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Research Outputs

  1. 2020
  2. Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants

    Persyn, E., Hanscombe, K. B., Howson, J. M. M., Lewis, C. M., Traylor, M. & Markus, H. S., 1 Dec 2020, In : Nature Communications. 11, 1, 2175.

    Research output: Contribution to journalArticle

  3. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In : Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticle

  4. The UK pregnancies better eating and activity trial (UPBEAT); pregnancy outcomes and health behaviours by obesity class

    Peacock, L., Seed, P. T., Dalrymple, K. V., White, S. L., Poston, L. & Flynn, A. C., Jul 2020, In : International Journal of Environmental Research and Public Health. 17, 13, p. 1-17 17 p., 4712.

    Research output: Contribution to journalArticle

  5. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 1 Jun 2020, In : HYPERTENSION IN PREGNANCY. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  6. Genetic stratification of depression in UK Biobank

    Howard, D., Folkersen, L., Coleman, J., Adams, M., Glanville, K., Werge, T., Hagenaars, S., Han, B., Porteous, D., Campbell, A., Clarke, T-K., Breen, G., Sullivan, P. F., Wray, N. R., Lewis, C. & McIntosh, A., 24 May 2020, In : Translational psychiatry.

    Research output: Contribution to journalArticle

  7. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In : Thorax.

    Research output: Contribution to journalArticle

  8. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In : Trials. 21, 1, p. 347

    Research output: Contribution to journalArticle

  9. Dysregulated Fc gamma receptor–mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis

    AddNeuroMed consortium and the Alzheimer's Disease Neuroimaging Initiative, Apr 2020, In : Neurobiology of Aging. 88, p. 24-32 9 p.

    Research output: Contribution to journalArticle

  10. Johannesburg Cancer Study (JCS): contribution to knowledge and opportunities arising from 20 years of data collection in an African setting

    Chen, W. C., Singh, E., Muchengeti, M., Bradshaw, D., Mathew, C. G., Babb de Villiers, C., Lewis, C. M., Waterboer, T., Newton, R. & Sitas, F., Apr 2020, In : Cancer Epidemiology. 65, 101701.

    Research output: Contribution to journalArticle

  11. Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

    Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K., Breen, G., Air, T. M., Andlauer, T. M. F., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., de Geus, E. J. C. & 34 others, Grabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Lucae, S., Magnusson., P. K. E., McGuffin, P., McIntosh, A., Milaneschi, Y., Lewis, C. M., Mostafavi, S., Muller-Myhsok, B., Pedersen, N. L., Penninx, B. W., Potash, J. B., Preisig, M., Ripke, S., Shi, J., Shyn, S. I., Smoller, J. W., Streit, F., Sullivan, P. F., Tiemeier, H., Uher, R., der Auwera, S. V., Weissman, M. M., O'Reilly, P. F. & Lewis, C. M., 1 Mar 2020, In : Biological psychiatry. 87, 5, p. 419-430 12 p.

    Research output: Contribution to journalArticle

  12. A polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genotyping

    Fabbri, C., Kasper, S., Kautzky, A., Zohar, J., Souery, D., Montgomery, S., Albani, D., Forloni, G., Ferentinos, P., Rujescu, D., Mendlewicz, J., Uher, R., Lewis, C. M. & Serretti, A., 3 Feb 2020, In : Translational psychiatry. 10, 1, 50.

    Research output: Contribution to journalArticle

  13. IQ score gains over 65 years worldwide: Cross-temporal meta-analysis datasets

    Wongupparaj, P., Kumari, V. & Morris, R. G., 1 Feb 2020, In : Data in Brief. 28, 104884.

    Research output: Contribution to journalArticle

  14. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In : Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  15. Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

    Coleman, J. R. I., Peyrot, W. J., Purves, K., Davis, K. A. S., Rayner, C., Choi, S. W., Huebel, C., Gaspar, H. A., Kan, C., der Auwera, S. V., Adams, M. J., Lyall, D., Choi, K. W., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dunn, E. C., Vassos, E., Danese, A., Maughan, B., Grabe, H. J., Lewis, C. M. & 7 others, O'Reilly, P. F., McIntosh, A. M., Smith, D. J., Wray, N. R., Hotopf, M., Eley, T. C. & Breen, G., 23 Jan 2020, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  16. The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

    Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2020, In : Biological psychiatry.

    Research output: Contribution to journalArticle

  17. 2019
  18. Lifestyle information and commercial weight management groups to support maternal postnatal weight management and positive lifestyle behaviour: the SWAN feasibility randomised controlled trial

    Bick, D., Taylor, C., Bhavnani, V., Healey, A., Seed, P., Roberts, S., Zasada, M., Avery, A., Craig, V., Khazaezadah, N., McMullen, S., O'Connor, S., Oki, B., Oteng Ntim, E., Poston, L. & Ussher, M., 5 Dec 2019, In : BJOG. 27 p.

    Research output: Contribution to journalArticle

  19. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

    Borges Manna, L., Ovadia, C., Lövgren-Sandblom, A., Chambers, J., Begum, S., Seed, P., Walker, I., Chappell, L. C., Marschall, H-U. & Williamson, C., 1 Dec 2019, In : BJOG. 126, 13, p. 1633-1640 8 p.

    Research output: Contribution to journalArticle

  20. Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models

    Paul, R., Andlauer, T. F. M., Czamara, D., Hoehn, D., Lucae, S., Pütz, B., Lewis, C. M., Uher, R., Müller-Myhsok, B., Ising, M. & Sämann, P. G., 1 Dec 2019, In : Translational psychiatry. 9, 1, 187.

    Research output: Contribution to journalArticle

  21. Neural responses to criticism and praise vary with schizotypy and perceived emotional support

    Premkumar, P., Santo, M. G. E., Onwumere, J., Schürmann, M., Kumari, V., Blanco, S., Baker, J. & Kuipers, E., 1 Nov 2019, In : International journal of psychophysiology. 145, p. 109-118 10 p.

    Research output: Contribution to journalArticle

  22. Genetic architecture of subcortical brain structures in 38,851 individuals

    Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 30 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Hagenaars, S. P., Walton, E., Jia, T., Macare, C., Simmons, A. & Schumann, G., Nov 2019, In : Nature Genetics. 51, 11, p. 1624-1636 13 p.

    Research output: Contribution to journalArticle

  23. Pregnancy-related Acute Kidney Injury in pre-eclampsia: risk factors and renal outcomes

    Conti-Ramsden, F. I., Nathan, H. L., De Greeff, A., Hall, D. R., Seed, P. T., Chappell, L. C., Shennan, A. H. & Bramham, K., Nov 2019, In : Hypertension. 74, 5, p. 1144–1151 8 p.

    Research output: Contribution to journalArticle

  24. Relationships of maternal body mass index and plasma biomarkers with childhood body mass index and adiposity at 6 years: The Children of SCOPE study

    on behalf of SCOPE consortium, 1 Oct 2019, In : Pediatric Obesity. 14, 10, 12 p., e12537.

    Research output: Contribution to journalArticle

  25. Genetic variation of the endocannabinoids system and risk of first episode psychosis

    Quattrone, D., Vassos, E., Richards, A., Reininghaus, U., Sham, P., O'Donovan, M. C., Lewis, C. M., Murray, R. M. & Di Forti, M., 24 Sep 2019, Genetic variation of the endocannabinoids system and risk of first episode psychosis.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  26. Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals: Genomic Precision Medicine May Dispense With Ethnicity

    Iniesta, R., Campbell, D., Venturini, C., Faconti, L., Singh, S., Irvin, M. R., Cooper-DeHoff, R. M., Johnson, J. A., Turner, S. T., Arnett, D. K., Weale, M. E., Warren, H., Munroe, P. B., Cruickshank, K., Padmanabhan, S., Lewis, C. & Chowienczyk, P., 1 Sep 2019, In : Hypertension (Dallas, Tex. : 1979). 74, 3, p. 614-622 9 p.

    Research output: Contribution to journalArticle

  27. Prevalence of Advanced Liver Fibrosis in Patients With Severe Psoriasis

    Maybury, C. M., Porter, H. F., Kloczko, E., Duckworth, M., Cotton, A., Thornberry, K., Dew, T., Crook, M., Natas, S., Miquel, R., Lewis, C. M., Wong, T., Smith, C. H. & Barker, J. N., 1 Sep 2019, In : JAMA dermatology. 155, 9, p. 1028-1032 5 p.

    Research output: Contribution to journalArticle

  28. Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., Anjorin, A., Corvin, A., Sanders, A. R., Forstner, A. J., Reif, A., Koller, A. C., Świątkowska, B., Baune, B. T. & 95 others, Müller-Myhsok, B., Penninx, B. W. J. H., Pato, C. N., Zai, C. C., Rujescu, D., Hougaard, D. M., Quested, D., Levinson, D. F., Binder, E. B., Byrne, E. M., Agerbo, E., Streit, F., Mayoral, F., Bellivier, F., Degenhardt, F., Breen, G. D., Morken, G., Turecki, G., Rouleau, G., Grabe, H. J., Volzke, H., Jones, I., Giegling, I., Agartz, I., Melle, I., Lawrence, J., Walters, J. T. R., Strohmaier, J., Shi, J., Hauser, J., Biernacka, J. M., Vincent, J. B., Kelsoe, J., Strauss, J. S., Lissowska, J., Pimm, J., Smoller, J. W., Guzman-Parra, J., Berger, K., Scott, L. J., Jones, L. A., Azevedo, M. H., Trzaskowski, M., Kogevinas, M., Rietschel, M., Boks, M. P., Ising, M., Grigoroiu-Serbanescu, M., Hamshere, M. L., Leboyer, M., Frye, M. A., Alda, M., Nordentoft, M., Boehnke, M., O'Donovan, M. C., Owen, M. J., Pato, M. T., Renteria, M. E., Wray, N. R., Bass, N., Craddock, N., Smeland, O. B., Andreassen, O. A., Mors, O., Gejman, P. V., Sklar, P., McGrath, P. J., Hoffmann, P., McGuffin, P., Lee, P. H., Mortensen, P. B., Kahn, R. S., Ophoff, R. A., Adolfsson, R., Van der Auwera Affiliations, S., Djurovic, S., Kloiber, S., Heilmann-Heimbach, S., Jamain, S., Hamilton, S. P., Mcelroy, S. L., Lucae, S., Cichon, S., Schulze, T. G., Hansen, T., Werge, T., Air, T. M., Nimgaonkar, V., Appadurai, V., Cahn, W., Milaneschi, Y., Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C. M., 1 Aug 2019, In : The American Journal of Psychiatry. 176, 8, p. 651-660 10 p.

    Research output: Contribution to journalArticle

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