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Research Outputs

  1. 2020
  2. Acute heart failure

    Arrigo, M., Jessup, M., Mullens, W., Reza, N., Shah, A. M., Sliwa, K. & Mebazaa, A., 1 Dec 2020, In : Nature Reviews Disease Primers. 6, 1, 16.

    Research output: Contribution to journalReview article

  3. The effect of smoking on COVID-19 severity: a systematic review and meta-analysis

    Reddy, R. K., Charles, W. N., Sklavounos, A., Dutt, A., Seed, P. T. & Khajuria, A., 4 Aug 2020, In : Journal of Medical Virology.

    Research output: Contribution to journalArticle

  4. Visualisation tools for dependent peptide searches to support the exploration of in vitro protein modifications

    Preston, G., Yang, L., Phillips, D. & Maier, C., 8 Jul 2020, In : PloS one. 15(7):e0235263, 7, p. 15(7):e0235263 PXD013040.

    Research output: Contribution to journalArticle

  5. Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage

    Maqbool, A., Watt, N. T., Haywood, N., Viswambharan, H., Skromna, A., Makava, N., Visnagri, A., Shawer, H. M., Bridge, K., Muminov, S. K., Griffin, K., Beech, D. J., Wheatcroft, S. B., Porter, K. E., Simmons, K. J., Sukumar, P., Shah, A. M., Cubbon, R. M., Kearney, M. T. & Yuldasheva, N. Y., Jul 2020, In : American Journal of Physiology - Cell Physiology. 318, 1, p. C64-C74

    Research output: Contribution to journalArticle

  6. Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia

    Giblin, L., McCarthy, F. P., Gill, C., Seed, P. T., Bramham, K., Brockbank, A., Chappell, L. C. & Shennan, A. H., Jul 2020, In : Pregnancy Hypertension. 21, p. 35-37 3 p.

    Research output: Contribution to journalArticle

  7. The UK pregnancies better eating and activity trial (UPBEAT); pregnancy outcomes and health behaviours by obesity class

    Peacock, L., Seed, P. T., Dalrymple, K. V., White, S. L., Poston, L. & Flynn, A. C., Jul 2020, In : International Journal of Environmental Research and Public Health. 17, 13, p. 1-17 17 p., 4712.

    Research output: Contribution to journalArticle

  8. Serial blood cytokine and chemokine mRNA and microRNA over 48 h are insult specific in a piglet model of inflammation-sensitized hypoxia-ischaemia

    Lingam, I., Avdic-Belltheus, A., Meehan, C., Martinello, K., Ragab, S., Peebles, D., Barkhuizen, M., Tann, C. J., Tachtsidis, I., Wolfs, T. G. A. M., Hagberg, H., Klein, N., Fleiss, B., Gressens, P., Golay, X., Kramer, B. W. & Robertson, N. J., 10 Jun 2020, In : Pediatric Research.

    Research output: Contribution to journalArticle

  9. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort

    Bramham, K., Villa, P. M., Joslin, J. R., Laivuori, H., Hämäläinen, E., Kajantie, E., Räikkönen, K., Pesonen, A., Seed, P., Dalton, R. N., Turner, C., Wong, M., Von Dadelszen, P., Roberts, J. M., Poston, L. & Chappell, L. C., 1 Jun 2020, In : HYPERTENSION IN PREGNANCY. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  10. A Clinical Risk Score to Identify Patients with COVID-19 at High Risk of Critical Care Admission or Death: An Observational Cohort Study

    Galloway, J., Norton, S., Barker, R. D., Brookes, A., Carey, I., Clarke, B., Jina, R., Reid, C., Russell, M. D., Sneep, R., Sugarman, L., Williams, S., Yates, M., Teo, J. T., Shah, A. & Cantle, F., 18 May 2020, In : Journal of Infection. 81, 2, p. 282-288 7 p.

    Research output: Contribution to journalArticle

  11. Beyond Bacterial Killing: NADPH oxidase 2 is an immunomodulator

    Cellone Trevelin, S., Shah, A. & Lombardi, G., May 2020, In : Immunology Letters. 221, p. 39-48 10 p.

    Research output: Contribution to journalReview article

  12. Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

    Inparaj, S., Buckingham, M., Oakley, L., Seed, P. T., Lucas, S. & Oteng-Ntim, E., 28 Apr 2020, In : Thorax.

    Research output: Contribution to journalArticle

  13. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial

    Oakley, L. L., Awogbade, M., Brien, S., Briley, A., Chorozoglou, M., Drasar, E., Johns, J., Rhodes, E., Robinson, V., Seed, P., Sharif, J., Singh, C., Telfer, P., Thompson, H., Watt-Coote, I., Howard, J. & Oteng-Ntim, E., 20 Apr 2020, In : Trials. 21, 1, p. 347

    Research output: Contribution to journalArticle

  14. Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly

    Journiac, N., Gilabert-Juan, J., Cipriani, S., Benit, P., Liu, X., Jacquier, S., Faivre, V., Delahaye-Duriez, A., Csaba, Z., Hourcade, T., Melinte, E., Lebon, S., Violle-Poirsier, C., Oury, J-F., Adle-Biassette, H., Wang, Z-Q., Mani, S., Rustin, P., Gressens, P. & Nardelli, J., 14 Apr 2020, In : Cell Reports. 31, 2, 107506.

    Research output: Contribution to journalArticle

  15. Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)

    Kaura, A., Arnold, A. D., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Melikian, N., Lefroy, D. C. & 6 others, Francis, D. P., Shah, A. M., Kharbanda, R., Perera, D., Patel, R. S. & Mayet, J., 7 Apr 2020, In : Journal of the American Heart Association. 9, 7, p. e013684

    Research output: Contribution to journalArticle

  16. A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation

    Yang, J., Moraga, A., Xu, J., Zhao, Y., Luo, P., Lao, K. H., Margariti, A., Zhao, Q., Ding, W., Wang, G., Zhang, M., Zheng, L., Zhang, Z., Hu, Y., Wang, W., Shen, L., Smith, A., Shah, A. M., Wang, Q. & Zeng, L., Apr 2020, In : Stem Cells. 38, 4, p. 556-573 18 p.

    Research output: Contribution to journalArticle

  17. Cytokine mRNA degradation in cardiomyocytes restrains sterile inflammation in pressure overloaded hearts

    Omiya, S., Omori, Y., Taneike, M., Murakawa, T., Ito, J., Tanada, Y., Nishida, K., Yamaguchi, O., Satoh, T., Shah, A. M., Akira, S. & Otsu, K., 25 Feb 2020, In : Circulation. 141, 8, p. 667-677 11 p.

    Research output: Contribution to journalArticle

  18. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

    Delitsikou, V., Jarad, G., Rajaram, R. D., Ino, F., Rutkowski, J. M., Chen, C. D., Santos, C. X. C., Scherer, P. E., Abraham, C. R., Shah, A. M., Feraille, E., Miner, J. H. & de Seigneux, S., 1 Feb 2020, In : Faseb Journal. 34, 2, p. 2087-2104 18 p.

    Research output: Contribution to journalArticle

  19. Placental growth factor testing in suspected pre-eclampsia - Authors' reply

    Duhig, K., Myers, J., Seed, P. T., Shennan, A. H. & Chappell, L. C., 1 Feb 2020, In : Lancet. 395, 10221, p. 336-337 2 p.

    Research output: Contribution to journalLetter

  20. NADPH oxidase 2 mediates myocardial oxygen wasting in obesity

    Hafstad, A. D., Hansen, S. S., Lund, J., Santos, C. X. C., Boardman, N. T., Shah, A. M. & Aasum, E., Feb 2020, In : Antioxidants. 9, 2, 171.

    Research output: Contribution to journalArticle

  21. 32P-Postlabeling analysis of DNA adducts

    Phillips, D. H. & Arlt, V. M., 1 Jan 2020, Methods in Molecular Biology. Humana Press Inc, p. 291-302 12 p. (Methods in Molecular Biology; vol. 2102).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  22. Celastrol Alleviates Aortic Valve Calcification Via Inhibition of NADPH Oxidase 2 in Valvular Interstitial Cells

    Liu, H., Wang, L., Pan, Y., Wang, X., Ding, Y., Zhou, C., Shah, A. M., Zhao, G. & Zhang, M., 1 Jan 2020, In : JACC: Basic to Translational Science. 5, 1, p. 35-49 15 p.

    Research output: Contribution to journalArticle

  23. 2019
  24. Cardiac monocytes and macrophages after myocardial infarction

    Peet, C., Ivetic, A., Bromage, D. I. & Shah, A. M., 16 Dec 2019, In : Cardiovascular Research. cvz336.

    Research output: Contribution to journalArticle

  25. Lifestyle information and commercial weight management groups to support maternal postnatal weight management and positive lifestyle behaviour: the SWAN feasibility randomised controlled trial

    Bick, D., Taylor, C., Bhavnani, V., Healey, A., Seed, P., Roberts, S., Zasada, M., Avery, A., Craig, V., Khazaezadah, N., McMullen, S., O'Connor, S., Oki, B., Oteng Ntim, E., Poston, L. & Ussher, M., 5 Dec 2019, In : BJOG. 27 p.

    Research output: Contribution to journalArticle

  26. Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy

    Martinello, K. A., Meehan, C., Avdic-Belltheus, A., Lingam, I., Ragab, S., Hristova, M., Tann, C. J., Peebles, D., Hagberg, H., Wolfs, T. G. A. M., Klein, N., Tachtsidis, I., Golay, X., Kramer, B. W., Fleiss, B., Gressens, P. & Robertson, N. J., 1 Dec 2019, In : Scientific Reports. 9, 1, 10184.

    Research output: Contribution to journalArticle

  27. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

    Borges Manna, L., Ovadia, C., Lövgren-Sandblom, A., Chambers, J., Begum, S., Seed, P., Walker, I., Chappell, L. C., Marschall, H-U. & Williamson, C., 1 Dec 2019, In : BJOG. 126, 13, p. 1633-1640 8 p.

    Research output: Contribution to journalArticle

  28. Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain

    Van Steenwinckel, J., Schang, A-L., Krishnan, M. L., Degos, V., Delahaye-Duriez, A., Bokobza, C., Csaba, Z., Verdonk, F., Montané, A., Sigaut, S., Hennebert, O., Lebon, S., Schwendimann, L., Le Charpentier, T., Hassan-Abdi, R., Ball, G., Aljabar, P., Saxena, A., Holloway, R. K., Birchmeier, W. & 12 others, Baud, O., Rowitch, D., Miron, V., Chretien, F., Leconte, C., Besson, V. C., Petretto, E. G., Edwards, A. D., Hagberg, H., Soussi-Yanicostas, N., Fleiss, B. & Gressens, P., Dec 2019, In : Brain : a journal of neurology. 142, 12, p. 3806–3833

    Research output: Contribution to journalArticle

  29. Semantic computational analysis of anticoagulation use in atrial fibrillation from real world data

    Bean, D., Teo, J., Wu, H., Oliveira, R., Patel, R., Bendayan, R., Shah, A. M., Dobson, R. J. B. & Scott, P. A., 25 Nov 2019, In : PLOS One. 14, 11, e0225625.

    Research output: Contribution to journalArticle

  30. Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres

    Kaura, A., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F., O'Sullivan, M., Kharbanda, R., Lord, G. M., Melikian, N., Patel, R. S. & 4 others, Perera, D., Shah, A. M., Francis, D. P. & Mayet, J., 20 Nov 2019, In : BMJ (Clinical research ed.). 367, p. l6055 l6055.

    Research output: Contribution to journalArticle

  31. Prelamin A mediates myocardial inflammation in dilated and HIV-Associated cardiomyopathies

    Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M. A., Hayward, R., Ahmad, S. M., Vizcay-barrena, G., Protti, A., Zammit, P. S., Dos Remedios, C. G., Ehler, E., Shah, A. M. & Shanahan, C. M., 14 Nov 2019, In : JCI Insight. 4, 22, e126315.

    Research output: Contribution to journalArticle

  32. The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro

    Sborchia, M., De Prez, E. G., Antoine, M. H., Bienfait, L., Indra, R., Valbuena, G., Phillips, D. H., Nortier, J. L., Stiborová, M., Keun, H. C. & Arlt, V. M., 1 Nov 2019, In : Archives of Toxicology. 93, 11, p. 3345-3366 22 p.

    Research output: Contribution to journalArticle

  33. Pregnancy-related Acute Kidney Injury in pre-eclampsia: risk factors and renal outcomes

    Conti-Ramsden, F. I., Nathan, H. L., De Greeff, A., Hall, D. R., Seed, P. T., Chappell, L. C., Shennan, A. H. & Bramham, K., Nov 2019, In : Hypertension. 74, 5, p. 1144–1151 8 p.

    Research output: Contribution to journalArticle

  34. Therapies to limit myocardial injury in animal models of myocarditis: a systematic review and meta-analysis

    Silverblatt, J. A., Ziff, O. J., Dancy, L., Daniel, A., Carter, B. R., Scott, P. A., Sado, D., Shah, A. M. & Bromage, D. I., Nov 2019, In : Basic Research in Cardiology. 114, 6, 48.

    Research output: Contribution to journalArticle

  35. Endoplasmic reticulum and Golgi stress in microcephaly

    Passemard, S., Perez, F., Gressens, P. & El Ghouzzi, V., 30 Oct 2019, In : Cell Stress. 3, 12, p. 369-384 16 p.

    Research output: Contribution to journalReview article

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