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Research Outputs

  1. 2018
  2. Does progesterone prophylaxis to prevent preterm labour improve outcome? A randomised double-blind placebo-controlled trial (OPPTIMUM)

    Norman, J. E., Marlow, N., Messow, C. M., Shennan, A., Bennett, P. R., Thornton, S., Robson, S. C., McConnachie, A., Petrou, S., Sebire, N. J., Lavender, T., Whyte, S. & Norrie, J., 1 Jun 2018, In : Health Technology Assessment. 22, 35, p. 1-304 304 p.

    Research output: Contribution to journalArticle

  3. Interpregnancy weight change and adverse pregnancy outcomes: A systematic review and meta-analysis

    Oteng-Ntim, E., Mononen, S., Sawicki, O., Seed, P. T., Bick, D. & Poston, L., Jun 2018, In : BMJ open. 8, 6, 14 p., e018778.

    Research output: Contribution to journalReview article

  4. Prediction and prevention of preterm birth: a quagmire of evidence

    Shennan, A. H., 1 May 2018, In : Ultrasound in Obstetrics and Gynecology. 51, 5, p. 569-570 2 p.

    Research output: Contribution to journalComment/debate

  5. Evaluation of a novel vital sign device to reduce maternal mortality and morbidity in low-resource settings: a mixed method feasibility study for the CRADLE-3 trial

    Vousden, N., Lawley, E., Nathan, H. L., Seed, P. T., Brown, A., Muchengwa, T., Charantimath, U., Bellad, M., Gidiri, M. F., Goudar, S., Chappell, L. C., Sandall, J., Shennan, A. H. & CRADLE Trial Collaborative Group, 27 Apr 2018, In : BMC Pregnancy and Childbirth. 18, 1, 115.

    Research output: Contribution to journalArticle

  6. Quantitative fibronectin to help decision-making in women with symptoms of preterm labour (QUIDS) part 1: Individual participant data meta-analysis and health economic analysis

    Stock, S. J., Wotherspoon, L. M., Boyd, K. A., Morris, R. K., Dorling, J., Jackson, L., Chandiramani, M., David, A. L., Khalil, A., Shennan, A., Hodgetts Morton, V., Lavender, T., Khan, K., Harper-Clarke, S., Mol, B. W., Riley, R. D., Norrie, J. & Norman, J. E., 1 Apr 2018, In : BMJ Open. 8, 4, e020796.

    Research output: Contribution to journalArticle

  7. Study protocol: Quantitative fibronectin to help decision-making in women with symptoms of preterm labour (QUIDS) part 2, UK Prospective Cohort Study

    Stock, S. J., Wotherspoon, L. M., Boyd, K. A., Morris, R. K., Dorling, J., Jackson, L., Chandiramani, M., David, A. L., Khalil, A., Shennan, A., Hodgetts Morton, V., Lavender, T., Khan, K., Harper-Clarke, S., Mol, B., Riley, R. D., Norrie, J. & Norman, J., 1 Apr 2018, In : BMJ Open. 8, 4, e020795.

    Research output: Contribution to journalArticle

  8. Placental Growth Factor informed management of suspected pre-eclampsia or fetal growth restriction: The MAPPLE cohort study

    Sharp, A., Chappell, L. C., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., Hillerer, K. M., Fischer, T., Seed, P. T., Turner, M., Shennan, A. H. & Alfirevic, Z., 26 Mar 2018, In : Pregnancy Hypertension. 18 p.

    Research output: Contribution to journalArticle

  9. Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

    Smith, R. G., Hannon, E., De Jager, P. L., Chibnik, L., Lott, S. J., Condliffe, D., Smith, A. R., Haroutunian, V., Troakes, C., Al-Sarraj, S., Bennett, D. A., Powell, J., Lovestone, S., Schalkwyk, L., Mill, J. & Lunnon, K., 15 Mar 2018, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  10. A universal standard for the validation of blood pressure measuring devices: Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Collaboration Statement

    Stergiou, G. S., Alpert, B., Mieke, S., Asmar, R., Atkins, N., Eckert, S., Frick, G., Friedman, B., Graßl, T., Ichikawa, T., Ioannidis, J. P., Lacy, P., McManus, R., Murray, A., Myers, M., Palatini, P., Parati, G., Quinn, D., Sarkis, J., Shennan, A. & 4 others, Usuda, T., Wang, J., Wu, C. O. & O'Brien, E., 1 Mar 2018, In : Journal of Hypertension. 36, 3, p. 472-478 7 p.

    Research output: Contribution to journalArticle

  11. Improving the accuracy of blood pressure measurement: The influence of the European Society of Hypertension International Protocol (ESH-IP) for the validation of blood pressure measuring devices and future perspectives

    Stergiou, G. S., Asmar, R., Myers, M., Palatini, P., Parati, G., Shennan, A., Wang, J. & O'Brien, E., 1 Mar 2018, In : Journal of Hypertension. 36, 3, p. 479-487 9 p.

    Research output: Contribution to journalEditorial

  12. Müllerian tract anomalies and urinary tract infections

    Teoh, P. J., Ridout, A., Carter, J. & Shennan, A. H., 1 Mar 2018, In : Acta Obstetricia et Gynecologica Scandinavica. 97, 3, p. 357 1 p.

    Research output: Contribution to journalLetter

  13. Predicting delivery of a small-for-gestational-age infant and adverse perinatal outcome in women with suspected pre-eclampsia

    Griffin, M., Seed, P. T., Duckworth, S., North, R., Myers, J., Mackillop, L., Simpson, N., Waugh, J., Medicine, M., Anumba, D., Kenny, L. C., Redman, C. W. G., Shennan, A. H. & Chappell, L. C., Mar 2018, In : Ultrasound in Obstetrics and Gynecology. 51, 3, p. 387–395

    Research output: Contribution to journalArticle

  14. Heterogeneous patterns of brain atrophy in Alzheimer's disease

    Poulakis, K., Pereira, J. B., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Wahlund, L-O. & Westman, E., 31 Jan 2018, In : Neurobiology of Aging.

    Research output: Contribution to journalArticle

  15. Women's experiences of tests and procedures carried out at a preterm birth surveillance clinic

    Carlisle, N., Carter, J., Radford, S. & Shennan, A., 12 Jan 2018, In : British Journal of Midwifery. 26, 1, p. 31-34

    Research output: Contribution to journalArticle

  16. The CRADLE vital signs alert: qualitative evaluation of a novel device designed for use in pregnancy by healthcare workers in low-resource settings

    Nathan, H. L., Boene, H., Munguambe, K., Sevene, E., Akeju, D., Adetoro, O. O., Bellad, M. B., De Greeff, A., Anthony, J., Hall, D. R., Steyn, W., Vidler, M., von Dadelszen, P., Chappell, L. C., Sandall, J., Shennan, A. H. & CLIP Working Group, 5 Jan 2018, In : Post reproductive health. 15, 1, p. 5 1 p.

    Research output: Contribution to journalArticle

  17. Cord Metabolic Profiles In Obese Pregnant Women; Insights Into Offspring Growth And Body Composition: Insights Into Offspring Growth And Body Composition

    Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. & UPBEAT Consortium, 1 Jan 2018, In : The Journal of clinical endocrinology and metabolism. 103, 1, p. 346–355

    Research output: Contribution to journalArticle

  18. CROWN initiative and preterm birth prevention: researchers and editors commit to implement core outcome sets

    van ‘t Hooft, J., Alfirevic, Z., Asztalos, E. V., Biggio, J. R., Dugoff, L., Hoffman, M., Lee, G., Mol, B. W., Pacagnella, R. C., Pajkrt, E., Saade, G. R., Shennan, A. H., Vayssière, C. & Khan, K. S., Jan 2018, In : BJOG: An International Journal of Obstetrics and Gynaecology. 125, 1, p. 8-11 4 p.

    Research output: Contribution to journalComment/debate

  19. 2017
  20. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

    Horgusluoglu-Moloch, E., Nho, K., Risacher, S. L., Kim, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 1 Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  21. Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

    C Vieira, M., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. & UPBEAT Consortium, 3 Nov 2017, In : BMC Medicine. 15, 1, p. 194

    Research output: Contribution to journalArticle

  22. A multicentre, randomised controlled trial of position during the late stages of labour in nulliparous women with an epidural: Clinical effectiveness and an economic evaluation (BUMPES)

    Bick, D., Briley, A., Brocklehurst, P., Hardy, P., Juszczak, E., Lynch, L., Macarthur, C., Moore, P., Nolan, M., Rivero-Arias, O., Sanders, J., Shennan, A. & Wilson, M., 1 Nov 2017, In : Health technology assessment (Winchester, England). 21, 65, p. 1-175 175 p.

    Research output: Contribution to journalArticle

  23. Upright versus lying down position in second stage of labour in nulliparous women with low dose epidural: BUMPES randomised controlled trial

    Bick, D., Briley, A., Brocklehurst, P., Hardy, P., Juszczak, E., Lynch, L., MacArthur, C., Moore, P., Nolan, M., Rivero-Arias, O., Sanders, J., Shennan, A. & Wilson, M., 21 Oct 2017, In : BMJ (Clinical research ed.). 359, 8126, p. 1-15 j4471.

    Research output: Contribution to journalArticle

  24. DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement

    Westwood, S., Baird, A. L., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Snowden, S. G., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J. & 2 others, Visser, P. J. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P361-P362

    Research output: Contribution to journalArticle

  25. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P243

    Research output: Contribution to journalPoster abstract

  26. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstract

  27. Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

    Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo-Sanchís, A., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P. & 2 others, Srivastava, D. P. & Killick, R., 19 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  28. Spot protein-creatinine ratio and spot albumin-creatinine ratio in the assessment of pre-eclampsia: A diagnostic accuracy study with decision-analytic model-based economic evaluation and acceptability analysis

    Waugh, J., Hooper, R., Lamb, E., Robson, S., Shennan, A., Milne, F., Price, C., Thangaratinam, S., Berdunov, V. & Bingham, J., 1 Oct 2017, In : Health technology assessment (Winchester, England). 21, 61, p. 1-90 90 p.

    Research output: Contribution to journalArticle

  29. Hormone-secreting adrenal tumours cause severe hypertension and high rates of poor pregnancy outcome: a UKOSS study with case control comparisons

    Quartermaine, G., Lambert, K., Rees, K., Seed, P. T., Dhanjal, M. K., Knight, M., McCance, D. R. & Williamson, C., 5 Sep 2017, In : BJOG.

    Research output: Contribution to journalArticle

  30. OP 2 Placental growth factor informed management of suspected pre-eclampsia and/or fetal growth restriction: The MAPPLE cohort study

    Sharp, A., Chappell, L., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., Hillerer, K. M., Fischer, T., Seed, P., Turner, M., Shennan, A. & Alfirevic, Z., 12 Aug 2017, In : Pregnancy Hypertension. 9, p. 9-10 2 p.

    Research output: Contribution to journalMeeting abstract

  31. OP 35 Incidence of pre-eclampsia in the UK in 2016–17

    Hendy, E., Vousden, N., Shennan, A. & Chappell, L., 12 Aug 2017, In : Pregnancy Hypertension. 9, p. 25 1 p.

    Research output: Contribution to journalMeeting abstract

  32. Metabolic profiling of gestational diabetes in obese women during pregnancy

    White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. & UPBEAT Consortium, 1 Aug 2017, In : Diabetologia. 60, 10, p. 1603-1912 10 p.

    Research output: Contribution to journalArticle

  33. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Winchester, L., Nevado-Holgado, A. J. & Lovestone, S., 20 Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P221

    Research output: Contribution to journalMeeting abstract

  34. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

    Rojo, A. I., Pajares, M., Rada, P., Nuñez, A., Nevado-Holgado, A. J., Killik, R., Van Leuven, F., Ribe, E., Lovestone, S., Yamamoto, M. & Cuadrado, A., 5 Jul 2017, In : Redox Biology.

    Research output: Contribution to journalArticle

  35. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

    Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I., Pearce, J. & 27 others, Streffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. JB., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

    Research output: Contribution to journalMeeting abstract

  36. HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies

    Schreiber, K., Breen, K., Cohen, H., Jacobsen, S., Middeldorp, S., Pavord, S., Regan, L., Roccatello, D., Robinson, S. E., Sciascia, S., Seed, P. T., Watkins, L. & Hunt, B. J., 13 Jun 2017, In : Seminars in Thrombosis and Hemostasis.

    Research output: Contribution to journalArticle

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