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Research Outputs

  1. 2007
  2. Schizophrenia as a GSK-3 dysregulation disorder

    Lovestone, S., Killick, R., Di Forti, M. & Murray, R., Apr 2007, In : Trends in Neurosciences. 30, 4, p. 142 - 149 8 p.

    Research output: Contribution to journalLiterature review

  3. The Notch-1 intracellular domain is found in sub-nuclear bodies in SH-SY5Y neuroblastomas and in primary cortical neurons

    Hooper, C., Chapple, J. P., Lovestone, S. & Killick, R., 26 Mar 2007, In : Neuroscience Letters. 415, 2, p. 135 - 139 5 p.

    Research output: Contribution to journalArticle

  4. Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella

    Nayeem, N., Kerr, F., Naumann, H., Linehan, J., Lovestone, S. & Brandner, S., Mar 2007, In : Molecular and Cellular Neurosciences. 34, 3, p. 400 - 408 9 p.

    Research output: Contribution to journalArticle

  5. The effects of commonly prescribed drugs in patients with Alzheimer's disease on the rate of deterioration

    Ellul, J., Archer, N., Foy, C. M. L., Poppe, M., Boothby, H., Nicholas, H., Brown, R. G. & Lovestone, S., Mar 2007, In : Journal of Neurology, Neurosurgery and Psychiatry. 78, 3, p. 233 - 239 7 p.

    Research output: Contribution to journalArticle

  6. Glycogen synthase kinase-3 inhibition is integral to long-term potentiation

    Hooper, C., Markevich, V., Plattner, F., Killick, R., Schofield, E., Engel, T., Hernandez, F., Anderton, B., Rosenblum, K., Bliss, T., Cooke, S. F., Avila, J., Lucas, J. J., Giese, K. P., Stephenson, J. & Lovestone, S., Jan 2007, In : European Journal of Neuroscience. 25, 1, p. 81 - 86 6 p.

    Research output: Contribution to journalArticle

  7. Glycogen synthase kinase-3 inhibition is integral to long-term potentiation.

    Hooper, C., Markevich, V., Plattner, F., Killick, R., Schofield, E., Engel, T., Hernandez, F., Anderton, B. H., Rosenblum, K., Bliss, T. V. P., Cooke, S. F., Avila, J., Lucas, J. J., Giese, K. P., Stephenson, J. D. & Lovestone, S. H., Jan 2007, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  8. Antiplatelet agents for prevention of pre-eclampsia

    Chandiramani, M., Seed, P., Poston, L. & Shennan, A. H., 2007, In : The Lancet. 370, 9600, p. 1685 - 1685 1 p.

    Research output: Contribution to journalLetter

  9. Neurogenetics: Scientific and clinical advances

    Lovestone, S., 2007, In : International Psychogeriatrics. 19, 2, p. 337 - 338 2 p.

    Research output: Contribution to journalBook/Film/Article review

  10. 2006
  11. GSK3 alpha exhibits beta-catenin and tau directed kinase activities that are modulated by Wnt

    Asuni, A. A., Hooper, C., Reynolds, C. H., Lovestone, S., Anderton, B. H. & Killick, R., Dec 2006, In : European Journal of Neuroscience. 24, 12, p. 3387 - 3392 6 p.

    Research output: Contribution to journalArticle

  12. Proteome-based plasma biomarkers for Alzheimer's disease

    Hye, A., Lynham, S., Thambisetty, M., Causevic, M., Campbell, J., Byers, H. L., Hooper, C., Rijsdijk, F., Tabrizi, S. J., Banner, S., Shaw, C. E., Foy, C., Poppe, M., Archer, N., Hamilton, G., Powell, J., Brown, R. G., Sham, P., Ward, M. & Lovestone, S., Nov 2006, In : Brain. 129, 11, p. 3042 - 3050 9 p.

    Research output: Contribution to journalArticle

  13. TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones

    Hooper, C., Tavassoli, M., Chapple, J. P., Uwanogho, D., Goodyear, R., Melino, G., Lovestone, S. & Killick, R., Nov 2006, In : Journal of Neurochemistry. 99, 3, p. 989 - 999 11 p.

    Research output: Contribution to journalArticle

  14. Molecular staging of lymph nodes from 60 patients with mycosis fungoides and Sezary syndrome: correlation with histopathology and outcome suggests prognostic relevance in mycosis fungoides

    Fraser-Andrews, E. A., Mitchell, T., Ferreira, S., Seed, P. T., Russell-Jones, R., Calonje, E. & Whittaker, S. J., Oct 2006, In : British Journal of Dermatology. 155, 4, p. 756 - 762 7 p.

    Research output: Contribution to journalArticle

  15. The effect of small intramural uterine fibroids on the cumulative outcome of assisted conception

    Khalaf, Y., Ross, C., El-Toukhy, T., Hart, R., Seed, P. & Braude, P., Oct 2006, In : Human Reproduction. 21, 10, p. 2640 - 2644 5 p.

    Research output: Contribution to journalArticle

  16. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression

    Li, Y. H., Grupe, A., Rowland, C., Nowotny, P., Kauwe, J. S. K., Smemo, S., Hinrichs, A., Tacey, K., Toombs, T. A., Kwok, S., Catanese, J., White, T. J., Maxwell, T. J., Hollingworth, P., Abraham, R., Rubinsztein, D. C., Brayne, C., Wavrant-De Vrieze, F., Hardy, J., O'Donovan, M. & 6 others, Lovestone, S., Morris, J. C., Thal, L. J., Owen, M., Williams, J. & Goate, A., 1 Sep 2006, In : Human Molecular Genetics. 15, 17, p. 2560 - 2568 9 p.

    Research output: Contribution to journalArticle

  17. Four components describe behavioral symptoms in 1,120 individuals with late-onset Alzheimer's disease

    Hollingworth, P., Hamshere, M. L., Moskvina, V., Dowzell, K., Moore, P. J., Foy, C., Archer, N., Lynch, A., Lovestone, S., Brayne, C., Rubinsztein, D. C., Lawlor, B., Gill, M., Owen, M. J. & Williams, J., Sep 2006, In : Journal of the American Geriatrics Society. 54, 9, p. 1348 - 1354 7 p.

    Research output: Contribution to journalArticle

  18. Morbidity in expatriates - a prospective cohort study

    Patel, D., Easmon, C., Seed, P., Dow, C. & Snashall, D., Aug 2006, In : Occupational Medicine. 56, 5, p. 345 - 352 8 p.

    Research output: Contribution to journalArticle

  19. The NEO-FFI is a reliable measure of premorbid personality in patients with probable Alzheimer's disease

    Archer, N., Brown, R. G., Boothby, H., Foy, C., Nicholas, H. & Lovestone, S., May 2006, In : International Journal of Geriatric Psychiatry. 21, 5, p. 477 - 484 8 p.

    Research output: Contribution to journalArticle

  20. Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial

    Poston, L., Briley, A. L., Seed, P. T., Kelly, F. J. & Shennan, A. H., 8 Apr 2006, In : The Lancet. 367, 9517, p. 1145 - 1154 10 p.

    Research output: Contribution to journalArticle

  21. Overexpression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions

    Chee, F., Mudher, A., Newman, T. A., Cuttle, M., Lovestone, S. & Shepherd, D., Feb 2006, In : Biochemical Society Transactions. 34, 1, p. 88 - 90 3 p.

    Research output: Contribution to journalArticle

  22. Placental NAD(P)H oxidase mediated superoxide generation in early pregnancy

    Raijmakers, M. T. M., Burton, G. J., Jauniaux, E., Seed, P. T., Peters, W. H. M., Steegers, E. A. P. & Poston, L., Feb 2006, In : Placenta. 27, 2-3, p. 158 - 163 6 p.

    Research output: Contribution to journalArticle

  23. A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET study

    Shennan, A., Crawshaw, S., Briley, A., Hawken, J., Seed, P., Jones, G. & Poston, L., Jan 2006, In : BJOG. 113, 1, p. 65 - 74 10 p.

    Research output: Contribution to journalArticle

  24. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease

    Grupe, A., Li, Y. H., Rowland, C., Nowotny, P., Hinrichs, A. L., Smemo, S., Kauwe, J. S. K., Maxwell, T. J., Cherny, S., Doil, L., Tacey, K., van Luchene, R., Myers, A., Vrieze, F. W., Kaleem, M., Hollingworth, P., Jehu, L., Foy, C., Archer, N., Hamilton, G. & 15 others, Holmans, P., Morris, C. M., Catanese, J., Sninsky, J., White, T. J., Powell, J., Hardy, J., O'Donovan, M., Lovestone, S., Jones, L., Morris, J. C., Thal, L., Owen, M., Williams, J. & Goate, A., Jan 2006, In : American Journal of Human Genetics. 78, 1, p. 78 - 88 11 p.

    Research output: Contribution to journalArticle

  25. Plasma lipid profiles of women with intrahepatic cholestasis of pregnancy

    Dann, A. T., Kenyon, A. P., Wierzbicki, A. S., Seed, P. T., Shennan, A. H. & Tribe, R. M., Jan 2006, In : Obstetrics and Gynecology. 107, 1, p. 106 - 114 9 p.

    Research output: Contribution to journalArticle

  26. Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease

    Smemo, S., Nowotny, P., Hinrichs, A. L., Kauwe, J. S. K., Cherny, S., Erickson, K., Myers, A. J., Kaleem, M., Marlowe, L., Gibson, A. M., Hollingworth, P., O'Donovan, M. C., Morris, C. M., Holmans, P., Lovestone, S., Morris, J. C., Thal, L., Li, Y. H., Grupe, A., Hardy, J. & 3 others, Owen, M. J., Williams, J. & Goate, A., Jan 2006, In : Annals of Neurology. 59, 1, p. 21 - 26 6 p.

    Research output: Contribution to journalArticle

  27. Biomarkers in Alzheimer's disease

    Lovestone, S., 2006, In : JOURNAL OF NUTRITION HEALTH & AGING. 10, 2, p. 118 - 122 5 p.

    Research output: Contribution to journalArticle

  28. Hyperphosphorylation of tau and neurofilament by constitutive activation of CDK5 in PTEN deficient cerebellum

    Nayeem, N., Kerr, F., Naumann, H., Lovestone, S. & Brandner, S., 2006, In : Neuropathology and Applied Neurobiology. 32, 2, p. 226 - 226 1 p.

    Research output: Contribution to journalMeeting abstract

  29. TAp73a induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism

    Hooper, C., Killick, R., Tavassoli, M., Melino, G. & Lovestone, S., 2006, In : Neuroscience Letters. 401, 1-2, p. 30 - 34 5 p.

    Research output: Contribution to journalArticle

  30. 2005
  31. Measuring mental health outcomes in primary care: The psychometric properties of a new patient-generated outcome measure, 'PSYCHLOPS' ('psychological outcome profiles')

    Ashworth, M., Robinson, S. I., Godfrey, E., Shepherd, M., Evans, C., Seed, P., Parmentier, H. & Tylee, A., 1 Dec 2005, In : Primary Care Mental Health. 3, 4, p. 261-270 10 p.

    Research output: Contribution to journalArticle

  32. Hippocampal myo-inositol and cognitive ability in adults with Down syndrome - An in vivo proton magnetic resonance spectroscopy study

    Beacher, F., Simmons, A., Daly, E., Prasher, V., Adams, C., Margallo-Lana, M. L., Morris, R., Lovestone, S., Murphy, K. & Murphy, D. G. M., Dec 2005, In : Archives of General Psychiatry. 62, 12, p. 1360 - 1365 6 p.

    Research output: Contribution to journalArticle

  33. Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions

    Chee, F. C., Mudher, A., Cuttle, M. F., Newman, T. A., MacKay, D., Lovestone, S. & Shepherd, D., Dec 2005, In : Neurobiology of Disease. 20, 3, p. 918 - 928 11 p.

    Research output: Contribution to journalArticle

  34. Measurement of sunscreen immune protection factor in humans: a concensus paper.

    Fourtanier, A., Moyal, D., Maccario, J., Compan, D., Wolf, P., Quehenberger, F., Cooper, K., Baron, E., Halliday, G., Poon, T., Seed, P., Walker, S. L. & Young, A. R., Sep 2005, In : Journal of Investigative Dermatology. 125, 3, p. 403 - 409 7 p.

    Research output: Contribution to journalArticle

  35. The BDNF val66met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples

    Li, Y., Rowland, C., Tacey, K., Catanese, J., Sninsky, J., Hardy, J., Powell, J., Lovestone, S., Morris, J. C., Thal, L., Goate, A., Owen, M., Williams, J. & Grupe, A., Sep 2005, In : Molecular Psychiatry. 10, 9, p. 809 - 810 2 p.

    Research output: Contribution to journalLetter

  36. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme

    Nowotny, P., Hinrichs, A. L., Smemo, S., Kauwe, J. S. K., Maxwell, T., Holmans, P., Hamshere, M., Turic, D., Jehu, L., Hollingworth, P., Moore, P., Bryden, L., Myers, A., Doil, L. M., Tacey, K. M., Gibson, A. M., McKeith, I. G., Perry, R. H., Morris, C. M., Thal, L. & 8 others, Morris, J. C., O'Donovan, M. C., Lovestone, S., Grupe, A., Hardy, J., Owen, M. J., Williams, J. & Goate, A., 5 Jul 2005, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 136B, 1, p. 62 - 68 7 p.

    Research output: Contribution to journalArticle

  37. Anaesthesia for Caesarean section and neonatal acid-base status: a meta-analysis

    Reynolds, F. & Seed, P. T., Jul 2005, In : Anaesthesia. 60, 7, p. 636 - 653 18 p.

    Research output: Contribution to journalArticle

  38. School students as Drosophila experimenters

    Siyad, F., Griffiths, J., Janjua, F., Jackson, E., Rodrigues, I., Kerr, F., MacKay, D. & Lovestone, S., Jul 2005, In : PL o S Biology. 3, 7, p. 1179 - 1179 1 p.

    Research output: Contribution to journalLetter

  39. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease

    Holmans, P., Hamshere, M., Hollingworth, P., Rice, F., Tunstall, N., Jones, S., Moore, P., DeVrieze, F. W., Myers, A., Crook, R., Compton, D., Marshall, H., Meyer, D., Shears, S., Booth, J., Ramic, D., Williams, N., Norton, N., Abraham, R., Kehoe, P. & 9 others, Williams, H., Rudrasingham, V., O'Donovan, M., Jones, L., Hardy, J., Goate, A., Lovestone, S., Owen, M. & Williams, J., 5 May 2005, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 135B, 1, p. 24 - 32 9 p.

    Research output: Contribution to journalArticle

  40. Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation

    Holmes, C., Ballard, C., Lehmann, D., Smith, A. D., Beaumont, H., Day, I. N., Khan, M. N., Lovestone, S., McCulley, M., Morris, C. M., Munoz, D. G., O'Brien, K., Russ, C., Del Ser, T. & Warden, D., May 2005, In : Journal of Neurology, Neurosurgery and Psychiatry. 76, 5, p. 640 - 643 4 p.

    Research output: Contribution to journalArticle

  41. Optimal bedside urinanalysis for the detection of proteinuria in hypertensive pregnancy: a study of diagnostic accuracy

    Waugh, J., Bell, S. C., Kilby, M. D., Blackwell, C. N., Seed, P., Shennan, A. H. & Halligan, A., Apr 2005, In : British Journal of Obstetrics and Gynaecology. 112, 4, p. 412 - 417 6 p.

    Research output: Contribution to journalArticle

  42. Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing

    Deary, I. J., Hamilton, G., Hayward, C., Whalley, L. J., Powell, J., Starr, J. M. & Lovestone, S., 10 Jan 2005, In : Neuroscience Letters. 373, 2, p. 110 - 114 5 p.

    Research output: Contribution to journalArticle

  43. Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study

    Cook, L. J., Ho, L. W., Wang, L., Terrenoire, E., Brayne, C., Evans, J. G., Xuereb, J., Cairns, N. J., Turic, D., Hollingworth, P., Moore, P. J., Jehu, L., Archer, N., Walter, S., Foy, C., Edmondson, A., Powell, J., Lovestone, S., Williams, J. & Rubinsztein, D. C., 5 Jan 2005, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 132B, 1, p. 5 - 8 4 p.

    Research output: Contribution to journalArticle

  44. Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease

    Hye, A., Kerr, F., Archer, N., Foy, C., Poppe, M., Brown, R., Hamilton, G., Powell, J., Anderton, B. & Lovestone, S., 3 Jan 2005, In : Neuroscience Letters. 373, 1, p. 1 - 4 4 p.

    Research output: Contribution to journalArticle

  45. A combined proteomic and neuroimaging approach to identifying biomarkers in Alzheimer's disease

    Thambisetty, M., Hye, A., Foy, C., Poppe, M., Archer, N., Campbell, J., Ward, M. & Lovestone, S., 2005, In : Journal of the Neurological Sciences. 238, p. S303 - S304

    Research output: Contribution to journalMeeting abstract

  46. Abnormal plasma lipds in obstetric cholestasis are not affected by ursodeoxycholic acid

    Dann, A., Kenyon, A., Seed, P. T., Poston, L., Shennan, A. H. & Tribe, R. M., 2005, In : Journal of Obstetrics and Gynaecology. 25, p. S11 - S11

    Research output: Contribution to journalMeeting abstract

  47. Experience of using internet data management in a multi centre randomised control trial (vitamins in pre eclampsia)

    Briley, A., Poston, L., Seed, P. T., Kublickas, M., Westgren, M. & Shennan, A. H., 2005, Journal of Obstetrics and Gynaecology. Unknown Publisher, p. S43

    Research output: Chapter in Book/Report/Conference proceedingMeeting abstract

  48. Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease

    Li, Y. H., Hollingworth, P., Moore, P., Foy, C., Archer, N., Powell, J., Nowotny, P., Holmans, P., O'Donovan, M., Tacey, K., Doil, L., van Luchene, R., Garcia, V., Rowland, C., Lau, K., Cantanese, J., Sninsky, J., Hardy, J., Thal, L., Morris, J. C. & 5 others, Goate, A., Lovestone, S., Owen, M., Williams, J. & Grupe, A., 2005, In : Human Mutation. 25, 3, p. 270 - 277 8 p.

    Research output: Contribution to journalArticle

  49. Genetic influences on the psychotic symptomatology of Alzheimer's disease

    Proitsi, P., Hamilton, G., Hollingworth, P., Jehu, L., Owen, M., Williams, J., Lovestone, S. & Powell, J. F., 2005, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 138B, 1, p. 41 - 42 2 p.

    Research output: Contribution to journalMeeting abstract

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