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Research Outputs

  1. 2019
  2. A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort

    Stamate, D., Kim, M., Proitsi, P., Westwood, S., Baird, A., Nevado-Holgado, A., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Teunissen, C. E., Kate, M. T., Scheltens, P., Gabel, S., Meersmans, K., Blin, O., Richardson, J., De Roeck, E., Engelborghs, S., Sleegers, K. & 25 others, Bordet, R., Ramit, L., Kettunen, P., Tsolaki, M., Verhey, F., Alcolea, D., Lléo, A., Peyratout, G., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Popp, J., Martinez-Lage, P., Bertram, L., Blennow, K., Zetterberg, H., Streffer, J., Visser, P. J., Lovestone, S. & Legido-Quigley, C., 1 Jan 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 933-938 6 p.

    Research output: Contribution to journalArticle

  3. Differential associations of IL-4 with hippocampal subfields in mild cognitive impairment and Alzheimer's disease

    AddNeuroMed Project, 1 Jan 2019, In : Frontiers in Aging Neuroscience. 11, JAN, 439.

    Research output: Contribution to journalArticle

  4. Temporal and external validation of the fullPIERS model for the prediction of adverse maternal outcomes in women with pre-eclampsia

    Ukah, U. V., Payne, B., Karjalainen, H., Kortelainen, E., Seed, P. T., Conti-Ramsden, F. I., Cao, V., Laivuori, H., Hutcheon, J., Chappell, L., Ansermino, J. M., Vatish, M., Redman, C., Lee, T., Li, L., Magee, L. A. & von Dadelszen, P., Jan 2019, In : Pregnancy Hypertension. 15, p. 42-50 9 p.

    Research output: Contribution to journalArticle

  5. MAVRIC: A Multicentre Randomised Controlled Trial of Transabdominal Versus Transvaginal Cervical Cerclage

    Shennan, A., Chandiramani, M., Bennett, P., David, A. L., Girling, J., Ridout, A., Seed, P. T., Simpson, N., Thornton, S., Tydeman, G., Quenby, S. & Carter, J., 2019, In : American Journal of Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  6. 2018
  7. Rationale & design of the PROMISES study: A prospective assessment and validation study of salivary progesterone as a test for preterm birth in pregnant women from rural India

    Sharma, P., Khan, S., Ghule, M., Shivkumar, V. B., Dargan, R., Seed, P. T., Sarkar, A., Mehra, S., Shivkumar, P. V. & Tribe, R. M., 22 Dec 2018, In : Reproductive Health. 15, 1, 215.

    Research output: Contribution to journalArticle

  8. Stability of graph theoretical measures in structural brain networks in Alzheimer’s disease

    Mårtensson, G., Pereira, J. B., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Volpe, G. & Westman, E., 1 Dec 2018, In : Scientific Reports. 8, 1, 11592.

    Research output: Contribution to journalArticle

  9. The impact of ethnicity on adverse perinatal outcome in women with chronic hypertension: a cohort study

    Webster, L. M., Bramham, K., Seed, P. T., Homsy, M., Widdows, K., Webb, A. J., Nelson-Piercy, C., Magee, L., Thilaganathan, B., Myers, J. E. & Chappell, L. C., 14 Oct 2018, In : Ultrasound in Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  10. MRI predictors of amyloid pathology: Results from the EMIF-AD Multimodal Biomarker Discovery study

    Ten Kate, M., Redolfi, A., Peira, E., Bos, I., Vos, S. J., Vandenberghe, R., Gabel, S., Schaeverbeke, J., Scheltens, P., Blin, O., Richardson, J. C., Bordet, R., Wallin, A., Eckerstrom, C., Molinuevo, J. L., Engelborghs, S., Van Broeckhoven, C., Martinez-Lage, P., Popp, J., Tsolaki, M. & 17 others, Verhey, F. R. J., Baird, A. L., Legido-Quigley, C., Bertram, L., Dobricic, V., Zetterberg, H., Lovestone, S., Streffer, J., Bianchetti, S., Novak, G. P., Revillard, J., Gordon, M. F., Xie, Z., Wottschel, V., Frisoni, G., Visser, P. J. & Barkhof, F., 27 Sep 2018, In : Alzheimer's Research and Therapy. 10, 1, 100.

    Research output: Contribution to journalArticle

  11. A Slow-Digesting, Low-Glycemic Load Nutritional Beverage Improves Glucose Tolerance in Obese Pregnant Women Without Gestational Diabetes

    Maitland, R., Patel, N., Barr, S., Sherry, C., Marriage, B., Seed, P., Fernandez, L. G., Pedrosa, J. M. L., Murphy, H., Rueda, R. & Poston, L., 11 Sep 2018, In : Diabetes Technology and Therapeutics. 20, 10, p. 672-680 9 p.

    Research output: Contribution to journalArticle

  12. Creating biobanks in low and middle-income countries to improve knowledge: The PREPARE initiative

    De Oliveira, L., Dias, M. A. B., Jeyabalan, A., Payne, B., Redman, C. W., Magee, L., Poston, L., Chappell, L., Seed, P., von Dadelszen, P. & Roberts, J. M., Jul 2018, In : Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13, p. 62-64 3 p.

    Research output: Contribution to journalArticle

  13. Gestational diabetes modifies the association between PlGF in early pregnancy and preeclampsia in women with obesity

    Vieira, M. C., Begum, S., Seed, P. T., Badran, D., Briley, A. L., Gill, C., Godfrey, K. M., Lawlor, D. A., Nelson, S. M., Patel, N., Sattar, N., White, S. L., Poston, L., Pasupathy, D. & UPBEAT Consortium, Jul 2018, In : Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13, p. 267-272

    Research output: Contribution to journalArticle

  14. Interpregnancy weight change and adverse pregnancy outcomes: A systematic review and meta-analysis

    Oteng-Ntim, E., Mononen, S., Sawicki, O., Seed, P. T., Bick, D. & Poston, L., Jun 2018, In : BMJ open. 8, 6, 14 p., e018778.

    Research output: Contribution to journalReview article

  15. Evaluation of a novel vital sign device to reduce maternal mortality and morbidity in low-resource settings: a mixed method feasibility study for the CRADLE-3 trial

    Vousden, N., Lawley, E., Nathan, H. L., Seed, P. T., Brown, A., Muchengwa, T., Charantimath, U., Bellad, M., Gidiri, M. F., Goudar, S., Chappell, L. C., Sandall, J., Shennan, A. H. & CRADLE Trial Collaborative Group, 27 Apr 2018, In : BMC Pregnancy and Childbirth. 18, 1, 115.

    Research output: Contribution to journalArticle

  16. Placental Growth Factor informed management of suspected pre-eclampsia or fetal growth restriction: The MAPPLE cohort study

    Sharp, A., Chappell, L. C., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., Hillerer, K. M., Fischer, T., Seed, P. T., Turner, M., Shennan, A. H. & Alfirevic, Z., 26 Mar 2018, In : Pregnancy Hypertension. 18 p.

    Research output: Contribution to journalArticle

  17. Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

    Smith, R. G., Hannon, E., De Jager, P. L., Chibnik, L., Lott, S. J., Condliffe, D., Smith, A. R., Haroutunian, V., Troakes, C., Al-Sarraj, S., Bennett, D. A., Powell, J., Lovestone, S., Schalkwyk, L., Mill, J. & Lunnon, K., 15 Mar 2018, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  18. Predicting delivery of a small-for-gestational-age infant and adverse perinatal outcome in women with suspected pre-eclampsia

    Griffin, M., Seed, P. T., Duckworth, S., North, R., Myers, J., Mackillop, L., Simpson, N., Waugh, J., Medicine, M., Anumba, D., Kenny, L. C., Redman, C. W. G., Shennan, A. H. & Chappell, L. C., Mar 2018, In : Ultrasound in Obstetrics and Gynecology. 51, 3, p. 387–395

    Research output: Contribution to journalArticle

  19. Heterogeneous patterns of brain atrophy in Alzheimer's disease

    Poulakis, K., Pereira, J. B., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Wahlund, L-O. & Westman, E., 31 Jan 2018, In : Neurobiology of Aging.

    Research output: Contribution to journalArticle

  20. Cord Metabolic Profiles In Obese Pregnant Women; Insights Into Offspring Growth And Body Composition: Insights Into Offspring Growth And Body Composition

    Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. & UPBEAT Consortium, 1 Jan 2018, In : The Journal of clinical endocrinology and metabolism. 103, 1, p. 346–355

    Research output: Contribution to journalArticle

  21. 2017
  22. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

    Horgusluoglu-Moloch, E., Nho, K., Risacher, S. L., Kim, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 1 Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  23. Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

    C Vieira, M., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. & UPBEAT Consortium, 3 Nov 2017, In : BMC Medicine. 15, 1, p. 194

    Research output: Contribution to journalArticle

  24. DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement

    Westwood, S., Baird, A. L., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Snowden, S. G., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J. & 2 others, Visser, P. J. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P361-P362

    Research output: Contribution to journalArticle

  25. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P243

    Research output: Contribution to journalPoster abstract

  26. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstract

  27. Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

    Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo-Sanchís, A., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P. & 2 others, Srivastava, D. P. & Killick, R., 19 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  28. Hormone-secreting adrenal tumours cause severe hypertension and high rates of poor pregnancy outcome: a UKOSS study with case control comparisons

    Quartermaine, G., Lambert, K., Rees, K., Seed, P. T., Dhanjal, M. K., Knight, M., McCance, D. R. & Williamson, C., 5 Sep 2017, In : BJOG.

    Research output: Contribution to journalArticle

  29. OP 2 Placental growth factor informed management of suspected pre-eclampsia and/or fetal growth restriction: The MAPPLE cohort study

    Sharp, A., Chappell, L., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., Hillerer, K. M., Fischer, T., Seed, P., Turner, M., Shennan, A. & Alfirevic, Z., 12 Aug 2017, In : Pregnancy Hypertension. 9, p. 9-10 2 p.

    Research output: Contribution to journalMeeting abstract

  30. Metabolic profiling of gestational diabetes in obese women during pregnancy

    White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. & UPBEAT Consortium, 1 Aug 2017, In : Diabetologia. 60, 10, p. 1603-1912 10 p.

    Research output: Contribution to journalArticle

  31. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Winchester, L., Nevado-Holgado, A. J. & Lovestone, S., 20 Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P221

    Research output: Contribution to journalMeeting abstract

  32. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

    Rojo, A. I., Pajares, M., Rada, P., Nuñez, A., Nevado-Holgado, A. J., Killik, R., Van Leuven, F., Ribe, E., Lovestone, S., Yamamoto, M. & Cuadrado, A., 5 Jul 2017, In : Redox Biology.

    Research output: Contribution to journalArticle

  33. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

    Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I., Pearce, J. & 27 others, Streffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. JB., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

    Research output: Contribution to journalMeeting abstract

  34. HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies

    Schreiber, K., Breen, K., Cohen, H., Jacobsen, S., Middeldorp, S., Pavord, S., Regan, L., Roccatello, D., Robinson, S. E., Sciascia, S., Seed, P. T., Watkins, L. & Hunt, B. J., 13 Jun 2017, In : Seminars in Thrombosis and Hemostasis.

    Research output: Contribution to journalArticle

  35. Maternal BMI and diabetes in pregnancy: Investigating variations between ethnic groups using routine maternity data from London, UK

    Nishikawa, E., Oakley, L., Seed, P., Doyle, P. & Oteng-Ntim, E., 1 Jun 2017, In : PL o S One . 12, 6, e0179332.

    Research output: Contribution to journalArticle

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