King's College London

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Research Outputs

  1. 2015
  2. Endothelial and platelet microparticles in patients with antiphospholipid antibodies

    Breen, K. A., Sanchez, K., Kirkman, N., Seed, P. T., Parmar, K., Moore, G. W. & Hunt, B. J., 1 Feb 2015, In : Thrombosis Research. 135, 2, p. 368-374 7 p.

    Research output: Contribution to journalArticle

  3. Association between maternal micronutrient status, oxidative stress and common genetic variants in antioxidant enzymes at 15 weeks' gestation in nulliparous women who subsequently develop pre-eclampsia

    Mistry, H. D., Gill, C. A., Kurlak, L. O., Seed, P. T., Hesketh, J. E., Méplan, C., Schomburg, L., Chappell, L. C., Morgan, L., Poston, L. & on behalf of SCOPE consortium, 1 Jan 2015, In : Free Radical Biology and Medicine. 78, p. 147-155 9 p.

    Research output: Contribution to journalArticle

  4. Shock index: An effective predictor of outcome in postpartum haemorrhage?

    Nathan, H. L., El Ayadi, A., Hezelgrave, N. L., Seed, P., Butrick, E., Miller, S., Briley, A., Bewley, S. & Shennan, A. H., 1 Jan 2015, In : BJOG: An International Journal of Obstetrics and Gynaecology. 122, 2, p. 268-275 8 p.

    Research output: Contribution to journalArticle

  5. Assessment of a Full Dilatation Cesarean Delivery Simulator

    Vousden, N., Hamakarim, Z., Briley, A., Girling, J., Seed, P. T., Tydeman, G. & Shennan, A. H., 2015, In : Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  6. Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts

    Khondoker, M., Newhouse, S., Westman, E., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Dobson, R. & Simmons, A., 2015, In : Journal of Alzheimer's disease : JAD. 45, 3, p. 851-864 14 p.

    Research output: Contribution to journalArticle

  7. Practical cut-offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment

    Ferreira, D., Cavallin, L., Larsson, E-M., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Wahlund, L-O., Westman, E. & The AddNeuroMed consortium, the Alzheimer's Disease Neuroimaging, Initiative, 2015, In : Journal of Internal Medicine. 14 p.

    Research output: Contribution to journalArticle

  8. Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

    Vos, S. J. B., Verhey, F., Frölich, L., Kornhuber, J., Wiltfang, J., Maier, W., Peters, O., Rüther, E., Nobili, F., Morbelli, S., Frisoni, G. B., Drzezga, A., Didic, M., van Berckel, B. N. M., Simmons, A., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B. & 20 others, Lovestone, S., Muscio, C., Herukka, S-K., Salmon, E., Bastin, C., Wallin, A., Nordlund, A., de Mendonça, A., Silva, D., Santana, I., Lemos, R., Engelborghs, S., Van der Mussele, S., Freund-Levi, Y., Wallin, Å. K., Hampel, H., van der Flier, W., Scheltens, P., Visser, P. J. & The Alzheimer’s Disease Neuroimaging Initiative, 2015, In : Brain. 12 p.

    Research output: Contribution to journalArticle

  9. Protective variant for hippocampal atrophy identified by whole exome sequencing

    Nho, K., Kim, S., Risacher, S. L., Shen, L., Corneveaux, J. J., Swaminathan, S., Lin, H., Ramanan, V. K., Liu, Y., Foroud, T. M., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. L. & 15 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J., Saykin, A. J. & for the Indiana Memory, Aging Study, 2015, In : Annals of Neurology.

    Research output: Contribution to journalArticle

  10. Science forum: RIPOSTE: a framework for improving the design and analysis of laboratory-based research.

    Masca, N. G. D., Hensor, E. M. A., Cornelius, V. R., Buffa, F. M., Marriott, H. M., Eales, J. M., Messenger, M. P., Anderson, A. E., Boot, C., Bunce, C., Goldin, R. D., Harris, J., Hinchliffe, R. F., Junaid, H., Kingston, S., Martin-Ruiz, C., Nelson, C. P., Peacock, J., Seed, P. T., Shinkins, B. & 4 others, Staples, K. J., Toombs, J., Wright, A. K. A. & Teare, M. D., 2015, eLife. p. e05519 (eLife; vol. 4).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  11. 2014
  12. Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

    Proitsi, P., Lupton, M. K., Velayudhan, L., Hunter, G., Newhouse, S., Lin, K., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Craig, D., Todd, S., Johnston, J. A., McGuinness, B., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Passmore, P. A., Sims, R. & 7 others, Williams, J., Brayne, C., Stewart, R., Sham, P., Lovestone, S., Powell, J. F. & Alzheimer's Disease Neuroimaging Initiative, Dec 2014, In : Neurobiology of Aging. 35, 12, p. 2883.e3-2883.e10 8 p., 2883.

    Research output: Contribution to journalArticle

  13. Plasma proteins predict conversion to dementia from prodromal disease

    Hye, A., Riddoch-Contreras, J., Baird, A. L., Ashton, N., Bazenet, C., Leung, R., Westman, E., Simmons, A., Dobson, R., Sattlecker, M., Lupton, M., Lunnon, K., Keohane, A., Ward, M., Pike, I., Zucht, H. D., Pepin, D., Zheng, W., Tunnicliffe, A., Richardson, J. & 7 others, Gauthier, S., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B. & Lovestone, S., 1 Nov 2014, In : Alzheimer's & dementia : the journal of the Alzheimer's Association. 10, 6, p. 799–807.e2 11 p.

    Research output: Contribution to journalArticle

  14. AN INTERVENTION TRIAL FOR PEOPLE WITH EPILEPSY ATTENDING A&E

    Ridsdale, L. L., McCrone, P. R., Morgan, M. A., Seed, P., Goldstein, L. H. & Noble, A. J., 1 Oct 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, e4, p. A20 1 p., 075.

    Research output: Contribution to journalMeeting abstract

  15. Endocervical and high vaginal quantitative fetal fibronectin in predicting preterm birth

    Kuhrt, K., Unwin, C., Hezelgrave, N., Seed, P. & Shennan, A., 1 Oct 2014, In : JOURNAL OF MATERNAL FETAL AND NEONATAL MEDICINE. 27, 15, p. 1576-1579 4 p.

    Research output: Contribution to journalArticle

  16. Global challenges in the identification and management of pre-eclampsia

    Hall, M., Hezelgrave Elliott, N. & Shennan, A. H., 1 Oct 2014, Advances in Medicine and Biology. Nova Science Publishers Inc, Vol. 80. p. 89-102 14 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  17. Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

    Proitsi, P., Lupton, M. K., Velayudhan, L., Newhouse, S., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Williams, J., Harold, D., Sims, R., Gerrish, A., Chapman, J., Escott-Price, V., Abraham, R., Hollingworth, P. & 74 others, Hamshere, M., Singh Pahwa, J., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A., Williams, K., Lovestone, S., Powell, J. F., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K., Passmore, P., Craig, D., Mcguinness, B., Johnston, J. A., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Guerreiro, R., Singleton, A., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Heun, R., Schürmann, B., Ramirez, A., Becker, T., Herold, C., Lacour, A., Drichel, D., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., Mcquillin, A., Gwilliam, R., Deloukas, P., Nöthen, M. M., Holmans, P., O'donovan, M., Owen, M. J., Williams, J., Stewart, R. & Sham, P., 16 Sep 2014, In : PLoS Medicine. 11, 9

    Research output: Contribution to journalArticle

  18. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

    Lunnon, K., Smith, R., Hannon, E., De Jager, P. L., Srivastava, G., Volta, M., Troakes, C., Al-Sarraj, S., Burrage, J., Macdonald, R., Condliffe, D., Harries, L. W., Katsel, P., Haroutunian, V., Kaminsky, Z., Joachim, C., Powell, J., Lovestone, S., Bennett, D. A., Schalkwyk, L. C. & 1 others, Mill, J., Sep 2014, In : Nature Neuroscience. 17, 9, p. 1164-1170 7 p.

    Research output: Contribution to journalArticle

  19. Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain

    Condliffe, D., Wong, A., Troakes, C., Proitsi, P., Patel, Y., Chouliaras, L., Fernandes, C., Cooper, J., Lovestone, S., Schalkwyk, L., Mill, J. & Lunnon, K., Aug 2014, In : Neurobiology of Aging. 35, 8, p. 1850-1854 5 p.

    Research output: Contribution to journalArticle

  20. Prediction of gestational diabetes in obese pregnant women from the UK Pregnancies Better Eating and Activity (UPBEAT) pilot trial

    Maitland, R. A., Seed, P. T., Briley, A. L., Homsy, M., Thomas, S., Pasupathy, D., Robson, S. C., Nelson, S. M., Sattar, N., Poston, L. & UPBEAT Trial Consortium, Aug 2014, In : Diabetic Medicine. 31, 8, p. 963-970 8 p.

    Research output: Contribution to journalArticle

  21. A GENOME-WIDE META-ANALYSIS OF PLASMA CLUSTERIN LEVELS IN THE CHARGE CONSORTIUM

    Chouraki, V. A., Jakobsdottir, J., Mather, K., Adams, H., Mollon, J., Oldmeadow, C., Thalamuthu, A., Tanaka, T., Scott, R., Levy, D., Holliday, L., Song, F., Thambisetty, M., Poljak, A., Eiriksdottir, G., Sachdev, P. S., Gupta, V. B., Martins, R., Launer, L., Dobson, R. & 6 others, Brodaty, H., Attia, J., Lovestone, S., Gudnason, V., Ikram, M. & Seshadri, S., Jul 2014, In : Alzheimer's Dementia: The Journal of the Alzheimer's Association. 10, 4, Supplement, p. P652-P653 2 p., P3-071.

    Research output: Contribution to journalPoster abstract

  22. Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease

    Escott-Price, V., Bellenguez, C., Wang, L-S., Choi, S-H., Harold, D., Jones, L., Holmans, P., Gerrish, A., Vedernikov, A., Richards, A., DeStefano, A. L., Lambert, J-C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Jun, G., Bis, J. C., Beecham, G. W., Grenier-Boley, B., Russo, G. & 31 others, Thornton-Wells, T. A., Denning, N., Smith, A. V., Chouraki, V., Thomas, C., Ikram, M. A., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C-F., Schmidt, H., Kunkle, B., Dunstan, M. L., Vronskaya, M., Johnson, A. D., Ruiz, A., Bihoreau, M-T., Reitz, C., Pasquier, F., Hollingworth, P., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Lovestone, S., Proitsi, P., Powell, J. F. & United Kingdom Brain Expression, 12 Jun 2014, In : PL o S One . 9, 6, 13 p., e94661.

    Research output: Contribution to journalArticle

  23. Association between response to ovarian stimulation and miscarriage following IVF: an analysis of 124 351 IVF pregnancies

    Sunkara, S., Khalaf, Y., Maheshwari, A., Seed, P. & Coomarasamy, A., Jun 2014, In : Human Reproduction. 29, 6, p. 1218-1224 7 p.

    Research output: Contribution to journalArticle

  24. Cervical cerclage: an established intervention with neglected potential?

    Story, L. & Shennan, A., May 2014, In : European Journal of Obstetrics Gynecology and Reproductive Biology. 176, p. 17-19 3 p.

    Research output: Contribution to journalLiterature review

  25. How placental growth factor detection might improve diagnosis and management of pre-eclampsia

    Duhig, K. E., Chappell, L. C. & Shennan, A. H., May 2014, In : EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 14, 4, p. 403-406 4 p., N/A.

    Research output: Contribution to journalEditorial

  26. Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: A prospective population-based case-control study

    Geenes, V., Chappell, L. C., Seed, P. T., Steer, P. J., Knight, M. & Williamson, C., Apr 2014, In : Hepatology. 59, 4, p. 1482-1491 10 p.

    Research output: Contribution to journalArticle

  27. Clinical applications of biomarkers in preeclampsia

    Griffin, M. & Shennan, A. H., Apr 2014, In : Biomarkers in Medicine. 8, 4, p. 459-470 12 p.

    Research output: Contribution to journalLiterature review

  28. Fetal fibronectin as a biomarker of preterm labor: a review of the literature and advances in its clinical use

    Foster, C. & Shennan, A. H., Apr 2014, In : Biomarkers in Medicine. 8, 4, p. 471-484 14 p.

    Research output: Contribution to journalLiterature review

  29. Short-term prediction of preeclampsia: how close are we?

    Chappell, L. C., Bramham, K. & Shennan, A. H., Apr 2014, In : Biomarkers in Medicine. 8, 4, p. 455-458 4 p., N/A.

    Research output: Contribution to journalEditorial

  30. Dynamin protein in stroke and vascular dementia

    Mulugeta, E., Vallortigara, J., Francis, P. T., Hye, A., Kalaria, R. N., Perry, E. K., Lovestone, S. & Ballard, C. G., 20 Mar 2014, In : Neuroscience Letters. 563, N/A, p. 118-122 5 p., N/A.

    Research output: Contribution to journalArticle

  31. No Differences in Hippocampal Volume between Carriers and Non-Carriers of the ApoE ε4 and ε2 Alleles in Young Healthy Adolescents

    Khan, W., Giampietro, V., Ginestet, C., Dell' Acqua, F., Bouls, D., Newhouse, S., Dobson, R., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Büchel, C., Conrod, P., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Lemaître, H., Nees, F. & 10 others, Paus, T., Pausova, Z., Rietschel, M., Smolka, M. N., Ströhle, A., Gallinat, J., Westman, E., Schumann, G., Lovestone, S. & Simmons, A., 1 Mar 2014, In : Journal of Alzheimer's disease : JAD. 40, 1, p. 37-43 7 p.

    Research output: Contribution to journalArticle

  32. A complex intervention to improve pregnancy outcome in obese women; the UPBEAT randomised controlled trial: the UPBEAT randomised controlled trial

    Briley, A. L., Barr, S., Badger, S., Bell, R., Croker, H., Godfrey, K. M., Holmes, B., Kinnunen, T. I., Nelson, S. M., Oteng-Ntim, E., Patel, N., Robson, S. C., Sandall, J., Sanders, T., Sattar, N., Seed, P. T., Wardle, J. & Poston, L., 18 Feb 2014, In : BMC Pregnancy and Childbirth. 14, 1, p. N/A 9 p., 74.

    Research output: Contribution to journalArticle

  33. Low-dose aspirin vs low-dose aspirin plus low-intensity warfarin in thromboprophylaxis: a prospective, multicentre, randomized, open, controlled trial in patients positive for antiphospholipid antibodies (ALIWAPAS)

    Cuadrado, M. J., Bertolaccini, M. L., Seed, P. T., Tektonidou, M. G., Aguirre, A., Mico, L., Gordon, C., Ruiz-Irastorza, G., Egurbide, M. V., Gil, A., Espinosa, G., Houssiau, F., Rahman, A., Martin, H., McHugh, N., Galindo, M., Akil, M., Amigo, M. C., Murru, V. & Khamashta, M. A., 2 Feb 2014, In : Rheumatology (Oxford, England). 53, 2, p. 275-284 10 p., N/A.

    Research output: Contribution to journalArticle

  34. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease

    Whiley, L., Sen, A., Heaton, J., Proitsi, P., Garcia-Gomez, D., Leung, R., Smith, N., Thambisetty, M., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Lovestone, S. & Legido Quigley, C., 1 Feb 2014, In : Neurobiology of Aging. 35, 2, p. 271-278 8 p.

    Research output: Contribution to journalArticle

  35. Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

    Proitsi, P., Lee, S. H., Lunnon, K., Keohane, A., Powell, J., Troakes, C., Al-Sarraj, S., Furney, S., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Hodges, A. & AddNeuroMed Consortium, Feb 2014, In : Neurobiology of Aging. 35, 2, p. 279-290 12 p.

    Research output: Contribution to journalArticle

  36. Associations between intimate partner violence and termination of pregnancy: a systematic review and meta-analysis

    Hall, M., Chappell, L. C., Parnell, B. L., Seed, P. T. & Bewley, S., 7 Jan 2014, In : PL o S Medicine. 11, 1, 25 p., e1001581.

    Research output: Contribution to journalReview article

  37. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

    Killick, R., Ribe, E. M., Al-Shawi, R., Malik, B., Hooper, C., Fernandes, C., Dobson, R., Nolan, P. M., Lourdusamy, A., Furney, S., Lin, K., Breen, G., Wroe, R., To, A. W. M., Leroy, K., Causevic, M., Usardi, A., Robinson, M., Noble, W., Williamson, R. & 9 others, Lunnon, K., Kellie, S., Reynolds, C. H., Bazenet, C., Hodges, A., Brion, J-P., Stephenson, J., Paul Simons, J. & Lovestone, S., 1 Jan 2014, In : Molecular Psychiatry. 19, 1, p. 88-98 11 p.

    Research output: Contribution to journalArticle

  38. Developing novel blood-based biomarkers for Alzheimer's disease

    Snyder, H. M., Carrillo, M. C., Grodstein, F., Henriksen, K., Jeromin, A., Lovestone, S., Mielke, M. M., O'Bryant, S., Sarasa, M., Sjøgren, M., Soares, H., Teeling, J., Trushina, E., Ward, M., West, T., Bain, L. J., Shineman, D. W., Weiner, M. & Fillit, H. M., Jan 2014, In : Alzheimer's & Dementia. 10, 1, p. 109-114 6 p.

    Research output: Contribution to journalArticle

  39. Does adding milk to tea delay gastric emptying?

    Hillyard, S., Cowman, S., Ramasundaram, R., Seed, P. T. & O'Sullivan, G., Jan 2014, In : British Journal of Anaesthesia. 112, 1, p. 66-71 6 p.

    Research output: Contribution to journalArticle

  40. Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort

    Aguilar, C., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Lovestone, S., Wahlund, L-O., Simmons, A., Westman, E. & AddNeuroMed Consortium, 2014, In : Frontiers in Aging Neuroscience. 6, 12 p., 145.

    Research output: Contribution to journalArticle

  41. Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease in Two Independent Cohorts

    Khan, W. W., Westman, E., Jones, N., Wahlund, L-O., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Spenger, C., Lovestone, S., Muehlboeck, J-S., Simmons, A. & for the AddNeuroMed consortium and for the Alzheimer’s Disease Neuroimaging Initiative, 2014, In : Brain topography. 14 p.

    Research output: Contribution to journalArticle

  42. CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: A prospective AddNeuroMed study

    Paajanen, T., Hänninen, T., Tunnard, C., Hallikainen, M., Mecocci, P., Sobow, T., Tsolaki, M., Vellas, B., Lovestone, S. & Soininen, H., 2014, In : JOURNAL OF ALZHEIMERS DISEASE. 39, 3, p. 679-690 12 p.

    Research output: Contribution to journalArticle

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