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Research Outputs

  1. 2014
  2. No Differences in Hippocampal Volume between Carriers and Non-Carriers of the ApoE ε4 and ε2 Alleles in Young Healthy Adolescents

    Khan, W., Giampietro, V., Ginestet, C., Dell' Acqua, F., Bouls, D., Newhouse, S., Dobson, R., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Büchel, C., Conrod, P., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Lemaître, H., Nees, F. & 10 others, Paus, T., Pausova, Z., Rietschel, M., Smolka, M. N., Ströhle, A., Gallinat, J., Westman, E., Schumann, G., Lovestone, S. & Simmons, A., 1 Mar 2014, In : Journal of Alzheimer's disease : JAD. 40, 1, p. 37-43 7 p.

    Research output: Contribution to journalArticle

  3. A complex intervention to improve pregnancy outcome in obese women; the UPBEAT randomised controlled trial: the UPBEAT randomised controlled trial

    Briley, A. L., Barr, S., Badger, S., Bell, R., Croker, H., Godfrey, K. M., Holmes, B., Kinnunen, T. I., Nelson, S. M., Oteng-Ntim, E., Patel, N., Robson, S. C., Sandall, J., Sanders, T., Sattar, N., Seed, P. T., Wardle, J. & Poston, L., 18 Feb 2014, In : BMC Pregnancy and Childbirth. 14, 1, p. N/A 9 p., 74.

    Research output: Contribution to journalArticle

  4. Low-dose aspirin vs low-dose aspirin plus low-intensity warfarin in thromboprophylaxis: a prospective, multicentre, randomized, open, controlled trial in patients positive for antiphospholipid antibodies (ALIWAPAS)

    Cuadrado, M. J., Bertolaccini, M. L., Seed, P. T., Tektonidou, M. G., Aguirre, A., Mico, L., Gordon, C., Ruiz-Irastorza, G., Egurbide, M. V., Gil, A., Espinosa, G., Houssiau, F., Rahman, A., Martin, H., McHugh, N., Galindo, M., Akil, M., Amigo, M. C., Murru, V. & Khamashta, M. A., 2 Feb 2014, In : Rheumatology (Oxford, England). 53, 2, p. 275-284 10 p., N/A.

    Research output: Contribution to journalArticle

  5. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease

    Whiley, L., Sen, A., Heaton, J., Proitsi, P., Garcia-Gomez, D., Leung, R., Smith, N., Thambisetty, M., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Lovestone, S. & Legido Quigley, C., 1 Feb 2014, In : Neurobiology of Aging. 35, 2, p. 271-278 8 p.

    Research output: Contribution to journalArticle

  6. Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

    Proitsi, P., Lee, S. H., Lunnon, K., Keohane, A., Powell, J., Troakes, C., Al-Sarraj, S., Furney, S., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Hodges, A. & AddNeuroMed Consortium, Feb 2014, In : Neurobiology of Aging. 35, 2, p. 279-290 12 p.

    Research output: Contribution to journalArticle

  7. Associations between intimate partner violence and termination of pregnancy: a systematic review and meta-analysis

    Hall, M., Chappell, L. C., Parnell, B. L., Seed, P. T. & Bewley, S., 7 Jan 2014, In : PL o S Medicine. 11, 1, 25 p., e1001581.

    Research output: Contribution to journalReview article

  8. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

    Killick, R., Ribe, E. M., Al-Shawi, R., Malik, B., Hooper, C., Fernandes, C., Dobson, R., Nolan, P. M., Lourdusamy, A., Furney, S., Lin, K., Breen, G., Wroe, R., To, A. W. M., Leroy, K., Causevic, M., Usardi, A., Robinson, M., Noble, W., Williamson, R. & 9 others, Lunnon, K., Kellie, S., Reynolds, C. H., Bazenet, C., Hodges, A., Brion, J-P., Stephenson, J., Paul Simons, J. & Lovestone, S., 1 Jan 2014, In : Molecular Psychiatry. 19, 1, p. 88-98 11 p.

    Research output: Contribution to journalArticle

  9. Developing novel blood-based biomarkers for Alzheimer's disease

    Snyder, H. M., Carrillo, M. C., Grodstein, F., Henriksen, K., Jeromin, A., Lovestone, S., Mielke, M. M., O'Bryant, S., Sarasa, M., Sjøgren, M., Soares, H., Teeling, J., Trushina, E., Ward, M., West, T., Bain, L. J., Shineman, D. W., Weiner, M. & Fillit, H. M., Jan 2014, In : Alzheimer's & Dementia. 10, 1, p. 109-114 6 p.

    Research output: Contribution to journalArticle

  10. Does adding milk to tea delay gastric emptying?

    Hillyard, S., Cowman, S., Ramasundaram, R., Seed, P. T. & O'Sullivan, G., Jan 2014, In : British Journal of Anaesthesia. 112, 1, p. 66-71 6 p.

    Research output: Contribution to journalArticle

  11. Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort

    Aguilar, C., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Lovestone, S., Wahlund, L-O., Simmons, A., Westman, E. & AddNeuroMed Consortium, 2014, In : Frontiers in Aging Neuroscience. 6, 12 p., 145.

    Research output: Contribution to journalArticle

  12. Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease in Two Independent Cohorts

    Khan, W. W., Westman, E., Jones, N., Wahlund, L-O., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Spenger, C., Lovestone, S., Muehlboeck, J-S., Simmons, A. & for the AddNeuroMed consortium and for the Alzheimer’s Disease Neuroimaging Initiative, 2014, In : Brain topography. 14 p.

    Research output: Contribution to journalArticle

  13. CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: A prospective AddNeuroMed study

    Paajanen, T., Hänninen, T., Tunnard, C., Hallikainen, M., Mecocci, P., Sobow, T., Tsolaki, M., Vellas, B., Lovestone, S. & Soininen, H., 2014, In : JOURNAL OF ALZHEIMERS DISEASE. 39, 3, p. 679-690 12 p.

    Research output: Contribution to journalArticle

  14. Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study

    Kiddle, S. J., Sattlecker, M., Proitsi, P., Simmons, A., Westman, E., Bazenet, C., Nelson, S. K., Williams, S., Hodges, A., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Newhouse, S., Lovestone, S. & Dobson, R. J. B., 2014, In : JOURNAL OF ALZHEIMERS DISEASE. 38, 3, p. 515-531 17 p., N/A.

    Research output: Contribution to journalLiterature review

  15. Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis

    Bramham, K., Parnell, B., Nelson-Piercy, C., Seed, P. T., Poston, L. & Chappell, L. C., 2014, In : BMJ. 348, 7954, 20 p., g2301.

    Research output: Contribution to journalArticle

  16. Clopidogrel as prophylactic treatment for migraine: A pilot randomised, controlled study

    Chambers, J. B., Seed, P. T. & Ridsdale, L., 2014, In : Cephalalgia. 34, 14, p. 1163-1168 6 p.

    Research output: Contribution to journalArticle

  17. Developing a new model for patient recruitment in mental health services: A cohort study using Electronic Health Records

    Callard, F., Broadbent, M., Denis, M., Hotopf, M., Soncul, M., Wykes, T., Lovestone, S. & Stewart, R., 2014, In : BMJ open. 4, 12, e005654.

    Research output: Contribution to journalArticle

  18. Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness

    Lebedev, A. V., Westman, E., Van Westen, G. J. P., Kramberger, M. G., Lundervold, A., Aarsland, D., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S. & Simmons, A., 2014, In : NeuroImage: Clinical. 6, p. 115-125 11 p.

    Research output: Contribution to journalArticle

  19. 2013
  20. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Lambert, J-C., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., DeStefano, A. L., Bis, J. C., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Ikram, M. A., Zelenika, D., Vardarajan, B. N. & 34 others, Kamatani, Y., Lin, C-F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M-T., Choi, S-H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Lovestone, S., Proitsi, P., Powell, J. F., EADI, GERAD, ADGC & CHARGE, Dec 2013, In : Nature Genetics. 45, 12, p. 1452-1458 7 p., N/A.

    Research output: Contribution to journalArticle

  21. Exploration and confirmation of factors associated with uncomplicated pregnancy in nulliparous women: prospective cohort study

    Chappell, L. C., Seed, P. T., Myers, J., Taylor, R. S., Kenny, L. C., Dekker, G. A., Walker, J. J., McCowan, L. M. E., North, R. A. & Poston, L., 21 Nov 2013, In : BMJ. 347, 12 p., f6398.

    Research output: Contribution to journalArticle

  22. Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia

    Chappell, L., Duckworth, S., Seed, P., Griffin, M., Myers, J., Mackillop, L., Simons, N., Waugh, J., Anumba, D., Kenny, L. C., Redman, C. W. G. & Shennan, A., Nov 2013, In : Circulation (Baltimore). 128, 19, p. 2121-2131 10 p.

    Research output: Contribution to journalArticle

  23. Association of migraine aura with patent foramen ovale and atrial septal aneurysms

    Chambers, J., Seed, P. T. & Ridsdale, L., 9 Oct 2013, In : International Journal of Cardiology. 168, 4, p. 3949-3953 5 p.

    Research output: Contribution to journalArticle

  24. Duplex ultrasound volumetric flow analysis before and after hemodialysis in patients with brachio-cephalic fistulae

    Chowdhury, S., Goss, D., Mistry, H., Stephenson, M. A., Seed, P., Deane, C. & Valenti, D., 1 Oct 2013, In : The journal of vascular access. 14, 4, p. 342-347 6 p.

    Research output: Contribution to journalArticle

  25. Correction: Harnessing Clinical Psychiatric Data with an Electronic Assessment Tool (OPCRIT+): The Utility of Symptom Dimensions

    Brittain, P. J., Lobo, S. E. M., Rucker, J., Amarasinghe, M., Anilkumar, A. P. P., Baggaley, M., Banerjee, P., Bearn, J., Broadbent, M., Butler, M., Campbell, C. D., Cleare, A. J., Dratcu, L., Frangou, S., Gaughran, F., Goldin, M., Henke, A., Kern, N., Krayem, A., Mufti, F. & 18 others, McIvor, R., Needham-Bennett, H., Newman, S., Olajide, D., O'Flynn, D., Rao, R., Rehman, I. U., Seneviratne, G., Stahl, D., Suleman, S., Treasure, J., Tully, J., Veale, D., Stewart, R., McGuffin, P., Lovestone, S., Hotopf, M. & Schumann, G., 10 Sep 2013, In : PLoS ONE. 8, 9

    Research output: Contribution to journalArticle

  26. The importance of tau phosphorylation for neurodegenerative diseases

    Noble, W., Hanger, D., Miller, C. & Lovestone, S., 1 Jul 2013, In : Frontiers in Neurology. 4, 83

    Research output: Contribution to journalBook/Film/Article review

  27. Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

    Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J. & Saykin, A. J., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 739 1 p.

    Research output: Contribution to journalArticle

  28. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

    Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 18 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J., Saykin, A. J., MIRAGE Study, AddNeuroMed Consortium, Indiana Memory Aging Study & ADNI, Jul 2013, In : Molecular Psychiatry. 18, 7, p. 781-787 7 p., N/A.

    Research output: Contribution to journalArticle

  29. Inflammatory Proteins in Plasma Are Associated with Severity of Alzheimer's Disease

    Leung, R., Proitsi, P., Simmons, A., Lunnon, K., Guentert, A., Kronenberg, D., Pritchard, M., Tsolaki, M., Mecocci, P., Kloszewska, I., Vellas, B., Soininen, H., Wahlund, L-O. & Lovestone, S., 10 Jun 2013, In : PL o S One . 8, 6, 10 p., e64971.

    Research output: Contribution to journalArticle

  30. Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol

    Mangialasche, F., Westman, E., Kivipelto, M., Muehlboeck, J. -S., Cecchetti, R., Baglioni, M., Tarducci, R., Gobbi, G., Floridi, P., Soininen, H., Kloszewska, I., Tsolaki, M., Vellas, B., Spenger, C., Lovestone, S., Wahlund, L. -O., Simmons, A., Mecocci, P. & AddNeuroMed Consortium, Jun 2013, In : Journal of Internal Medicine. 273, 6, p. 602-621 20 p.

    Research output: Contribution to journalArticle

  31. Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment

    Aguilar, C., Westman, E., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Lovestone, S., Spenger, C., Simmons, A. & Wahlund, L-O., 30 May 2013, In : Psychiatry Research. Neuroimaging. 212, 2, p. 89-98 10 p., N/A.

    Research output: Contribution to journalArticle

  32. An MRI-based index to measure the severity of Alzheimer's disease-like structural pattern in subjects with mild cognitive impairment

    Spulber, G., Simmons, A., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Spenger, C., Lovestone, S., Wahlund, L-O., Westman, E., AddNeuroMed Consortium & Alzheimer Dis Neuroimaging Initiat, Apr 2013, In : Journal of Internal Medicine. 273, 4, p. 396-409 14 p.

    Research output: Contribution to journalArticle

  33. The Public Health Impact score: a new measure of public health effectiveness for general practices in England

    Ashworth, M., Schofield, P., Doran, T., Cookson, R., Sutton, M., Seed, P. T., Howe, A. & Fleetcroft, R., Apr 2013, In : British Journal of General Practice. 63, 609, p. e291-e299 9 p.

    Research output: Contribution to journalArticle

  34. Harnessing clinical psychiatric data with an electronic assessment tool (OPCRIT+): the utility of symptom dimensions

    Brittain, P. J., Lobo, S. E. M., Rucker, J., Amarasinghe, M., Anilkumar, A. P. P., Baggaley, M., Banerjee, P., Bearn, J., Broadbent, M., Butler, M., Campbell, C. D., Cleare, A. J., Dratcu, L., Frangou, S., Gaughran, F., Goldin, M., Henke, A., Kern, N., Krayem, A., Mufti, F. & 18 others, McIvor, R., Needham-Bennett, H., Newman, S., Olajide, D., O'Flynn, D., Rao, R., Rehman, I., Seneviratne, G., Stahl, D., Suleman, S., Treasure, J., Tully, J., Veale, D., Stewart, R., McGuffin, P., Lovestone, S., Hotopf, M. & Schumann, G., 8 Mar 2013, In : PLoS ONE. 8, 3, 8 p., e58790.

    Research output: Contribution to journalArticle

  35. Alzheimer Risk Varia2nt CLU and Brain Function During Aging

    Thambisetty, M., Beason-Held, L. L., An, Y., Kraut, M., Nalls, M., Hernandez, D. G., Singleton, A. B., Zonderman, A. B., Ferrucci, L., Lovestone, S. & Resnick, S. M., 1 Mar 2013, In : Biological psychiatry. 73, 5, p. 399-405 7 p., N/A.

    Research output: Contribution to journalArticle

  36. Development and validation of a measure of health literacy in the UK: the newest vital sign

    Rowlands, G., Khazaezadeh, N., Oteng-Ntim, E., Seed, P., Barr, S. & Weiss, B. D., 7 Feb 2013, In : BMC Public Health. 13, 9 p., 116.

    Research output: Contribution to journalArticle

  37. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH

    Killick, R., Hughes, T. R., Morgan, B. P. & Lovestone, S., 15 Jan 2013, In : Neuroscience Letters. 533, p. 96-99 4 p.

    Research output: Contribution to journalArticle

  38. Impact of Obesity on Pregnancy Outcome in Different Ethnic Groups: Calculating Population Attributable Fractions

    Oteng-Ntim, E., Kopeika, J., Seed, P., Wandiembe, S. & Doyle, P., 14 Jan 2013, In : PL o S One . 8, 1, 7 p., e53749.

    Research output: Contribution to journalArticle

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