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  1. 2020
  2. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In : Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticle

  3. Consumption of Stilbenes and Flavonoids is Linked to Reduced Risk of Obesity Independently of Fiber Intake

    Mompeo, O., Spector, T. D., Matey Hernandez, M., Le Roy, C., Istas, G., Le Sayec, M., Mangino, M., Jennings, A., Rodriguez-Mateos, A., Valdes, A. M. & Menni, C., 23 Jun 2020, In : Nutrients. 12, 6

    Research output: Contribution to journalArticle

  4. Serial blood cytokine and chemokine mRNA and microRNA over 48 h are insult specific in a piglet model of inflammation-sensitized hypoxia-ischaemia

    Lingam, I., Avdic-Belltheus, A., Meehan, C., Martinello, K., Ragab, S., Peebles, D., Barkhuizen, M., Tann, C. J., Tachtsidis, I., Wolfs, T. G. A. M., Hagberg, H., Klein, N., Fleiss, B., Gressens, P., Golay, X., Kramer, B. W. & Robertson, N. J., 10 Jun 2020, In : Pediatric Research.

    Research output: Contribution to journalArticle

  5. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 1 Jun 2020, In : HYPERTENSION IN PREGNANCY. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  6. Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, 27 May 2020, In : Nature Communications. 11, 1, 2539.

    Research output: Contribution to journalArticle

  7. Real-time tracking of self-reported symptoms to predict potential COVID-19

    Menni, C., Valdes, A. M., Freidin, M. B., Sudre, C. H., Nguyen, L. H., Drew, D. A., Ganesh, S., Varsavsky, T., Cardoso, M. J., El-Sayed Moustafa, J. S., Visconti, A., Hysi, P., Bowyer, R. C. E., Mangino, M., Falchi, M., Wolf, J., Ourselin, S., Chan, A. T., Steves, C. J. & Spector, T. D., 11 May 2020, In : Nature Medicine.

    Research output: Contribution to journalArticle

  8. Rapid implementation of mobile technology for real-time epidemiology of COVID-19

    COPE Consortium, Drew, D. A., Nguyen, L. H., Steves, C. J., Menni, C., Freydin, M., Varsavsky, T., Sudre, C. H., Cardoso, M. J., Ourselin, S., Wolf, J., Spector, T. D. & Chan, A. T., 5 May 2020, In : Science.

    Research output: Contribution to journalArticle

  9. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In : Thorax.

    Research output: Contribution to journalArticle

  10. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In : Trials. 21, 1, p. 347

    Research output: Contribution to journalArticle

  11. Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly

    Journiac, N., Gilabert-Juan, J., Cipriani, S., Benit, P., Liu, X., Jacquier, S., Faivre, V., Delahaye-Duriez, A., Csaba, Z., Hourcade, T., Melinte, E., Lebon, S., Violle-Poirsier, C., Oury, J-F., Adle-Biassette, H., Wang, Z-Q., Mani, S., Rustin, P., Gressens, P. & Nardelli, J., 14 Apr 2020, In : Cell Reports. 31, 2, 107506.

    Research output: Contribution to journalArticle

  12. Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

    Nag, A., Kurushima, Y., Bowyer, R. C. E., Wells, P. M., Weiss, S., Pietzner, M., Kocher, T., Raffler, J., Völker, U., Mangino, M., Spector, T. D., Milburn, M. V., Kastenmüller, G., Mohney, R. P., Suhre, K., Menni, C. & Steves, C. J., 27 Mar 2020, In : Human Molecular Genetics. 29, 5, p. 864-875 12 p., ddz308.

    Research output: Contribution to journalArticle

  13. Differences between race and sex in measures of hip morphology: a population-based comparative study

    Edwards, K., Leyland, K. M., Sanchez-Santos, M. T., Arden, C. P., Spector, T. D., Nelson, A. E., Jordan, J. M., Nevitt, M., Hunter, D. J. & Arden, N. K., 1 Feb 2020, In : Osteoarthritis and Cartilage. 28, 2, p. 189-200 12 p.

    Research output: Contribution to journalArticle

  14. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In : Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  15. The incidence and characteristics of accelerated knee osteoarthritis among women: The Chingford cohort

    Driban, J. B., Bannuru, R. R., Eaton, C. B., Spector, T. D., Hart, D. J., McAlindon, T. E., Lu, B., Lo, G. H. & Arden, N. K., 31 Jan 2020, In : BMC MUSCULOSKELETAL DISORDERS. 21, 1, 60.

    Research output: Contribution to journalArticle

  16. An unsupervised learning approach to identify novel signatures of health and disease from multimodal data

    Shomorony, I., Cirulli, E. T., Huang, L., Napier, L. A., Heister, R. R., Hicks, M., Cohen, I. V., Yu, H. C., Swisher, C. L., Schenker-Ahmed, N. M., Li, W., Nelson, K. E., Brar, P., Kahn, A. M., Spector, T. D., Caskey, C. T., Venter, J. C., Karow, D. S., Kirkness, E. F. & Shah, N., 10 Jan 2020, In : Genome medicine. 12, 1, 1 p., 7.

    Research output: Contribution to journalArticle

  17. 32P-Postlabeling analysis of DNA adducts

    Phillips, D. H. & Arlt, V. M., 1 Jan 2020, Methods in Molecular Biology. Humana Press Inc, p. 291-302 12 p. (Methods in Molecular Biology; vol. 2102).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  18. Predicting Incident Radiographic Knee Osteoarthritis in Middle-Aged Women Within Four Years: The Importance of Knee-Level Prognostic Factors

    Garriga, C., Sánchez-Santos, M. T., Judge, A., Hart, D., Spector, T., Cooper, C. & Arden, N. K., 1 Jan 2020, In : Arthritis Care and Research. 72, 1, p. 88-97 10 p.

    Research output: Contribution to journalArticle

  19. Red Wine Consumption Associated With Increased Gut Microbiota α-Diversity in 3 Independent Cohorts

    Le Roy, C. I., Wells, P. M., Si, J., Raes, J., Bell, J. T. & Spector, T. D., Jan 2020, In : Gastroenterology. 158, 1, p. 270-272.e2

    Research output: Contribution to journalArticle

  20. 2019
  21. HLA Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut Microbiome

    Asquith, M., Sternes, P. R., Costello, M. E., Karstens, L., Diamond, S., Martin, T. M., Li, Z., Marshall, M. S., Spector, T. D., le Cao, K. A., Rosenbaum, J. T. & Brown, M. A., 12 Dec 2019, In : Arthritis and Rheumatology. 71, 10, p. 1642-1650 9 p.

    Research output: Contribution to journalArticle

  22. Lifestyle information and commercial weight management groups to support maternal postnatal weight management and positive lifestyle behaviour: the SWAN feasibility randomised controlled trial

    Bick, D., Taylor, C., Bhavnani, V., Healey, A., Seed, P., Roberts, S., Zasada, M., Avery, A., Craig, V., Khazaezadah, N., McMullen, S., O'Connor, S., Oki, B., Oteng Ntim, E., Poston, L. & Ussher, M., 5 Dec 2019, In : BJOG. 27 p.

    Research output: Contribution to journalArticle

  23. A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

    Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmüller, G., Boyd, A., Zierer, J., van den Akker, E. B., Ala-Korpela, M., Amin, N., Demirkan, A., Ghanbari, M., van Heemst, D., Ikram, M. A., van Klinken, J. B., Mooijaart, S. P., Peters, A., Salomaa, V., Sattar, N. & 15 others, Spector, T. D., Tiemeier, H., Verhoeven, A., Waldenberger, M., Würtz, P., Davey Smith, G., Metspalu, A., Perola, M., Menni, C., Geleijnse, J. M., Drenos, F., Beekman, M., Jukema, J. W., van Duijn, C. M. & Slagboom, P. E., 1 Dec 2019, In : Nature Communications. 10, 1, 3346.

    Research output: Contribution to journalArticle

  24. Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy

    Martinello, K. A., Meehan, C., Avdic-Belltheus, A., Lingam, I., Ragab, S., Hristova, M., Tann, C. J., Peebles, D., Hagberg, H., Wolfs, T. G. A. M., Klein, N., Tachtsidis, I., Golay, X., Kramer, B. W., Fleiss, B., Gressens, P. & Robertson, N. J., 1 Dec 2019, In : Scientific Reports. 9, 1, 10184.

    Research output: Contribution to journalArticle

  25. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

    Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P. C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S. J. & 37 others, Bressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M. F., Rotter, J. I., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D. I., Bell, J. T., Demirkan, A. & van Duijn, C. M., 1 Dec 2019, In : Nature Communications. 10, 1, 2581.

    Research output: Contribution to journalArticle

  26. Effect of diet on the gut microbiota: Rethinking intervention duration

    Leeming, E. R., Johnson, A. J., Spector, T. D. & Roy, C. I. L., 1 Dec 2019, In : Nutrients. 11, 12, 2862.

    Research output: Contribution to journalReview article

  27. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

    Borges Manna, L., Ovadia, C., Lövgren-Sandblom, A., Chambers, J., Begum, S., Seed, P., Walker, I., Chappell, L. C., Marschall, H-U. & Williamson, C., 1 Dec 2019, In : BJOG. 126, 13, p. 1633-1640 8 p.

    Research output: Contribution to journalArticle

  28. Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

    van der Spek, A., Broer, L., Draisma, H. H. M., Pool, R., Albrecht, E., Beekman, M., Mangino, M., Raag, M., Nyholt, D. R., Dharuri, H. K., Codd, V., Amin, N., de Geus, E. J. C., Deelen, J., Demirkan, A., Yet, I., Fischer, K., Haller, T., Henders, A. K., Isaacs, A. & 19 others, Medland, S. E., Montgomery, G. W., Mooijaart, S. P., Strauch, K., Suchiman, H. E. D., Vaarhorst, A. A. M., van Heemst, D., Wang-Sattler, R., Whitfield, J. B., Willemsen, G., Wright, M. J., Martin, N. G., Samani, N. J., Metspalu, A., Eline Slagboom, P., Spector, T. D., Boomsma, D. I., van Duijn, C. M. & Gieger, C., 1 Dec 2019, In : Scientific Reports. 9, 1, 11623.

    Research output: Contribution to journalArticle

  29. Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain

    Van Steenwinckel, J., Schang, A-L., Krishnan, M. L., Degos, V., Delahaye-Duriez, A., Bokobza, C., Csaba, Z., Verdonk, F., Montané, A., Sigaut, S., Hennebert, O., Lebon, S., Schwendimann, L., Le Charpentier, T., Hassan-Abdi, R., Ball, G., Aljabar, P., Saxena, A., Holloway, R. K., Birchmeier, W. & 12 others, Baud, O., Rowitch, D., Miron, V., Chretien, F., Leconte, C., Besson, V. C., Petretto, E. G., Edwards, A. D., Hagberg, H., Soussi-Yanicostas, N., Fleiss, B. & Gressens, P., Dec 2019, In : Brain : a journal of neurology. 142, 12, p. 3806–3833

    Research output: Contribution to journalArticle

  30. Novel genetic loci affecting facial shape variation in humans

    International Visible Trait Genetics (VisiGen) Consortium, 26 Nov 2019, In : eLife. 8, e49898.

    Research output: Contribution to journalArticle

  31. The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro

    Sborchia, M., De Prez, E. G., Antoine, M. H., Bienfait, L., Indra, R., Valbuena, G., Phillips, D. H., Nortier, J. L., Stiborová, M., Keun, H. C. & Arlt, V. M., 1 Nov 2019, In : Archives of Toxicology. 93, 11, p. 3345-3366 22 p.

    Research output: Contribution to journalArticle

  32. Pregnancy-related Acute Kidney Injury in pre-eclampsia: risk factors and renal outcomes

    Conti-Ramsden, F. I., Nathan, H. L., De Greeff, A., Hall, D. R., Seed, P. T., Chappell, L. C., Shennan, A. H. & Bramham, K., Nov 2019, In : Hypertension. 74, 5, p. 1144–1151 8 p.

    Research output: Contribution to journalArticle

  33. Endoplasmic reticulum and Golgi stress in microcephaly

    Passemard, S., Perez, F., Gressens, P. & El Ghouzzi, V., 30 Oct 2019, In : Cell Stress. 3, 12, p. 369-384 16 p.

    Research output: Contribution to journalReview article

  34. Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns

    Menni, C., McCallum, L., Pietzner, M., Zierer, J. B., Aman, A., Suhre, K., Mohney, R., Mangino, M., Friedrich, N., Spector, T. D. & Padmanabhan, S., 21 Oct 2019, In : Scientific Reports. 9, 1, 8 p., 15088.

    Research output: Contribution to journalArticle

  35. Interplay between the human gut microbiome and host metabolism

    Visconti, A., Le Roy, C. I., Rosa, F., Martin, T. C., Mohney, R. P., Weizhong, L., de Rinaldis, E., Bell, J. T., Venter, J. C., Nelson, K. E., Spector, T. D. & Falchi, M., 3 Oct 2019, In : Nature Communications. 10, 1, 1 p., 4505.

    Research output: Contribution to journalArticle

  36. Relationships of maternal body mass index and plasma biomarkers with childhood body mass index and adiposity at 6 years: The Children of SCOPE study

    on behalf of SCOPE consortium, 1 Oct 2019, In : Pediatric Obesity. 14, 10, 12 p., e12537.

    Research output: Contribution to journalArticle

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