger, P., Podhorna, J., Stewart, R., Perera, G., Avillach, P., Grosdidier, S., Lovestone, S. & Nevado-Holgado, A. J., 2020, In : Alzheimer's Research and Therapy. 12, 1, 38.

    Research output: Contribution to journalArticle

  22. 2019
  23. Lifestyle information and commercial weight management groups to support maternal postnatal weight management and positive lifestyle behaviour: the SWAN feasibility randomised controlled trial

    Bick, D., Taylor, C., Bhavnani, V., Healey, A., Seed, P., Roberts, S., Zasada, M., Avery, A., Craig, V., Khazaezadah, N., McMullen, S., O'Connor, S., Oki, B., Oteng Ntim, E., Poston, L. & Ussher, M., 5 Dec 2019, In : BJOG. 27 p.

    Research output: Contribution to journalArticle

  24. Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets

    Postema, M. C., van Rooij, D., Anagnostou, E., Arango, C., Auzias, G., Behrmann, M., Filho, G. B., Calderoni, S., Calvo, R., Daly, E., Deruelle, C., Di Martino, A., Dinstein, I., Duran, F. L. S., Durston, S., Ecker, C., Ehrlich, S., Fair, D., Fedor, J., Feng, X. & 38 others, Fitzgerald, J., Floris, D. L., Freitag, C. M., Gallagher, L., Glahn, D. C., Gori, I., Haar, S., Hoekstra, L., Jahanshad, N., Jalbrzikowski, M., Janssen, J., King, J. A., Kong, X. Z., Lazaro, L., Lerch, J. P., Luna, B., Martinho, M. M., McGrath, J., Medland, S. E., Muratori, F., Murphy, C. M., Murphy, D. G. M., O'Hearn, K., Oranje, B., Parellada, M., Puig, O., Retico, A., Rosa, P., Rubia, K., Shook, D., Taylor, M. J., Tosetti, M., Wallace, G. L., Zhou, F., Thompson, P. M., Fisher, S. E., Buitelaar, J. K. & Francks, C., 1 Dec 2019, In : Nature Communications. 10, 1, 4958.

    Research output: Contribution to journalArticle

  25. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

    Borges Manna, L., Ovadia, C., Lövgren-Sandblom, A., Chambers, J., Begum, S., Seed, P., Walker, I., Chappell, L. C., Marschall, H-U. & Williamson, C., 1 Dec 2019, In : BJOG. 126, 13, p. 1633-1640 8 p.

    Research output: Contribution to journalArticle

  26. Pattern of Altered Plasma Elemental Phosphorus, Calcium, Zinc, and Iron in Alzheimer's Disease

    for the AddNeuroMed consortium, 1 Dec 2019, In : Scientific Reports. 9, 1, 3147.

    Research output: Contribution to journalArticle

  27. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

    Alzheimer's Disease Neuroimaging Initiative, 1 Nov 2019, In : The Lancet Neurology. 18, 11, p. 1034-1044 11 p.

    Research output: Contribution to journalArticle

  28. Pregnancy-related Acute Kidney Injury in pre-eclampsia: risk factors and renal outcomes

    Conti-Ramsden, F. I., Nathan, H. L., De Greeff, A., Hall, D. R., Seed, P. T., Chappell, L. C., Shennan, A. H. & Bramham, K., Nov 2019, In : Hypertension. 74, 5, p. 1144–1151 8 p.

    Research output: Contribution to journalArticle

  29. Father-infant interactions and infant regional brain volumes: a cross-sectional MRI study

    Sethna, V., Pote, I., Wang, S., Gudbrandsen, C. M., Lee, C., Perry, E. L., P H Adams, K., Watson, C., Kangas, J., Murphy, D. G., Daly, E., Stoencheva, V. V., Kuklisova-Murgasova, M., Williams, S. C. R., Craig, M. C. & McAlonan, G. M., 16 Oct 2019, In : Developmental Cognitive Neuroscience.

    Research output: Contribution to journalArticle

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