King's College London

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Research Outputs

  1. 2014
  2. Associations between intimate partner violence and termination of pregnancy: a systematic review and meta-analysis

    Hall, M., Chappell, L. C., Parnell, B. L., Seed, P. T. & Bewley, S., 7 Jan 2014, In : PL o S Medicine. 11, 1, 25 p., e1001581.

    Research output: Contribution to journalReview article

  3. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

    Killick, R., Ribe, E. M., Al-Shawi, R., Malik, B., Hooper, C., Fernandes, C., Dobson, R., Nolan, P. M., Lourdusamy, A., Furney, S., Lin, K., Breen, G., Wroe, R., To, A. W. M., Leroy, K., Causevic, M., Usardi, A., Robinson, M., Noble, W., Williamson, R. & 9 others, Lunnon, K., Kellie, S., Reynolds, C. H., Bazenet, C., Hodges, A., Brion, J-P., Stephenson, J., Paul Simons, J. & Lovestone, S., 1 Jan 2014, In : Molecular Psychiatry. 19, 1, p. 88-98 11 p.

    Research output: Contribution to journalArticle

  4. Developing novel blood-based biomarkers for Alzheimer's disease

    Snyder, H. M., Carrillo, M. C., Grodstein, F., Henriksen, K., Jeromin, A., Lovestone, S., Mielke, M. M., O'Bryant, S., Sarasa, M., Sjøgren, M., Soares, H., Teeling, J., Trushina, E., Ward, M., West, T., Bain, L. J., Shineman, D. W., Weiner, M. & Fillit, H. M., Jan 2014, In : Alzheimer's & Dementia. 10, 1, p. 109-114 6 p.

    Research output: Contribution to journalArticle

  5. Does adding milk to tea delay gastric emptying?

    Hillyard, S., Cowman, S., Ramasundaram, R., Seed, P. T. & O'Sullivan, G., Jan 2014, In : British Journal of Anaesthesia. 112, 1, p. 66-71 6 p.

    Research output: Contribution to journalArticle

  6. Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort

    Aguilar, C., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Lovestone, S., Wahlund, L-O., Simmons, A., Westman, E. & AddNeuroMed Consortium, 2014, In : Frontiers in Aging Neuroscience. 6, 12 p., 145.

    Research output: Contribution to journalArticle

  7. Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease in Two Independent Cohorts

    Khan, W. W., Westman, E., Jones, N., Wahlund, L-O., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Spenger, C., Lovestone, S., Muehlboeck, J-S., Simmons, A. & for the AddNeuroMed consortium and for the Alzheimer’s Disease Neuroimaging Initiative, 2014, In : Brain topography. 14 p.

    Research output: Contribution to journalArticle

  8. CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: A prospective AddNeuroMed study

    Paajanen, T., Hänninen, T., Tunnard, C., Hallikainen, M., Mecocci, P., Sobow, T., Tsolaki, M., Vellas, B., Lovestone, S. & Soininen, H., 2014, In : JOURNAL OF ALZHEIMERS DISEASE. 39, 3, p. 679-690 12 p.

    Research output: Contribution to journalArticle

  9. Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study

    Kiddle, S. J., Sattlecker, M., Proitsi, P., Simmons, A., Westman, E., Bazenet, C., Nelson, S. K., Williams, S., Hodges, A., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Newhouse, S., Lovestone, S. & Dobson, R. J. B., 2014, In : JOURNAL OF ALZHEIMERS DISEASE. 38, 3, p. 515-531 17 p., N/A.

    Research output: Contribution to journalLiterature review

  10. Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis

    Bramham, K., Parnell, B., Nelson-Piercy, C., Seed, P. T., Poston, L. & Chappell, L. C., 2014, In : BMJ. 348, 7954, 20 p., g2301.

    Research output: Contribution to journalArticle

  11. Clopidogrel as prophylactic treatment for migraine: A pilot randomised, controlled study

    Chambers, J. B., Seed, P. T. & Ridsdale, L., 2014, In : Cephalalgia. 34, 14, p. 1163-1168 6 p.

    Research output: Contribution to journalArticle

  12. Developing a new model for patient recruitment in mental health services: A cohort study using Electronic Health Records

    Callard, F., Broadbent, M., Denis, M., Hotopf, M., Soncul, M., Wykes, T., Lovestone, S. & Stewart, R., 2014, In : BMJ open. 4, 12, e005654.

    Research output: Contribution to journalArticle

  13. Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness

    Lebedev, A. V., Westman, E., Van Westen, G. J. P., Kramberger, M. G., Lundervold, A., Aarsland, D., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S. & Simmons, A., 2014, In : NeuroImage: Clinical. 6, p. 115-125 11 p.

    Research output: Contribution to journalArticle

  14. 2013
  15. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Lambert, J-C., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., DeStefano, A. L., Bis, J. C., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Ikram, M. A., Zelenika, D., Vardarajan, B. N. & 34 others, Kamatani, Y., Lin, C-F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M-T., Choi, S-H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Lovestone, S., Proitsi, P., Powell, J. F., EADI, GERAD, ADGC & CHARGE, Dec 2013, In : Nature Genetics. 45, 12, p. 1452-1458 7 p., N/A.

    Research output: Contribution to journalArticle

  16. Exploration and confirmation of factors associated with uncomplicated pregnancy in nulliparous women: prospective cohort study

    Chappell, L. C., Seed, P. T., Myers, J., Taylor, R. S., Kenny, L. C., Dekker, G. A., Walker, J. J., McCowan, L. M. E., North, R. A. & Poston, L., 21 Nov 2013, In : BMJ. 347, 12 p., f6398.

    Research output: Contribution to journalArticle

  17. Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia

    Chappell, L., Duckworth, S., Seed, P., Griffin, M., Myers, J., Mackillop, L., Simons, N., Waugh, J., Anumba, D., Kenny, L. C., Redman, C. W. G. & Shennan, A., Nov 2013, In : Circulation (Baltimore). 128, 19, p. 2121-2131 10 p.

    Research output: Contribution to journalArticle

  18. Association of migraine aura with patent foramen ovale and atrial septal aneurysms

    Chambers, J., Seed, P. T. & Ridsdale, L., 9 Oct 2013, In : International Journal of Cardiology. 168, 4, p. 3949-3953 5 p.

    Research output: Contribution to journalArticle

  19. Duplex ultrasound volumetric flow analysis before and after hemodialysis in patients with brachio-cephalic fistulae

    Chowdhury, S., Goss, D., Mistry, H., Stephenson, M. A., Seed, P., Deane, C. & Valenti, D., 1 Oct 2013, In : The journal of vascular access. 14, 4, p. 342-347 6 p.

    Research output: Contribution to journalArticle

  20. Correction: Harnessing Clinical Psychiatric Data with an Electronic Assessment Tool (OPCRIT+): The Utility of Symptom Dimensions

    Brittain, P. J., Lobo, S. E. M., Rucker, J., Amarasinghe, M., Anilkumar, A. P. P., Baggaley, M., Banerjee, P., Bearn, J., Broadbent, M., Butler, M., Campbell, C. D., Cleare, A. J., Dratcu, L., Frangou, S., Gaughran, F., Goldin, M., Henke, A., Kern, N., Krayem, A., Mufti, F. & 18 others, McIvor, R., Needham-Bennett, H., Newman, S., Olajide, D., O'Flynn, D., Rao, R., Rehman, I. U., Seneviratne, G., Stahl, D., Suleman, S., Treasure, J., Tully, J., Veale, D., Stewart, R., McGuffin, P., Lovestone, S., Hotopf, M. & Schumann, G., 10 Sep 2013, In : PLoS ONE. 8, 9

    Research output: Contribution to journalArticle

  21. Blood-based biomarker discovery using aptamer capture (SOMAscan) platform technology

    Sattlecker, M., Pritchard, M., Proitsi, P., Kiddle, S., Newhouse, S., Simmons, A., Johnston, C., Leung, R., Dixit, A., Bazenet, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Stewart, A., Williams, S. C. R., Nelson, S., Lovestone, S. H. & Dobson, R. J. B., 1 Jul 2013, In : Alzheimer's Dementia: The Journal of the Alzheimer's Association. 9, 4, p. P861 1 p.

    Research output: Contribution to journalArticle

  22. The importance of tau phosphorylation for neurodegenerative diseases

    Noble, W., Hanger, D., Miller, C. & Lovestone, S., 1 Jul 2013, In : Frontiers in Neurology. 4, 83

    Research output: Contribution to journalBook/Film/Article review

  23. Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

    Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J. & Saykin, A. J., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 739 1 p.

    Research output: Contribution to journalArticle

  24. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

    Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 18 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J., Saykin, A. J., MIRAGE Study, AddNeuroMed Consortium, Indiana Memory Aging Study & ADNI, Jul 2013, In : Molecular Psychiatry. 18, 7, p. 781-787 7 p., N/A.

    Research output: Contribution to journalArticle

  25. Inflammatory Proteins in Plasma Are Associated with Severity of Alzheimer's Disease

    Leung, R., Proitsi, P., Simmons, A., Lunnon, K., Guentert, A., Kronenberg, D., Pritchard, M., Tsolaki, M., Mecocci, P., Kloszewska, I., Vellas, B., Soininen, H., Wahlund, L-O. & Lovestone, S., 10 Jun 2013, In : PL o S One . 8, 6, 10 p., e64971.

    Research output: Contribution to journalArticle

  26. Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol

    Mangialasche, F., Westman, E., Kivipelto, M., Muehlboeck, J. -S., Cecchetti, R., Baglioni, M., Tarducci, R., Gobbi, G., Floridi, P., Soininen, H., Kloszewska, I., Tsolaki, M., Vellas, B., Spenger, C., Lovestone, S., Wahlund, L. -O., Simmons, A., Mecocci, P. & AddNeuroMed Consortium, Jun 2013, In : Journal of Internal Medicine. 273, 6, p. 602-621 20 p.

    Research output: Contribution to journalArticle

  27. Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment

    Aguilar, C., Westman, E., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Lovestone, S., Spenger, C., Simmons, A. & Wahlund, L-O., 30 May 2013, In : Psychiatry Research. Neuroimaging. 212, 2, p. 89-98 10 p., N/A.

    Research output: Contribution to journalArticle

  28. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimertextquotesingles disease

    Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C. & 67 others, Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Schürmann, B., Heun, R., Bussche, H. V. D., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., Deyn, P. P. D., Broeckhoven, C. V., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K-H., Klopp, N., Wichmann, H-E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Holmans, P. A., OtextquotesingleDonovan, M., Owen, M. J. & Williams, J., 1 May 2013, In : Nature Genetics. 45, 6, p. 712-712 1 p.

    Research output: Contribution to journalArticle

  29. An MRI-based index to measure the severity of Alzheimer's disease-like structural pattern in subjects with mild cognitive impairment

    Spulber, G., Simmons, A., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Spenger, C., Lovestone, S., Wahlund, L-O., Westman, E., AddNeuroMed Consortium & Alzheimer Dis Neuroimaging Initiat, Apr 2013, In : Journal of Internal Medicine. 273, 4, p. 396-409 14 p.

    Research output: Contribution to journalArticle

  30. The Public Health Impact score: a new measure of public health effectiveness for general practices in England

    Ashworth, M., Schofield, P., Doran, T., Cookson, R., Sutton, M., Seed, P. T., Howe, A. & Fleetcroft, R., Apr 2013, In : British Journal of General Practice. 63, 609, p. e291-e299 9 p.

    Research output: Contribution to journalArticle

  31. Harnessing clinical psychiatric data with an electronic assessment tool (OPCRIT+): the utility of symptom dimensions

    Brittain, P. J., Lobo, S. E. M., Rucker, J., Amarasinghe, M., Anilkumar, A. P. P., Baggaley, M., Banerjee, P., Bearn, J., Broadbent, M., Butler, M., Campbell, C. D., Cleare, A. J., Dratcu, L., Frangou, S., Gaughran, F., Goldin, M., Henke, A., Kern, N., Krayem, A., Mufti, F. & 18 others, McIvor, R., Needham-Bennett, H., Newman, S., Olajide, D., O'Flynn, D., Rao, R., Rehman, I., Seneviratne, G., Stahl, D., Suleman, S., Treasure, J., Tully, J., Veale, D., Stewart, R., McGuffin, P., Lovestone, S., Hotopf, M. & Schumann, G., 8 Mar 2013, In : PLoS ONE. 8, 3, 8 p., e58790.

    Research output: Contribution to journalArticle

  32. Alzheimer Risk Varia2nt CLU and Brain Function During Aging

    Thambisetty, M., Beason-Held, L. L., An, Y., Kraut, M., Nalls, M., Hernandez, D. G., Singleton, A. B., Zonderman, A. B., Ferrucci, L., Lovestone, S. & Resnick, S. M., 1 Mar 2013, In : Biological psychiatry. 73, 5, p. 399-405 7 p., N/A.

    Research output: Contribution to journalArticle

  33. Harnessing Clinical Psychiatric Data with an Electronic Assessment Tool (OPCRIT+): The Utility of Symptom Dimensions

    Brittain, P. J., Lobo, S. E. M., Rucker, J., Amarasinghe, M., Anilkumar, A. P. P., Baggaley, M., Banerjee, P., Bearn, J., Broadbent, M., Butler, M., Campbell, C. D., Cleare, A. J., Dratcu, L., Frangou, S., Gaughran, F., Goldin, M., Henke, A., Kern, N., Krayem, A., Mufti, F. & 18 others, McIvor, R., Needham-Bennett, H., Newman, S., Olajide, D., O'Flynn, D., Rao, R., Rehman, I. U., Seneviratne, G., Stahl, D., Suleman, S., Treasure, J., Tully, J., Veale, D., Stewart, R., McGuffin, P., Lovestone, S., Hotopf, M. & Schumann, G., 1 Mar 2013, In : PloS one. 8, 3, p. e58790

    Research output: Contribution to journalArticle

  34. Development and validation of a measure of health literacy in the UK: the newest vital sign

    Rowlands, G., Khazaezadeh, N., Oteng-Ntim, E., Seed, P., Barr, S. & Weiss, B. D., 7 Feb 2013, In : BMC Public Health. 13, 9 p., 116.

    Research output: Contribution to journalArticle

  35. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH

    Killick, R., Hughes, T. R., Morgan, B. P. & Lovestone, S., 15 Jan 2013, In : Neuroscience Letters. 533, p. 96-99 4 p.

    Research output: Contribution to journalArticle

  36. Impact of Obesity on Pregnancy Outcome in Different Ethnic Groups: Calculating Population Attributable Fractions

    Oteng-Ntim, E., Kopeika, J., Seed, P., Wandiembe, S. & Doyle, P., 14 Jan 2013, In : PL o S One . 8, 1, 7 p., e53749.

    Research output: Contribution to journalArticle

  37. The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder

    Smith, B. N., Newhouse, S., Shatunov, A., Vance, C., Topp, S., Johnson, L., Miller, J., Lee, Y., Troakes, C., Scott, K. M., Jones, A., Gray, I., Wright, J., Hortobágyi, T., Al-Sarraj, S., Rogelj, B., Powell, J., Lupton, M., Lovestone, S., Sapp, P. C. & 26 others, Weber, M., Nestor, P. J., Schelhaas, H. J., Asbroek, A. A. T., Silani, V., Gellera, C., Taroni, F., Ticozzi, N., Van den Berg, L., Veldink, J., Van Damme, P., Robberecht, W., Shaw, P. J., Kirby, J., Pall, H., Morrison, K. E., Morris, A., de Belleroche, J., Vianney de Jong, J. M. B., Baas, F., Andersen, P. M., Landers, J., Brown, R. H., Weale, M. E., Al-Chalabi, A. & Shaw, C. E., Jan 2013, In : European Journal of Human Genetics. 21, 1, p. 102-108 7 p., N/A.

    Research output: Contribution to journalArticle

  38. A Blood Gene Expression Marker of Early Alzheimer's Disease

    Lunnon, K., Sattlecker, M., Furney, S. J., Coppola, G., Simmons, A., Proitsi, P., Lupton, M. K., Lourdusamy, A., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Geschwind, D., Lovestone, S., Dobson, R., Hodges, A. & AddNeuroMed Consortium, 2013, In : JOURNAL OF ALZHEIMERS DISEASE. 33, 3, p. 737-753 17 p.

    Research output: Contribution to journalArticle

  39. Candidate Blood Proteome Markers of Alzheimer’s Disease Onset and Progression: A Systematic Review and Replication Study

    Kiddle, S., Sattlecker, M., Proitsi, P., Simmons, A., Westman, E., Bazenet, C., Nelson, S., Williams, S., Hodges, A., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Newhouse, S., Lovestone, S. & Dobson, R., 2013, In : JOURNAL OF ALZHEIMERS DISEASE. N/A, N/A, p. N/A N/A.

    Research output: Contribution to journalArticle

  40. Entorhinal Cortex Thickness Predicts Cognitive Decline in Alzheimer's Disease

    Velayudhan, L., Proitsi, P., Westman, E., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Spenger, C., Hodges, A., Powell, J., Lovestone, S., Simmons, A. & AddNeuroMed Consortium, 2013, In : JOURNAL OF ALZHEIMERS DISEASE. 33, 3, p. 755-766 12 p.

    Research output: Contribution to journalArticle

  41. Trait, State, and Mechanism: Looking Back, Looking Forward, and Understanding Why

    Lovestone, S., 2013, In : JOURNAL OF ALZHEIMERS DISEASE. 33, s1, p. S23-S33 11 p., N/A.

    Research output: Contribution to journalLiterature review

  42. 2012
  43. Limited Relationship between Cervico-Vaginal Fluid Cytokine Profiles and Cervical Shortening in Women at High Risk of Spontaneous Preterm Birth

    Chandiramani, M., Seed, P. T., Orsi, N. M., Ekbote, U. V., Bennett, P. R., Shennan, A. H. & Tribe, R. M., 26 Dec 2012, In : PL o S One . 7, 12, p. N/A 11 p., e52412.

    Research output: Contribution to journalArticle

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